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Questions and Answers
What is a primary therapeutic use of interferons?
What is a primary therapeutic use of interferons?
What is the mechanism of action of protease inhibitors?
What is the mechanism of action of protease inhibitors?
Which of the following is a common adverse effect associated with interferons?
Which of the following is a common adverse effect associated with interferons?
Which of the following drugs is classified as an antiviral agent for Hepatitis C?
Which of the following drugs is classified as an antiviral agent for Hepatitis C?
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What adverse effect is frequently associated with antiviral drugs?
What adverse effect is frequently associated with antiviral drugs?
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How do antiviral drugs inhibit viral DNA replication?
How do antiviral drugs inhibit viral DNA replication?
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What therapeutic role does thiamine play?
What therapeutic role does thiamine play?
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What adverse effect is associated with protease inhibitors?
What adverse effect is associated with protease inhibitors?
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What is a common therapeutic use of interferons?
What is a common therapeutic use of interferons?
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Which mechanism of action is associated with antiviral drugs?
Which mechanism of action is associated with antiviral drugs?
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What type of symptom is commonly associated with interferons?
What type of symptom is commonly associated with interferons?
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What type of patients benefit from the use of protease inhibitors?
What type of patients benefit from the use of protease inhibitors?
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Which adverse effect is linked to the use of antiviral agents?
Which adverse effect is linked to the use of antiviral agents?
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What is a key consideration when monitoring patients on interferons?
What is a key consideration when monitoring patients on interferons?
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What is the primary role of thiamine in the treatment of deficiencies?
What is the primary role of thiamine in the treatment of deficiencies?
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Which drug is an example of an antiviral for Hepatitis C treatment?
Which drug is an example of an antiviral for Hepatitis C treatment?
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Study Notes
Immune Stimulants
- Interferons are used to treat Hepatitis B and C.
- Interferons modulate the immune response and stimulate interferon receptor sites on non-infected cells.
- Interferons stimulate the production of antiviral proteins that prevent viruses from entering cells.
- Side effects include flu-like symptoms, bone marrow suppression, cardiotoxicity, dyspnea, alopecia, and gastrointestinal upset.
- Monitor complete blood count (CBC) levels, cardiac function, and liver function throughout therapy.
Antiviral Agents
- Antiretroviral protease inhibitors are used to treat Hepatitis C.
- These protease inhibitors block protease activity, rendering the HIV particle incapable of fusing with a cell and injecting itself into a cell.
- Side effects: gastrointestinal effects, changes in liver function, elevated cholesterol and triglyceride levels, fat redistribution, Stevens-Johnson syndrome.
Antiviral Drugs
- Antiviral drugs are used to treat Hepatitis C.
- These drugs inhibit viral DNA replication by competing with viral substrates to form shorter, non-effective DNA chains.
- Side effects include nausea, vomiting, headache, depression, paresthesia, neuropathy, rash, hair loss, and renal dysfunction.
Supplements
- Thiamine is a vitamin used to treat deficiencies.
- Thiamine is required for carbohydrate metabolism.
- Replaces thiamine if dietary deficiencies exist.
- Side effects and reactions are extremely rare.
Immune Stimulants
- Interferons are proteins that modify the immune response by stimulating interferon receptor sites on cells, leading to the production of antiviral proteins that prevent viruses from entering cells.
- Interferons are used to treat Hepatitis B and C.
- Common adverse effects include flu-like symptoms, bone marrow suppression, cardiotoxicity, dyspnea, alopecia, and gastrointestinal upset.
- Monitoring complete blood count (CBC) levels, cardiac function, and liver function throughout therapy is crucial.
Antiviral Agents
-
Antiretroviral protease inhibitors are used to treat Hepatitis C.
-
These drugs block protease activity, preventing HIV particles from fusing with and injecting themselves into cells.
-
Protease inhibitors can cause gastrointestinal effects, liver function changes, elevated cholesterol and triglyceride levels, fat redistribution, and Stevens-Johnson syndrome.
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Antiviral drugs like Ribavirin (Copegus) are also used to treat Hepatitis C.
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Ribavirin inhibits viral DNA replication by competing with viral substrates to form shorter, noneffective DNA chains.
-
Common side effects include nausea, vomiting, headache, depression, paresthesia, neuropathy, rash, hair loss, and renal dysfunction.
Supplements
- Thiamine is a vitamin used to treat deficiencies.
- It's essential for carbohydrate metabolism and is given to patients with deficiencies.
- Thiamine has minimal adverse effects.
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Description
This quiz covers immune stimulants, specifically interferons, and their role in treating Hepatitis B and C. It also explores the function and side effects of antiretroviral protease inhibitors and antiviral drugs used against Hepatitis C. Test your knowledge on these key concepts in immunology and virology.
