Immune Responses and Receptor Roles

TCR complex and CD28 (correct)

B7 molecules and CD28

CD4+ and CD8+ T cells

CTLA-4 and PD-1

To enhance costimulation by CD28

To activate responding T cells

To suppress the activation of responding T cells (correct)

To remove B7 molecules from the surface of APCs

CTLA-4 (correct)

TCR complex

PD-1

CD4+

<p>CTLA-4 and PD-1</p> Signup and view all the answers

<p>PD-1 inhibits kinase-dependent activating signals</p> Signup and view all the answers

<p>Checkpoint blockade</p> Signup and view all the answers

<p>They inhibit the activation of naive T cells and effector T cell differentiation</p> Signup and view all the answers