Podcast
Questions and Answers
Which neuroadaptive state occurs in response to long-term occupation of opioid receptors?
Which neuroadaptive state occurs in response to long-term occupation of opioid receptors?
- Sensitization
- Dependence (correct)
- Tolerance
- Hyperactivity
What is a common symptom of opioid withdrawal related to pain and irritability?
What is a common symptom of opioid withdrawal related to pain and irritability?
- Restlessness and insomnia (correct)
- Tranquilization
- Relaxation and sleep
- Euphoria
Which effect is NOT associated with acute opioid use?
Which effect is NOT associated with acute opioid use?
- Pupil constriction
- Increased blood pressure (correct)
- Pupil dilation
- Diarrhea
What is the primary effect of opioids on adenylyl cyclase and cAMP production?
What is the primary effect of opioids on adenylyl cyclase and cAMP production?
Which drug is mentioned as the most potent in the text regarding hallucinogens?
Which drug is mentioned as the most potent in the text regarding hallucinogens?
What is a common consequence of taking hallucinogenic drugs orally?
What is a common consequence of taking hallucinogenic drugs orally?
What is responsible for cannabinoid-induced memory impairment?
What is responsible for cannabinoid-induced memory impairment?
Which neurotransmitter is a full agonist at both CB1 and CB2 receptors?
Which neurotransmitter is a full agonist at both CB1 and CB2 receptors?
What is the impact of endocannabinoids on anxiety responses?
What is the impact of endocannabinoids on anxiety responses?
Which cannabinoid acts as a negative allosteric modulator of CB1 receptors?
Which cannabinoid acts as a negative allosteric modulator of CB1 receptors?
What is the effect of THC on regional brain activation based on brain imaging?
What is the effect of THC on regional brain activation based on brain imaging?
Which cognitive functions can be affected by marijuana use according to the text?
Which cognitive functions can be affected by marijuana use according to the text?
What cognitive process is impaired both acutely and chronically by cannabinoid exposure?
What cognitive process is impaired both acutely and chronically by cannabinoid exposure?
Which cognitive process shows possibly persistent effects according to the text?
Which cognitive process shows possibly persistent effects according to the text?
In chronic cannabinoid exposure, what cognitive process may be impaired depending on the frequency of use and age of onset?
In chronic cannabinoid exposure, what cognitive process may be impaired depending on the frequency of use and age of onset?
Which cognitive process is likely to show persistent effects on attention and psychomotor function with abstinence?
Which cognitive process is likely to show persistent effects on attention and psychomotor function with abstinence?
What effect of cannabinoid exposure is task- and dose-dependent according to the text?
What effect of cannabinoid exposure is task- and dose-dependent according to the text?
Which cognitive process shows possibly impaired executive function as a chronic effect of cannabinoid exposure?
Which cognitive process shows possibly impaired executive function as a chronic effect of cannabinoid exposure?
What potentially dangerous cardiovascular effects can be seen when α1 blockade is coupled with NE reuptake-blocking?
What potentially dangerous cardiovascular effects can be seen when α1 blockade is coupled with NE reuptake-blocking?
Which side effect is specifically associated with Selective Serotonin Reuptake Inhibitors (SSRIs)?
Which side effect is specifically associated with Selective Serotonin Reuptake Inhibitors (SSRIs)?
What life-threatening condition can occur when SSRIs are combined with other serotonergic agonists or drugs?
What life-threatening condition can occur when SSRIs are combined with other serotonergic agonists or drugs?
What is the primary advantage of Dual NE/5-HT modulators (SNRIs) over SSRIs according to the text?
What is the primary advantage of Dual NE/5-HT modulators (SNRIs) over SSRIs according to the text?
How does Mirtazapine reduce side effects according to the text?
How does Mirtazapine reduce side effects according to the text?
What effect does blocking α2-autoreceptors have on serotonergic cells?
What effect does blocking α2-autoreceptors have on serotonergic cells?
What is the best predictor of a good therapeutic response to psychedelic drugs?
What is the best predictor of a good therapeutic response to psychedelic drugs?
How do PCP and ketamine act as antagonists at the NMDA receptor?
How do PCP and ketamine act as antagonists at the NMDA receptor?
What effect does the NMDA receptor blockade by PCP and ketamine have on cortical GABAergic interneurons?
What effect does the NMDA receptor blockade by PCP and ketamine have on cortical GABAergic interneurons?
What is a common symptom induced by high doses of PCP and ketamine, resembling schizophrenia?
What is a common symptom induced by high doses of PCP and ketamine, resembling schizophrenia?
What is hypothesized as a key factor in the glutamate hypothesis of schizophrenia?
What is hypothesized as a key factor in the glutamate hypothesis of schizophrenia?
What effect did researchers find in human volunteers without prior exposure to ketamine?
What effect did researchers find in human volunteers without prior exposure to ketamine?
