Immune Response in Animals
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Questions and Answers

Which of the following statements about porcine circoviruses is true?

  • They cause reproductive disorders solely in female pigs.
  • They are present worldwide. (correct)
  • They cannot cause severe haemorrhagic diseases in pigs.
  • Porcine circoviruses are genetically and antigenically diverse.
  • What is a recognized method for preventing swine circovirus disease?

  • Antibiotics should be administered.
  • Natural remedies are the best approach.
  • Inactivated vaccines are available. (correct)
  • General hygienic measures only.
  • How long can swine circovirus be shed in excretions after recovery?

  • It cannot be shed at all.
  • For several weeks.
  • For several months. (correct)
  • For several days only.
  • Which of the following clinical signs is NOT associated with Swine circovirus?

    <p>Immediate loss of eyesight.</p> Signup and view all the answers

    What can be a consequence of PCV2 infection in pigs?

    <p>Retarded growth.</p> Signup and view all the answers

    Which factor is NOT a predisposing factor for Porcine Circovirus associated disease?

    <p>Weather conditions.</p> Signup and view all the answers

    What is the approximate incubation period for diseases caused by Porcine circoviruses?

    <p>2-4 weeks.</p> Signup and view all the answers

    Porcine circovirus-2 typically causes clinical signs mainly after which growth stage?

    <p>After weaning.</p> Signup and view all the answers

    What effect do maternal antibodies have on the efficacy of vaccinations?

    <p>They decrease the efficacy of vaccinations.</p> Signup and view all the answers

    Which statement is true regarding the concentration of immune globulins in colostrum after birth?

    <p>It decreases sharply after birth.</p> Signup and view all the answers

    What principle allows for differentiation between vaccinated and infected animals?

    <p>DIVA principle</p> Signup and view all the answers

    What type of vaccines can contain inactivated bacterial toxins?

    <p>Inactivated vaccines</p> Signup and view all the answers

    What type of immunoglobulins are transferred to newborn animals through colostrum?

    <p>Maternal antibodies</p> Signup and view all the answers

    Which of the following statements regarding adjuvants in vaccines is true?

    <p>They increase the efficacy of vaccines.</p> Signup and view all the answers

    Which statement is accurate about deletion vaccines?

    <p>They have certain parts of the genome missing.</p> Signup and view all the answers

    Which factor influences the efficacy of vaccination?

    <p>The health state of the vaccinated animals.</p> Signup and view all the answers

    Which methods can be used for the eradication of diseases in livestock?

    <p>Testing and selective breeding</p> Signup and view all the answers

    What is a necessary step when implementing the generation shift method of eradication?

    <p>Separating newborn animals from their mothers</p> Signup and view all the answers

    Which statement about the selection method of eradication is accurate?

    <p>Infected animals are removed from the herd</p> Signup and view all the answers

    When is the test and slaughter method most effectively applied?

    <p>In cases of low level of infection</p> Signup and view all the answers

    What is true about the herd replacement method?

    <p>The herd is replaced with infection-free animals</p> Signup and view all the answers

    Which aspect of the embryo transfer method is incorrect concerning eradication?

    <p>It can be used as an eradication technique</p> Signup and view all the answers

    Which method requires early weaning to be effective?

    <p>Generation shift</p> Signup and view all the answers

    Which statement about the immune response in newborn animals is correct?

    <p>Newborn animals exhibit local immune responses.</p> Signup and view all the answers

    What is a misconception regarding the use of vaccination in the selection method?

    <p>Vaccination is not allowed when using the selection method</p> Signup and view all the answers

    Which of the following factors can influence the susceptibility of animals to diseases?

    <p>The age of the animals.</p> Signup and view all the answers

    What is true regarding species specific resistance?

    <p>It ensures that some agents cannot infect certain hosts.</p> Signup and view all the answers

    What role does gastric juice play in host immunity?

    <p>It protects the host from infections.</p> Signup and view all the answers

    How does overcrowding affect infectious diseases?

    <p>It can facilitate the spread of several infectious diseases.</p> Signup and view all the answers

    Which statement accurately reflects the immune response of fetuses?

    <p>Fetuses do not have any immune response.</p> Signup and view all the answers

    What is the effect of mycotoxins on the immune system?

    <p>They can suppress the immune system’s activity.</p> Signup and view all the answers

    In the case of localized infections, where do the lesions typically appear?

    <p>At the site of pathogen entry.</p> Signup and view all the answers

    Which of the following statements is true regarding the prevention of Marek’s disease?

    <p>Vaccination of day-old chickens must be used for prevention.</p> Signup and view all the answers

    What is a common sign of duck viral enteritis?

    <p>Conjunctivitis</p> Signup and view all the answers

    Which of the following statements accurately describes the virulence of Marek’s disease viruses?

    <p>Highly virulent strains may overcome vaccine-induced protection.</p> Signup and view all the answers

    What misconception exists regarding the impact of duck plaque on domestic versus wild ducks?

    <p>Duck plaque is more severe in wild birds than in domestic ducks.</p> Signup and view all the answers

    Which of the following is a true statement about the duck plague virus?

    <p>It damages blood vessel endothelium.</p> Signup and view all the answers

    Why is treatment not considered the most effective control method for duck viral enteritis?

    <p>Prevention through general health management is more effective.</p> Signup and view all the answers

    Which statement is false regarding duck viral enteritis and duck plague?

    <p>Clinical cases are often seen in affected flocks.</p> Signup and view all the answers

    How does the duck plague virus affect ducks after recovery?

    <p>It can still be shed throughout their lives.</p> Signup and view all the answers

    Study Notes

    Immune Response

    • Newborn animals have a local immune response.
    • Fetuses do not have an active immune response.
    • Skin, mucous membranes, and mucus are part of the non-specific resistance system of the host.
    • The normal microflora of the gut is essential for animals.
    • The age of the animals can influence their susceptibility to a certain agent.
    • Certain medicines and agents can decrease the protection of the hosts.
    • Species-specific resistance means that certain agents cannot infect certain hosts.
    • Certain animal species are resistant against certain agents.
    • Chicken embryos are able to produce an immune response.
    • Cellular immune response is very important in the case of viral diseases.
    • Gastric juice can protect the host from infections.

    Factors Affecting Infectious Disease - Environment

    • Unfavourable environmental effects can predispose animals to diseases caused by facultative pathogenic agents.
    • Nutrition of the animals can influence the appearance of infectious diseases.
    • Environmental effects can influence the survival of the agents in the environment.
    • Mycotoxins can suppress the activity of the immune system.
    • Overcrowding can help the spreading of several infectious diseases.
    • Deserts can inhibit the spreading of several infectious diseases.

    Course of Infectious Diseases

    • Viruses causing generalised diseases generally replicate at the place of entry and in the regional lymph nodes.
    • The enteral absorption of immune globulins is decreasing after birth.
    • Maternal antibodies can decrease the efficacy of vaccination.
    • The immune globulin concentration of the colostrum decreases sharply after birth.
    • Maternal antibodies can decrease the immune response against vaccines.
    • Enteral lymphocytes can get from the dam to the newborn animal with colostrum.
    • Animals with epitheliochorial placenta have maternal immunity only from colostrum.
    • The endotheliochorial placenta prevents the transport of immunoglobulins to the foetus.
    • Homologous hyperimmune serum can provide about a year-long protection.

    Active Immunisation

    • Strains used in marker vaccines can be differentiated from the field strains.
    • Avirulent strains can be used in live vaccines.
    • The health state of the vaccinated animals can influence the efficacy of the vaccination.
    • Inactivated vaccines contain inactivated bacterial toxins.
    • Adjuvants in vaccines increase the efficacy of vaccines.
    • Attenuated strains can be used in live vaccines.
    • Deletion vaccines can only be used as live vaccines.
    • In the case of marker vaccines, the field strains and the vaccine strains can be differentiated.
    • Inactivated vaccines can contain the whole agents or their components.
    • The colostral immunoglobulins have no effect on the vaccination of the newborn animals.
    • DIVA principle can only be used if the animals are vaccinated with deletion vaccines.
    • According to the DIVA principle, infected and vaccinated animals can be differentiated.
    • Subunit vaccines contain only antigens of the agents.
    • Certain parts of the genome are missing from deletion vaccine strains.
    • Some genes are missing from the strains included in deletion vaccines.
    • Live vaccines can contain strains with lower virulence.
    • Live vaccines always contain avirulent agents.

    Eradication of Infectious Diseases

    • Eradication using the selection method is generally implemented in case of a low level of infection.
    • When eradication is made with the selection method, the infected animals are removed from the herd.
    • Selection, generation shift and herd replacement can be used for eradication.
    • Eradication using generation shift can be used in cattle herds.
    • Caesarean section is the only way of birth when eradication is carried out using the SPF method
    • Certain diseases can be eradicated with generation shift.
    • Herd replacement is the cheapest way of eradication of a disease.
    • Selection (test and slaughter) is a method of eradiation of a disease.
    • Selection method can be used for eradication of infectious diseases, when we remove infected animals.
    • In the case of generation shift, newborn animals are separated from the dam and kept isolated.
    • Embryo transfer cannot be used for eradication, since the embryo can be infected.
    • The selection method cannot be combined with vaccination.
    • Test and slaughter as an eradication method can be used in case of low level of infection.
    • There is no agent which can be eradicated by antibiotic treatment.
    • In the case of generation shift newborn animals have to be kept isolated from the parent animals.
    • In the case of herd replacement, the herd is replaced with infection-free animals.
    • In the case of the selection method of eradication the infected animals are taken out of the herd.
    • If eradication is made by the selection method, vaccination is forbidden.
    • Early weaning is necessary if the generation shift method of eradication is used.
    • Generation shift is a frequently used eradication method in swine.
    • Generation shift is a method of eradication of a disease.
    • In eradication by selective breeding, the seropositive animals are eliminated.
    • In eradication by selective breeding, only the animals shedding the bacteria are eliminated.
    • In eradication by selective breeding, vaccination cannot be used.
    • Eradication by selective breeding is not used anymore.
    • Selection (test and remove) is not used to eradicate a disease anymore.

    Porcine Circovirus

    • Porcine circoviruses are responsible for a variety of clinical conditions.
    • Porcine circoviruses are present worldwide.
    • Porcine circovirus can be transmitted by mice and rats.
    • Porcine circoviruses cause severe haemorrhagic diseases in pigs.
    • Porcine circoviruses are genetically and antigenically uniform.
    • Porcine circoviruses may cause a variety of diseases.
    • For prevention of Swine circovirus disease only general hygienic measures can be used.
    • Swine circovirus can cause retarded growth and strong immunosuppression.
    • Swine circovirus caused disease occurs worldwide, it is frequent.
    • For prevention of swine circovirus disease, inactivated vaccine is available.
    • Swine circovirus causes only respiratory signs
    • Swine circovirus may be shed in excretions for several months after recovery.
    • For prevention of Porcine circovirus disease vaccines are available.
    • The incubation period of Porcine circovirus caused disease is about 2-4 weeks.
    • Incubation period of porcine circovirus disease is short, some days.
    • Porcine circovirus-2 causes clinical signs mainly after weaning.
    • Predisposing factors for Porcine Circovirus associated disease can be: Vaccines.The virus variant.Virus strain.
    • PCV2 can cause: Enteric disorders.Disorders in the nervous system.Respiratory disease.Reproductions disorders.
    • Porcine circovirus-1 may damage the foetus.
    • Porcine circoviruses can be responsible for reproductive disorders.
    • Porcine circoviruses replicate in the heart of the foetus.
    • Porcine circovirus may cause inapparent infections.
    • Circovirus can be responsible for the Porcine Respiratory Disease Complex.
    • Reproductive disorders caused by Porcine circoviruses are only significant in North America.
    • Circovirus cause skin lesions in swine.

    PMWS

    • A clinical sign of PMWS can be a progressive weight loss.

    Marek's Disease

    • We can differentiate Marek’s disease from reticuloendotheliosis only by lab diagnostics methods.
    • General preventative measures and vaccination of day-old chickens must be used for the prevention of Marek’s disease.
    • Live attenuated strains are used for vaccination against Marek's disease.
    • The highly virulent strains of Marek’s disease may cause tumors in turkeys.
    • Marek’s disease viruses are uniform in their virulence.
    • Highly virulent Marek’s disease viruses may break through vaccine-induced protection.

    Duck Viral Enteritis/ Duck Plaque

    • Conjunctivitis is a frequent sign of duck viral enteritis.
    • Only sporadic clinical cases of duck viral enteritis are seen in an affected flock.
    • Mallards may transmit the duck enteritis virus to domestic ducks kept on lakes.
    • Liver dystrophy is a frequent lesion of duck viral enteritis (duck plaque).
    • Wild ducks may be persistently infected with duck plaque (duck enteritis) virus.
    • Duck plaque virus may be shed lifelong by animals recovered from the disease.
    • Duck plaque (viral enteritis) can’t cause high mortality without secondary bacterial infection.
    • Duck plaque and duck viral enteritis are two names of the same disease.
    • Duck viral enteritis is seldom fatal.
    • Treatment is the most effective control method for duck viral enteritis.
    • Duck plague is more severe in wild birds than in domestic ducks.
    • Duck plague virus damages blood vessel endothelium.
    • Duck plague only affects young ducklings.
    • Duck plague is only seen in day-old ducklings.
    • Duck viral enteritis is usually mild, osmotic diarrhoea.
    • Duck plague infects exclusively domestic and wild ducks.
    • Antibiotic treatment is the most effective control method for Duck Viral Enteritis.
    • Beak deformity is a typical sign of Duck Plague.
    • Muscovy duck are resistant to the Duck Viral Enteritis.

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    Description

    Explore the intricacies of how immune responses function in newborn and adult animals. This quiz covers various factors influencing immunity, including environmental effects, nutrition, and species-specific resistance. Test your knowledge on the immune system's role in protecting against diseases.

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