9 Questions
What is the hallmark of allergic diseases?
Production of IgE antibody
Where are mast cells abundant, making them the most common sites for immediate hypersensitivity reactions?
Under epithelia and connective tissues
Which type of immune response is characterized by the secretion of IL-4, IL-5, and IL-13?
Type 2 immune response
What triggers nonatopic hypersensitivity reactions?
Exercise
What do healthy individuals typically not respond to or have only harmless responses to?
Common environmental antigens
Which cells require previous T cell dependent allergen specific IgE production by B cells for sensitization?
Mast cells
What is the result of re-exposure to an allergen?
Activation of mast cells
Which component is NOT typically found in house dust that can trigger allergic reactions?
Pollen grains
What can be a consequence of Anaphylaxis in severe cases?
Cardiovascular collapse
Test your knowledge on hypersensitivity reactions and the role of IgE in immediate and late-phase reactions. Explore the clinical manifestations, pathological mechanisms, and the activation of mast cells by specific Fc receptors.
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