Identification of Cancer Stem Cells from Tumor Periphery
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Questions and Answers

What are the two main categories of cells found in sLA7-generated tumors?

Polygonal and mesenchyme-like cells

What distinguishes the polygonal and epithelial elongated cells in terms of tumor development?

Ability to sustain sphere formation serially and capacity for 3D organotypic growth

What is the capacity of mesenchyme-like cells in terms of expansion capacity ex vivo?

Limited

Name one method used to distinguish the different cell types in sLA7-generated tumors.

<p>Based on morphology and marker expression</p> Signup and view all the answers

What was one of the methods used to determine the tumor-formation potential of different cell types?

<p>Transplanting them into NOD-SCID mice</p> Signup and view all the answers

Which cells were characterized by their morphology as polygonal and epithelial elongated?

<p>Polygonal and epithelial elongated cells</p> Signup and view all the answers

Who were the authors of the research mentioned in the text?

<p>I.Z., R.A.R., and R.D.</p> Signup and view all the answers

What are the main differences between polygonal and mesenchyme-like cells in sLA7-generated tumors?

<p>Expansion capacity and properties related to tumor development</p> Signup and view all the answers

How many distinct cell types were reported to be present in sLA7-generated tumors?

<p>Three</p> Signup and view all the answers

What properties of cells were analyzed in the research mentioned in the text?

<p>Sphere formation, 3D organotypic growth, and tumor-formation potential</p> Signup and view all the answers

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