Cell Injury II
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Questions and Answers

Which of the following is an example of cell injury with a defined etiology?

  • Apoptosis
  • Chemical injury (correct)
  • Necrosis
  • Pathologic calcification
  • What are the two biochemical processes that occur in tissue necrosis?

  • Enzymatic digestion and protein denaturation (correct)
  • Caseous and gangrenous
  • Coagulation and liquefaction
  • Hypoxia and ischemia
  • Which type of necrosis involves the enzymatic digestion of tissue?

  • Liquefactive necrosis (correct)
  • Gangrenous necrosis
  • Coagulation necrosis
  • Caseous necrosis
  • Which type of necrosis occurs in any tissue where there is a focus of bacterial or fungal infection?

    <p>Liquefactive necrosis (D)</p> Signup and view all the answers

    What type of necrosis is seen in the lung and any other tissue affected by tuberculosis?

    <p>Caseous necrosis (C)</p> Signup and view all the answers

    What is the abnormal deposition of calcium salts and other types of minerals in tissues called?

    <p>Calcification (B)</p> Signup and view all the answers

    What type of calcification occurs in areas of necrosis despite normal circulating levels of calcium?

    <p>Dystrophic calcification (D)</p> Signup and view all the answers

    Which organelle is very active in the injured cell and may form autophagosomes to digest damaged organelles or misfolded proteins?

    <p>Lysosomes (C)</p> Signup and view all the answers

    What is the most common form of necrosis that occurs in a number of solid organs?

    <p>Coagulation necrosis (A)</p> Signup and view all the answers

    Which process occurs in necrosis and involves enzymatic digestion and denaturation of proteins?

    <p>Autolysis (D)</p> Signup and view all the answers

    What type of cell death occurs in regulated events, usually involves isolated cells, and does not elicit an inflammatory response?

    <p>Apoptosis (C)</p> Signup and view all the answers

    Which of the following is an example of chemical injury?

    <p>Direct combination of chemicals with an organelle or molecule (C)</p> Signup and view all the answers

    What is the difference between hypoxia and ischemia?

    <p>ischemia is the loss of blood supply due to impeded arterial flow, while hypoxia is a lack of oxygen (A)</p> Signup and view all the answers

    What happens when blood supply is lost and tissue oxygen levels fall?

    <p>Glycolytic pathways are upregulated, lowering intracellular pH (C)</p> Signup and view all the answers

    What can trigger necrotic or apoptotic death of a cell?

    <p>Opening of mitochondrial permeability transition pore (C)</p> Signup and view all the answers

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