Hypothalamic Nucleus and Stress Response
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Questions and Answers

What is the main role of CRH in the stress response?

  • Inhibiting glucocorticoid synthesis
  • Regulating cortisol levels (correct)
  • Activating insulin production
  • Inducing vasopressin secretion

    • Where does ACTH induce glucocorticoid synthesis?

  • Adrenal medulla
  • Heart
  • Skin
  • Adrenal cortex (correct)

    • What happens to the secretion of CRH and ACTH due to feedback from glucocorticoids during prolonged stress?

  • It does not change (correct)
  • It decreases
  • It increases
  • It stops completely

    • What is the condition called when stress-induced ACTH and glucocorticoid hypersecretion fail to inhibit additional pituitary ACTH secretion?

    <p>Permissive facilitation</p> Signup and view all the answers

    Apart from ACTH, what other factors influence glucocorticoid secretion?

    <p>Vasopressin and angiotensin</p> Signup and view all the answers

    In which brain area does multiple external and internal stimuli activate neurons to synthesize and secrete CRH?

    <p>Paraventricular hypothalamic nucleus</p> Signup and view all the answers

    What is the major role of glucocorticoids?

    <p>Mobilization of energy stores</p> Signup and view all the answers

    What can cortisol levels reach within a few hours of starting major surgery?

    <p>Four- to five-fold the normal baseline value</p> Signup and view all the answers

    Which hormone has a more potent mineralocorticoid effect than cortisol?

    <p>Aldosterone</p> Signup and view all the answers

    What stimulates the production of aldosterone?

    <p>Stress induced CRH and ACTH secretion</p> Signup and view all the answers

    What happens to aldosterone production after several hours of sustained adrenal cortex stimulation by ACTH?

    <p>Begins to wane and returns to normal or low levels within 24 hours</p> Signup and view all the answers

    What does RAAS stimulation induce?

    <p>Sustained higher concentrations of aldosterone</p> Signup and view all the answers

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