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Hypothalamic Nucleus and Stress Response

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Hypothalamic Nucleus and Stress Response

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Questions and Answers

What is the main role of CRH in the stress response?

Inhibiting glucocorticoid synthesis

Regulating cortisol levels (correct)

Activating insulin production

Inducing vasopressin secretion

Where does ACTH induce glucocorticoid synthesis?

Adrenal medulla

Heart

Skin

Adrenal cortex (correct)

What happens to the secretion of CRH and ACTH due to feedback from glucocorticoids during prolonged stress?

It does not change (correct)

It decreases

It increases

It stops completely

What is the condition called when stress-induced ACTH and glucocorticoid hypersecretion fail to inhibit additional pituitary ACTH secretion?

Permissive facilitation Signup and view all the answers

Apart from ACTH, what other factors influence glucocorticoid secretion?

Vasopressin and angiotensin Signup and view all the answers

In which brain area does multiple external and internal stimuli activate neurons to synthesize and secrete CRH?

Paraventricular hypothalamic nucleus Signup and view all the answers

What is the major role of glucocorticoids?

Mobilization of energy stores Signup and view all the answers

What can cortisol levels reach within a few hours of starting major surgery?

Four- to five-fold the normal baseline value Signup and view all the answers

Which hormone has a more potent mineralocorticoid effect than cortisol?

Aldosterone Signup and view all the answers

What stimulates the production of aldosterone?

Stress induced CRH and ACTH secretion Signup and view all the answers

What happens to aldosterone production after several hours of sustained adrenal cortex stimulation by ACTH?

Begins to wane and returns to normal or low levels within 24 hours Signup and view all the answers

What does RAAS stimulation induce?

Sustained higher concentrations of aldosterone Signup and view all the answers