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Immediate Hypersensitivity Reaction Quiz
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Immediate Hypersensitivity Reaction Quiz

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Questions and Answers

What is the primary role of the high-affinity IgE receptor found on mast cells and basophils?

  • Promoting histamine release
  • Mediating allergic response (correct)
  • Initiating vasodilation
  • Preventing anaphylaxis
  • What is the consequence of multiple IgE antibodies becoming crosslinked on the mast cell surface?

  • Initiation of vascular permeability
  • Inhibition of mast cell degranulation
  • Activation of receptor tyrosine kinases (correct)
  • Prevention of bronchoconstriction
  • Which condition results from clumping of receptors on mast cells and basophils?

  • Respiratory instability (correct)
  • Epinephrine treatment
  • Hemodynamic instability
  • Systemic vasoconstriction
  • What is the key effect of degranulation of mast cells and basophils in type I hypersensitivity reactions?

    <p>Release of inflammatory mediators</p> Signup and view all the answers

    Which outcome is likely if type I hypersensitivity reactions are not promptly treated with epinephrine?

    <p>Progression to death</p> Signup and view all the answers

    What is the primary effector cell involved in immediate hypersensitivity reactions mediated by IgE antibodies?

    <p>Mast cells</p> Signup and view all the answers

    What is the function of lgE produced by B-lymphocytes specific for allergens?

    <p>Binds to lgE Fc receptors on mast cells and basophils</p> Signup and view all the answers

    What is required to cause degranulation of mast cells and basophils in response to allergen exposure?

    <p>Cross-linking of lgE molecules by two molecules of allergen</p> Signup and view all the answers

    Which of the following mediators is NOT released during the immediate phase of an allergic reaction?

    <p>Chemokines</p> Signup and view all the answers

    What is the main function of leukotrienes released during the late phase of an allergic reaction?

    <p>Attract inflammatory cells like eosinophils</p> Signup and view all the answers

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