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Immediate Hypersensitivity Reaction Quiz

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Immediate Hypersensitivity Reaction Quiz

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Questions and Answers

What is the primary role of the high-affinity IgE receptor found on mast cells and basophils?

Promoting histamine release

Mediating allergic response (correct)

Initiating vasodilation

Preventing anaphylaxis

What is the consequence of multiple IgE antibodies becoming crosslinked on the mast cell surface?

Initiation of vascular permeability

Inhibition of mast cell degranulation

Activation of receptor tyrosine kinases (correct)

Prevention of bronchoconstriction

Which condition results from clumping of receptors on mast cells and basophils?

Respiratory instability (correct)

Epinephrine treatment

Hemodynamic instability

Systemic vasoconstriction

What is the key effect of degranulation of mast cells and basophils in type I hypersensitivity reactions?

Release of inflammatory mediators (A) Signup and view all the answers

Which outcome is likely if type I hypersensitivity reactions are not promptly treated with epinephrine?

Progression to death (A) Signup and view all the answers

What is the primary effector cell involved in immediate hypersensitivity reactions mediated by IgE antibodies?

Mast cells (B) Signup and view all the answers

What is the function of lgE produced by B-lymphocytes specific for allergens?

Binds to lgE Fc receptors on mast cells and basophils (A) Signup and view all the answers

What is required to cause degranulation of mast cells and basophils in response to allergen exposure?

Cross-linking of lgE molecules by two molecules of allergen (C) Signup and view all the answers

Which of the following mediators is NOT released during the immediate phase of an allergic reaction?

Chemokines (A) Signup and view all the answers

What is the main function of leukotrienes released during the late phase of an allergic reaction?

Attract inflammatory cells like eosinophils (B) Signup and view all the answers