Podcast
Questions and Answers
What is the primary role of the high-affinity IgE receptor found on mast cells and basophils?
What is the primary role of the high-affinity IgE receptor found on mast cells and basophils?
- Promoting histamine release
- Mediating allergic response (correct)
- Initiating vasodilation
- Preventing anaphylaxis
What is the consequence of multiple IgE antibodies becoming crosslinked on the mast cell surface?
What is the consequence of multiple IgE antibodies becoming crosslinked on the mast cell surface?
- Initiation of vascular permeability
- Inhibition of mast cell degranulation
- Activation of receptor tyrosine kinases (correct)
- Prevention of bronchoconstriction
Which condition results from clumping of receptors on mast cells and basophils?
Which condition results from clumping of receptors on mast cells and basophils?
- Respiratory instability (correct)
- Epinephrine treatment
- Hemodynamic instability
- Systemic vasoconstriction
What is the key effect of degranulation of mast cells and basophils in type I hypersensitivity reactions?
What is the key effect of degranulation of mast cells and basophils in type I hypersensitivity reactions?
Which outcome is likely if type I hypersensitivity reactions are not promptly treated with epinephrine?
Which outcome is likely if type I hypersensitivity reactions are not promptly treated with epinephrine?
What is the primary effector cell involved in immediate hypersensitivity reactions mediated by IgE antibodies?
What is the primary effector cell involved in immediate hypersensitivity reactions mediated by IgE antibodies?
What is the function of lgE produced by B-lymphocytes specific for allergens?
What is the function of lgE produced by B-lymphocytes specific for allergens?
What is required to cause degranulation of mast cells and basophils in response to allergen exposure?
What is required to cause degranulation of mast cells and basophils in response to allergen exposure?
Which of the following mediators is NOT released during the immediate phase of an allergic reaction?
Which of the following mediators is NOT released during the immediate phase of an allergic reaction?
What is the main function of leukotrienes released during the late phase of an allergic reaction?
What is the main function of leukotrienes released during the late phase of an allergic reaction?
