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Questions and Answers
What is the main cause of Hyperosmolar Hyperglycemic State (HHS)?
What is the main cause of Hyperosmolar Hyperglycemic State (HHS)?
How can lipodystrophy be prevented?
How can lipodystrophy be prevented?
What is the first priority in the treatment of Diabetic Ketoacidosis?
What is the first priority in the treatment of Diabetic Ketoacidosis?
What are the causes of hypoglycemia?
What are the causes of hypoglycemia?
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Which condition results in the body burning fat for fuel and the production of ketones?
Which condition results in the body burning fat for fuel and the production of ketones?
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What is the characteristic sign of hyperglycemia?
What is the characteristic sign of hyperglycemia?
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What are the microvascular complications of diabetes?
What are the microvascular complications of diabetes?
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How does Hyperosmolar Hyperglycemic State (HHS) differ from Diabetic Ketoacidosis (DKA)?
How does Hyperosmolar Hyperglycemic State (HHS) differ from Diabetic Ketoacidosis (DKA)?
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What are the signs and symptoms of Hypoglycemia?
What are the signs and symptoms of Hypoglycemia?
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What are the macrovascular changes associated with diabetes?
What are the macrovascular changes associated with diabetes?
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Which of the following diagnostic tests would be most appropriate to confirm an endocrine disorder related to the pituitary gland?
Which of the following diagnostic tests would be most appropriate to confirm an endocrine disorder related to the pituitary gland?
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Which disorder is characterized by excessive growth due to hypersecretion of growth hormone from the pituitary gland in adulthood?
Which disorder is characterized by excessive growth due to hypersecretion of growth hormone from the pituitary gland in adulthood?
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What disorder arises from a deficiency of all anterior pituitary hormones?
What disorder arises from a deficiency of all anterior pituitary hormones?
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Which disorder is characterized by excessive production of antidiuretic hormone (ADH) resulting in water retention and dilutional hyponatremia?
Which disorder is characterized by excessive production of antidiuretic hormone (ADH) resulting in water retention and dilutional hyponatremia?
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Which disorder is caused by an underactive thyroid gland resulting in a decreased metabolic rate and other symptoms?
Which disorder is caused by an underactive thyroid gland resulting in a decreased metabolic rate and other symptoms?
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Which disorder is characterized by excessive production of thyroid hormones leading to symptoms such as weight loss, rapid heart rate, and heat intolerance?
Which disorder is characterized by excessive production of thyroid hormones leading to symptoms such as weight loss, rapid heart rate, and heat intolerance?
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Which disorder is characterized by an overproduction of parathyroid hormone, leading to elevated calcium levels in the blood?
Which disorder is characterized by an overproduction of parathyroid hormone, leading to elevated calcium levels in the blood?
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Which disorder results from the adrenal cortex producing too much cortisol, leading to weight gain, particularly in the upper body, and thinning of the skin?
Which disorder results from the adrenal cortex producing too much cortisol, leading to weight gain, particularly in the upper body, and thinning of the skin?
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Which disorder arises from the adrenal cortex not producing enough cortisol and aldosterone, leading to fatigue, muscle weakness, and low blood pressure?
Which disorder arises from the adrenal cortex not producing enough cortisol and aldosterone, leading to fatigue, muscle weakness, and low blood pressure?
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What is the main cause of hyperparathyroidism?
What is the main cause of hyperparathyroidism?
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Which symptom is specifically associated with hypoparathyroidism?
Which symptom is specifically associated with hypoparathyroidism?
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What is the primary effect of excess cortisol in Cushing's syndrome?
What is the primary effect of excess cortisol in Cushing's syndrome?
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What is the major cause of Addison's disease?
What is the major cause of Addison's disease?
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Which symptom is NOT associated with Addisonian crisis?
Which symptom is NOT associated with Addisonian crisis?
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What is the characteristic symptom of pheochromocytoma?
What is the characteristic symptom of pheochromocytoma?
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What is the normal range for A1c (glycated hemoglobin)?
What is the normal range for A1c (glycated hemoglobin)?
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Which test requires fasting the night before and checking blood glucose 2 hours after drinking a solution?
Which test requires fasting the night before and checking blood glucose 2 hours after drinking a solution?
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What is the normal range for blood glucose in the Fasting Glucose Test (FPG)?
What is the normal range for blood glucose in the Fasting Glucose Test (FPG)?
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What is the main effect of hypoparathyroidism?
What is the main effect of hypoparathyroidism?
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Which of the following is NOT a cause of short stature?
Which of the following is NOT a cause of short stature?
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What is the substance that helps to control fluid balance by reducing urination?
What is the substance that helps to control fluid balance by reducing urination?
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What causes Graves' disease?
What causes Graves' disease?
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What is the difference between acromegaly and gigantism?
What is the difference between acromegaly and gigantism?
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What is the condition in which the body makes too much ADH, resulting in water intoxication along with sodium deficiency?
What is the condition in which the body makes too much ADH, resulting in water intoxication along with sodium deficiency?
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What are the signs and symptoms of exophthalmos (proptosis)?
What are the signs and symptoms of exophthalmos (proptosis)?
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What is the characteristic sign of hyperthyroidism?
What is the characteristic sign of hyperthyroidism?
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What causes goiter?
What causes goiter?
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What are the primary causes of diabetes insipidus?
What are the primary causes of diabetes insipidus?
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What is the difference between diabetes insipidus and syndrome of inappropriate antidiuretic hormone (SIADH)?
What is the difference between diabetes insipidus and syndrome of inappropriate antidiuretic hormone (SIADH)?
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Which disorder results from the adrenal cortex producing too much cortisol, leading to weight gain, particularly in the upper body, and thinning of the skin?
Which disorder results from the adrenal cortex producing too much cortisol, leading to weight gain, particularly in the upper body, and thinning of the skin?
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What is the characteristic sign of hypoparathyroidism?
What is the characteristic sign of hypoparathyroidism?
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What is the condition in which the body makes too much antidiuretic hormone (ADH), resulting in water intoxication along with sodium deficiency?
What is the condition in which the body makes too much antidiuretic hormone (ADH), resulting in water intoxication along with sodium deficiency?
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Which disorder arises from a deficiency of all anterior pituitary hormones?
Which disorder arises from a deficiency of all anterior pituitary hormones?
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What are the primary causes of diabetes insipidus?
What are the primary causes of diabetes insipidus?
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What causes Graves' disease?
What causes Graves' disease?
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Which diagnostic test would be most appropriate to confirm an endocrine disorder related to the pituitary gland?
Which diagnostic test would be most appropriate to confirm an endocrine disorder related to the pituitary gland?
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Which of the following is a recommended foot care practice for individuals with diabetes?
Which of the following is a recommended foot care practice for individuals with diabetes?
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What is the main cause of Hyperosmolar Hyperglycemic State (HHS)?
What is the main cause of Hyperosmolar Hyperglycemic State (HHS)?
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What are the signs and symptoms of Diabetic Ketoacidosis (DKA)?
What are the signs and symptoms of Diabetic Ketoacidosis (DKA)?
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What is the first priority in the treatment of Diabetic Ketoacidosis (DKA)?
What is the first priority in the treatment of Diabetic Ketoacidosis (DKA)?
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What is the characteristic sign of hyperglycemia?
What is the characteristic sign of hyperglycemia?
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What are the macrovascular changes associated with diabetes?
What are the macrovascular changes associated with diabetes?
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What are the microvascular complications of diabetes?
What are the microvascular complications of diabetes?
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What causes Diabetic Nephropathy?
What causes Diabetic Nephropathy?
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What is the main treatment for Hyperosmolar Hyperglycemic State (HHS)?
What is the main treatment for Hyperosmolar Hyperglycemic State (HHS)?
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What is the main cause of Cushing's syndrome?
What is the main cause of Cushing's syndrome?
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What causes pheochromocytoma?
What causes pheochromocytoma?
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What is the primary effect of excessive growth hormone (GH) production in adults?
What is the primary effect of excessive growth hormone (GH) production in adults?
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Which substance helps to control fluid balance by reducing urination?
Which substance helps to control fluid balance by reducing urination?
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What is the characteristic symptom of hypothyroidism?
What is the characteristic symptom of hypothyroidism?
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Which disorder is characterized by an underactive thyroid gland resulting in a decreased metabolic rate?
Which disorder is characterized by an underactive thyroid gland resulting in a decreased metabolic rate?
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What is the substance that can lead to water intoxication and sodium deficiency when produced excessively by the body?
What is the substance that can lead to water intoxication and sodium deficiency when produced excessively by the body?
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What is the primary effect of excess cortisol in Cushing's syndrome?
What is the primary effect of excess cortisol in Cushing's syndrome?
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Which of the following is NOT a cause of hypoparathyroidism?
Which of the following is NOT a cause of hypoparathyroidism?
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What is the substance that helps to control fluid balance by reducing urination?
What is the substance that helps to control fluid balance by reducing urination?
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What causes Graves' disease?
What causes Graves' disease?
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What is the characteristic sign of hyperglycemia?
What is the characteristic sign of hyperglycemia?
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What is the difference between acromegaly and gigantism?
What is the difference between acromegaly and gigantism?
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What are the primary causes of hyperglycemia?
What are the primary causes of hyperglycemia?
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What is the main cause of Diabetic Nephropathy?
What is the main cause of Diabetic Nephropathy?
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What is the characteristic sign of Diabetic Ketoacidosis (DKA)?
What is the characteristic sign of Diabetic Ketoacidosis (DKA)?
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What is the primary effect of excess cortisol in Cushing's syndrome?
What is the primary effect of excess cortisol in Cushing's syndrome?
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Which disorder results from an underactive thyroid gland resulting in a decreased metabolic rate?
Which disorder results from an underactive thyroid gland resulting in a decreased metabolic rate?
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What is the difference between Diabetes insipidus and Syndrome of Inappropriate Antidiuretic Hormone (SIADH)?
What is the difference between Diabetes insipidus and Syndrome of Inappropriate Antidiuretic Hormone (SIADH)?
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What are the macrovascular changes associated with diabetes?
What are the macrovascular changes associated with diabetes?
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What causes pheochromocytoma?
What causes pheochromocytoma?
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What is the substance that helps to control fluid balance by reducing urination?
What is the substance that helps to control fluid balance by reducing urination?
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What causes goiter?
What causes goiter?
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Study Notes
- Endocrine disorders can be diagnosed through diagnostic tests such as lab/blood tests, urinalysis, imaging tests, radioactive tests, thyroid scans, and biopsy.
- Disorders of the anterior lobe of the pituitary gland include acromegaly, gigantism, short stature (formerly known as dwarfism), and Simmonds disease (panhypopituitarism).
- Acromegaly is characterized by the overgrowth of growth hormone in adults, causing enlargement of cranium and lower jaw, bulging forehead, enlarged tongue, enormous hands and feet, thick lips, and large nose.
- Gigantism occurs when excessive GH production happens prior to puberty, leading to abnormal growth in height.
- Short stature can result from GH deficiency in childhood, causing a person to grow to only a few feet in height but with normal proportions, along with fatigue, weakness, excess body fat, decreased muscle and bone mass, cardiovascular and cerebrovascular disease, psychological disturbances, and decreased quality of life.
- Diuretics are substances that promote diuresis, the increased production of urine, while antidiuretics help control fluid balance by reducing urination.
- Syndrome of Inappropriate Antidiuretic Hormone (SIADH) is a condition where the body produces too much ADH, leading to water intoxication and sodium deficiency, causing symptoms such as oliguria, headache, cramps or tremors, seizures, nausea or vomiting, irritability, depressed mood, memory impairment, stupor or coma, personality changes, lethargy, increased specific gravity, and weight gain.
- Diabetes Insipidus is a condition where the body underproduces ADH, leading to the excretion of large amounts of dilute urine, causing symptoms such as thirst, dehydration, dry mucous membranes, and low urine output.
- Thyroid disorders include hyperthyroidism (Graves disease, exophthalmos, thyroid storm), hypothyroidism (myxedema, cretinism, goiter, Hashimoto), and disorders of the parathyroid gland (hyperparathyroidism, hypoparathyroidism).
- Hyperparathyroidism involves increased secretion of parathyroid hormone, leading to hypercalcemia and hypophosphatemia, causing symptoms such as osteomalacia, pathological fractures, weakness, nausea and constipation, kidney stones, UTI, disorientation, and tetany.
- Hypoparathyroidism results from inadequate circulating PTH, leading to hypocalcemia and hyperphosphatemia, causing symptoms such as tremors, muscular irritability, labyrinthian spasm, decreased cardiac output, dysrhythmias, Chvosteks and Trousseau signs.
- Cushing's Syndrome is caused by excess cortisol in the body, leading to round and hairy appearance, buffalo hump, moon face, thin arms and legs, wavy abdomen, hyperglycemia, depression, suicidal ideations, and bone demineralization.
- Addison's disease is a condition where the adrenal glands produce insufficient cortisol and aldosterone, leading to fatigue, weight loss, low blood pressure, and hypoglycemia.
- Addisonian crisis is a medical emergency caused by a sudden drop in cortisol levels, leading to symptoms such as dehydration, electrolyte imbalance, hypotension, and hypoglycemia.
- Hyperaldosteronism is a condition where the adrenal glands produce too much aldosterone, leading to increased sodium reabsorption and potassium excretion, causing symptoms such as high blood pressure, muscle cramps, and weakness.
- Pheochromocytoma is a rare tumor of the adrenal medulla that produces and secretes excessive amounts of catecholamines, leading to symptoms such as high blood pressure, sweating, tremors, and palpitations.- Adrenal glands do not produce sufficient cortisol and aldosterone due to destruction or degeneration of the adrenal cortex.
- Causes of Addison's disease include massive infections (e.g. tuberculosis), hemorrhage, pituitary malfunction, long-term steroid therapy, and cancer.
- Addison's disease symptoms: dark pigmentation of skin, dehydration, hypoglycemia, hyponatremia, hyperkalemia, nausea, anorexia, hypotension, weight loss, dizziness, craving for salt, intolerance to cold, and adrenal crisis when functions reach critically low levels.
- Glucocorticoids (cortisol) and mineralocorticoids (aldosterone) are important hormones secreted by the adrenal cortex.
- Cortisol helps regulate metabolism, immune response, and stress response. Aldosterone helps maintain water and electrolyte balance.
- In Addison's disease, the adrenal glands do not secrete enough cortisol, leading to hypoglycemia, dehydration, and other symptoms. They also do not secrete enough aldosterone, leading to fluid and electrolyte imbalances.
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Description
Test your knowledge about hyperparathyroidism, its signs, symptoms, and treatment options including thyroid lobectomy. Learn about the condition involving increased secretion of parathyroid hormone (PTH) and its effects on the body.