Human Herpes Virus 6 and Roseola Disease

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6 Questions

At what age range does Roseola typically occur?

Between 6 months and 2 years

What is the typical duration of the fever phase of Roseola?

4 days

What is the characteristic of the rash that appears in Roseola?

Diffuse maculopapular lacy rash that spares the face

What is the target cell type of HHV-6 infection?

CD4 cells

What is the complication that can occur due to high fever in Roseola?

Febrile seizures

What is the current approach to treating Roseola?

Symptomatic management, such as keeping the patient cool

Study Notes

Human Herpes Virus 6 (HHV-6)

  • HHV-6 is a double-stranded DNA virus.
  • Also known as the 6th disease or "roSIXola".

Roseola

  • A childhood illness caused by HHV-6 infection.
  • Occurs between 6 months and 2 years of age.
  • Characterized by a high fever, followed by a diffuse maculopapular lacy rash that spares the face.
  • Fever lasts for 4 days, then subsides, and the rash appears.
  • Rash is predominantly found on the trunk.

Symptoms

  • High fever, often over 104 degrees, which can cause febrile seizures.
  • Febrile fevers, characterized by trembling with awe.
  • Patient may sweat profusely.

Treatment

  • No FDA-approved treatment available.
  • Patients are advised to keep the child cool to manage the fever.
  • HHV-8 is a different herpes virus that causes Kaposi's sarcoma.
  • Both HHV-6 and HHV-8 were barely discussed in the lecture.

This quiz covers the virology and characteristics of Human Herpes Virus 6, its association with Roseola disease, and its effects on the human body, particularly in children.

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