Human Genetic Diversity: Mutations and Polymorphisms

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is responsible for the genetically determined variability among humans?

  • Genetically determined phenotypic variability
  • Sequence of nuclear DNA (correct)
  • Chromosome number alterations
  • Variation in mitochondrial DNA

Which type of DNA sequence differences have little or no effect on phenotype?

  • Variation in mitochondrial DNA
  • Genetically determined phenotypic variability
  • Chromosome number alterations
  • Small fraction of different DNA sequences (correct)

What is responsible for causing disease in humans?

  • Changes in DNA sequence of individual genes (correct)
  • Changes in mitochondrial genomes
  • Chromosome number alterations
  • Genetically determined phenotypic variability

What do gene mutations alter?

<p>Individual genes (C)</p> Signup and view all the answers

What is nearly 99.9% identical between any two humans?

<p>Sequence of nuclear DNA (A)</p> Signup and view all the answers

Which type of mutation may lead to the formation of a variant protein with altered properties?

<p>A single nucleotide substitution in a DNA sequence (C)</p> Signup and view all the answers

What is the term for mutations occurring in cancer and cannot be transmitted?

<p>Somatic mutations (C)</p> Signup and view all the answers

What mechanism introduces errors during the normal process of DNA replication?

<p>Failure to repair DNA after damage (D)</p> Signup and view all the answers

Which type of DNA changes are usually corrected through proofreading mechanisms?

<p>Errors introduced during the normal process of DNA replication (A)</p> Signup and view all the answers

What percentage of replication errors are corrected by a series of DNA repair enzymes?

<p>99.9% (D)</p> Signup and view all the answers

What is responsible for the genetically determined variability among humans?

<p>Small fraction of DNA sequence differences (D)</p> Signup and view all the answers

Which type of DNA changes may have little or no effect on phenotype?

<p>Large amounts of base changes (A)</p> Signup and view all the answers

What process alters chromosome number, structure, or individual genes?

<p>Gene mutations (D)</p> Signup and view all the answers

Which type of DNA sequence differences are directly responsible for causing disease?

<p>Gene mutations (A)</p> Signup and view all the answers

Which type of mutation may lead to complete loss of expression of a gene or the formation of a variant protein with altered properties?

<p>Missense mutation (A)</p> Signup and view all the answers

What is the term for mutations that occur in cells that will populate the germline and are usually inherited?

<p>Germline mutations (D)</p> Signup and view all the answers

What mechanism is responsible for correcting more than 99.9% of errors of DNA replication?

<p>Proofreading mechanisms (A)</p> Signup and view all the answers

What are the two basic mechanisms of gene mutations?

<p>Error during DNA replication and DNA repair failure (B)</p> Signup and view all the answers

Which type of DNA changes is usually corrected through proofreading mechanisms?

<p>Replication-related DNA changes (A)</p> Signup and view all the answers

Flashcards are hidden until you start studying

More Like This

Unraveling Human Genetic Diversity
5 questions
Unraveling Human Genetic Diversity
10 questions
Human Genetic Diversity
30 questions

Human Genetic Diversity

HopefulPoltergeist avatar
HopefulPoltergeist
Tema 6. Mutaciones y Polimorfismos
39 questions
Use Quizgecko on...
Browser
Browser