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Questions and Answers
Non-granular leucocytes contain specific and non-specific granules.
Non-granular leucocytes contain specific and non-specific granules.
False
Monocytes have eccentric and kidney-shaped nucleus.
Monocytes have eccentric and kidney-shaped nucleus.
True
Eosinophils have functional correlation with basophils and plasma cells.
Eosinophils have functional correlation with basophils and plasma cells.
False
The largest nucleated blood cells are Lymphocytes.
The largest nucleated blood cells are Lymphocytes.
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Natural killer cells can kill virally infected cells directly by a natural immune response.
Natural killer cells can kill virally infected cells directly by a natural immune response.
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B lymphocytes are developed in the spleen.
B lymphocytes are developed in the spleen.
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Lymphocytosis is caused by acute infections.
Lymphocytosis is caused by acute infections.
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The life span of white blood cells is 4 months.
The life span of white blood cells is 4 months.
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Study Notes
Leucocytes
- Non-granular leucocytes contain specific and non-specific granules.
Monocytes
- Have eccentric and kidney-shaped nucleus.
- Have large, eccentric, bi-lobed, pale nucleus with clear nucleolus.
Null-lymphocytes
- Can kill some cancer cells by a natural immune response.
Eosinophils
- Have functional correlation with basophils and plasma cells.
- Increase in number during treatment with cortisone.
- Attracted to terminate allergic reaction by Eosinophil chemotactic factor (ECF).
Neutrophils
- Secrete collagenase enzyme to help its migration in connective tissue.
- Granules contain phagocytin (Bactericidal), lactoferrin (Bacteriostatic), and histamine.
Lymphocytes
- Not the largest nucleated blood cells.
- Can differentiate into plasma cells during immune responses.
- Percentage in the blood is 30-40%.
- Diameter of a small lymphocyte is 6-9 μm.
- B-lymphocytes are not developed in the spleen.
- T-lymphocytes acquire surface receptors in the thymus.
Basophils
- Nucleus is irregular in shape (mostly S-shaped).
- Secrete histaminases and sulphatase to destroy histamine and heparin.
- Basophilia occurs in liver cirrhosis.
Natural Killer Cells
- Have non-T, non-B receptors and can kill virally infected cells directly by a natural immune response.
Immune Response
- T-Lymphocytes help and activate B-Lymphocytes.
- Helper T Cells secrete perforins that produce pores in the membrane of the foreign cell leading to its lysis.
Clinical Conditions
- Lymphocytosis is caused by acute infections.
- Hemorrhagic anemia is due to excessive destruction of RBCs due to abnormal shape or abnormal Hb content.
- Anaphylactic shock is caused by severe allergy, leading to generalized vasodilation and a severe drop in blood pressure.
- Lymphocytic Leukemia is a type of cancer of the blood characterized by an abnormal decrease of lymphocytes.
- Pus produces Pyrogens which elevate body temperature (fever) to inhibit bacterial growth.
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Description
This quiz covers the characteristics of different types of blood cells, including their shape, function, and properties. Learn about the unique features of leukocytes, neutrophils, lymphocytes, monocytes, and more.
