Lifespan of Leukocytes Quiz
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Questions and Answers

What is the primary function of platelets?

  • To prevent excessive internal or external bleeding (correct)
  • To produce white blood cells
  • To regulate blood pressure
  • To transport oxygen in the blood

Where are platelet granules found?

  • In the bone marrow
  • In the white blood cells
  • In the megakaryocyte cytoplasm (correct)
  • In the red blood cells

What triggers the activation of platelets?

  • Exposure to collagen of basal lamina and connective tissue (correct)
  • Exposure to glucose
  • Exposure to oxygen
  • Exposure to nitrogen

How do platelets help in wound repair?

<p>By secreting chemicals like platelet-derived growth factor (PDGF) and transforming growth factor beta (TGF beta) (A)</p> Signup and view all the answers

What is the typical lifespan of platelets?

<p>About 10 days (B)</p> Signup and view all the answers

What is the size of platelets?

<p>2-4 um in diameter (B)</p> Signup and view all the answers

Which substance promotes adhesion of platelets to endothelial cells?

<p>VON WILLEBRAND FACTOR (C)</p> Signup and view all the answers

What do platelets primarily help to form after an injury?

<p>Blood clots (C)</p> Signup and view all the answers

What do platelet granules contain?

<p>VON WILLEBRAND FACTOR and PLATELET FACTOR IV (D)</p> Signup and view all the answers

What triggers the activation of platelets?

<p>Exposure to collagen of basal lamina and connective tissue (A)</p> Signup and view all the answers

Which of the following is a primary lymphoid organ?

<p>Thymus (B)</p> Signup and view all the answers

Which structure is responsible for the maturation of B lymphocytes?

<p>Bone marrow (C)</p> Signup and view all the answers

What is the function of high endothelial venules (HEVs) in the lymphatic system?

<p>Lymphocyte migration (C)</p> Signup and view all the answers

Which cell type is responsible for antigen presentation in the lymphatic system?

<p>Dendritic cell (C)</p> Signup and view all the answers

What is the clinical significance of thymic involution?

<p>Reduced immune response (C)</p> Signup and view all the answers

Which types of epithelioreticular cells are present in the thymus cortex?

<p>Type I, Type II, and Type III (C)</p> Signup and view all the answers

What is the structural feature of the thymus that establishes domains called thymic lobules?

<p>Trabeculae (D)</p> Signup and view all the answers

What is the function of Type VI epithelioreticular cells in the thymus?

<p>Production of thymosin and thymopoietin (C)</p> Signup and view all the answers

What process ensures that surviving lymphocytes in the thymus are responsive to appropriate stimuli and not self-reactive?

<p>Negative selection (A)</p> Signup and view all the answers

What clinical condition is caused by the failure of epithelioreticular cells to develop T cell precursors in the thymus?

<p>DiGeorge Syndrome (B)</p> Signup and view all the answers

Where are lymphatic nodules primarily found?

<p>Large intestine (D)</p> Signup and view all the answers

What is the function of high endothelial venules (HEVs) in the lymph nodes?

<p>Transport antigens (B)</p> Signup and view all the answers

What is the main difference between primary and secondary lymphatic nodules?

<p>Presence of germinal centers (C)</p> Signup and view all the answers

Which organ was once thought to be vestigial but actually contains large numbers of lymphatic nodules?

<p>Appendix (A)</p> Signup and view all the answers

What is the function of M cells in Peyer's patches?

<p>Present antigens to T cells (C)</p> Signup and view all the answers

Where do T lymphocytes migrate to after leaving the HEV in the lymph node?

<p>Outer cortex (C)</p> Signup and view all the answers

What is the function of stave cells in the red pulp of the spleen?

<p>Phagocytosis of RBCs (C)</p> Signup and view all the answers

What is the role of periarterial lymphatic sheath (PALS) in the spleen?

<p>Monitoring blood-borne antigens (A)</p> Signup and view all the answers

What is the main function of splenic sinuses in the red pulp?

<p>Traversal of healthy RBCs (C)</p> Signup and view all the answers

Where do B lymphocytes encounter blood-borne antigens in the spleen?

<p>Red pulp (D)</p> Signup and view all the answers

Where are the high endothelial venules (HEVs) located?

<p>In the deep cortex of the lymph node (C)</p> Signup and view all the answers

What is the main function of M cells in Peyer's patches?

<p>Transporting antigens from the intestine to immune cells (A)</p> Signup and view all the answers

Where are lymphatic nodules typically found?

<p>Along lymphatic vessels (C)</p> Signup and view all the answers

What triggers activation of platelets?

<p>Adhesion to collagen (A)</p> Signup and view all the answers

What is the exact function of the appendix?

<p>The exact function remains unclear (C)</p> Signup and view all the answers

What is the clinical significance of DiGeorge Syndrome?

<p>It causes failure of epithelioreticular cells to develop T cell precursors in the thymus (A)</p> Signup and view all the answers

What is the main function of Hassall’s corpuscles in the thymus?

<p>Maturation of T lymphocytes (A)</p> Signup and view all the answers

Where are PALs (periarteriolar lymphatic sheaths) located?

<p>In the white pulp of the spleen (C)</p> Signup and view all the answers

What is the primary function of MALT (mucosa associated lymphoid tissue)?

<p>Defense against gastrointestinal pathogens (D)</p> Signup and view all the answers

What triggers the activation of platelets?

<p>Exposure to collagen or tissue factor (B)</p> Signup and view all the answers

What is the main function of type V epithelioreticular cells in the thymus?

<p>Deletion of self-reactive T cells (C)</p> Signup and view all the answers

What is the main function of type II epithelioreticular cells in the thymus cortex?

<p>Antigen presentation to immature lymphocytes (C)</p> Signup and view all the answers

What is the structural feature responsible for creating 'privileged' areas for T cell development in the thymus?

<p>Continuous (non-fenestrated) endothelium (D)</p> Signup and view all the answers

Which type of epithelioreticular cells is involved in forming a cytoplasmic reticulum within the thymus parenchyma?

<p>Type I epithelioreticular cells (D)</p> Signup and view all the answers

What is the function of Hassall's corpuscles in the thymus?

<p>Production of lymphocytes maturation factors (D)</p> Signup and view all the answers

Where do B lymphocytes encounter blood-borne antigens in the spleen?

<p>Red pulp (C)</p> Signup and view all the answers

What is the main function of high endothelial venules (HEVs) in the lymph nodes?

<p>Migration of lymphocytes from the blood into the lymph node (C)</p> Signup and view all the answers

What is the primary function of platelets?

<p>Promoting blood coagulation (C)</p> Signup and view all the answers

What is the clinical significance of thymic involution?

<p>Increased risk of autoimmune diseases (B)</p> Signup and view all the answers

What process ensures that surviving lymphocytes in the thymus are responsive to appropriate stimuli and not self-reactive?

<p>Negative selection (C)</p> Signup and view all the answers

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