Lifespan of Leukocytes Quiz

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What is the primary function of platelets?

To prevent excessive internal or external bleeding (correct)

To produce white blood cells

To regulate blood pressure

To transport oxygen in the blood

Where are platelet granules found?

In the bone marrow

In the white blood cells

In the megakaryocyte cytoplasm (correct)

In the red blood cells

What triggers the activation of platelets?

Exposure to collagen of basal lamina and connective tissue (correct)

Exposure to glucose

Exposure to oxygen

Exposure to nitrogen

How do platelets help in wound repair?

By secreting chemicals like platelet-derived growth factor (PDGF) and transforming growth factor beta (TGF beta) Signup and view all the answers

What is the typical lifespan of platelets?

About 10 days Signup and view all the answers

What is the size of platelets?

2-4 um in diameter Signup and view all the answers

Which substance promotes adhesion of platelets to endothelial cells?

VON WILLEBRAND FACTOR Signup and view all the answers

What do platelets primarily help to form after an injury?

Blood clots Signup and view all the answers

What do platelet granules contain?

VON WILLEBRAND FACTOR and PLATELET FACTOR IV Signup and view all the answers

What triggers the activation of platelets?

Exposure to collagen of basal lamina and connective tissue Signup and view all the answers

Which of the following is a primary lymphoid organ?

Thymus Signup and view all the answers

Which structure is responsible for the maturation of B lymphocytes?

Bone marrow Signup and view all the answers

What is the function of high endothelial venules (HEVs) in the lymphatic system?

Lymphocyte migration Signup and view all the answers

Which cell type is responsible for antigen presentation in the lymphatic system?

Dendritic cell Signup and view all the answers

What is the clinical significance of thymic involution?

Reduced immune response Signup and view all the answers

Which types of epithelioreticular cells are present in the thymus cortex?

Type I, Type II, and Type III Signup and view all the answers

What is the structural feature of the thymus that establishes domains called thymic lobules?

Trabeculae Signup and view all the answers

What is the function of Type VI epithelioreticular cells in the thymus?

Production of thymosin and thymopoietin Signup and view all the answers

What process ensures that surviving lymphocytes in the thymus are responsive to appropriate stimuli and not self-reactive?

Negative selection Signup and view all the answers

What clinical condition is caused by the failure of epithelioreticular cells to develop T cell precursors in the thymus?

DiGeorge Syndrome Signup and view all the answers

Where are lymphatic nodules primarily found?

Large intestine Signup and view all the answers

What is the function of high endothelial venules (HEVs) in the lymph nodes?

Transport antigens Signup and view all the answers

What is the main difference between primary and secondary lymphatic nodules?

Presence of germinal centers Signup and view all the answers

Which organ was once thought to be vestigial but actually contains large numbers of lymphatic nodules?

Appendix Signup and view all the answers

What is the function of M cells in Peyer's patches?

Present antigens to T cells Signup and view all the answers

Where do T lymphocytes migrate to after leaving the HEV in the lymph node?

Outer cortex Signup and view all the answers

What is the function of stave cells in the red pulp of the spleen?

Phagocytosis of RBCs Signup and view all the answers

What is the role of periarterial lymphatic sheath (PALS) in the spleen?

Monitoring blood-borne antigens Signup and view all the answers

What is the main function of splenic sinuses in the red pulp?

Traversal of healthy RBCs Signup and view all the answers

Where do B lymphocytes encounter blood-borne antigens in the spleen?

Red pulp Signup and view all the answers

Where are the high endothelial venules (HEVs) located?

In the deep cortex of the lymph node Signup and view all the answers

What is the main function of M cells in Peyer's patches?

Transporting antigens from the intestine to immune cells Signup and view all the answers

Where are lymphatic nodules typically found?

Along lymphatic vessels Signup and view all the answers

What triggers activation of platelets?

Adhesion to collagen Signup and view all the answers

What is the exact function of the appendix?

The exact function remains unclear Signup and view all the answers

What is the clinical significance of DiGeorge Syndrome?

It causes failure of epithelioreticular cells to develop T cell precursors in the thymus Signup and view all the answers

What is the main function of Hassall’s corpuscles in the thymus?

Maturation of T lymphocytes Signup and view all the answers

Where are PALs (periarteriolar lymphatic sheaths) located?

In the white pulp of the spleen Signup and view all the answers

What is the primary function of MALT (mucosa associated lymphoid tissue)?

Defense against gastrointestinal pathogens Signup and view all the answers

What triggers the activation of platelets?

Exposure to collagen or tissue factor Signup and view all the answers

What is the main function of type V epithelioreticular cells in the thymus?

Deletion of self-reactive T cells Signup and view all the answers

What is the main function of type II epithelioreticular cells in the thymus cortex?

Antigen presentation to immature lymphocytes Signup and view all the answers

What is the structural feature responsible for creating 'privileged' areas for T cell development in the thymus?

Continuous (non-fenestrated) endothelium Signup and view all the answers

Which type of epithelioreticular cells is involved in forming a cytoplasmic reticulum within the thymus parenchyma?

Type I epithelioreticular cells Signup and view all the answers

What is the function of Hassall's corpuscles in the thymus?

Production of lymphocytes maturation factors Signup and view all the answers

Where do B lymphocytes encounter blood-borne antigens in the spleen?

Red pulp Signup and view all the answers

What is the main function of high endothelial venules (HEVs) in the lymph nodes?

Migration of lymphocytes from the blood into the lymph node Signup and view all the answers

What is the primary function of platelets?

Promoting blood coagulation Signup and view all the answers

What is the clinical significance of thymic involution?

Increased risk of autoimmune diseases Signup and view all the answers

What process ensures that surviving lymphocytes in the thymus are responsive to appropriate stimuli and not self-reactive?

Negative selection Signup and view all the answers

Lifespan of Leukocytes Quiz

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Questions and Answers

What is the primary function of platelets?

Where are platelet granules found?

What triggers the activation of platelets?

How do platelets help in wound repair?

What is the typical lifespan of platelets?

What is the size of platelets?

Which substance promotes adhesion of platelets to endothelial cells?

What do platelets primarily help to form after an injury?

What do platelet granules contain?

What triggers the activation of platelets?

Which of the following is a primary lymphoid organ?

Which structure is responsible for the maturation of B lymphocytes?

What is the function of high endothelial venules (HEVs) in the lymphatic system?

Which cell type is responsible for antigen presentation in the lymphatic system?

What is the clinical significance of thymic involution?

Which types of epithelioreticular cells are present in the thymus cortex?

What is the structural feature of the thymus that establishes domains called thymic lobules?

What is the function of Type VI epithelioreticular cells in the thymus?

What process ensures that surviving lymphocytes in the thymus are responsive to appropriate stimuli and not self-reactive?

What clinical condition is caused by the failure of epithelioreticular cells to develop T cell precursors in the thymus?

Where are lymphatic nodules primarily found?

What is the function of high endothelial venules (HEVs) in the lymph nodes?

What is the main difference between primary and secondary lymphatic nodules?

Which organ was once thought to be vestigial but actually contains large numbers of lymphatic nodules?

What is the function of M cells in Peyer's patches?

Where do T lymphocytes migrate to after leaving the HEV in the lymph node?

What is the function of stave cells in the red pulp of the spleen?

What is the role of periarterial lymphatic sheath (PALS) in the spleen?

What is the main function of splenic sinuses in the red pulp?

Where do B lymphocytes encounter blood-borne antigens in the spleen?

Where are the high endothelial venules (HEVs) located?

What is the main function of M cells in Peyer's patches?

Where are lymphatic nodules typically found?

What triggers activation of platelets?

What is the exact function of the appendix?

What is the clinical significance of DiGeorge Syndrome?

What is the main function of Hassall’s corpuscles in the thymus?

Where are PALs (periarteriolar lymphatic sheaths) located?

What is the primary function of MALT (mucosa associated lymphoid tissue)?

What triggers the activation of platelets?

What is the main function of type V epithelioreticular cells in the thymus?

What is the main function of type II epithelioreticular cells in the thymus cortex?

What is the structural feature responsible for creating 'privileged' areas for T cell development in the thymus?

Which type of epithelioreticular cells is involved in forming a cytoplasmic reticulum within the thymus parenchyma?

What is the function of Hassall's corpuscles in the thymus?

Where do B lymphocytes encounter blood-borne antigens in the spleen?

What is the main function of high endothelial venules (HEVs) in the lymph nodes?

What is the primary function of platelets?

What is the clinical significance of thymic involution?

What process ensures that surviving lymphocytes in the thymus are responsive to appropriate stimuli and not self-reactive?

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