MD1 Sem 2
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Questions and Answers

Explain the significance of the rectovesical pouch in male anatomy.

The rectovesical pouch serves as a space where fluid can accumulate between the bladder and the rectum, which can be clinically important.

What structures does the peritoneum cover in the female reproductive system?

In females, the peritoneum covers the bladder and uterus, extending on both sides of the reproductive tract.

Describe the orientation of the pelvic organs relative to the pelvic inlet.

The pelvic organs are oriented parallel to the pelvic inlet, with the urinary tract anterior, reproductive tract in the middle, and the digestive tract posterior.

What role does the mesonephric duct retention play in male reproductive anatomy?

<p>Retention of the mesonephric duct is essential for the formation and connection of the male reproductive tract to the urinary tract.</p> Signup and view all the answers

How does the peritoneum contribute to the separation of abdominal and pelvic organs?

<p>The parietal peritoneum separates the abdominal organs from pelvic organs by forming a continuous covering that encompasses these structures.</p> Signup and view all the answers

What are the two main components of the fetal-maternal interface?

<p>Chorionic plate and basal plate.</p> Signup and view all the answers

What is the primary role of chorionic villi in the placenta?

<p>To carry fetal vessels and facilitate gas, waste, and hormonal exchange.</p> Signup and view all the answers

How does the fetal-maternal blood barrier function?

<p>It prevents mixing of fetal and maternal blood.</p> Signup and view all the answers

What spinal levels correspond to the sympathetic nerve supply in males?

<p>T10 to L2.</p> Signup and view all the answers

Which nerve is primarily responsible for parasympathetic innervation in the pelvis?

<p>Pelvic splanchnic nerves.</p> Signup and view all the answers

What is the role of spiral arteries at the basal plate?

<p>They open into the intervillous space for nutrient delivery.</p> Signup and view all the answers

What does the term 'suspensory lig. anastamosis' refer to?

<p>It relates to the connections that support the position of the uterus.</p> Signup and view all the answers

Describe the significance of the fetal-maternal interface during menstruation.

<p>It cycles with menstruation in the absence of conception.</p> Signup and view all the answers

How does the orientation of the pelvic viscera differ between males and females?

<p>The pelvic viscera in males and females differ mainly due to variations in pelvic inlet angles and organ positioning, impacting reproductive anatomy.</p> Signup and view all the answers

What is identified as the pelvic inlet angle, and how does it vary between sexes?

<p>The pelvic inlet angle is approximately $60-80^ ext{o}$ to the horizontal, exhibiting dimorphic characteristics between males and females.</p> Signup and view all the answers

Describe the relationship between the peritoneum and the pelvic cavity regarding pouches and mesenteries.

<p>The peritoneum forms various pouches and mesenteries that support pelvic organs, specifically differing in structure between male and female pelvises.</p> Signup and view all the answers

What two features characterize the rectum's position in relation to the sacrum?

<p>The rectum curves in alignment with the sacrum and forms a tight angle at the junction of the anal and urogenital triangles.</p> Signup and view all the answers

What anatomical landmark is typically aligned with the tip of the coccyx in the male pelvis?

<p>The superior surface of the pubic symphysis is typically level with the tip of the coccyx in the male pelvis.</p> Signup and view all the answers

Identify the major blood supply to the pelvic organs and its significance.

<p>The internal iliac arteries supply blood to the pelvic organs, critical for their nourishment and overall function.</p> Signup and view all the answers

How does the anatomy of the placenta relate to its function during fetal development?

<p>The placenta's anatomy, designed for efficient nutrient and gas exchange, directly relates to its role in sustaining fetal development.</p> Signup and view all the answers

What is the significance of the pubic symphysis being parallel to the upper sacrum in pelvic orientation?

<p>The parallelism of the pubic symphysis to the upper sacrum aids in determining the overall pelvic alignment and stability.</p> Signup and view all the answers

What are the two main pouches formed by the bladder and uterus as well as the uterus and rectum?

<p>The two main pouches are the Uterovesical pouch and the Rectouterine pouch (of Douglas).</p> Signup and view all the answers

Identify one clinical significance of the Rectouterine pouch (of Douglas).

<p>Fluid accumulation or infectious debris can accumulate in this pouch, impacting the uterus and potentially leaking to other structures.</p> Signup and view all the answers

How does the structure of the rectum differ from that of the colon?

<p>The rectum lacks taenia coli and has a continuous longitudinal smooth muscle coating.</p> Signup and view all the answers

What does the middle third of the rectum contain in males and females?

<p>In males, it contains seminal vesicles, vas deferens, and ureters; in females, it contains the uterus, cervix, and ureters.</p> Signup and view all the answers

What is the significance of the pararectal fossae in clinical practice?

<p>They allow for palpation and access to the pelvic cavity during examinations or surgeries.</p> Signup and view all the answers

Explain the role of the detrusor muscle in the bladder.

<p>The detrusor muscle contracts to expel urine from the bladder, facilitating bladder function.</p> Signup and view all the answers

What anatomical relationships are important to consider during surgical access to the prostate?

<p>The prostate can be accessed through the anal canal, which has close anatomical relations with the lower third of the rectum.</p> Signup and view all the answers

What is the function of the trigone in the bladder?

<p>The trigone serves as the internal area for the entry of ureters and exit of the urethra.</p> Signup and view all the answers

What is the position of the uterus in relation to the cervix and bladder?

<p>The uterus is anteflexed on the cervix, curving to lie over the bladder.</p> Signup and view all the answers

What anatomical structures contribute to the development of the vagina?

<p>The vagina probably developed from the paramesonephric tubes and peritoneal ligaments.</p> Signup and view all the answers

What is the significance of the broad ligament in the context of the uterus and uterine tubes?

<p>The broad ligament allows the uterus to expand and permits movement of the uterine tubes.</p> Signup and view all the answers

Describe the relationship between the ovaries and the uterine tubes.

<p>The infundibullae and fimbriae of the uterine tubes are very close to the ovaries.</p> Signup and view all the answers

What is the role of mesenteries in the context of organs that expand significantly?

<p>Mesenteries allow organs that expand a lot, like the uterus, to have the necessary support and mobility.</p> Signup and view all the answers

How are the urethra and vagina positioned in relation to the pelvic brim?

<p>The urethra and vagina are approximately parallel to the pelvic brim.</p> Signup and view all the answers

What does the suspensory ligament of the ovary reflect over?

<p>The suspensory ligament of the ovary is a peritoneal reflection over the ovary.</p> Signup and view all the answers

From what view can the ovary be observed when considering its relationship to the uterus?

<p>The ovary is visible from a posterior view in relation to the uterus.</p> Signup and view all the answers

What is the primary function of the uterine ligaments mentioned in supporting the uterus?

<p>They help maintain the position of the uterus in the pelvic cavity.</p> Signup and view all the answers

How does the round ligament assist in securing the uterus?

<p>It runs through the inguinal canal and anchors the uterus to the labia majora.</p> Signup and view all the answers

Which arteries branch off the internal iliac to supply blood to the uterus?

<p>The uterine artery and the inferior vesicular artery supply blood to the uterus.</p> Signup and view all the answers

Why is the structure of the uterine ligaments essential for facilitating an upright posture during pregnancy?

<p>They provide stability and prevent excessive movement or displacement of the uterus.</p> Signup and view all the answers

What vascular structures are associated with the umbilical artery in relation to pregnancy?

<p>The umbilical artery delivers oxygenated blood from the placenta to the fetus.</p> Signup and view all the answers

How does the inferior rectal artery relate to the internal pudendal artery in the pelvic region?

<p>The inferior rectal artery branches from the internal pudendal artery to supply the anal region.</p> Signup and view all the answers

What is the blood supply pattern for the superior vesicular artery?

<p>It branches off the umbilical artery, supplying the bladder and surrounding structures.</p> Signup and view all the answers

Can you identify the location where the round ligament continues after traversing the inguinal canal?

<p>It continues into the labia majora.</p> Signup and view all the answers

What is the position of the pelvic inlet in relation to the horizontal plane?

<p>About 60-80° (B)</p> Signup and view all the answers

Which structure is aligned with the tip of the coccyx in the male pelvis?

<p>Superior surface of the pubic symphysis (D)</p> Signup and view all the answers

What characterizes the rectum's curvature in relation to the sacrum?

<p>It curves significantly at the junction with the anal triangle (B)</p> Signup and view all the answers

Which of the following statements correctly describes the relationship between the pubic symphysis and the upper sacrum?

<p>The pubic symphysis is approximately parallel to the upper sacrum (A)</p> Signup and view all the answers

What is the primary vascular supply to the pelvic organs?

<p>Internal iliac arteries (B)</p> Signup and view all the answers

Which pelvic feature distinguishes male and female orientations?

<p>Shape of the pelvic inlet (A)</p> Signup and view all the answers

What is a defining characteristic of the rectovesical pouch?

<p>It is unique to male anatomy (A)</p> Signup and view all the answers

In the pelvic cavity, what is the significance of the tight angle at the junction of the anal and urogenital triangles?

<p>It impacts the curvature of the rectum (A)</p> Signup and view all the answers

Which blood supply pathway correctly describes the uterine contribution?

<p>Arcuate artery to radial artery to spiral artery (C)</p> Signup and view all the answers

What mesenteric ligament is associated with the ovarian blood supply?

<p>Suspensory ligament (C)</p> Signup and view all the answers

What term describes the connection between the placenta and uterine blood supply?

<p>Uterine anastomosis (B)</p> Signup and view all the answers

What happens to spiral arteries during menstrual shedding?

<p>They constrict causing reduced blood supply (D)</p> Signup and view all the answers

Which anatomical structure communicates directly with the placenta?

<p>Uterine artery (D)</p> Signup and view all the answers

Which component primarily supplies blood to the ovaries?

<p>Ovarian artery (D)</p> Signup and view all the answers

What is the essential role of anastomosis in the blood supply of the uterus?

<p>To ensure adequate oxygen supply during pregnancy (C)</p> Signup and view all the answers

Which artery is involved in the transition of blood supply from the ovarian artery before reaching the uterus?

<p>Uterine artery (B)</p> Signup and view all the answers

What is the primary function of the myometrium in relation to autonomic innervation?

<p>It has receptors that respond equally to both neural and endocrine signals. (B)</p> Signup and view all the answers

Which lymphatic nodes are primarily involved in drainage from the deep pouch structures of the perineum?

<p>Internal iliac nodes (C)</p> Signup and view all the answers

In females, which lymphatic nodes are responsible for draining the gonads?

<p>Ovarian nodes (D)</p> Signup and view all the answers

What is true regarding the flow of lymphatic drainage from superficial pouch structures?

<p>They first drain into inguinal nodes before joining the internal iliac route. (A)</p> Signup and view all the answers

How does the lymphatic drainage pattern of the gonads vary between males and females?

<p>Females have ovarian nodes that drain parts of the uterus. (B)</p> Signup and view all the answers

What is the primary anatomical difference between the rectum and the colon?

<p>The rectum lacks taenia coli. (C)</p> Signup and view all the answers

Which anatomical structure does NOT contribute to the contents of the upper third of the rectum?

<p>Vas deferens (A)</p> Signup and view all the answers

What type of muscle is found in the bladder wall?

<p>Smooth muscle (C)</p> Signup and view all the answers

In female anatomy, which structures are found within the middle third of the rectum?

<p>Uterus and cervix (D)</p> Signup and view all the answers

Which anatomical pouch can lead to fluid accumulation, especially in females?

<p>Rectouterine pouch (of Douglas) (D)</p> Signup and view all the answers

What is a significant clinical implication of having direct contact between the lower third of the rectum and surrounding structures?

<p>Increased risk of rectal perforation (D)</p> Signup and view all the answers

Which area serves as the internal entry and exit point for urine in the bladder?

<p>Trigone (C)</p> Signup and view all the answers

Which anatomical relationship is crucial in surgical access to the prostate?

<p>Direct access through the anal canal (B)</p> Signup and view all the answers

What structure protects the urethra during an erection?

<p>Corpus spongiosum (B)</p> Signup and view all the answers

What is the main consequence of a retroverted cervix during pregnancy?

<p>Potential difficulty in fetal positioning (D)</p> Signup and view all the answers

Which layer of tissue provides structural rigidity to the penis during an erection?

<p>Tunica albuginea (D)</p> Signup and view all the answers

Which of the following arteries is responsible for the blood flow during penile erection?

<p>Deep arteries (D)</p> Signup and view all the answers

What is the primary composition of the blood sinuses within the penis?

<p>Thick fibrous tissue (A)</p> Signup and view all the answers

How are the dorsal vessels of the penis associated with blood flow?

<p>They facilitate drainage during flaccidity (D)</p> Signup and view all the answers

What happens to the blood flow in the corpora cavernosa during an erection?

<p>It experiences high-pressure influx (D)</p> Signup and view all the answers

What is the structural role of the deep (Buck’s) fascia in the penis?

<p>It houses the dorsal vessels (A)</p> Signup and view all the answers

What anatomical structures are involved in forming the trigone area of the bladder?

<p>Ureters and mesonephric ducts (D)</p> Signup and view all the answers

During which week of development does the septum divide the cloaca?

<p>6th week (D)</p> Signup and view all the answers

Which statement regarding the ductus deferens is correct?

<p>It crosses over the ureters. (D)</p> Signup and view all the answers

What is the primary function of the ampullae of the ductus deferens?

<p>Storage and maturation of sperm (D)</p> Signup and view all the answers

What anatomical feature forms the apex of the bladder?

<p>Urachus (C)</p> Signup and view all the answers

Which structure does not receive ducts in the prostate?

<p>Bulbourethral glands (D)</p> Signup and view all the answers

What occurs to the mesonephric kidney by the 12th week of gestation?

<p>It begins to regress and is replaced. (D)</p> Signup and view all the answers

In which region of the bladder is the neck located?

<p>Inferior region (A)</p> Signup and view all the answers

What mesodermal derivative contributes to the urogenital system?

<p>Mesonephric ducts (B)</p> Signup and view all the answers

Which structure assists in connecting the seminal vesicles with the ejaculatory ducts?

<p>Ductus deferens (C)</p> Signup and view all the answers

Which structure primarily produces oestradiol and inhibin in an ovarian follicle?

<p>Primordial follicle (C)</p> Signup and view all the answers

What is the primary function of the medulla in the ovary?

<p>Contain blood vessels (A)</p> Signup and view all the answers

At which stage of menstruation is the endometrial lining typically thickest?

<p>Luteal phase (D)</p> Signup and view all the answers

Which component is associated with the hilum area of the ovary?

<p>Medulla (A)</p> Signup and view all the answers

What characterizes the transition from primordial to pre-antral follicle?

<p>Increase in oocyte size and follicular cell number (C)</p> Signup and view all the answers

What structure is primarily responsible for the motility and transport of the oocyte to the uterus?

<p>Ampulla (A)</p> Signup and view all the answers

Which layer of the uterus is retained throughout the menstrual cycle?

<p>Basal layer (D)</p> Signup and view all the answers

How does the composition of the epithelium change from the infundibulum to the isthmus?

<p>More secretory and less motility cells (C)</p> Signup and view all the answers

What triggers the changes in the functional layer of the endometrium during the menstrual cycle?

<p>Changes in ovarian steroids (B)</p> Signup and view all the answers

During pregnancy, what occurs in the myometrium?

<p>Hypertrophy of smooth muscle (B)</p> Signup and view all the answers

What are the two main cell types found in the epithelium of the uterine tubes?

<p>Ciliated cells and secretory (peg) cells (A)</p> Signup and view all the answers

What characterizes the secretory phase of the uterine cycle?

<p>Secretion of hormones that support early pregnancy (C)</p> Signup and view all the answers

What is the main function of the muscularis externa in the reproductive organs?

<p>Facilitation of rhythmic contractions (C)</p> Signup and view all the answers

What is the main histological characteristic of the epithelium lining the cervix?

<p>Simple columnar epithelium (D)</p> Signup and view all the answers

What happens to cervical mucus consistency during the secretion of progesterone?

<p>It thickens and becomes sticky (A)</p> Signup and view all the answers

Which type of muscle primarily composes the cervix?

<p>Smooth muscle (A)</p> Signup and view all the answers

What is produced by the uterine glands to nourish the early fetus?

<p>Uterine milk (D)</p> Signup and view all the answers

What is the primary role of the rugae folds in the vagina?

<p>Allow for distention during intercourse and childbirth (D)</p> Signup and view all the answers

How does the high glycogen content in the vaginal epithelium primarily benefit the environment?

<p>Nourishes bacteria to produce lactic acid (D)</p> Signup and view all the answers

Which structure connects to the uterine tubes and is crucial for the transport of eggs?

<p>Fallopian tube (A)</p> Signup and view all the answers

Which anatomical structure secretes estrogen that affects the cervical mucus?

<p>Ovary (C)</p> Signup and view all the answers

What role does the tunica vaginalis play in the anatomy of the testes?

<p>Facilitates mobility and lubrication (A)</p> Signup and view all the answers

What physiological change occurs to uterine glands as the cellular components begin to degrade?

<p>They cease to produce uterine milk (D)</p> Signup and view all the answers

What is the primary function of the prostate's liquid secretion in seminal fluid?

<p>To break down the coagulum formed by seminal vesicle proteins (D)</p> Signup and view all the answers

Which of the following correctly describes the structure of the seminal vesicles?

<p>Paired coiled ducts exhibiting tall mucosal folds (A)</p> Signup and view all the answers

What role do the bulbourethral glands play in male reproductive anatomy?

<p>They provide a lubricant that neutralizes acidity (C)</p> Signup and view all the answers

Which statement correctly describes the anatomical significance of the ampulla in the male reproductive system?

<p>It is the area where the vas deferens becomes wider (D)</p> Signup and view all the answers

What is true about the time required for residual sperm elimination after a vasectomy?

<p>It requires at least 2 months or 30 ejaculates (D)</p> Signup and view all the answers

What is the primary role of granulosa cells in the dominant follicle?

<p>Enlarge and produce estradiol (C)</p> Signup and view all the answers

Which structure becomes the corpus luteum after follicle rupture?

<p>Granulosa cells (A)</p> Signup and view all the answers

What is the consequence if no pregnancy occurs after ovulation?

<p>Development of the corpus albicans (C)</p> Signup and view all the answers

In which ovarian follicle type is the antrum formed?

<p>Antral (secondary) follicle (A)</p> Signup and view all the answers

What is a significant feature of the cumulus oophorus in the dominant follicle?

<p>It surrounds the oocyte (B)</p> Signup and view all the answers

What physiological changes occur in the follicle before ovulation?

<p>Increased vascularization of theca cells (B)</p> Signup and view all the answers

Which cell type surrounds the entire follicle and is characterized as squamous-like?

<p>Thecal (stromal) cells (C)</p> Signup and view all the answers

What result occurs after the expansion of the antrum in antral follicles?

<p>Greater fluid secretion by granulosa cells (A)</p> Signup and view all the answers

Which layer is the zona pellucida secreted by?

<p>Oocyte (A)</p> Signup and view all the answers

What happens to the corpus luteum if a pregnancy does not occur?

<p>It transforms into the corpus albicans (D)</p> Signup and view all the answers

What is the primary role of Sertoli cells in the seminiferous tubules?

<p>Support and waste removal (B)</p> Signup and view all the answers

Which statement correctly describes the structure of the epididymis?

<p>Contains several layers of smooth muscle for transport (B)</p> Signup and view all the answers

What type of epithelium characterizes the efferent ductules?

<p>Pseudostratified columnar (D)</p> Signup and view all the answers

What is the significance of Leydig cells in the interstitial space of the seminiferous tubules?

<p>They secrete androgens (B)</p> Signup and view all the answers

Which structures drain sperm from the seminiferous tubules to the epididymis?

<p>Efferent ductules (C)</p> Signup and view all the answers

What functions are primarily associated with the vas deferens?

<p>Sperm transport and storage (B)</p> Signup and view all the answers

Which components are directly involved in sperm maturation within the reproductive system?

<p>Epididymis (A)</p> Signup and view all the answers

What type of muscle fibers are primarily present in the vas deferens?

<p>Smooth muscle (D)</p> Signup and view all the answers

How does the structure of the seminiferous tubules facilitate sperm production?

<p>Through tightly packed Sertoli and germ cells (A)</p> Signup and view all the answers

What is produced in the rete testis?

<p>Fluid for sperm transport (C)</p> Signup and view all the answers

Which histological feature distinguishes the principal cells in the epididymis?

<p>Tall structure with large microvilli (D)</p> Signup and view all the answers

What is a primary characteristic of spermatozoa compared to spermatogonia?

<p>Spermatozoa have a tail (B)</p> Signup and view all the answers

What type of cells are primarily involved in the structural framework of the seminiferous tubules?

<p>Fibroblasts (D)</p> Signup and view all the answers

Which structure acts as a barrier to protect developing germ cells in the seminiferous tubules?

<p>Sertoli cells (D)</p> Signup and view all the answers

What are the primary hormonal products of the primordial follicle?

<p>Estradiol and inhibin.</p> Signup and view all the answers

How does the structure of the ovary facilitate its function in reproductive biology?

<p>The ovary's cortex contains follicles for oocyte development, while the medulla supplies blood vessels.</p> Signup and view all the answers

What are the main differences between primordial and pre-antral follicles?

<p>Primordial follicles contain primary oocytes formed during fetal life, whereas pre-antral follicles emerge during puberty.</p> Signup and view all the answers

Identify the histological feature that distinguishes the endometrium across different menstrual stages.

<p>The thickness and structure of the endometrial lining vary, reflecting hormonal changes.</p> Signup and view all the answers

What role do the tunica albuginea and hilum play in the ovary's overall structure?

<p>The tunica albuginea provides structural support, while the hilum serves as the entry point for blood vessels and nerves.</p> Signup and view all the answers

What is the role of uterine milk in supporting the early fetus?

<p>Uterine milk nourishes the early fetus through diffusion, providing essential cellular components.</p> Signup and view all the answers

How does estrogen affect cervical mucus consistency?

<p>Estrogen makes cervical mucus fertile and watery, facilitating sperm transport.</p> Signup and view all the answers

What type of epithelium lines the vagina and why is it important?

<p>The vagina is lined by stratified squamous epithelium, which is important for protection and lubrication.</p> Signup and view all the answers

Describe the muscular composition surrounding the vagina.

<p>The vagina is surrounded by smooth muscle in the muscularis externa and voluntary muscle at the vaginal orifice.</p> Signup and view all the answers

What is the function of the cervix during pregnancy?

<p>The cervix maintains the pregnancy by holding the baby in place and regulating sperm transport.</p> Signup and view all the answers

How do the cervical glands contribute to reproductive health?

<p>Cervical glands secrete mucus that varies in consistency depending on hormonal influence.</p> Signup and view all the answers

What is the significance of rugae folds in the vagina?

<p>Rugae folds allow for distention during intercourse and childbirth.</p> Signup and view all the answers

What happens to the cellular components between uterine glands during early pregnancy?

<p>These cellular components start to degrade as part of the uterine secretions.</p> Signup and view all the answers

How does progesterone affect cervical mucus?

<p>Progesterone thickens cervical mucus, making it sticky and less hospitable to sperm.</p> Signup and view all the answers

What is the role of the tunica vaginalis surrounding the testis?

<p>The tunica vaginalis provides lubrication and mobility for the testis.</p> Signup and view all the answers

What is the primary function of the seminal vesicles in the male reproductive system?

<p>To produce seminal fluid that contains fructose and prostaglandins.</p> Signup and view all the answers

How do the prostate gland's mucosal folds differ from those of the seminal vesicles?

<p>The prostate gland has thicker mucosal folds compared to the seminal vesicles.</p> Signup and view all the answers

Why is a general anaesthetic not required for a vasectomy?

<p>Because the procedure can often be performed under local anaesthetic, minimizing patient discomfort.</p> Signup and view all the answers

What is the significance of the bulbourethral glands in male reproductive function?

<p>They produce pre-ejaculatory fluid that serves as an alkaline lubricant.</p> Signup and view all the answers

How long does it typically take to eliminate residual sperm after a vasectomy?

<p>It takes about 30 ejaculations or 2 months.</p> Signup and view all the answers

What is the role of ciliated and secretory cells in the oviduct?

<p>Ciliated cells aid in motility, while secretory cells nurture and transport the oocyte.</p> Signup and view all the answers

What significant changes occur in the endometrium during the menstrual cycle?

<p>The functional layer is sloughed off during menstruation, while the basal layer is retained.</p> Signup and view all the answers

How does the muscularis externa contribute to uterine functionality during pregnancy?

<p>It undergoes hypertrophy and rhythmic contractions, facilitating childbirth.</p> Signup and view all the answers

Describe the composition transition in the fallopian tube from the infundibulum to the isthmus.

<p>There are more secretory cells and less motility cells in the isthmus compared to the infundibulum.</p> Signup and view all the answers

What regulates the changes in the endometrial layers during the menstrual cycle?

<p>The changes are driven by variations in ovarian steroid hormones, mainly oestradiol and progesterone.</p> Signup and view all the answers

What happens to the myometrium during pregnancy, and why is this significant?

<p>The myometrium undergoes hypertrophy, which is significant for enabling strong contractions during labor.</p> Signup and view all the answers

What phases does the endometrial cycle consist of, and what is the main hormone involved during the secretory phase?

<p>The endometrial cycle includes the proliferative, secretory, and menstrual phases, with progesterone dominating the secretory phase.</p> Signup and view all the answers

How does the composition of the epithelium differ between the oviduct's ampulla and isthmus?

<p>The ampulla has more motility cells and secretory cells, while the isthmus has more secretory cells and fewer motility cells.</p> Signup and view all the answers

What is the function of Sertoli cells in seminiferous tubules?

<p>Sertoli cells support germ cells and remove waste during gametogenesis.</p> Signup and view all the answers

How do Leydig cells contribute to male reproductive health?

<p>Leydig cells secrete androgens, which maintain secondary sexual characteristics.</p> Signup and view all the answers

What is the primary role of the rete testis in sperm transport?

<p>The rete testis acts as a funneling network for transporting sperm from seminiferous tubules.</p> Signup and view all the answers

What are the two main functions of the epididymis?

<p>The epididymis is responsible for sperm maturation and transport.</p> Signup and view all the answers

What distinguishes the structure of the vas deferens from other tubular components?

<p>The vas deferens has three muscular layers: two longitudinal and one circular.</p> Signup and view all the answers

Describe the epithelium found in the efferent ductules.

<p>Efferent ductules contain pseudostratified columnar epithelium with both ciliated and absorptive cells.</p> Signup and view all the answers

Why is decapacitation important for sperm cell function?

<p>Decapacitation prevents sperm from fertilizing an egg until they reach the female reproductive tract.</p> Signup and view all the answers

Identify a structural component essential for maintaining the blood-testis barrier.

<p>Tight junctions between principal cells in the epididymis are essential for the blood-testis barrier.</p> Signup and view all the answers

What cellular changes occur in sperm during maturation in the epididymis?

<p>Sperm undergo metabolic changes, gain motility, and alter their cell membrane properties.</p> Signup and view all the answers

How does the tunica albuginea contribute to the testis structure?

<p>The tunica albuginea forms lobules that compartmentalize the seminiferous tubules.</p> Signup and view all the answers

Explain the significance of smooth muscle in the vas deferens.

<p>Smooth muscle in the vas deferens facilitates peristaltic contractions for sperm transport.</p> Signup and view all the answers

What type of cells primarily make up the principal structure of the epididymis?

<p>The principal cells of the epididymis are tall columnar cells with large microvilli.</p> Signup and view all the answers

What role do granulosa cells play in the antral follicle?

<p>Granulosa cells secrete fluid that forms the antrum in the follicle.</p> Signup and view all the answers

How does the structure of the epididymis aid in its function?

<p>The coiled structure of the epididymis increases the surface area for sperm maturation and absorption.</p> Signup and view all the answers

What is the developmental origin of the efferent ductules?

<p>Efferent ductules are derived from the mesonephric tubules.</p> Signup and view all the answers

How does a dominant follicle differ from others during the menstrual cycle?

<p>Only one dominant follicle matures per cycle while others undergo atresia.</p> Signup and view all the answers

What is the function of the corona radiata?

<p>The corona radiata consists of granulosa cells that surround the oocyte.</p> Signup and view all the answers

Why is the length of the vas deferens significant in male anatomy?

<p>The vas deferens is approximately 35 cm long, allowing for effective sperm storage before ejaculation.</p> Signup and view all the answers

What happens to the corpus luteum if pregnancy does not occur?

<p>It transforms into the corpus albicans after about 10-12 days.</p> Signup and view all the answers

What is the antrum and what stimulates its formation?

<p>The antrum is a fluid-filled cavity in the follicle formed under gonadotropin stimulation.</p> Signup and view all the answers

Describe the anatomical sections of the uterine tube.

<p>The uterine tube consists of three sections: infundibulum, ampulla, and isthmus.</p> Signup and view all the answers

What hormones are produced by the corpus luteum?

<p>The corpus luteum produces progesterone, oestradiol, and inhibin A.</p> Signup and view all the answers

What is the significance of the cumulus oophorus?

<p>Cumulus oophorus is a thickened layer of granulosa cells that encases the oocyte.</p> Signup and view all the answers

How do fimbriae contribute to the reproductive process?

<p>Fimbriae move closer to the ovary at ovulation, helping to capture the oocyte.</p> Signup and view all the answers

What is the importance of the zona pellucida?

<p>The zona pellucida is a glycoprotein layer secreted by the oocyte that protects it.</p> Signup and view all the answers

What factors contribute to the importance of lactation for both newborn survival and maternal health?

<p>Lactation supports newborn growth and immunity while providing health benefits to mothers, like improved birth spacing and reduced cancer risk.</p> Signup and view all the answers

How does the structure of mammary gland lobules relate to their function in milk production?

<p>Mammary gland lobules contain alveoli that secrete milk, and their arrangement allows efficient transport through lactiferous ducts to the nipple.</p> Signup and view all the answers

What hormonal controls are involved in the milk ejection reflex during lactation?

<p>Oxytocin triggers the milk ejection reflex by contracting myoepithelial cells around the alveoli, facilitating milk flow.</p> Signup and view all the answers

Describe the changes that occur in breast anatomy during pregnancy and lactation.

<p>During pregnancy, breast tissue proliferates and increases in vascularity; after childbirth, the glands mature for milk production.</p> Signup and view all the answers

How does the development of mammary glands differ across the life course, particularly during puberty and after childbirth?

<p>Mammary gland development initiates during puberty with duct elongation and branching, followed by significant growth and differentiation during pregnancy.</p> Signup and view all the answers

What structures primarily make up inactive breasts?

<p>Inactive breasts mainly consist of ducts and connective tissue, with minimal gland development.</p> Signup and view all the answers

What is the main function of sebaceous glands in the nipple area?

<p>They secrete sebum to protect the epidermal surface from chafing and cracking during nursing.</p> Signup and view all the answers

What is the lymphatic drainage pattern for the medial side of the breasts?

<p>The medial side of the breasts drains into the parasternal lymph nodes.</p> Signup and view all the answers

During which state of breast histology does lobulo-alveolar development primarily occur?

<p>Lactating state.</p> Signup and view all the answers

Identify the arterial supply to the breasts from lateral and medial sides.

<p>The lateral arterial supply to the breasts comes from branches of the axillary artery, while the medial supply comes from branches of the internal thoracic artery.</p> Signup and view all the answers

What role do myoepithelial cells play in breast tissue?

<p>They are contractile cells that help in the expulsion of milk during lactation.</p> Signup and view all the answers

Which spinal nerves innervate the breast and nipple, respectively?

<p>The breast is innervated by the 2nd to 6th intercostal nerves, and the nipple is specifically innervated by the 4th intercostal nerve.</p> Signup and view all the answers

How much glandular tissue is found in the 30mm radius surrounding the base of the nipple?

<p>Approximately 65% of the glandular tissue is located within a 30mm radius of the nipple's base.</p> Signup and view all the answers

What changes occur in the breast tissue of non-pregnant women during the menstrual cycle?

<p>There are cyclic changes due to estrogen and progesterone stimulation, leading to some duct growth and limited lobulo-alveolar development.</p> Signup and view all the answers

What is the effect of smooth muscle bundles in the nipple area upon stimulation?

<p>They contract in response to cold, touch, and sexual arousal.</p> Signup and view all the answers

What embryological layer gives rise to breast tissue?

<p>Ectoderm.</p> Signup and view all the answers

At what gestational week do breast structures first become visible?

<p>Approximately 4 weeks.</p> Signup and view all the answers

What phenomenon may occur at birth due to maternal hormone exposure?

<p>'Witches milk' secretion.</p> Signup and view all the answers

Describe the significance of the 'milk line' in breast development.

<p>It marks the paired epidermal thickenings along which breasts develop.</p> Signup and view all the answers

What physical changes characterize the breast during puberty?

<p>Increase in breast size and proliferation of ducts.</p> Signup and view all the answers

What hormonal changes trigger the secretory activation of lactogenesis after birth?

<p>A decrease in progesterone and oestrogen due to parturition triggers the secretory activation.</p> Signup and view all the answers

How does nipple stimulation contribute to milk production and ejection?

<p>Nipple stimulation activates spinal nerves, leading to the secretion of prolactin for milk synthesis and oxytocin for milk ejection.</p> Signup and view all the answers

What process occurs in breast tissue after weaning?

<p>Involution occurs, characterized by mechanical atrophy, loss of epithelial cells, and replacement with stromal and fat tissue.</p> Signup and view all the answers

Describe the changes in milk volume from day 2 to day 4 post-partum.

<p>Milk volume increases from 50ml per day on day 2 to 500ml per day on day 4.</p> Signup and view all the answers

What hormonal factors are involved in the proliferation of breast tissue during puberty?

<p>Oestrogen, growth hormone, and adrenal steroids facilitate the proliferation and development of breast tissue.</p> Signup and view all the answers

What causes lactational amenorrhoea during breastfeeding?

<p>Lactational amenorrhoea is caused by the erratic release of GnRH and LH due to prolonged breastfeeding, inhibiting ovarian activity.</p> Signup and view all the answers

How does the suckling stimulus affect GnRH secretion during lactation?

<p>The suckling stimulus leads to erratic release of GnRH, disrupting the normal pulse frequency and inhibiting ovulation.</p> Signup and view all the answers

What hormonal changes occur after birth that influence ovarian activity?

<p>After birth, there is a decline in estrogen and progesterone, leading to the initiation of pulsatile GnRH and LH secretion.</p> Signup and view all the answers

Describe the relationship between hormonal levels during pregnancy and GnRH secretion.

<p>High levels of estrogen and progesterone during pregnancy suppress GnRH secretion, which in turn inhibits follicular development and ovulation.</p> Signup and view all the answers

What is the significance of myoepithelial cell contraction in lactation?

<p>Contraction of myoepithelial cells around alveoli during lactation aids in the expulsion of milk from the alveoli into the lactiferous ducts.</p> Signup and view all the answers

What is the primary function of the lactiferous ducts in breast anatomy?

<p>To transport milk from the lobules to the nipple (D)</p> Signup and view all the answers

Which statement accurately describes the composition of inactive breasts?

<p>Inactive breasts mainly consist of adipose tissue and glandular ducts. (C)</p> Signup and view all the answers

Which arteries primarily supply the medial aspects of the breast?

<p>Branches from the internal thoracic artery (B)</p> Signup and view all the answers

What percentage of glandular breast tissue is located within a 30mm radius of the nipple?

<p>65% (B)</p> Signup and view all the answers

Where does the majority of lymphatic drainage of the breast occur?

<p>Into the axillary nodes (C)</p> Signup and view all the answers

What physiological mechanism is primarily involved in suppressing ovarian activity during breastfeeding?

<p>Erratic GnRH release (A)</p> Signup and view all the answers

Which factor chiefly influences the duration of lactational amenorrhea?

<p>Duration and intensity of breastfeeding (B)</p> Signup and view all the answers

During pregnancy, what hormonal changes contribute to the inhibition of follicular development?

<p>Decrease in gonadotropin-releasing hormone (A)</p> Signup and view all the answers

What triggers the release of prolactin during lactation?

<p>Strength of the sucking stimulus (B)</p> Signup and view all the answers

What is the typical timeframe for ovulation to occur in a non-breastfeeding woman after childbirth?

<p>Within 2-3 weeks (D)</p> Signup and view all the answers

What type of epithelial tissue is found in the cross section of the nipple?

<p>Stratified squamous epithelium (D)</p> Signup and view all the answers

Which structure is responsible for secreting sebum on the epidermal surface of the nipple?

<p>Sebaceous glands (C)</p> Signup and view all the answers

What change occurs in the breast during the lactating state compared to the inactive state?

<p>Less connective tissue (D)</p> Signup and view all the answers

What physiological response do myoepithelial cells in the breast have?

<p>Contraction in response to stimuli (C)</p> Signup and view all the answers

What is a noteworthy feature of lactiferous ducts within the breast structure?

<p>Transport milk from lobules to the nipple (D)</p> Signup and view all the answers

What is the main functional significance of lactation in mammals?

<p>It aids in the immediate survival and growth of the newborn. (B)</p> Signup and view all the answers

Which anatomical structure primarily supports the mammary glands in the human breast?

<p>Suspensory ligaments (A)</p> Signup and view all the answers

During which stage of life does the breast undergo the most significant developmental changes?

<p>Pregnancy and lactation (C)</p> Signup and view all the answers

What primary hormonal mechanism regulates the milk ejection reflex during lactation?

<p>Oxytocin secretion (C)</p> Signup and view all the answers

Which of the following factors contributes to the overall health benefits of lactation for mothers?

<p>Reduced risk of osteoporosis (B)</p> Signup and view all the answers

What hormonal changes primarily trigger lactogenesis following birth?

<p>Decreased levels of progesterone and oestrogen (C)</p> Signup and view all the answers

What structure is primarily responsible for the ejection of milk during lactation?

<p>Oxytocin (B)</p> Signup and view all the answers

During involution, which process primarily leads to the structural changes observed in breast tissue?

<p>Apoptosis of epithelial cells (A)</p> Signup and view all the answers

What is the maximum milk yield typically achieved during lactation?

<p>850 ml per day or more (A)</p> Signup and view all the answers

What is the main factor contributing to the maintenance of maximal milk yield during lactation?

<p>Removal of milk due to infant demand (A)</p> Signup and view all the answers

At what embryological stage do paired epidermal thickenings, known as the 'milk line', become visible?

<p>Approximately 4 weeks of gestation (A)</p> Signup and view all the answers

Which stage of pubertal breast development is characterized by the formation of a secondary mound above the level of the breast?

<p>Areolar and papilla secondary mound stage (D)</p> Signup and view all the answers

What is the term used for the minimal duct development and secretory activity observed at birth, often referred to as 'witches milk'?

<p>Colostrum (A)</p> Signup and view all the answers

What does the increase in breast size during puberty primarily indicate?

<p>Fat accumulation and duct proliferation (C)</p> Signup and view all the answers

What percentage of females has a supernumerary breast or nipple as a result of embryological anomalies?

<p>1% (D)</p> Signup and view all the answers

What do primordial germ cells differentiate into during urogenital development?

<p>Gametes (C)</p> Signup and view all the answers

Which statement best describes the gonadal migration during development?

<p>Gonads migrate from an initial position to their adult anatomical location (D)</p> Signup and view all the answers

What aspect is crucial for understanding Disorders of Sexual Development?

<p>Morphological changes during urogenital development (C)</p> Signup and view all the answers

What is the primary function of somatic support cells in the urogenital ridge?

<p>To provide structural integrity to developing organs (D)</p> Signup and view all the answers

During the development of the external genitalia, which of the following relationships is particularly significant?

<p>The interaction between mesonephric ducts and gonads (C)</p> Signup and view all the answers

What is the primary outcome of the elongation of the genital tubercle in males?

<p>Formation of the phallus (B)</p> Signup and view all the answers

What role does the gubernaculum play in the descent of the gonads?

<p>Anchors the testis to the scrotum (B)</p> Signup and view all the answers

What structures are formed as remnants of the paramesonephric duct in males?

<p>Cervix and uterus (D)</p> Signup and view all the answers

What is the result of the urethral folds closing in males during development?

<p>Formation of the penile urethra (A)</p> Signup and view all the answers

How does the sperm viability relate to scrotal temperature regulation?

<p>Lower temperatures in the scrotum improve viability (C)</p> Signup and view all the answers

What anatomical feature is created as the ovaries descend and the gubernaculum is involved?

<p>Round ligament of the uterus (D)</p> Signup and view all the answers

Which condition can result from the retention of the paramesonephric duct in males?

<p>Persistent Müllerian Duct Syndrome (B)</p> Signup and view all the answers

What ultimately completes cloacal septation in female development?

<p>By week 12 (D)</p> Signup and view all the answers

What initiates the differentiation of Sertoli cells in male gonadal development?

<p>SRY expression in somatic support cells (D)</p> Signup and view all the answers

What hormone do Leydig cells secrete during early male development?

<p>Testosterone under influence of hCG (B)</p> Signup and view all the answers

Which structures are derived from the para-mesonephric duct in females?

<p>Uterine tubes and uterus (B)</p> Signup and view all the answers

What happens to the mesonephric duct in females during development?

<p>It becomes completely regressed (A)</p> Signup and view all the answers

What is the role of the gubernaculum during gonadal descent?

<p>It draws the gonad caudally (C)</p> Signup and view all the answers

Which cells are responsible for producing Anti-Mullerian Hormone (AMH) during male development?

<p>Sertoli cells (A)</p> Signup and view all the answers

How do the male and female reproductive ducts differ in terms of the paramesonephric duct?

<p>It completely disappears in males (A)</p> Signup and view all the answers

What critical developmental stage occurs around the 6-week mark in both sexes?

<p>Migration of PGC from yolk sac to mesenchyme (B)</p> Signup and view all the answers

During which weeks do morphological differences emerge between male and female gonads?

<p>10-13 weeks (D)</p> Signup and view all the answers

What happens to the gonads during the descent process in males?

<p>They are drawn through the inguinal canal (D)</p> Signup and view all the answers

What are primordial germ cells (PGC) and what role do they play in gonadal development?

<p>Primordial germ cells (PGC) are the precursors to gametes, playing a crucial role in the formation of gametes during gonadal development.</p> Signup and view all the answers

How do somatic support cells contribute to sexual dimorphism in the urogenital tract?

<p>Somatic support cells differentiate in response to hormonal signals, contributing to the formation of male or female reproductive structures, hence establishing sexual dimorphism.</p> Signup and view all the answers

Explain the significance of tubular migrations during urogenital development.

<p>Tubular migrations are significant as they direct the proper formation and positioning of reproductive tracts, ensuring functional anatomical structures in adults.</p> Signup and view all the answers

How can disorders of sexual development arise from morphological variations in urogenital development?

<p>Disorders of sexual development can arise from genetic or environmental disruptions during the developmental phase of the urogenital tracts, leading to atypical morphology.</p> Signup and view all the answers

What role do the developed gonads play in the formation of adult reproductive anatomy?

<p>The developed gonads produce hormones that drive the differentiation and development of adult reproductive anatomy, influencing characteristics like external genitalia.</p> Signup and view all the answers

What results from the failure of the paramesonephric duct to disintegrate in males?

<p>Persistent Müllerian Duct Syndrome arises, resulting in an XY individual with testes who also has female reproductive structures.</p> Signup and view all the answers

Describe the anatomical significance of the gubernaculum in females.

<p>The gubernaculum assists in guiding the descent of the ovaries and forms the Ligament of Ovary and the Round ligament.</p> Signup and view all the answers

How does the scrotum regulate temperature for sperm viability?

<p>The scrotum uses the Dartos muscle for contraction and a counter-current heat exchange mechanism to maintain optimal temperatures.</p> Signup and view all the answers

What role does the genital tubercle play in sexual differentiation?

<p>The genital tubercle elongates in males to form the phallus, while it remains short in females, leading to the formation of the clitoris.</p> Signup and view all the answers

At what week does cloacal septation complete, and what does it result in for females?

<p>Cloacal septation is completed by week 12, resulting in separate urethral, vaginal, and anal openings in females.</p> Signup and view all the answers

What causes the developmental differences in external genitalia between sexes before week 9?

<p>Before week 9, external genitalia remain indifferent, but testosterone in males drives elongation of the genital tubercle and fusion of urethral folds.</p> Signup and view all the answers

Explain the significance of the broad ligament in female reproductive anatomy.

<p>The broad ligament is a mesentery that supports the ovaries and assists in the positioning of the uterus and uterine tubes.</p> Signup and view all the answers

What anatomical feature results from the gubernaculum dragging the gonad through the inguinal canal?

<p>The Round ligament, or Lig. Teres, is formed as a remnant of the gubernaculum dragging the ovary through the inguinal canal.</p> Signup and view all the answers

What initiates the differentiation of somatic support cells into Sertoli cells in males?

<p>SRY gene expression.</p> Signup and view all the answers

How do Leydig cells differentiate and what hormone do they secrete?

<p>Leydig cells differentiate from mesenchyme and secrete testosterone.</p> Signup and view all the answers

What is the significance of Sertoli cells producing Anti-Mullerian Hormone (AMH)?

<p>AMH suppresses the development of the paramesonephric duct system.</p> Signup and view all the answers

In females, what does the para-mesonephric (Müllerian) duct give rise to?

<p>Uterine tubes, uterus, and cervix.</p> Signup and view all the answers

What happens to the mesonephric duct in female development?

<p>Mesonephric duct degenerates completely.</p> Signup and view all the answers

What is the role of the gubernaculum in the descent of the gonads?

<p>The gubernaculum draws the gonad caudally as the fetus grows.</p> Signup and view all the answers

How does the reinforcing connection from mesonephric ducts change during male development?

<p>It connects to the bladder, replacing the urinary function.</p> Signup and view all the answers

What is formed when the paramesonephric ducts fuse caudally in females?

<p>The uterus and cervix.</p> Signup and view all the answers

What role does the mesonephros serve during early gestation in both sexes?

<p>It coexists with the developing gonads and ducts.</p> Signup and view all the answers

At what stage do morphological differences between male and female gonads become apparent?

<p>Between 10-13 weeks of gestation.</p> Signup and view all the answers

What is the role of Buck's fascia in the male anatomy?

<p>Buck's fascia serves as the deep penile fascia that covers and supports the male erectile tissues.</p> Signup and view all the answers

How does Scarpa's fascia relate to Colles' fascia?

<p>Scarpa's fascia is continuous with Colles' fascia, linking the superficial abdominal wall with the superficial perineal region.</p> Signup and view all the answers

What structures create the compartments within the deep perineal fascia?

<p>The deep perineal fascia contains the male erectile tissues and delineates spaces for the urogenital diaphragm and associated structures.</p> Signup and view all the answers

Describe the anatomical significance of the perineal body.

<p>The perineal body serves as a central structure that connects various perineal muscles and fascia, providing structural support.</p> Signup and view all the answers

What distinguishes the perineal structure in placental mammals from that in other tetrapods?

<p>Placental mammals septate their cloaca, leading to a different structural plan for the perineum compared to other tetrapods.</p> Signup and view all the answers

Identify the layers included in the evolution of the perineum and their significance.

<p>The layers include subcutaneous, external, internal, and transverse, which reflect the evolution of muscle organization in mammals.</p> Signup and view all the answers

Explain how the deep pouch and superficial pouch of the perineum differ.

<p>The deep pouch contains the urogenital diaphragm and deeper structures, while the superficial pouch houses external genitalia and associated muscles.</p> Signup and view all the answers

What anatomical function does the Cutaneous Trunci muscle serve in mammals?

<p>The Cutaneous Trunci muscle is responsible for voluntary skin contraction and contributes to the overall musculature of the body wall.</p> Signup and view all the answers

What is the primary muscle forming the superficial component of the external anal sphincter?

<p>Superficial external anal sphincter.</p> Signup and view all the answers

Name the erectile tissues present in the male superficial pouch.

<p>Corpus-spongiosum and Corpus-cavernosum.</p> Signup and view all the answers

What two muscles support the erectile tissues in the female superficial pouch?

<p>Bulbo-spongiosus and Ischio-cavernosus.</p> Signup and view all the answers

What is the role of the perineal membrane in the urogenital diaphragm?

<p>It forms the inferior border of the deep pouch containing pelvic viscera.</p> Signup and view all the answers

What are the main features and boundaries of the perineum?

<p>The perineum is divided into the anal triangle and the urogenital triangle, featuring structures such as the anococcygeal raphe and perineal body.</p> Signup and view all the answers

What is the sphincter muscle that is exclusive to females within the urogenital triangle?

<p>Compressor urethrae and Sphincter urethrovaginalis.</p> Signup and view all the answers

Identify the space associated with the subcutaneous body wall in the perineum.

<p>Ischiorectal / Ischioanal fossa.</p> Signup and view all the answers

Describe the role of the pudendal nerve in the perineum.

<p>The pudendal nerve provides sensory innervation to the skin of the anal and urogenital triangles and motor supply to voluntary muscles in the perineal region.</p> Signup and view all the answers

What anatomical structures are found in the superficial pouch of females that are homologous to male structures?

<p>Bulb of the vestibule and Greater vestibular gland.</p> Signup and view all the answers

Identify the structure that separates the anal triangle from the urogenital triangle.

<p>The perineal membrane separates the anal triangle and the urogenital triangle.</p> Signup and view all the answers

What are the two angular configurations of the perineum and their orientations?

<p>The perineum is divided into an open anal triangle and a closed urogenital triangle, arranged in a roughly diamond shape.</p> Signup and view all the answers

What distinguishes the external urethral sphincter found in the urogenital diaphragm?

<p>It is a critical muscle for continence in both genders.</p> Signup and view all the answers

How is the perineal body defined and what is its significance?

<p>The perineal body is a fibromuscular structure located between the anal and urogenital triangles, serving as an anchor for pelvic floor muscles.</p> Signup and view all the answers

Which branches arise from the pudendal nerve, and what areas do they supply?

<p>The branches of the pudendal nerve include the inferior rectal nerve, perineal nerve, and dorsal nerve of the penis or clitoris, supplying the anal and urogenital regions.</p> Signup and view all the answers

What is the anatomical significance of the pudendal canal?

<p>The pudendal canal is a fibrous canal located within the internal obturator fascia that houses the pudendal vessels and nerve, ensuring their protection as they travel.</p> Signup and view all the answers

Explain the relationship between the perineum and erectile tissues.

<p>The perineum contains erectile tissues that are essential for sexual function, providing structural support during erection.</p> Signup and view all the answers

What is the primary function of the deep transverse perineal muscle?

<p>Its primary function is to stabilize the perineal body.</p> Signup and view all the answers

How does the external urethral sphincter function differently in males and females?

<p>In both sexes, it compresses the urethra but relaxes during micturition.</p> Signup and view all the answers

Where does the deep external anal sphincter insert, and what is its main role?

<p>It inserts into the perineal body and anococcygeal body, closing the anal canal.</p> Signup and view all the answers

What accessory function does the compressor urethrae serve in the female anatomy?

<p>It acts as an accessory urethral sphincter.</p> Signup and view all the answers

What anatomical origin is common to the deep transverse perineal muscle?

<p>It originates from the ischial ramus.</p> Signup and view all the answers

What are the main muscle components of the pelvic floor and their functions?

<p>The main muscle components include Puborectalis, Pubococcygeus, Iliococcygeus, and Ischiococcygeus, which support the pelvic viscera and reinforce the rectoanal and vaginal angles.</p> Signup and view all the answers

Describe the origin and insertion of the Ischiococcygeus muscle.

<p>The Ischiococcygeus originates from the coccyx and lower sacrum and inserts at the ischial spine and sacrospinous ligament.</p> Signup and view all the answers

What is the significance of the puborectalis muscle in the human body?

<p>The puborectalis muscle is significant for maintaining the rectoanal angle and plays a role in reinforcing the anal sphincter.</p> Signup and view all the answers

How do the pelvic floor muscles differ in their roles between sexes?

<p>While pelvic floor muscles support visceral organs in both sexes, they also serve gender-specific functions, such as supporting the vaginal canal in females and the prostate in males.</p> Signup and view all the answers

Explain the relationship between the pelvic floor muscles and the pelvic viscera.

<p>The pelvic floor muscles support the pelvic viscera by providing structural integrity and maintaining proper positioning of organs within the pelvis.</p> Signup and view all the answers

What components make up the pelvic floor muscles and their primary functions?

<p>The pelvic floor muscles consist of the levator ani and ischiococcygeus. They maintain pelvic organ support and facilitate processes like lifting the anal canal.</p> Signup and view all the answers

What is the role of the bulbourethral gland in male anatomy?

<p>The bulbourethral gland secretes pre-ejaculatory fluid that helps lubricate the urethra. It also neutralizes acidity in the urethra.</p> Signup and view all the answers

Describe the function of the bulbospongiosus muscle in males.

<p>The bulbospongiosus muscle helps to remove urine from the urethra and contributes to pulsatile ejaculation of semen. It performs rhythmic contractions during ejaculation.</p> Signup and view all the answers

What are the key differences between the superficial and deep pouches in males?

<p>The deep pouch contains the urogenital diaphragm muscles and the bulbourethral gland, while the superficial pouch contains erectile tissues and muscles. The superficial pouch is located between the perineal membrane and Colles' fascia.</p> Signup and view all the answers

What muscles support the urogenital diaphragm and their specific contributions?

<p>The urogenital diaphragm is supported by the deep pouch muscles, including the external urethral sphincter. They contribute to urinary continence and pelvic floor stability.</p> Signup and view all the answers

How does the function of the ischiocavernosus muscle differ between males and females?

<p>In males, the ischiocavernosus muscle helps direct blood from the crura to the body of the penis, while in females, it performs a similar function for the glans of the clitoris. Both aid in sexual arousal and erection.</p> Signup and view all the answers

What ligaments contribute to the pelvic floor's structural integrity?

<p>The sacrospinous ligament and the sacrotuberous ligament provide support to the pelvic floor, anchoring muscles and fascia. They play a vital role in maintaining pelvic stability.</p> Signup and view all the answers

What are the roles of the greater vestibular gland in female anatomy?

<p>The greater vestibular gland, homologous to the bulbourethral gland, secretes mucus for vaginal lubrication during sexual arousal. It helps in maintaining vaginal health.</p> Signup and view all the answers

What is the primary function of the deep transverse perineal muscle?

<p>Stabilises the perineal body (C)</p> Signup and view all the answers

Which structure is the origin of the deep external anal sphincter muscle?

<p>Superior aspect of the anal canal (C)</p> Signup and view all the answers

In females, what is the role of the compressor urethrae muscle?

<p>Accessory urethral sphincter (C)</p> Signup and view all the answers

What is the insertion point for the deep transverse perineal muscle?

<p>Perineal body (D)</p> Signup and view all the answers

Which origin corresponds to the external urethral sphincter muscle?

<p>Ischiopubic ramus (A)</p> Signup and view all the answers

What is the primary function of the iliococcygeus muscle?

<p>Supports pelvic organs and assists in pelvic floor strength (C)</p> Signup and view all the answers

Where does the pubococcygeus muscle insert?

<p>Ischial spine and perineal body (A)</p> Signup and view all the answers

What anatomical structure does the puborectalis muscle connect?

<p>Perineal body (C)</p> Signup and view all the answers

Which muscle helps maintain the rectoanal angle?

<p>Puborectalis (D)</p> Signup and view all the answers

What common function do the ischiococcygeus and iliococcygeus muscles share?

<p>Support the pelvic floor and viscera (A)</p> Signup and view all the answers

What is the role of Buck's fascia in male anatomy?

<p>Investing fascia for deep penile structures (D)</p> Signup and view all the answers

What muscle forms the superficial component of the external anal sphincter?

<p>Superficial external anal sphincter (D)</p> Signup and view all the answers

Which fascia is known as the superficial perineal fascia?

<p>Colle’s fascia (B)</p> Signup and view all the answers

Which anatomical structures are supported by the muscles within the urogenital diaphragm?

<p>Pelvic viscera and the pelvic floor (C)</p> Signup and view all the answers

How are the layers of the perineum categorized in mammals?

<p>As a continuum with four defined layers (B)</p> Signup and view all the answers

What extra contents are found in the male superficial pouch?

<p>Testes and spermatic cord (C)</p> Signup and view all the answers

What is a significant anatomical feature of Scarpa’s fascia?

<p>It connects the abdominal wall to the perineum. (D)</p> Signup and view all the answers

What structural component helps define the boundaries of the perineum?

<p>Perineal body (B)</p> Signup and view all the answers

Which triangle of the perineum is open and primarily associated with the anal region?

<p>Anal triangle (B)</p> Signup and view all the answers

Which structure is NOT involved in creating compartments in the perineum?

<p>Scarpa’s fascia (A)</p> Signup and view all the answers

What layer forms the inferior border of the deep pouch in the perineum?

<p>Perineal membrane (B)</p> Signup and view all the answers

What evolutionary adaptation is observed in placental mammals regarding the perineum?

<p>Formation of distinct cloacal compartments (D)</p> Signup and view all the answers

In females, which structures are considered homologous to the male erectile tissues?

<p>Clitoris and bulb of the vestibule (D)</p> Signup and view all the answers

Which nerve is responsible for the sensory and motor functions of the perineum?

<p>Pudendal nerve (C)</p> Signup and view all the answers

What significant feature of the perineum serves as an attachment point for various structures?

<p>Anococcygeal raphe (A)</p> Signup and view all the answers

What defines the lateral wall of the ischiorectal fossa in the perineum?

<p>Obturator internus and ischiopubic rami (A)</p> Signup and view all the answers

Which muscle layer is part of the urogenital diaphragm?

<p>Deep external anal sphincter (A)</p> Signup and view all the answers

Which structure is associated with the superficial pouch of the perineum?

<p>Bulb of vestibule (A)</p> Signup and view all the answers

Which muscle is significant for forming the median raphe in both males and females?

<p>Bulbo-spongiosus (A)</p> Signup and view all the answers

Which of the following statements about the perineal body is accurate?

<p>It acts as an anchor point for multiple musculature layers. (A)</p> Signup and view all the answers

What is the role of the perineal membrane within the structure of the perineum?

<p>Forms the floor of the deep pouch (D)</p> Signup and view all the answers

What muscle is responsible for maintaining the recto-anal angle?

<p>Puborectalis (B)</p> Signup and view all the answers

What characterizes the third layer of the perineum?

<p>Includes skeletal muscles of the urogenital diaphragm (D)</p> Signup and view all the answers

Which of the following branches of the pudendal nerve supplies the skin of the anal triangle?

<p>Inferior rectal nerve (D)</p> Signup and view all the answers

Which structure is part of the deep pouch in males?

<p>Bulbourethral gland (B)</p> Signup and view all the answers

What anatomical feature primarily assists in identifying the female urethra's location in the urogenital triangle?

<p>Vulva (B)</p> Signup and view all the answers

What is the primary function of the ischiocavernosus muscle in males?

<p>Draw blood into the body of the penis (C)</p> Signup and view all the answers

Which muscle assists in lifting the anal canal, vagina, or prostate?

<p>Pubococcygeus (D)</p> Signup and view all the answers

Which structure serves as the roof of the deep pouch?

<p>Fascia on top of the muscles (D)</p> Signup and view all the answers

What is the primary role of the bulbospongiosus muscle in females?

<p>Blood transfer from the body of clitoris to the glans (A)</p> Signup and view all the answers

Which component is not found in the male superficial pouch?

<p>Bulbourethral gland (A)</p> Signup and view all the answers

Which muscle's origin includes the perineal body and median raphe?

<p>Bulbospongiosus (B)</p> Signup and view all the answers

Which ligament is responsible for forming the lesser sciatic foramen along with the sacrotuberous ligament?

<p>Sacrospinous ligament (C)</p> Signup and view all the answers

What does the obturator nerve primarily innervate within the pelvic region?

<p>Adductor muscles of the thigh (B)</p> Signup and view all the answers

Which structure does NOT pass through the greater sciatic foramen?

<p>Internal pudendal artery (A)</p> Signup and view all the answers

The obturator fascia is associated with which of the following muscles?

<p>Obturator externus (A)</p> Signup and view all the answers

What is the primary function of the obturator foramen?

<p>Provide a passage for blood vessels and nerves (C)</p> Signup and view all the answers

Which structure passes through the lesser sciatic foramen entering the pelvis?

<p>Pudendal nerve &amp; vessels (D)</p> Signup and view all the answers

What type of cartilage primarily connects the pubic bones in the pubic symphysis?

<p>Fibrocartilage (B)</p> Signup and view all the answers

Which ligaments reinforce the structure between the pubic bones?

<p>Superior pubic ligament and inferior (Arcuate) ligament (D)</p> Signup and view all the answers

How does the structure of the pelvic diaphragm contribute to the pelvic outlet?

<p>It provides a gateway that supports pelvic viscera. (C)</p> Signup and view all the answers

What is the primary mechanical link between the limbs at the pubic symphysis?

<p>Anterior mechanical link (C)</p> Signup and view all the answers

What primarily forms the walls of the true pelvis below the pelvic brim?

<p>Sacrum, pubis, and ischium (D)</p> Signup and view all the answers

Which structure is located at the inferior opening of the pelvic cavity?

<p>Pelvic outlet (D)</p> Signup and view all the answers

What anatomical feature connects the os coxa to the vertebrae?

<p>Girdle for lower limb attachment (B)</p> Signup and view all the answers

Which line is not a part of the pelvic brim?

<p>Sacrotuberous line (A)</p> Signup and view all the answers

Which of the following is primarily involved in transmitting ground reaction forces in the pelvis?

<p>Stiff bones (B)</p> Signup and view all the answers

The true pelvis includes which of the following characteristics?

<p>Forms the bony walls of pelvic cavity (B)</p> Signup and view all the answers

What are the ischial tuberosities primarily referred to in the context of the pelvic cavity?

<p>Bump-like structures (D)</p> Signup and view all the answers

Which of the following correctly identifies the structures below the pelvic brim?

<p>Sacrum, ischium, and pubis (C)</p> Signup and view all the answers

What are the three bones that fuse to form the os coxa?

<p>Ilium, ischium, pubis (C)</p> Signup and view all the answers

How does pelvic sexual dimorphism manifest in the human pelvis?

<p>Through differences in pelvic basin width and shape (B)</p> Signup and view all the answers

What is the primary biomechanical function of the human pelvis?

<p>To serve as a basin for pelvic viscera (A)</p> Signup and view all the answers

Which structure forms the base of the pelvic girdle?

<p>Sacrum (B)</p> Signup and view all the answers

What evolutionary pressure significantly influenced the structure of the human pelvis?

<p>Adaptation for bipedal locomotion (B)</p> Signup and view all the answers

What unique feature distinguishes the female pelvis from the male pelvis?

<p>Wider pelvic inlet (B)</p> Signup and view all the answers

Which aspect of the pelvic function is directly related to parturition?

<p>Shape and size of the pelvic basin (A)</p> Signup and view all the answers

Which of the following statements best reflects a challenge the female pelvis faces during parturition?

<p>Decreased distance between the pelvic inlet and outlet (B)</p> Signup and view all the answers

What anatomical structure assists in resisting the anterior slip of the lumbar vertebrae?

<p>Iliolumbar ligament (B)</p> Signup and view all the answers

What is the typical angle of the sacroiliac joint in females?

<p>80 degrees (B)</p> Signup and view all the answers

Which structures primarily resist anterior pelvic rotation?

<p>Dorsal interosseous SI ligaments (B)</p> Signup and view all the answers

What is the approximate vertical center of gravity (CoG) in relation to the sacrum?

<p>S2 (B)</p> Signup and view all the answers

Which ligament plays a critical role in resisting the tendency of the sacrum to rotate forwards relative to the ilium?

<p>Sacrotuberous ligament (A)</p> Signup and view all the answers

At what angle is the lumbosacral joint typically oriented?

<p>60 degrees (A)</p> Signup and view all the answers

What mechanism primarily contributes to the anterior slipping tendency of the lumbar region?

<p>Force on lumbar (A)</p> Signup and view all the answers

Which additional ligaments alongside the dorsal interosseous SI ligaments help resist anterior pelvic rotation?

<p>Sacrospinous and sacrotuberous ligaments (C)</p> Signup and view all the answers

What is one of the primary adaptations of the human pelvis for bipedalism?

<p>Broader sacrum (D)</p> Signup and view all the answers

How does the structure of the ilial neck contribute to bipedal locomotion?

<p>It is shortened and deepened to raise the center of gravity (D)</p> Signup and view all the answers

What impact do ischial spines have on the pelvis during pregnancy?

<p>They enhance bipedal efficiency (C)</p> Signup and view all the answers

Why is trunk inertia crucial for bipedal locomotion?

<p>It must balance lower limb inertia (C)</p> Signup and view all the answers

What role do abdominal oblique muscles play in bipedal locomotion?

<p>They store elastic energy during walking (C)</p> Signup and view all the answers

What evolutionary pressure is greater than parturition in relation to pelvic adaptations?

<p>Pre-birth work capacity (B)</p> Signup and view all the answers

What characteristic of the acetabular socket improves human locomotion?

<p>More inferior angling and reduced lateral spread (B)</p> Signup and view all the answers

What is the relationship between the length of lower limbs and trunk movement in bipedalism?

<p>Long lower limbs require a shorter, lighter trunk to minimize swaying (A)</p> Signup and view all the answers

What structures pass through the greater sciatic foramen?

<p>The sciatic nerve, gluteal nerves and vessels, and the pudendal nerve and vessels pass through the greater sciatic foramen.</p> Signup and view all the answers

What is the role of the sacrospinous and sacrotuberous ligaments in the pelvic diaphragm?

<p>They help create the greater and lesser sciatic foramina and provide support for the pelvic structures.</p> Signup and view all the answers

Which muscles are involved with the obturator fascia, and where do they extend?

<p>The obturator internus and externus muscles are associated with the obturator fascia, extending from the obturator membrane to their respective tendons.</p> Signup and view all the answers

How does the internal pudendal artery relate to the structures it supplies?

<p>The internal pudendal artery follows the pudendal nerve and supplies blood to the perineal region and external genitalia.</p> Signup and view all the answers

What passes through the lesser sciatic foramen?

<p>The tendon of the obturator internus muscle passes through the lesser sciatic foramen.</p> Signup and view all the answers

What is the function of the lesser sciatic foramen in pelvic anatomy?

<p>It allows the passage of the obturator internus tendon out and the pudendal nerve and vessels in.</p> Signup and view all the answers

How do superior and inferior pubic ligaments contribute to pelvic stability?

<p>They reinforce the pubic symphysis, enhancing the mechanical link between the limbs.</p> Signup and view all the answers

What role does the pelvic structure play in supporting bipedalism?

<p>The pelvic structure provides stability and balance for upright walking by forming a basin that supports the body's weight.</p> Signup and view all the answers

Describe the composition of the joint structure between the pubic bones.

<p>It consists of bone, hyaline cartilage, fibrocartilage, and is connected by fibers.</p> Signup and view all the answers

What role do the pelvic diaphragm muscles play in the pelvic cavity?

<p>They close off the pelvic cavity and support the pelvic organs.</p> Signup and view all the answers

How does pelvic sexual dimorphism relate to parturition?

<p>Pelvic sexual dimorphism enables females to have a wider pelvic inlet and outlet, facilitating easier childbirth.</p> Signup and view all the answers

Which bones contribute to the formation of the pelvic girdle?

<p>The pelvic girdle is formed by the sacrum and two os coxa, which include the ilium, pubis, and ischium.</p> Signup and view all the answers

Why is the ground reaction force significant in relation to the pubic symphysis?

<p>The orientation of the pubic symphysis allows better transmission of ground reaction forces through the posterior link.</p> Signup and view all the answers

What evolutionary pressures shaped the human pelvis's function?

<p>Evolutionary pressures included the need for efficient locomotion and the ability to give birth to larger-brained offspring.</p> Signup and view all the answers

How are the pelvic walls important in maintaining pelvic organ stability?

<p>The pelvic walls provide support and protect the pelvic viscera by maintaining a stable, closed cavity.</p> Signup and view all the answers

What biomechanical challenges does the female pelvis face during parturition?

<p>The female pelvis must adapt to the pressures of fetal descent while maintaining stability to prevent injury during childbirth.</p> Signup and view all the answers

How does the acetabulum relate to the pelvic bones?

<p>The acetabulum is the socket formed by the fusion of the ilium, pubis, and ischium, where the femur articulates.</p> Signup and view all the answers

What is the significance of the pelvic viscera being held in a 'bowl' shape?

<p>The 'bowl' shape of the pelvis effectively supports and protects the pelvic viscera while allowing for bodily movements.</p> Signup and view all the answers

What role does the pelvis play in the transfer of ground reaction forces?

<p>The pelvis efficiently transmits ground reaction forces between the vertebrae and limbs, allowing for effective weight distribution.</p> Signup and view all the answers

Describe the distinguishing features of the true pelvis compared to the false pelvis.

<p>The true pelvis is located below the pelvic brim and forms the bony walls of the pelvic cavity, whereas the false pelvis is above the pelvic brim, mainly composed of the ilium.</p> Signup and view all the answers

What structures are associated with the pelvic outlet?

<p>The pelvic outlet includes the ischial tuberosities, ischiopubic rami, sacrotuberous ligaments, and it is sealed by muscles and fascia.</p> Signup and view all the answers

What anatomical features make up the pelvic brim?

<p>The pelvic brim consists of the sacral promontory, sacral alae, iliopectineal line, and the symphysis pubis.</p> Signup and view all the answers

How does the obturator fascia relate to the obturator internus muscle?

<p>The obturator fascia covers the obturator internus muscle and plays a role in structural support and compartmentalization within the pelvis.</p> Signup and view all the answers

Explain the significance of the ground reaction force in pelvic mechanics.

<p>Ground reaction force is crucial for maintaining balance and stability, influencing how forces are transmitted through the pelvic girdle.</p> Signup and view all the answers

What are ischial tuberosities and their significance in the context of the pelvic outlet?

<p>Ischial tuberosities are bony prominences that form part of the pelvic outlet and serve as attachment points for ligaments and muscles.</p> Signup and view all the answers

Define the terms 'true pelvis' and 'false pelvis' in relation to pelvic anatomy.

<p>The true pelvis refers to the part of the pelvis below the pelvic brim involved in containing pelvic organs, while the false pelvis is above it and primarily houses the abdominal organs.</p> Signup and view all the answers

What is the primary stabilizing factor for the sacroiliac joint in the frontal plane?

<p>The dorsal ligaments, including the iliolumbar and dorsal interosseous sacroiliac ligaments, provide primary stabilization.</p> Signup and view all the answers

Why is the sacroiliac joint referred to as a ‘keystone’ joint?

<p>It is called a ‘keystone’ joint because it plays a crucial role in maintaining pelvic stability and distributing loads effectively.</p> Signup and view all the answers

How do micro tears in fibrocartilage affect the sacroiliac joint post-pregnancy?

<p>Micro tears can lead to the formation of a fluid-filled capsule, potentially resulting in joint instability or pain.</p> Signup and view all the answers

What role does the orientation of the sacroiliac joint play in its function?

<p>The wedged orientation with curved auricular surfaces facilitates weight transfer and limits excessive movement.</p> Signup and view all the answers

What happens to the tension on the dorsal ligaments during increased movement of the sacroiliac joint?

<p>Increased movement leads to greater tension on the dorsal ligaments, holding the ilium to the sacrum more securely.</p> Signup and view all the answers

What is the significance of ischial spines in bipedal efficiency during pregnancy?

<p>Ischial spines enhance bipedal efficiency and help reduce visceral prolapse in pregnant females.</p> Signup and view all the answers

How do pelvic adaptations influence trunk dynamics in bipedal locomotion?

<p>Pelvic adaptations, like a broader sacrum and wider acetabular space, stabilize the trunk's center of gravity for efficient movement.</p> Signup and view all the answers

Explain how pre-birth work capacity serves as a selection pressure in human pelvic evolution.

<p>Pre-birth work capacity influenced pelvic shape evolution more than birth itself, favoring traits that optimize movement efficiency.</p> Signup and view all the answers

Why is the angling of the acetabular socket important for human bipedalism?

<p>The acetabular socket's angle allows feet to fall within pelvic width, facilitating stable and efficient bipedal movement.</p> Signup and view all the answers

Discuss the role of trunk inertia in maintaining bipedal stability.

<p>Trunk inertia must match lower limb inertia to minimize swaying during locomotion, thus reducing energy expenditure.</p> Signup and view all the answers

What impact does body size have on bipedal efficiency according to the text?

<p>Larger body size is associated with improved bipedal efficiency, aiding in movement stability.</p> Signup and view all the answers

Describe the structural features of the human pelvis that enhance movement efficiency.

<p>Human pelvis features such as a flared ilia and deepened ilial neck enhance rotational and frontal movement efficiency.</p> Signup and view all the answers

How does the length and weight of lower limbs affect pelvis dynamics?

<p>Long and heavy lower limbs require a counterbalancing trunk to maintain stability during movement.</p> Signup and view all the answers

What is the primary hormone secreted by the zona glomerulosa and its main function?

<p>Aldosterone, which regulates sodium and water retention.</p> Signup and view all the answers

What condition can result from tumors or hyperplasia in the zona fasciculata?

<p>Cushing's disease.</p> Signup and view all the answers

What are the main hormones secreted by pancreatic islet cells and their corresponding cell types?

<p>Glucagon from alpha cells, insulin from beta cells, and somatostatin from delta cells.</p> Signup and view all the answers

At what age does the zona reticularis typically become fully developed?

<p>Around 3 years of age.</p> Signup and view all the answers

What hormone is predominantly secreted by pinealocytes?

<p>Melatonin</p> Signup and view all the answers

What is the role of somatostatin in the endocrine pancreas?

<p>It inhibits the secretion of glucagon and insulin.</p> Signup and view all the answers

What is the primary structural component of the pineal gland that gives it a 'stringy' appearance?

<p>Astrocytes</p> Signup and view all the answers

What are Herring bodies in the context of the posterior pituitary?

<p>They are storage sites for hormones.</p> Signup and view all the answers

Where is the pineal gland located within the brain?

<p>Posterior wall of the third ventricle</p> Signup and view all the answers

What is the composition of brain sand found in the pineal gland?

<p>Calcium and magnesium salts</p> Signup and view all the answers

What cell type in the anterior pituitary is characterized by basophilic staining?

<p>Basophils</p> Signup and view all the answers

What cells surround and support pinealocytes in the pineal gland?

<p>Astrocytes</p> Signup and view all the answers

What is the main function of PP-cells in the pancreas?

<p>PP-cells primarily secrete pancreatic polypeptide, which upregulates gastric chief cells and inhibits bile and pancreatic enzyme secretion.</p> Signup and view all the answers

How does pregnancy affect pancreatic secretions?

<p>Pregnancy can alter pancreatic secretions, leading to changes in insulin production and regulation of glucose metabolism.</p> Signup and view all the answers

What distinguishes acidophils in the anterior pituitary?

<p>They stain with acid dyes and produce growth hormone.</p> Signup and view all the answers

What are the main blood supply sources for the thyroid gland?

<p>The thyroid gland receives blood from the superior thyroid arteries via the external carotid and the inferior thyroid arteries via the thyrocervical trunk.</p> Signup and view all the answers

What type of nerve fibers are associated with the posterior pituitary?

<p>Nerve fibers from the hypothalamus</p> Signup and view all the answers

Describe the anatomical location of the thyroid gland in relation to other structures.

<p>The thyroid gland is located deep to the cervical strap muscles and sits just inferior to the thyroid and cricoid cartilages.</p> Signup and view all the answers

Explain the relationship between hyperthyroidism and pancreatic function.

<p>Hyperthyroidism may lead to increased metabolic demands, potentially impacting insulin and glucagon secretion from the pancreas.</p> Signup and view all the answers

What is the function of the pyramidal lobe of the thyroid gland?

<p>The pyramidal lobe is a remnant of thyroid migration, usually pointed toward the midline superiorly.</p> Signup and view all the answers

What is the consequence of inhibiting pancreatic enzyme secretion?

<p>Inhibiting pancreatic enzyme secretion can lead to malabsorption and nutrient deficiencies due to insufficient digestion.</p> Signup and view all the answers

Outline the venous drainage of the thyroid gland.

<p>The superior and middle thyroid veins drain into the internal jugular vein, while the inferior thyroid veins can drain into the brachiocephalic vein, IJV, or SVC.</p> Signup and view all the answers

Identify the clinical relevance of Cushing’s Syndrome to the pancreas.

<p>Cushing’s Syndrome can result in increased insulin resistance and alterations in glucose metabolism due to excess cortisol.</p> Signup and view all the answers

Which nerves are primarily responsible for the sympathetic innervation of the thyroid gland?

<p>Sympathetic innervation to the thyroid gland comes from the cervical ganglia, specifically the superior, middle, and inferior cervical ganglia.</p> Signup and view all the answers

What type of cells in the adrenal medulla synthesize and secrete adrenaline and noradrenaline?

<p>Chromaffin cells</p> Signup and view all the answers

What anatomical structure connects the two lobes of the thyroid gland?

<p>The two lobes of the thyroid gland are connected by an isthmus.</p> Signup and view all the answers

Identify the arteries that arise from the external carotid and supply the superior portion of the thyroid gland.

<p>The external carotid artery gives rise to the superior thyroid arteries that supply the superior portion of the thyroid gland.</p> Signup and view all the answers

Which arteries primarily supply blood to the adrenal glands?

<p>Paired adrenal arteries from the abdominal aorta</p> Signup and view all the answers

What variations exist in the drainage pathway of the inferior thyroid veins?

<p>The inferior thyroid veins can drain into the brachiocephalic vein, internal jugular vein, or superior vena cava.</p> Signup and view all the answers

How does drainage occur in the adrenal glands?

<p>From the cortex to the medulla, leading to the central adrenomedullary vein and then to the renal veins.</p> Signup and view all the answers

What is the role of sympathetic innervation in the function of the adrenal medulla?

<p>It stimulates the release of catecholamines.</p> Signup and view all the answers

Identify the three zones of the adrenal cortex in order from superficial to deep.

<p>Zona Glomerulosa, Zona Fasciculata, Zona Reticularis</p> Signup and view all the answers

What is the histological appearance of the zona glomerulosa?

<p>Small curved cell columns with dark round nuclei.</p> Signup and view all the answers

How does the adrenal medulla's response to stress differ from that of normal sympathetic nerve activity?

<p>It has a longer-lasting and more systemic effect.</p> Signup and view all the answers

What effect do parasympathetic nerves have on blood vessels in the adrenal glands?

<p>They induce vasoconstriction to minimize the release of substances into the blood.</p> Signup and view all the answers

Where is the pituitary gland located within the skull?

<p>The pituitary gland is located in the sella turcica of the sphenoid bone.</p> Signup and view all the answers

What type of tissue primarily composes the anterior pituitary?

<p>The anterior pituitary is primarily composed of epithelial glandular tissue.</p> Signup and view all the answers

What hormones are secreted by acidophils in the anterior pituitary?

<p>Acidophils secrete Growth Hormone (GH) and Prolactin.</p> Signup and view all the answers

Which hormones does the posterior pituitary store?

<p>The posterior pituitary stores Anti-Diuretic Hormone (ADH) and Oxytocin.</p> Signup and view all the answers

What is the primary function of the hypophyseal portal system?

<p>The hypophyseal portal system connects hypothalamic hormones to the anterior pituitary.</p> Signup and view all the answers

What distinguishes the pars tuberalis from other regions of the pituitary gland?

<p>The pars tuberalis is wrapped around the infundibulum and has a rich vascular supply.</p> Signup and view all the answers

Which nuclei in the hypothalamus produce ADH?

<p>ADH is produced by the supraoptic nucleus of the hypothalamus.</p> Signup and view all the answers

What role do pituicytes play in the posterior pituitary?

<p>Pituicytes are specialized glial cells that regulate the release of hormone contents from Herring bodies.</p> Signup and view all the answers

What is the function of melanocyte-stimulating hormone (MSH) secreted by basophils?

<p>MSH primarily influences pigmentation in the skin.</p> Signup and view all the answers

What anatomical structure connects the posterior pituitary to the hypothalamus?

<p>The infundibulum connects the posterior pituitary to the hypothalamus.</p> Signup and view all the answers

How are Herring bodies characterized in the posterior pituitary?

<p>Herring bodies are swollen secretory terminals that store hormones.</p> Signup and view all the answers

What type of cells does the pars intermedia primarily consist of?

<p>The pars intermedia consists mostly of basophilic cells.</p> Signup and view all the answers

What is the primary role of the portal venous system related to the pituitary gland?

<p>It transports hormones from the hypothalamus to the anterior pituitary for regulation.</p> Signup and view all the answers

What is the significance of colloid cysts in the pars intermedia?

<p>Colloid cysts are remnants of Rathke's pouch found in the pars intermedia.</p> Signup and view all the answers

What hormone is primarily secreted by the zona glomerulosa of the adrenal cortex?

<p>Aldosterone (D)</p> Signup and view all the answers

Which type of cells in the pancreatic islets primarily secrete insulin?

<p>Beta cells (A)</p> Signup and view all the answers

Which adrenal cortex layer is characterized by having radially orientated fascicle-like tubes of cells?

<p>Zona Fasciculata (C)</p> Signup and view all the answers

Which hormone is secreted primarily by the zona reticularis?

<p>DHEA (A)</p> Signup and view all the answers

What is the primary function of somatostatin in the pancreatic islets?

<p>Inhibiting insulin and glucagon secretion (A)</p> Signup and view all the answers

What is the primary blood supply to the thyroid gland?

<p>Superior thyroid arteries from the external carotid (C)</p> Signup and view all the answers

Which anatomical structure is typically located deep to the cervical strap muscles?

<p>Thyroid gland (D)</p> Signup and view all the answers

The pyramidal lobe of the thyroid is a remnant of which developmental feature?

<p>Thyroid migration (C)</p> Signup and view all the answers

Which of the following veins drains directly into the Internal Jugular Vein?

<p>Middle thyroid vein (A), Superior thyroid vein (B)</p> Signup and view all the answers

Which system is responsible for the sympathetic innervation of the thyroid gland?

<p>Cervical ganglia (A)</p> Signup and view all the answers

The inferior thyroid arteries arise from which arterial trunk?

<p>Thyrocervical trunk (D)</p> Signup and view all the answers

Which type of vein can drain into various structures such as the brachiocephalic vein or the superior vena cava?

<p>Inferior thyroid vein (C)</p> Signup and view all the answers

What connects the two lobes of the thyroid gland?

<p>Thyroid isthmus (D)</p> Signup and view all the answers

What is the primary function of chromaffin cells in the adrenal medulla?

<p>To release catecholamines into the bloodstream (D)</p> Signup and view all the answers

Which structure primarily drains blood from the adrenal gland?

<p>Central adrenomedullary vein (B)</p> Signup and view all the answers

What type of nerve fibers are responsible for the sympathetic innervation of the adrenal gland?

<p>Lesser splanchnic nerve fibers from T10-11 (B)</p> Signup and view all the answers

Which of the following correctly describes the sequence of blood supply to the adrenal gland?

<p>Adrenal arteries - Cortex - Medulla (A)</p> Signup and view all the answers

What is the histological feature that distinguishes the adrenal cortex from the medulla?

<p>Acidophilic cytoplasm in cortical cells (D)</p> Signup and view all the answers

Which zone of the adrenal cortex contains small curved cell columns with a spongy appearance?

<p>Zona Glomerulosa (A)</p> Signup and view all the answers

Which characteristic of the adrenal medulla contributes to its systemic effects during stress responses?

<p>Release of catecholamines into the bloodstream (D)</p> Signup and view all the answers

What role do the paired adrenal arteries play in the blood supply to the adrenal glands?

<p>They deliver blood to the cortex first (B)</p> Signup and view all the answers

What is the main function of pinealocytes in the pineal gland?

<p>Regulate the sleep-wake cycle by secreting melatonin (C)</p> Signup and view all the answers

Which type of glial cells are characterized by a star-shaped appearance with dark nuclei?

<p>Astrocytes (D)</p> Signup and view all the answers

What is the composition of 'brain sand' found in the pineal gland?

<p>A combination of calcium and magnesium salts (C)</p> Signup and view all the answers

Which part of the pituitary gland is responsible for storing hormones in nerve endings?

<p>Posterior pituitary (D)</p> Signup and view all the answers

What is the primary role of acidophils found in the anterior pituitary?

<p>Producing growth hormones and prolactin (D)</p> Signup and view all the answers

Which structure is associated with the maintenance of the blood-brain barrier?

<p>Astrocytes (B)</p> Signup and view all the answers

What type of cells make up the primary secretory component of the pineal gland?

<p>Pinealocytes (B)</p> Signup and view all the answers

Where is the pineal gland located within the brain?

<p>Posterior wall of the third ventricle (D)</p> Signup and view all the answers

Which cell types are primarily found within the anterior pituitary?

<p>Basophils and acidophils (A)</p> Signup and view all the answers

What is the significance of Herring bodies in the posterior pituitary?

<p>They store hormones for release into circulation (D)</p> Signup and view all the answers

What is the primary function of thyroglobulin in the thyroid gland?

<p>It binds to thyroid hormones for storage. (A)</p> Signup and view all the answers

Which type of cells in the thyroid gland are responsible for secreting calcitonin?

<p>Parafollicular cells (C)</p> Signup and view all the answers

Which thyroid hormone is considered to be more potent?

<p>Triiodothyronine (T3) (B)</p> Signup and view all the answers

What is the primary function of the Chief cells in the parathyroid gland?

<p>Secretion of parathyroid hormone when calcium levels are low. (B)</p> Signup and view all the answers

Which of the following accurately describes T3's and T4's action in the body?

<p>They are cleaved from thyroglobulin and released into the bloodstream. (D)</p> Signup and view all the answers

Which of the following is true about the Oxyphilic cells in the parathyroid gland?

<p>They often cluster and are identifiable by their acidophilic cytoplasm. (B)</p> Signup and view all the answers

What is the effect of parathyroid hormone (PTH) on the gastrointestinal tract?

<p>It increases calcium absorption. (C)</p> Signup and view all the answers

What does the absence of parasympathetic innervation in the vagus nerve indicate about its role?

<p>It primarily modulates sympathetic tone. (C)</p> Signup and view all the answers

What major role does calcitonin play in calcium homeostasis?

<p>It inhibits osteoclast activity. (A)</p> Signup and view all the answers

Which characteristic of the thyroid follicles aids in the storage of thyroid hormones?

<p>Large extracellular colloid lakes. (A)</p> Signup and view all the answers

What is the primary role of the infundibulum in the posterior pituitary gland?

<p>Facilitates the transport of hormones from the hypothalamus to the posterior pituitary. (C)</p> Signup and view all the answers

Which cell type in the anterior pituitary gland is responsible for secreting Growth Hormone?

<p>Acidophils (B)</p> Signup and view all the answers

What anatomical feature is the pituitary gland located within?

<p>Sella turcica (B)</p> Signup and view all the answers

Which hormone is secreted by the pars intermedia of the pituitary gland?

<p>Melanocyte Stimulating Hormone (MSH) (C)</p> Signup and view all the answers

What is the primary component of the posterior pituitary gland?

<p>Neurohypophysis (C)</p> Signup and view all the answers

Which type of cells are found predominantly in the pars tuberalis of the pituitary gland?

<p>Basophilic cells (B)</p> Signup and view all the answers

How do hormones from the hypothalamus reach the anterior pituitary?

<p>Through a portal venous system. (C)</p> Signup and view all the answers

Which of the following structures aids in the storage of Antidiuretic Hormone (ADH) in the posterior pituitary?

<p>Herring bodies (B)</p> Signup and view all the answers

What type of cytoplasm is characteristic of basophils in the anterior pituitary gland?

<p>Basic (B)</p> Signup and view all the answers

Where is the primary source of Oxytocin found?

<p>Hypothalamic nuclei (A)</p> Signup and view all the answers

Which gland is described as being wrapped around the infundibulum?

<p>Pars tuberalis of the pituitary gland (D)</p> Signup and view all the answers

What structure connects the neurons of the hypothalamic nuclei to the posterior pituitary gland?

<p>Infundibulum (C)</p> Signup and view all the answers

What do chromophobe cells in the pituitary gland primarily lack?

<p>Cytoplasmic granules (D)</p> Signup and view all the answers

Which of the following hormones is secreted by the anterior pituitary gland in response to stress?

<p>AdrenoCorticoTrophic Hormone (ACTH) (D)</p> Signup and view all the answers

Which anatomical landmark is generally aligned with the tip of the coccyx in the male pelvis?

<p>Pubic symphysis (A)</p> Signup and view all the answers

What is the most notable structure that derives from the first pharyngeal cleft?

<p>External ear (D)</p> Signup and view all the answers

What is the significant relationship of the broad ligament concerning the uterus and uterine tubes?

<p>It provides support to the vascular and nervous structures (B)</p> Signup and view all the answers

Which description most accurately characterizes the curvature of the rectum in relation to the sacrum?

<p>It exhibits a sigmoid pattern following the sacrum's contour (B)</p> Signup and view all the answers

At what location does the thyroid primarily begin its migration during development?

<p>Foramen caecum of the tongue (A)</p> Signup and view all the answers

What is the primary vascular supply to the pelvic organs originating from the internal iliac artery?

<p>Inferior vesicular artery (D)</p> Signup and view all the answers

Calcification in the pineal gland is most commonly associated with which demographic factor?

<p>Age and female prevalence (B)</p> Signup and view all the answers

Which of the following glands does NOT derive from the pouches formed during the fusion of gills?

<p>Thyroid gland (C)</p> Signup and view all the answers

How does the position of the pelvic inlet relate to the horizontal plane?

<p>It is roughly parallel to the horizontal plane (A)</p> Signup and view all the answers

What is the significance of the pyramidal lobe in relation to thyroid development?

<p>It serves as a remnant of the thyroglossal duct. (B)</p> Signup and view all the answers

What role does thyroid hormone play during fetal development?

<p>It accelerates alveolar septation and increases lung compliance. (A)</p> Signup and view all the answers

What effect does low maternal iodine have on the fetus?

<p>It leads to abnormal neural hormone development. (A)</p> Signup and view all the answers

What unique adaptation do axolotls have regarding respiration?

<p>They can absorb oxygen through their gills and skin. (D)</p> Signup and view all the answers

How does thyroid hormone influence brown fat development?

<p>It promotes development through non-shivering thermogenesis. (D)</p> Signup and view all the answers

At what gestational age do thyroid follicles become functional?

<p>At 10-11 weeks GA. (A)</p> Signup and view all the answers

What is a potential consequence of the thyroid gland duct failing to close completely?

<p>Development of thyroid cancer. (B)</p> Signup and view all the answers

What condition is associated with higher levels of thyroid hormone late in fetal development?

<p>Development of brown fat for thermogenesis. (B)</p> Signup and view all the answers

What substance do axolotls primarily consume that is low in iodine?

<p>Worms, insects, and small fish. (C)</p> Signup and view all the answers

What role does the rectovesical pouch play in male anatomy?

<p>It separates the bladder and rectum. (B)</p> Signup and view all the answers

Which anatomical structure's relationship with the pelvic inlet is essential for understanding pelvic organ positioning?

<p>Pubic symphysis (C)</p> Signup and view all the answers

In the context of pregnancy, which structure's function is critical for maintaining an upright posture?

<p>Round ligament (B)</p> Signup and view all the answers

How does the inferior rectal artery relate to the internal pudendal artery?

<p>It branches directly from the internal pudendal artery. (C)</p> Signup and view all the answers

Which vessel is primarily responsible for the blood supply to the uterus?

<p>Uterine artery (C)</p> Signup and view all the answers

What is synthesized and secreted by chromaffin cells?

<p>Adrenaline and noradrenaline (A)</p> Signup and view all the answers

What typically occurs to the fetal cortex a couple of months after birth?

<p>It disappears. (A)</p> Signup and view all the answers

Which of the following statements accurately differentiates the fetal cortex from the adult cortex?

<p>The fetal cortex forms through two distinct waves of mesothelial cells. (D)</p> Signup and view all the answers

What is the purpose of the pre-synaptic sympathetic nerve in relation to chromaffin cells?

<p>To stimulate release of acetylcholine directly onto chromaffin cells. (B)</p> Signup and view all the answers

During development, how do mesothelial cells contribute to the formation of the fetal cortex?

<p>They migrate in two waves, influencing both fetal and adult cortex structures. (C)</p> Signup and view all the answers

What time frame marks the transition from the fetal cortex to the adult cortex formation?

<p>6-7 weeks in utero (B)</p> Signup and view all the answers

Which characteristic distinguishes chromaffin cells from other autonomic nerve cells?

<p>They are specialized post-synaptic autonomic nerve cells. (D)</p> Signup and view all the answers

What is a significant distinction regarding the tissue formation between fetal cortex and definitive adult cortex?

<p>The adult cortex results from two waves of mesothelial cell activity. (B)</p> Signup and view all the answers

What embryonic layer is primarily responsible for contributing to the development of structures such as the nervous system and skin?

<p>Ectoderm (D)</p> Signup and view all the answers

Which of the following structures is derived from the endoderm layer during embryonic development?

<p>Lining of the gastrointestinal tract (B)</p> Signup and view all the answers

Which cranial nerve is associated with structures that develop from the second pharyngeal arch?

<p>CN VII (Facial nerve) (C)</p> Signup and view all the answers

Which layer contributes to the formation of internal organs and the gastrointestinal tract?

<p>Endoderm (B)</p> Signup and view all the answers

Which embryonic layer is primarily involved in the formation of the musculoskeletal system and circulatory system?

<p>Mesoderm (D)</p> Signup and view all the answers

How does calcification of the pineal gland correlate with age and gender in South America?

<p>Calcification is observed in approximately 65% of individuals aged 2-87 and is more common in females as age increases.</p> Signup and view all the answers

What are the notable structures derived from the clefts and pouches of the pharyngeal arches?

<p>Clefts primarily form the external ear, while pouches give rise to structures such as the palatine tonsils, parathyroid glands, and thymus.</p> Signup and view all the answers

Explain the significance of the thyroid diverticulum in the development of the thyroid gland.

<p>The thyroid diverticulum is crucial as it forms the thyroglossal duct, which guides the thyroid gland's migration into the neck.</p> Signup and view all the answers

What is the consequence of failure in the closure of the thyroglossal duct during thyroid development?

<p>Failure to close can result in the formation of a thyroglossal duct cyst or an extra pyramidal lobe of the thyroid.</p> Signup and view all the answers

During thyroid development, from where does the thyroid gland originate?

<p>The thyroid gland originates from the foramen caecum of the tongue.</p> Signup and view all the answers

What are the two germ layers that give rise to the embryonic tissues?

<p>Surface ectoderm and endoderm.</p> Signup and view all the answers

Identify the cranial nerve associated with the second branchial arch.

<p>CNVII (Facial nerve).</p> Signup and view all the answers

What is a common pathological concern associated with the second pharyngeal arch?

<p>Anatomical anomalies or syndromes such as DiGeorge syndrome.</p> Signup and view all the answers

Explain the role of the palatine structure in embryonic development.

<p>The palatine serves as a key element in forming the palate and associated structures.</p> Signup and view all the answers

How do embryonic layers contribute to organ differentiation?

<p>Layers such as ectoderm, mesoderm, and endoderm differentiate into specific organs.</p> Signup and view all the answers

How does maternal iodine deficiency affect fetal neural development?

<p>It results in abnormal neural hormone development due to impaired fetal thyroid function.</p> Signup and view all the answers

What role does thyroid hormone play in lung development during fetal maturation?

<p>Thyroid hormone accelerates alveolar septation and increases lung compliance.</p> Signup and view all the answers

Describe the significance of brown fat development influenced by thyroid hormone during the late fetal period.

<p>Thyroid hormone stimulates the development of brown fat, which is important for non-shivering thermogenesis.</p> Signup and view all the answers

What physiological feature of the axolotls aids in their adaptation to their environment?

<p>Axolotls possess external gills and can breathe through their skin, enhancing respiratory efficiency in fluctuating water conditions.</p> Signup and view all the answers

Explain the impact of thyroid follicles being functional at 10-11 weeks gestational age.

<p>They begin producing thyroid hormones that are essential for fetal growth and development.</p> Signup and view all the answers

What mechanism does thyroid hormone utilize for effective lung maturation?

<p>TH promotes alveolar septation and enhances the compliance of the lung tissue.</p> Signup and view all the answers

How does thyroid hormone assist infants who are born prematurely?

<p>It supports lung development, allowing for improved respiratory function.</p> Signup and view all the answers

What is a consequence of the thyroid duct failing to close completely during development?

<p>It can lead to structural abnormalities or dysfunctions in thyroid hormone production.</p> Signup and view all the answers

Which hormone is released by the thyroid gland, and what is its effect on calcium levels?

<p>Calcitonin is released, and it decreases calcium levels.</p> Signup and view all the answers

From which pharyngeal pouch do the inferior parathyroid glands develop?

<p>They develop from the 3rd pharyngeal pouch.</p> Signup and view all the answers

What structures contribute to the development of the adrenal glands?

<p>Adrenal glands develop from neural crest cells and lateral plate mesoderm.</p> Signup and view all the answers

What cells in the adrenal gland are derived from neural crest cells?

<p>Medullary cells, also known as chromaffin cells.</p> Signup and view all the answers

Which embryological structure gives rise to the thymus?

<p>The thymus develops from the 3rd pharyngeal pouch.</p> Signup and view all the answers

What are the C-cells of the thyroid, and where do they originate from?

<p>C-cells release calcitonin and originate from the 4th pharyngeal pouch.</p> Signup and view all the answers

How many superior parathyroid glands are formed, and when do they develop?

<p>Two superior parathyroid glands are formed from the 4th pouch.</p> Signup and view all the answers

What effect do neural crest cells have during the development of adrenal glands?

<p>Neural crest cells form the adrenal medulla, which produces hormones like epinephrine.</p> Signup and view all the answers

What is the developmental origin of the anterior pituitary gland?

<p>It originates from the surface ectoderm of Rathke's pouch.</p> Signup and view all the answers

Which embryonic structure is responsible for the formation of the posterior pituitary?

<p>The posterior pituitary is derived from the neural tube ectoderm.</p> Signup and view all the answers

What physiological role does the hypothalamus play in relation to the pituitary gland?

<p>The hypothalamus controls the pituitary gland's hormone release through neurohormonal signals.</p> Signup and view all the answers

How does the development of the adrenal gland differ from that of other endocrine glands?

<p>The adrenal gland develops from both mesodermal and ectodermal origins.</p> Signup and view all the answers

What key role does the Pineal gland play in the endocrine system?

<p>The Pineal gland regulates circadian rhythms through the secretion of melatonin.</p> Signup and view all the answers

What is the significance of Rathke’s pouch in pituitary gland development?

<p>Rathke’s pouch serves as the precursor structure for the anterior pituitary.</p> Signup and view all the answers

What factors can affect the functional capacity of endocrine organs as they develop?

<p>Genetic signals and environmental influences during embryonic development can affect their function.</p> Signup and view all the answers

Which embryonic layer contributes to the formation of the thyroid gland?

<p>The thyroid gland originates from the endoderm layer.</p> Signup and view all the answers

How does the invagination of the stomodeum relate to endocrine gland development?

<p>The invagination of the stomodeum contributes to the formation of structures such as the pituitary gland.</p> Signup and view all the answers

Why is the location of the pituitary gland considered clinically significant?

<p>It is situated at the base of the brain, directly influencing numerous hormonal pathways.</p> Signup and view all the answers

Describe the relationship between the development of the endocrine pancreas and its function.

<p>The pancreas develops from both endoderm and mesoderm, affecting its dual role in hormone production and digestion.</p> Signup and view all the answers

What impact can embryonic developmental abnormalities have on endocrine organs?

<p>Abnormalities can lead to dysgenesis, resulting in hormonal imbalances or organ dysfunction.</p> Signup and view all the answers

In what way does the differentiation of Rathke's pouch aid in the structure of the adult pituitary?

<p>The differentiation establishes the adenohypophysis, which assumes a glandular appearance.</p> Signup and view all the answers

What is the embryological significance of the forebrain concerning the posterior pituitary?

<p>The forebrain's development influences the posterior pituitary's structural and functional integration with the hypothalamus.</p> Signup and view all the answers

How does embryonic connective tissue contribute to the development of endocrine organs?

<p>Connective tissue provides support and directs the growth of cells forming the glands.</p> Signup and view all the answers

What is the role of DHEA secreted by the fetal adrenal cortex?

<p>DHEA regulates the maturation of the lungs, gastrointestinal tract, and parturition.</p> Signup and view all the answers

Which zone of the fetal adrenal cortex is responsible for producing aldosterone and when is it critical?

<p>The Zona Glomerulosa produces aldosterone, which is critical during the 3rd trimester for postnatal salt preservation.</p> Signup and view all the answers

At what gestational week does the fetal pancreas begin to function in maintaining glucose homeostasis?

<p>The fetal pancreas begins to function at week 10.</p> Signup and view all the answers

How do islet cells in the pancreas develop and what are their types?

<p>Islet cells develop from delaminating endocrine cells and include Alpha, Beta, Delta, and PP-cells.</p> Signup and view all the answers

What impacts the development of islet cells during fetal development?

<p>Factors such as poor placental vasculature, maternal diabetes, and fetal malnutrition impact islet cell development.</p> Signup and view all the answers

Which fetal adrenal cortex layer appears first and what does it secrete?

<p>The Zona Fasciculata appears in the 2nd trimester and primarily secretes cortisol.</p> Signup and view all the answers

What happens to the fetal adrenal cortex after birth?

<p>The fetal cortex regresses in the first 2 months of life while the adult cortex continues to grow.</p> Signup and view all the answers

What signifies the most critical interaction between the placenta and the fetal adrenal glands?

<p>The placenta and fetal adrenal glands interact through the secretion of hormones like progesterone and estrogen.</p> Signup and view all the answers

What are the main roles of Bowman’s capsule in the urinary system?

<p>Bowman's capsule filters blood to form urine and collects the filtrate from the glomerulus.</p> Signup and view all the answers

How does the structure of the glomerulus contribute to its function in filtration?

<p>The glomerulus consists of coiled fenestrated capillaries, allowing selective filtration of blood based on size and charge.</p> Signup and view all the answers

Explain the significance of the Juxtaglomerular cells in the kidney.

<p>Juxtaglomerular cells regulate blood pressure by releasing renin in response to changes in blood flow and sodium concentration.</p> Signup and view all the answers

What is the primary function of the Loop of Henle in urine concentration?

<p>The Loop of Henle creates a concentration gradient by reabsorbing water and salts, which is essential for urine concentration.</p> Signup and view all the answers

Describe the mechanisms involved in the process of selective reabsorption in the nephron.

<p>Selective reabsorption occurs primarily in the proximal convoluted tubule, where water, glucose, and salts are reabsorbed into the blood.</p> Signup and view all the answers

What is the role of the aorta in renal blood flow regulation?

<p>The aorta directs blood flow to the kidneys and can constrict to redirect blood to more active tissues.</p> Signup and view all the answers

How do pre-synaptic and post-synaptic neurons interact in the renal system?

<p>Pre-synaptic neurons release neurotransmitters that bind to receptors on post-synaptic neurons, facilitating renal regulation.</p> Signup and view all the answers

Explain how the body redirects cardiac output to active tissues during renal constriction.

<p>During renal artery constriction, the body prioritizes blood flow to tissues with higher metabolic demands, ensuring efficient oxygen delivery.</p> Signup and view all the answers

What implications does the redirection of blood flow have on renal function?

<p>Redirection can reduce renal perfusion pressure, potentially affecting urine formation and electrolyte balance.</p> Signup and view all the answers

Describe the relationship between renal blood supply and overall cardiac output.

<p>Renal blood supply is a component of cardiac output, which is distributed based on the metabolic activity of various tissues.</p> Signup and view all the answers

What is the role of the vasa recta in maintaining the medullary concentration gradient?

<p>The vasa recta helps recycle urea and maintain the osmotic gradient by allowing countercurrent exchange in the renal medulla.</p> Signup and view all the answers

Describe how countercurrent multiplication contributes to urine concentration within the nephron.

<p>Countercurrent multiplication uses selective ion channels in the ascending and descending limbs to create a concentration gradient, enhancing water reabsorption.</p> Signup and view all the answers

Explain the significance of recycling urea in the interstitial fluid and ductules.

<p>Recycling urea reinforces the osmotic gradient, thereby facilitating further water reabsorption in the nephron.</p> Signup and view all the answers

What anatomical structure plays a key role in establishing a scaled medullary concentration gradient?

<p>The loop of Henle is crucial for establishing and maintaining the medullary concentration gradient.</p> Signup and view all the answers

How does the arrangement of the efferent arteriole and vasa recta facilitate renal function?

<p>The efferent arteriole leads to the vasa recta, enabling the supply of oxygenated blood while allowing efficient reabsorption and secretion processes in the nephron.</p> Signup and view all the answers

What two main components make up a renal lobe?

<p>Cortex and medullary pyramid.</p> Signup and view all the answers

Identify the key structures found in the renal cortex.

<p>Glomeruli, convoluted tubules, and medullary rays.</p> Signup and view all the answers

What is the pathway for waste collection in the kidney from minor calyces to the ureter?

<p>Minor calyces → Major calyces → Renal pelvis → Ureter.</p> Signup and view all the answers

Name the primary structures contained within the medullary pyramid.

<p>Loop of Henle, collecting ducts, and papilla.</p> Signup and view all the answers

How do minor calyces function in the renal system?

<p>Minor calyces cup the papilla to collect urine from the medullary pyramids.</p> Signup and view all the answers

What is the relationship between nephron count and kidney function?

<p>Each kidney contains about 1 million nephrons that are vital for filtration.</p> Signup and view all the answers

Describe the functional significance of the renal columns.

<p>Renal columns extend into the medulla and support the renal lobes.</p> Signup and view all the answers

What is located at the urinary pole of the nephron?

<p>The point where the renal tubule exits from the Bowman’s capsule.</p> Signup and view all the answers

Explain the importance of the collecting ducts in renal physiology.

<p>Collecting ducts concentrate urine and regulate water balance.</p> Signup and view all the answers

What connects the structures of the renal cortex to the minor calyces?

<p>Medullary rays connect convoluted tubules and collecting ducts to minor calyces.</p> Signup and view all the answers

What structural adaptation do densa cells have that enhances their efficiency?

<p>Densa cells have a unique structure that increases surface area for better transport efficiency.</p> Signup and view all the answers

How do peritubular capillaries differ from the vasa recta in terms of their anatomical position?

<p>Peritubular capillaries are located around the nephron tubules, while the vasa recta are found parallel to the loops of Henle in the medulla.</p> Signup and view all the answers

Why do medullary rays increase in size toward the medulla?

<p>Medullary rays increase in size as they aggregate from a greater number of nephrons closer to the medulla.</p> Signup and view all the answers

What role do juxtaglomerular nephrons play in renal function?

<p>Juxtaglomerular nephrons are crucial for concentrating urine and regulating blood pressure.</p> Signup and view all the answers

How does the structure of cortical tubules aid in their function?

<p>Cortical tubules consist of both proximal and distal sections which facilitate efficient reabsorption and secretion processes.</p> Signup and view all the answers

What distinguishes proximal convoluted tubules from distal ones in terms of morphology?

<p>Proximal convoluted tubules have bushy, 'fluffy' microvilli that enhance absorptive surface area.</p> Signup and view all the answers

In what way does the gradient of cortical nephrons affect their drainage into medullary rays?

<p>The gradient allows for efficient collection of filtrate, leading to optimal drainage into the medullary rays.</p> Signup and view all the answers

What is the significance of cut transversal sections of collecting ducts in histological studies?

<p>They provide insights into the structure-function relationship of collecting ducts in fluid regulation.</p> Signup and view all the answers

What is the physiological importance of the directional formation of glomeruli?

<p>The directional formation enhances filtration efficiency and blood flow dynamics through the nephron.</p> Signup and view all the answers

How does the increase in size of medullary rays relate to nephron function?

<p>An increase in size of medullary rays indicates aggregation from more nephrons, enhancing filtration efficiency.</p> Signup and view all the answers

What are the implications of nephron structure for fluid transport across membranes?

<p>Nephron structure, characterized by various tubule types, allows for targeted reabsorption and secretion, enhancing fluid transport.</p> Signup and view all the answers

Why is it essential for nephrons to have efficient transport mechanisms?

<p>Efficient transport mechanisms in nephrons are essential for regulating electrolyte balance and fluid homeostasis in the body.</p> Signup and view all the answers

What is the role of collecting ducts within the medullary rays?

<p>Collecting ducts within the medullary rays are responsible for the final concentration of urine before it reaches the renal pelvis.</p> Signup and view all the answers

How does the structural configuration of the proximal convoluted tubule support its function?

<p>The proximal convoluted tubule's structure, with its extensive microvilli, maximizes absorption of water and nutrients.</p> Signup and view all the answers

What impact does the arrangement of blood vessels around nephrons have on renal physiology?

<p>The arrangement of peritubular capillaries and vasa recta allows for efficient exchange of substances and optimal nephrons function.</p> Signup and view all the answers

What structural adaptations enable the proximal convoluted tubule (PCT) to engage in active transport?

<p>The PCT has a high amount of microvilli for increased surface area and numerous mitochondria for energy.</p> Signup and view all the answers

How do the epithelial cells of the distal convoluted tubule (DCT) differ from those in the proximal convoluted tubule (PCT)?

<p>DCT cells are generally more cuboidal with fewer microvilli and less machinery for active transport compared to PCT cells.</p> Signup and view all the answers

What is the primary function of the Loop of Henle in the nephron?

<p>The Loop of Henle creates a concentration gradient in the medulla, crucial for water reabsorption.</p> Signup and view all the answers

Describe the histological adaptations of collecting ducts and their significance.

<p>Collecting ducts have cuboidal epithelium and increased nuclei, allowing for hormonal sensitivity and regulation of water permeability.</p> Signup and view all the answers

What is the role of transitional epithelium in the ureter?

<p>Transitional epithelium protects against stretch as it accommodates varying volumes of urine.</p> Signup and view all the answers

Explain how urine is moved from the ureters to the bladder.

<p>Urine is moved by peristalsis in the ureters, assisted by bladder pressure during filling.</p> Signup and view all the answers

What is the anatomical relationship of the ureter to the gonadal vessels?

<p>The ureter passes behind the gonadal vessels as it travels retroperitoneally.</p> Signup and view all the answers

What differentiates the muscular layers of the bladder compared to the ureter?

<p>The bladder has a thick detrusor muscle, while the ureter has a simpler muscularis coat adapted for peristalsis.</p> Signup and view all the answers

Identify the significance of the micturition reflex and the nerves involved.

<p>The micturition reflex triggers detrusor contraction and is linked to stretch-sensitive afferent fibers.</p> Signup and view all the answers

How do the upper and lower ureters differ in terms of blood supply?

<p>The upper ureter is supplied by renal arteries, while the lower ureter receives blood from vesicular arteries.</p> Signup and view all the answers

What structural features characterize the bladder's trigone area?

<p>The trigone is marked by its smooth surface and is bordered by the ureteral openings and the urethral exit.</p> Signup and view all the answers

What key role does the peritoneal covering play in the expansion of the bladder?

<p>The peritoneal covering allows safer expansion of the bladder, preventing surrounding structures from wrapping around it.</p> Signup and view all the answers

How does the structure of the detrusor muscle contribute to bladder function?

<p>The detrusor muscle, which is thickened in the bladder wall, facilitates contraction to expel urine efficiently.</p> Signup and view all the answers

Explain the relationship between the ureters and surrounding vasculature.

<p>Ureters run closely alongside small capillary components that supply them, allowing for efficient blood circulation.</p> Signup and view all the answers

What anatomical structures contribute to the kidney's highly efficient filtration process?

<p>The glomerulus and its surrounding Bowman’s capsule facilitate efficient filtration due to their complex architecture and unique cellular characteristics.</p> Signup and view all the answers

How is the structure of the nephron tubules related to their specific functions?

<p>Each segment of the nephron has specialized epithelial cells that adapt to their functional tasks, such as reabsorption or secretion, enabling efficient urine formation.</p> Signup and view all the answers

What role does the kidney's blood supply play in renal function?

<p>The renal artery provides a rich blood supply, which is crucial for filtering waste and regulating electrolytes, while the renal vein removes filtered blood.</p> Signup and view all the answers

What processes are involved in the storage and evacuation of urine in the bladder?

<p>Urine is stored in the bladder through relaxation of the detrusor muscle and evacuated via micturition, which involves coordinated contractions of the bladder and relaxation of the sphincters.</p> Signup and view all the answers

Why is the complex cellular anatomy of the glomerulus significant?

<p>The glomerulus' structure allows for selective filtration of blood, removing waste while retaining essential elements such as proteins and cells.</p> Signup and view all the answers

What role does the vasa recta play in the context of the efferent arteriole?

<p>The vasa recta recycles urea between ductules and interstitial fluid, contributing to the medullary concentration gradient.</p> Signup and view all the answers

How does countercurrent multiplication function within the nephron?

<p>Countercurrent multiplication utilizes selective ion channels in the ascending and descending limbs to create concentration gradients.</p> Signup and view all the answers

What is the primary function of the aorta in relation to blood flow?

<p>The aorta's primary function is to distribute oxygenated blood from the heart to the rest of the body.</p> Signup and view all the answers

What is the significance of the scaled medullary concentration gradient created in the nephron?

<p>The scaled medullary concentration gradient allows for efficient reabsorption of water and solutes, crucial for urine concentration.</p> Signup and view all the answers

How do renal blood flow patterns adjust during times of cardiac output changes?

<p>Renal blood flow can constrict to redirect blood to more active tissues during periods of increased cardiac output.</p> Signup and view all the answers

In what way does urea recycling contribute to renal function?

<p>Urea recycling aids in establishing and maintaining osmotic gradients in the medulla, which is essential for water reabsorption.</p> Signup and view all the answers

What role do synapses in the renal system play in regulating kidney function?

<p>Synapses between pre- and post-synaptic neurons in the kidneys are essential for transmitting signals that regulate kidney function.</p> Signup and view all the answers

What structures are involved in the formation of the medullary concentration gradient?

<p>The concentration gradient is formed by the interactions of the loop of Henle, vasa recta, and surrounding interstitial fluid.</p> Signup and view all the answers

What is the significance of redirecting blood flow from the kidneys during physical activity?

<p>Redirecting blood flow from the kidneys during physical activity allows for increased blood supply to muscles and vital organs that require more oxygen.</p> Signup and view all the answers

What effects do sympathetic neural signals have on renal blood flow?

<p>Sympathetic neural signals typically decrease renal blood flow by causing vasoconstriction of renal arteries.</p> Signup and view all the answers

What role do macula densa cells play in the homeostasis of sodium and chloride levels?

<p>Macula densa cells detect low sodium and chloride concentrations, signaling juxtaglomerular cells to release renin, which increases GFR.</p> Signup and view all the answers

Describe the structural features of podocytes and their importance in filtration.

<p>Podocytes have pedicels that create narrow gaps (~40nm) between them, bridged by slit diaphragms, essential for maintaining selective filtration.</p> Signup and view all the answers

How do the characteristics of juxtaglomerular nephrons differ from cortical nephrons?

<p>Juxtaglomerular nephrons have longer loops of Henle that extend deeper into the medulla, allowing for greater urine concentration.</p> Signup and view all the answers

What is the significance of the slit diaphragm in the filtration barrier of the kidney?

<p>The slit diaphragm acts as a loose intercellular connection that restricts the passage of proteins and larger molecules into the urine.</p> Signup and view all the answers

Explain how the afferent and efferent arterioles contribute to glomerular filtration rate (GFR).

<p>Afferent arterioles regulate blood flow into the glomerulus, while efferent arterioles control the outflow, affecting pressure and GFR.</p> Signup and view all the answers

What impact do mesangial cells have on kidney function?

<p>Mesangial cells provide structural support and regulate blood flow within the glomerulus, influencing filtration rate.</p> Signup and view all the answers

How does GFR change when the macula densa detects high sodium and chloride levels?

<p>High levels of sodium and chloride lead to the constriction of the afferent arteriole, resulting in a decrease in GFR.</p> Signup and view all the answers

What is the primary function of the renal cortex in relation to nephron structure?

<p>The renal cortex houses the glomeruli and proximal convoluted tubules, playing a crucial role in filtration and reabsorption.</p> Signup and view all the answers

What is the primary function of densa cells in renal anatomy?

<p>Densa cells help increase the efficiency of transport across membranes in the nephrons.</p> Signup and view all the answers

How do peritubular capillaries differ from the vasa recta?

<p>Peritubular capillaries are primarily associated with cortical nephrons while the vasa recta accompany juxtamedullary nephrons.</p> Signup and view all the answers

Explain how medullary rays relate to nephron collections.

<p>Medullary rays collect urine from a higher number of nephrons, which enhances urine concentration.</p> Signup and view all the answers

What distinguishes juxtamedullary nephrons from cortical nephrons?

<p>Juxtamedullary nephrons extend deeper into the medulla and are important for producing concentrated urine.</p> Signup and view all the answers

Describe the role of proximal convoluted tubules in renal function.

<p>Proximal convoluted tubules reabsorb the majority of filtered water and solutes back into the bloodstream.</p> Signup and view all the answers

Why are medullary rays associated with higher nephron sizes?

<p>Medullary rays increase in size closer to the medulla because they correspond to the collection ducts of multiple nephrons.</p> Signup and view all the answers

What purpose does the structure of densa cells serve in nephron efficiency?

<p>The structure of densa cells enhances the transport efficiency of ions and molecules across membranous barriers.</p> Signup and view all the answers

What cellular characteristics differentiate the proximal convoluted tubule (PCT) from the distal convoluted tubule (DCT)?

<p>The PCT has high amounts of active transport with microvilli, while the DCT has fewer microvilli and more nuclei.</p> Signup and view all the answers

How does the anatomy of the renal tubules contribute to efficiency?

<p>The morphology of the renal tubules, including proximal and distal segments, ensures optimized filtration and reabsorption.</p> Signup and view all the answers

Explain the epithelial characteristics observed in the thin segments of the Loop of Henle.

<p>The thin segments have simple squamous epithelium that facilitates diffusion.</p> Signup and view all the answers

How does aldosterone regulate water permeability in the collecting ducts?

<p>Aldosterone increases aquaporin density, enhancing water reabsorption.</p> Signup and view all the answers

In what way do collecting ducts relate to the function of nephrons?

<p>Collecting ducts function as the final site for urine concentration, collecting filtrate from several nephrons.</p> Signup and view all the answers

Why is the distinction between cortical and juxtamedullary nephrons significant?

<p>This distinction is significant as it dictates the function of each nephron type in urine formation and concentration.</p> Signup and view all the answers

What type of epithelium is found in the ureter, and why is it significant?

<p>The ureter contains rounded stratified squamous epithelium, which protects against stretch.</p> Signup and view all the answers

What role do structural adaptations of nephron segments play in kidney function?

<p>Structural adaptations allow for specialized functions such as filtration, reabsorption, and secretion in different nephron regions.</p> Signup and view all the answers

Identify the primary muscular layers in the ureter and their arrangement.

<p>The muscularis externa comprises an inner circular and an outer longitudinal layer.</p> Signup and view all the answers

What happens during the micturition reflex?

<p>Stretching of the bladder triggers detrusor muscle contraction, leading to the urge to urinate.</p> Signup and view all the answers

How do changes in nephron structure reflect their functional roles?

<p>Changes in nephron structure, like thickness and length, reflect their specific functional roles in filtration and absorption efficiency.</p> Signup and view all the answers

What is the significance of the collecting ducts' directionality?

<p>The directional formation of collecting ducts enhances the efficiency of urine transport to the renal pelvis.</p> Signup and view all the answers

Describe the anatomical relationship of the ureter with the gonadal vessels.

<p>The ureter passes behind the gonadal vessels as it traces its path posteriorly.</p> Signup and view all the answers

What is the role of the detrusor muscle in the bladder?

<p>The detrusor muscle contracts to expel urine from the bladder.</p> Signup and view all the answers

How does the bladder accommodate different volumes of urine?

<p>The bladder contains highly folded mucosa, allowing it to expand as it fills.</p> Signup and view all the answers

What is the significance of the trigone area in the bladder?

<p>The trigone is a smooth area that marks the openings of the ureters and urethra, facilitating urine flow.</p> Signup and view all the answers

Explain the significance of the external and internal urethral sphincters in urination.

<p>The internal sphincter maintains continence, while the external sphincter allows voluntary control over urination.</p> Signup and view all the answers

What is the primary blood supply to the upper ureter?

<p>The upper ureter is primarily supplied by branches from the renal arteries.</p> Signup and view all the answers

Describe the unique histological feature of the bladder compared to the ureter.

<p>The bladder lacks a submucosa, featuring directly folded mucosa over the muscularis layers.</p> Signup and view all the answers

What do the layers of the bladder wall consist of?

<p>The bladder wall consists of mucosa, a thick muscularis external (detrusor), and adventitia.</p> Signup and view all the answers

What is the primary function of the segmental blood supply in the renal segments?

<p>To define surgical boundaries for kidney procedures (B)</p> Signup and view all the answers

Which autonomic pathway results in increased renal arterial flow?

<p>Vagus nerve stimulation (D)</p> Signup and view all the answers

What is the primary impact of sympathetic nerve supply on renal function?

<p>It decreases renal blood flow (A)</p> Signup and view all the answers

Which of the following statements about the autonomic nerve supply to the kidneys is accurate?

<p>Neural regulation of renal blood flow is influenced by hormonal control (D)</p> Signup and view all the answers

Why are fat packs significant at the hilum of the kidney?

<p>They provide structural support for renal blood vessels (A)</p> Signup and view all the answers

Where does the synapse between pre-synaptic and post-synaptic neurons for the kidneys occur?

<p>In the aorta (C)</p> Signup and view all the answers

What is the primary function of the neural activity directed towards the kidneys?

<p>Constrict renal blood vessels (A)</p> Signup and view all the answers

What outcome is expected when blood flow is redirected towards more active tissues?

<p>Enhanced oxygen delivery to muscles (B)</p> Signup and view all the answers

Which statement best describes the relationship between renal blood flow and tissue activity?

<p>Reduced tissue activity leads to increased renal blood flow for waste removal. (D)</p> Signup and view all the answers

What physiological mechanism is involved in the constriction of renal blood vessels?

<p>Norepinephrine release at synapses (D)</p> Signup and view all the answers

Which layer of the glomerulus is responsible for cleaning proteinaceous debris?

<p>Mesangial cells (C)</p> Signup and view all the answers

What primary substance is secreted during the process of urine formation?

<p>Creatinine (D)</p> Signup and view all the answers

What is the essential mechanism for the establishment of a concentration gradient in the Loop of Henle?

<p>Countercurrent flow (B)</p> Signup and view all the answers

Which cells in the juxtaglomerular apparatus respond to blood pressure changes?

<p>Juxtaglomerular cells (B)</p> Signup and view all the answers

What significant filtration feature of the glomerulus allows for selective blood filtration?

<p>Fenestrated capillaries (D)</p> Signup and view all the answers

What are the main components that make up a renal lobe?

<p>Cortex and medullary pyramids (A)</p> Signup and view all the answers

Which part of the nephron is primarily involved in urine concentration?

<p>Loop of Henle (A)</p> Signup and view all the answers

What structure serves as the pathway through which urine passes from the major calyces to the bladder?

<p>Ureter (D)</p> Signup and view all the answers

In renal anatomy, what do the medullary pyramids primarily contain?

<p>Nephrons' long tubules (C)</p> Signup and view all the answers

What structure cups the papilla to collect waste in the kidney?

<p>Minor calyx (D)</p> Signup and view all the answers

Which part of the nephron specifically consists of both proximal and distal elements?

<p>Convoluted tubules (D)</p> Signup and view all the answers

Which component connects the nephrons to the minor calyx?

<p>Collecting ducts (D)</p> Signup and view all the answers

What anatomical feature of the kidney distinguishes the outer layer from the inner medullary tissue?

<p>Cortex (B)</p> Signup and view all the answers

Which structure is formed by the convergence of multiple minor calyces?

<p>Major calyx (A)</p> Signup and view all the answers

What is the primary function of the vasa recta in the kidney?

<p>Transport urea between ductules and interstitial fluid (C)</p> Signup and view all the answers

What is the function of medullary rays in renal anatomy?

<p>Connecting nephrons to collecting ducts (B)</p> Signup and view all the answers

Which mechanism is primarily responsible for the concentration gradient within the renal medulla?

<p>Countercurrent multiplication (A)</p> Signup and view all the answers

The term 'countercurrent multiplication' primarily refers to which anatomical structures in the kidney?

<p>Ascending and descending limbs of the loop of Henle (A)</p> Signup and view all the answers

How does urea contribute to the formation of the medullary concentration gradient?

<p>Is passively reabsorbed in the collecting duct (A)</p> Signup and view all the answers

What structural relationship does the efferent arteriole have in relation to the vasa recta?

<p>It gives rise to the peritubular capillaries (A)</p> Signup and view all the answers

What is primarily detected by the macula densa cells?

<p>Sodium and chloride concentrations (D)</p> Signup and view all the answers

Which structure is identified as bridging the gaps between podocyte pedicels?

<p>Slit diaphragm (A)</p> Signup and view all the answers

What happens when the macula densa detects low sodium and chloride flow?

<p>Decreased GFR and increased renin secretion (B)</p> Signup and view all the answers

Which type of nephron primarily concentrates urine by having longer loops of Henle?

<p>Juxtamedullary nephrons (D)</p> Signup and view all the answers

What is the approximate size of the gaps between podocyte pedicels?

<p>40 nm (B)</p> Signup and view all the answers

In which location is the juxtaglomerular nephron primarily found?

<p>At the junction of the cortex and medulla (A)</p> Signup and view all the answers

The structure of the afferent and efferent arterioles affects which renal function?

<p>Glomerular filtration rate (GFR) (B)</p> Signup and view all the answers

Which cell type is not directly involved in the filtration barrier of the glomerulus?

<p>Macula densa (C)</p> Signup and view all the answers

What anatomical structure is primarily responsible for transporting urine from the mesonephros to the cloaca?

<p>Mesonephric duct (B)</p> Signup and view all the answers

During what week of embryonic development does the mesonephros appear?

<p>Week 4 (B)</p> Signup and view all the answers

Which of the following statements correctly describes the mesonephros compared to the pronephros?

<p>The mesonephros has a smaller glomerulus and larger tubular network. (C)</p> Signup and view all the answers

What is the fate of the thoracic nephrotomes in the development of the mesonephros?

<p>They regress after the development of the mesonephros. (D)</p> Signup and view all the answers

What anatomical feature grows from the dorsal side of the pelvic mesonephric duct during mesonephros development?

<p>Metanephric ducts (C)</p> Signup and view all the answers

What is the primary reason for the mesonephros being referred to as the 'middle' kidney in evolutionary terms?

<p>It suggests a transitional stage between two forms of kidney evolution. (A)</p> Signup and view all the answers

What is the significance of the signalling mechanism in kidney development?

<p>It regulates the growth sequence from cranial to caudal end. (D)</p> Signup and view all the answers

Which of the following adaptations helps organisms face the reverse osmotic challenge when transitioning from sea to land?

<p>Enhanced selective processes for reclaiming water in the body. (A)</p> Signup and view all the answers

How does the linear evolution of the kidneys relate to land habitats?

<p>It shows a direct adaptation of structures to terrestrial challenges. (B)</p> Signup and view all the answers

What role does preadaptation play in the transition of species returning to the sea?

<p>It supports adaptations needed for varying levels of osmotic pressure. (C)</p> Signup and view all the answers

What is the order of kidney development in vertebrates from the earliest to the latest stage?

<p>Pronephros, Mesonephros, Metanephros (B)</p> Signup and view all the answers

In which anatomical region does the pronephros primarily develop?

<p>Cervical region (B)</p> Signup and view all the answers

What function do nephrotomes serve in kidney development?

<p>They are the primitive components leading to the formation of the kidney. (A)</p> Signup and view all the answers

What role does the intermediate mesoderm play during renal ontogeny?

<p>It forms the urogenital ridge. (C)</p> Signup and view all the answers

Which kidney type is associated with the thoracic to lumbar region development?

<p>Mesonephros (B)</p> Signup and view all the answers

How many distinct types of kidneys develop from the nephric tissues?

<p>Three (A)</p> Signup and view all the answers

What anatomical structure does the adult adrenal gland derive from?

<p>Lateral plate mesoderm (B)</p> Signup and view all the answers

Which aspect of kidney development is primarily influenced by evolutionary pressures?

<p>The ascent to the final anatomical position (A)</p> Signup and view all the answers

Which structure surrounds the kidney itself within the renal fascia?

<p>Perirenal fat (B)</p> Signup and view all the answers

What is the anatomical position of the upper poles of the kidney relative to the diaphragm?

<p>At the same level as the diaphragm (A)</p> Signup and view all the answers

Which muscles is the kidney maximally associated with in terms of its positioning?

<p>Psoas (A)</p> Signup and view all the answers

Which layer of fat encapsulates the kidney but is located outside the renal fascia?

<p>Pararenal fat (C)</p> Signup and view all the answers

Which ribs are associated with the seating of the upper poles of the kidneys?

<p>Ribs 11 and 12 (D)</p> Signup and view all the answers

What condition occurs when a kidney fails to ascend during development?

<p>Pelvic kidney (D)</p> Signup and view all the answers

What anatomical feature is characterized by kidneys joining together in the pelvic region?

<p>Horseshoe kidney (B)</p> Signup and view all the answers

During kidney development, what happens to the blood supply as the kidneys ascend?

<p>They acquire new paired arteries and lose lower ones (B)</p> Signup and view all the answers

How many renal arteries can be normal for a kidney during its development?

<p>Up to four (B)</p> Signup and view all the answers

What aspect of the subcardinal venous system is described as 'ladder-like' during development?

<p>Structural appearance of venous connections (D)</p> Signup and view all the answers

What does it indicate if the metanephric kidneys become attached in the pelvis?

<p>Horseshoe kidney formation (D)</p> Signup and view all the answers

What is typically associated with the renal pelvis in terms of development?

<p>It forms from bifurcating minor calyces (A)</p> Signup and view all the answers

What happens to the lower renal vessel as the kidneys ascend?

<p>It becomes redundant and drops away (B)</p> Signup and view all the answers

What does the Y-shaped formation during renal development refer to?

<p>Connection of minor calyces (C)</p> Signup and view all the answers

What could be a consequence if the renal arteries exhibit accessory formations?

<p>Increased risk of renal obstruction (C)</p> Signup and view all the answers

What anatomical structure originates from the mesonephric ducts during urogenital development?

<p>Urethra (A)</p> Signup and view all the answers

At which week of gestation does the anal canal, vagina, and urethra first become present?

<p>12th week (A)</p> Signup and view all the answers

What is the significance of the allantois in relation to the bladder?

<p>It transitions into the umbilicus. (A)</p> Signup and view all the answers

What developmental process occurs during the 6th week regarding the cloaca?

<p>Division of the cloaca (B)</p> Signup and view all the answers

What complication is indicated by stagnant urine in cases of unclosed allantois?

<p>Urinary tract infections (UTIs) (D)</p> Signup and view all the answers

Why is it important to recognize the hindgut origin of the bladder?

<p>Relevance in surgical procedures (C)</p> Signup and view all the answers

Which embryological structure does the primordial bladder derive from?

<p>Allantois (D)</p> Signup and view all the answers

What occurs during the ascent of the kidneys in relation to metanephric ducts?

<p>They ascend dorso-cranially. (C)</p> Signup and view all the answers

What role does signalling play in kidney development according to the provided content?

<p>Signalling is essential for the sequential development of kidneys, moving from the cranial to the caudal end.</p> Signup and view all the answers

In the context of phylogeny, what significance does the mesonephros hold?

<p>The mesonephros is referred to as the 'middle' kidney and demonstrates evolutionary adaptations towards land life.</p> Signup and view all the answers

What adaptive challenge do fish face when transitioning back to sea from land?

<p>Fish encounter reverse osmotic challenges due to lower salt and water concentrations in air compared to their body fluids.</p> Signup and view all the answers

How does the structure of the kidney help in managing osmotic pressure?

<p>A tubular network connects directly with the mesonephric duct, acting as a selective filter for reabsorbing necessary nutrients.</p> Signup and view all the answers

What is meant by ‘preadaptation’ in relation to fish returning to life on land?

<p>Preadaptation refers to evolutionary traits that facilitate the transition from water to land, addressing challenges like water loss.</p> Signup and view all the answers

What anatomical structures are involved in the crossing of left paired glands to the right side?

<p>The left paired glands cross to the right side via the subcardinal anastomosis.</p> Signup and view all the answers

Describe the embryological origin of the bladder lining.

<p>The lining of the bladder is primarily derived from the hindgut, specifically the cloaca.</p> Signup and view all the answers

What characteristic appearance do subcardinal veins exhibit during development?

<p>Subcardinal veins appear 'ladder-like' due to the anastomoses between the left and right vasculature.</p> Signup and view all the answers

How does the anatomy of the renal veins differ on the left compared to the right side?

<p>The left renal vein has a longer course due to crossing over to join the inferior vena cava, while the right renal vein does not need to cross much distance.</p> Signup and view all the answers

What is the primary function of the trigone in the bladder?

<p>The trigone serves as the internal area for ureter input and urethral output.</p> Signup and view all the answers

What anatomical feature explains why the left renal vein is longer than the right?

<p>It crosses anterior to the aorta to connect to the inferior vena cava.</p> Signup and view all the answers

What is the primary reason for the difference in the vertical positioning of the left and right kidneys?

<p>The liver on the right side pushes the right kidney lower than the left.</p> Signup and view all the answers

How does the anatomical location of the hilum relate to kidney function?

<p>The hilum allows for the entry and exit of blood vessels and ureters, crucial for kidney function.</p> Signup and view all the answers

During respiration, how do the kidneys' positions change?

<p>The kidneys move slightly with the diaphragm's movement, adapting to changes in thoracic pressure.</p> Signup and view all the answers

In terms of vascular anatomy, why is it significant that the renal vein is positioned anteriorly to the renal artery?

<p>It allows for efficient drainage of deoxygenated blood while maintaining the supply of oxygenated blood.</p> Signup and view all the answers

What is a pelvic kidney?

<p>A pelvic kidney is a condition where a kidney fails to ascend to its normal position in the abdominal cavity during development.</p> Signup and view all the answers

Describe horseshoe kidney formation.

<p>Horseshoe kidney occurs when both kidneys join together at their lower poles and cannot ascend due to their attachment.</p> Signup and view all the answers

What happens to renal arteries during kidney ascent?

<p>As the kidneys ascend, they acquire new paired branches while dropping the lower renal arteries.</p> Signup and view all the answers

What is the subcardinal venous system's appearance during development?

<p>The subcardinal venous system appears 'ladder-like' in configuration as it develops.</p> Signup and view all the answers

What are accessory renal arteries?

<p>Accessory renal arteries are additional arteries that may form and supply blood to the kidneys during development.</p> Signup and view all the answers

How many major calyces can form during kidney development?

<p>Multiple major calyces can form, and their number may vary based on the normal developmental process.</p> Signup and view all the answers

What does it indicate if kidneys are not bilaterally symmetrical?

<p>Bilateral asymmetry can suggest developmental anomalies such as renal agenesis or ectopic kidneys.</p> Signup and view all the answers

What is the relationship between ureters and major calyces?

<p>Ureters arise from the renal pelvis, which collects urine from the major calyces.</p> Signup and view all the answers

What two structures can come from the bifurcation of a renal artery?

<p>A bifurcated renal artery can rejoin or form accessory arteries supplying different parts of the kidney.</p> Signup and view all the answers

Why is the left renal vein longer than the right renal vein?

<p>The left renal vein is longer because it crosses in front of the aorta to drain into the inferior vena cava.</p> Signup and view all the answers

What is the role of the subcardinal system in venous development?

<p>The subcardinal system repurposes and connects veins from the left side to the right, contributing to venous return.</p> Signup and view all the answers

How does the position of the kidneys relate to the adrenal glands during development?

<p>The kidneys sit just below the adrenal glands, affecting their vascular connections and drainage pathways.</p> Signup and view all the answers

What anatomical change occurs to the cardinal veins during development?

<p>The original cardinal veins obliterate and are replaced by the subcardinal veins in the trunk.</p> Signup and view all the answers

What is indicated by the term 'anastomosis' in relation to the subcardinal system?

<p>Anastomosis refers to the connections formed between the left and right subcardinal veins during development.</p> Signup and view all the answers

Explain the significance of the ventral orientation in the embryonic cardiovascular system.

<p>Ventral orientation is significant as it determines the positioning and development of the subcardinal and cardinal systems.</p> Signup and view all the answers

What implications does having a longer left renal vein have for vascular complications?

<p>A longer left renal vein may predispose individuals to certain vascular complications, such as renal vein thrombosis.</p> Signup and view all the answers

Describe how the kidney's drainage system is adapted during development.

<p>The kidney's drainage system is adapted by forming a ladder-like structure to facilitate the movement of urine during its ascent.</p> Signup and view all the answers

What developmental structure becomes the bladder and is associated with the allantois?

<p>The bladder develops from the allantois.</p> Signup and view all the answers

At what week do the anal canal, vagina, and urethra become present in fetal development?

<p>These structures become present at the 12th week.</p> Signup and view all the answers

What embryonic structure forms the septum that divides the cloaca?

<p>The septum forms in the 6th week of development.</p> Signup and view all the answers

What is a potential consequence of an unclosed allantois during fetal development?

<p>An unclosed allantois can lead to urinary tract infections due to stagnant urine.</p> Signup and view all the answers

What is the significance of recognizing the hind gut's origin in relation to the bladder?

<p>Recognizing the hind gut origin helps understand the anatomical relationships and potential malformations of the bladder.</p> Signup and view all the answers

During what embryonic stage do the mesonephric ducts contribute to the urogenital sinus?

<p>The mesonephric ducts contribute during the early stages of kidney development.</p> Signup and view all the answers

What anatomical change occurs to the kidneys during fetal development?

<p>The kidneys ascend dorso-cranially during development.</p> Signup and view all the answers

What anatomical remnant indicates where the allantois connected to the umbilicus?

<p>The remnant is a fibrous ligament at the apex of the bladder.</p> Signup and view all the answers

What structures create the four anatomical lobes of the liver?

<p>Falciform ligament and coronary ligament (A), Quadrate lobe and caudate lobe impressions (B)</p> Signup and view all the answers

Which ligament is specifically formed from the left coronary ligament?

<p>Lesser omentum (C), Triangular ligament (D)</p> Signup and view all the answers

How is the caudate lobe of the liver differentiated in relation to the inferior vena cava (IVC)?

<p>It is formed from the gallbladder impression (A), It is bordered by the IVC and the right coronary ligament (C)</p> Signup and view all the answers

What is the primary function of the coronary ligament in the liver?

<p>Anchoring the liver to the diaphragm (C), Separating left and right anatomical lobes (D)</p> Signup and view all the answers

Which features are primarily responsible for identifying the liver lobules in histological sections?

<p>Portal triads and central veins (C), Bile canaliculi and portal venules (D)</p> Signup and view all the answers

What role does the ligamentum teres play in the anatomy of the liver?

<p>Serves as an attachment from the liver to the anterior body wall (A), Marks the fissure between the quadrate lobe and the left lobe (B)</p> Signup and view all the answers

What developmental origin is associated with the hepatic diverticulum?

<p>Mesodermal layer (C), Endodermal layer (D)</p> Signup and view all the answers

What anatomical structure is associated with the gallbladder impression on the liver?

<p>Quadrate lobe (B), Bare area (C)</p> Signup and view all the answers

Which functional segments of the liver are defined by the portal triads?

<p>Left, Right, Caudate, and Quadrate lobes (C)</p> Signup and view all the answers

What is the primary difference in blood and bile flow direction in the liver?

<p>Bile flows towards the central vein while blood flows towards the portal triads (B)</p> Signup and view all the answers

Which zone in the liver acinus is the first to show ischemic necrosis?

<p>Zone 3 (D)</p> Signup and view all the answers

Which component is NOT part of the biliary system?

<p>Superior mesenteric artery (B)</p> Signup and view all the answers

What is the primary role of Kupffer cells in the liver?

<p>Act as macrophages in the liver (B)</p> Signup and view all the answers

Which structure is primarily responsible for bile drainage to the duodenum?

<p>Common bile duct (C)</p> Signup and view all the answers

How is the histological composition of the gallbladder primarily characterized?

<p>Simple columnar epithelium with microvilli (B)</p> Signup and view all the answers

What type of cells are primarily responsible for the liver's regenerative capacity?

<p>Hepatocytes (C)</p> Signup and view all the answers

What distinguishes the 'portal lobule' concept from the 'classical lobule' concept?

<p>Classical lobule defines drainage to a central triad (D)</p> Signup and view all the answers

Which statement about the liver capsule is true?

<p>It provides external support and has its own blood supply (A)</p> Signup and view all the answers

What mechanism allows the gallbladder to empty its contents?

<p>Smooth muscle contraction (B)</p> Signup and view all the answers

Where are sinusoidal capillaries primarily located in the liver?

<p>Between plates of hepatocytes (D)</p> Signup and view all the answers

What is the main role of the perisinusoidal space (of Disse)?

<p>Facilitate oxygen exchange between blood and hepatocytes (B)</p> Signup and view all the answers

How is the exocrine pancreas structured?

<p>Formed by lobules with serous secretory units (C)</p> Signup and view all the answers

Why is the left renal vein longer than the right renal vein?

<p>The left renal vein is longer because it must cross in front of the aorta to reach the right side where the inferior vena cava is located.</p> Signup and view all the answers

What anatomical structure affects the position of the kidneys in relation to each other?

<p>The liver affects the position of the right kidney, causing it to sit lower than the left kidney.</p> Signup and view all the answers

What are the relationships of the structures at the renal hilum?

<p>At the renal hilum, the renal vein is most anterior, followed by the renal artery and then the ureter.</p> Signup and view all the answers

At what lumbar vertebral levels are the kidneys typically located?

<p>The kidneys are typically located around the L1 to L2 vertebral levels.</p> Signup and view all the answers

How does breathing affect the position of the kidneys?

<p>The kidneys move about slightly with the diaphragm during breathing.</p> Signup and view all the answers

What are the three stages of kidney development in humans and their corresponding regions?

<p>Pronephros in the cervical region, mesonephros in the thoracic/lumbar region, and metanephros which ascends to its final position.</p> Signup and view all the answers

Discuss the significance of the ascent of the metanephric kidney in human development.

<p>The ascent of the metanephric kidney allows it to achieve optimal anatomical relations and functionality, adapting to the changing body as development progresses.</p> Signup and view all the answers

Explain the role of nephrotomes in kidney development.

<p>Nephrotomes are segmented components of the intermediate mesoderm that give rise to the primitive structures necessary for kidney formation.</p> Signup and view all the answers

What structure develops into the adult kidney from the metanephros?

<p>The metanephros develops into the adult kidney.</p> Signup and view all the answers

Describe the evolutionary pressures that have influenced renal ontogeny in vertebrates.

<p>Evolutionary pressures related to environmental challenges have driven the transition from simple to complex kidney structures, enhancing salt and water regulation.</p> Signup and view all the answers

What is the process of cloacal septation and why is it important for the bladder's trigone?

<p>Cloacal septation divides the cloaca into the rectum and urinary bladder, aiding in the proper development of the bladder's trigone, which is essential for urinary function.</p> Signup and view all the answers

Which type of fish primarily exhibits pronephros as the first kidney type?

<p>Pronephros is primarily found in primitive freshwater fish like lampreys.</p> Signup and view all the answers

How does the pronephros handle excess water in the body?

<p>It filters excess water into the coelomic cavity, which drains into the cloaca.</p> Signup and view all the answers

How does the structure of the pronephros differ from that of the metanephros?

<p>The pronephros is rudimentary and primarily functional in early embryonic development, while the metanephros is a fully developed organ that persists postnatally.</p> Signup and view all the answers

What environmental challenge does the pronephros address for freshwater fish?

<p>The pronephros addresses the challenge of the body's salt concentration being higher than that of the surrounding water.</p> Signup and view all the answers

In what ways does the differentiation of the intermediate mesoderm contribute to kidney development?

<p>The differentiation of the intermediate mesoderm into nephrotomes is crucial for establishing the various kidney stages, influencing both structure and function.</p> Signup and view all the answers

What anatomical relations must be considered during the ascent of the metanephric kidney?

<p>During ascent, the metanephric kidney must navigate surrounding structures like the adrenal glands and renal vessels, impacting its final position in the abdomen.</p> Signup and view all the answers

What is the anatomical origin of the human pronephros?

<p>The human pronephros is derived from cervical nephrotomes.</p> Signup and view all the answers

What role does the glomerulus play in the functioning of pronephros?

<p>The glomerulus allows for selective osmotic control of plasma.</p> Signup and view all the answers

What is the evolutionary significance of the appearance of each type of kidney?

<p>The appearance of each kidney type recapitulates vertebrate evolution.</p> Signup and view all the answers

Why is it significant that complex systems like the kidney reduce developmental errors?

<p>Complex systems like the kidney minimize developmental errors by utilizing copycat structures from evolution.</p> Signup and view all the answers

What result occurs from the osmotic control in cases of freshwater adaptation?

<p>The result is the elimination of excess water from the body.</p> Signup and view all the answers

How does the position of the pronephros change during development?

<p>The pronephros originates in the cervical area and is transitory, lasting only for about two days.</p> Signup and view all the answers

What is the primary role of the metanephric duct during kidney development?

<p>The metanephric duct induces the formation of the metanephric blastema, which leads to the development of glomeruli and nephron tubules.</p> Signup and view all the answers

How does the production of metanephric urine relate to amniotic fluid?

<p>Metanephric urine contributes to the volume of amniotic fluid, which is essential for fetal development and lung function.</p> Signup and view all the answers

What anatomical changes occur to the kidneys during their ascent in fetal development?

<p>The metanephric kidneys ascend cranially while the mesonephros regresses, altering the position of the kidneys relative to the gonads.</p> Signup and view all the answers

What indicates healthy kidney function concerning amniotic fluid?

<p>A healthy amount of amniotic fluid suggests that the fetal kidneys are functioning properly and filtering blood.</p> Signup and view all the answers

In what week of gestation does the ascent of the metanephric kidneys begin?

<p>The ascent of the metanephric kidneys begins around week 6 of gestation.</p> Signup and view all the answers

What structural formations arise from the repeated bifurcation of the metanephric duct?

<p>The bifurcation of the metanephric duct leads to the formation of collecting ducts, calyces, and ultimately the renal pelvis.</p> Signup and view all the answers

What relevance does the timing of fetal kidney ascent have concerning adjacent structures?

<p>The ascent of fetal kidneys occurs concurrently with the regression of the mesonephros and positional changes of the gonads.</p> Signup and view all the answers

Describe the relationship between metanephric urine production and the placenta.

<p>The placenta takes over waste excretion, while metanephric urine is produced to help maintain amniotic fluid volume.</p> Signup and view all the answers

What anatomical relationship causes the left renal vein to be longer than the right renal vein?

<p>The left renal vein is longer because it crosses in front of the aorta to drain into the inferior vena cava.</p> Signup and view all the answers

Explain how the subcardinal system is repurposed in human anatomy.

<p>The subcardinal veins are repurposed from the left side and brought over to the right side in the development of the venous system.</p> Signup and view all the answers

Describe the general orientation of the renal veins in relation to the aorta.

<p>The left renal vein passes in front of the aorta, while the right renal vein is positioned directly more laterally.</p> Signup and view all the answers

What does the term 'ventral' refer to in the context of organ placement?

<p>In anatomy, 'ventral' refers to the front or belly side of the body, indicating the orientation of certain structures.</p> Signup and view all the answers

Identify one reason why the subcardinal system is considered an anastomosis.

<p>The subcardinal system is considered an anastomosis because it connects different venous pathways between the left and right sides.</p> Signup and view all the answers

How do the supra-cardinal and subcardinal systems differ in their anatomical roles?

<p>The supra-cardinal system primarily drains the upper body, while the subcardinal system is involved in draining the lower body structures.</p> Signup and view all the answers

What embryological process influences the final position of the kidneys relative to the adrenal glands?

<p>During development, the kidneys migrate downward, positioning themselves under the adrenal glands due to temporal changes in anatomy.</p> Signup and view all the answers

What anatomical feature does the term 'dorsal' describe in contrast to 'ventral'?

<p>'Dorsal' describes the back side of the body, contrasting with 'ventral,' which refers to the front or stomach side.</p> Signup and view all the answers

How do the subcardinal veins contribute to the development of the inferior vena cava (IVC)?

<p>The subcardinal veins join together via anastomoses, obliterating mostly on the left side, which leads to the formation of the IVC on the right side.</p> Signup and view all the answers

What is the anatomical significance of the trigone area in the bladder?

<p>The trigone serves as the internal area where the ureters input urine into the bladder and the urethra facilitates its output.</p> Signup and view all the answers

Describe the pathway taken by the left adrenal and gonadal veins.

<p>The left adrenal and gonadal veins cross to the right side and join the left renal vein due to the embryological development of the venous system.</p> Signup and view all the answers

What embryological origin does the bladder lining derive from, and how is it positioned in males?

<p>The bladder lining is primarily derived from the hindgut (cloaca) and is positioned on the dorsal side of the body in males.</p> Signup and view all the answers

Explain the implications of left paired glands crossing to the right side via subcardinal anastomosis.

<p>The crossing of left paired glands to the right side via subcardinal anastomosis showcases the dynamic nature of vascular development and its contribution to anatomical asymmetry.</p> Signup and view all the answers

Which ligaments are primarily responsible for connecting the liver to the anterior body wall?

<p>Coronary ligament (B), Falciform ligament (D)</p> Signup and view all the answers

What anatomical structures create the four lobes of the liver?

<p>Ligamentum teres and gallbladder impression (A), Falciform ligament and right triangular ligament (B)</p> Signup and view all the answers

Which statement correctly represents the relationship between the anatomical and functional lobes of the liver?

<p>Anatomical lobes are based on the external surface, while functional lobes are defined by blood supply. (B)</p> Signup and view all the answers

Which ligaments contribute to the formation of the lesser omentum?

<p>Left triangular ligament (B), Right coronary ligament (C)</p> Signup and view all the answers

How does the caudate lobe of the liver get created?

<p>From the IVC (Inferior Vena Cava) impression (A)</p> Signup and view all the answers

Which structure plays a role in connecting the stomach and liver?

<p>Coronary ligament (A), Lesser omentum (C)</p> Signup and view all the answers

What determines the features of the liver, gallbladder, and pancreas in histological sections?

<p>The presence of specific cell types (B), The vascular supply they receive (D)</p> Signup and view all the answers

What is the primary significance of ligaments such as the right coronary ligament in liver anatomy?

<p>Providing structural support for the liver (A), Connecting the liver to the diaphragm (B)</p> Signup and view all the answers

Which liver zone is closest to the hepatic arterioles and demonstrates the first signs of regeneration?

<p>Zone 1 (C)</p> Signup and view all the answers

What is the primary role of the hepatic capsule?

<p>To provide external support and shape to the liver (A)</p> Signup and view all the answers

Which anatomical component is primarily concerned with venous drainage in the liver lobule concept?

<p>Classical lobule (D)</p> Signup and view all the answers

What type of epithelium lines the bile ducts found in the portal triads?

<p>Simple cuboidal epithelium (A)</p> Signup and view all the answers

Which component primarily delivers bile into the duodenum?

<p>Common bile duct (D)</p> Signup and view all the answers

Which structure is characterized by sinusoids that allow direct contact between hepatocytes and blood?

<p>Lobule (C)</p> Signup and view all the answers

What is the main function of hepatocytes in the liver?

<p>Secretion of bile (B)</p> Signup and view all the answers

What defines the 'portal lobule' concept in liver anatomy?

<p>Flow to and from a centralised triad (D)</p> Signup and view all the answers

Why does the liver have a jelly-like consistency?

<p>Because of high water content (C)</p> Signup and view all the answers

What cells in the liver play a critical role in regeneration and vitamin A storage?

<p>Stellate cells (D)</p> Signup and view all the answers

Which of the following structures is primarily involved in concentrating bile?

<p>Gallbladder (A)</p> Signup and view all the answers

In the histology of the exocrine pancreas, which cells line the first portion of the duct system?

<p>Centroacinar cells (D)</p> Signup and view all the answers

What is the primary role of Kupffer cells in the liver?

<p>Phagocytosis of pathogens (C)</p> Signup and view all the answers

Which of the following best describes the vascular layout of the classical lobule?

<p>One portal triad and one central vein (C)</p> Signup and view all the answers

In the gallbladder histology, which feature aids in water reabsorption?

<p>Simple columnar epithelium with microvilli (D)</p> Signup and view all the answers

Flashcards

Cloacal Septation

The division of the cloaca (a common opening) into separate openings for the urinary, reproductive, and digestive tracts.

Rectovesical Pouch

A space between the rectum and bladder, where fluid can collect (in males).

Parietal Peritoneum

The lining of the abdominal wall and pelvic cavity.

Male Reproductive Tract Orientation

The male reproductive tract aligns with the pelvic inlet orientation.

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Female Reproductive Tract Orientation

The female reproductive tract is flanked by recesses of peritoneum, overlying the bladder and uterus.

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Pelvic Viscera Orientation

Describes the arrangement of organs within the pelvis, considering differences between males and females.

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Peritoneal Pouches/Mesenteries

The folds of the peritoneum (membrane lining the abdominal cavity) within the pelvis, which vary in males and females.

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Rectum & Anus

The terminal portion of the digestive tract and its opening. Structure varies in orientation and relationship to pelvic floor.

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Reproductive Tracts

Organs in the pelvis involved in reproduction (ovaries, uterus, fallopian tubes in females; testes, epididymis, vas deferens in males).

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Blood/Nerve/Lymphatics

The blood vessels, nerves, and lymphatic vessels that supply and drain the pelvic organs, including arteries, veins and nerves.

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Fetal-Maternal Interface

The placenta, which facilitates exchange of materials between mother and developing fetus.

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Pelvic Inlet

The opening into the pelvis; angles differently in males and females.

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Rectal Curve

Rectum's curvature in the pelvis.

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Fetal-maternal interface

The area where fetal and maternal blood come close to each other, but do not mix directly, enabling exchange of substances.

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Chorionic plate

Fetal villi with syncytiotrophoblast epithelium. Critical for fetal-maternal blood barrier and exchange.

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Basal plate

Maternal side of the placenta where spiral arteries open into intervillous space. Site for gas, waste, and hormone exchange.

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Spiral arteries

Maternal arteries that open into the intervillous space in the placenta.

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Hypogastric nerve

Sympathetic nerve pathway for male autonomic functions supplying the pelvic region.

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Pelvic splanchnic nerves

Parasympathetic nerves that aid in male pelvic functions.

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Autonomic nerve supply (male)

Complex interplay of sympathetic (hypogastric) and parasympathetic (pelvic splanchnic) nerves in the male pelvis.

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Fetal-maternal blood barrier

Specialized structure preventing direct mixing of fetal and maternal blood, crucial for safe exchange.

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Uterus Anteflexion

The uterus curves forward over the bladder.

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Uterine Expansion

The uterus can expand into the abdomen due to pouches.

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Vagina Orientation

The vagina is positioned generally parallel to the pelvic brim, close to the posterior wall of urethra and bladder trigone.

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Broad Ligament

A peritoneal sheet that drapes over the uterine tubes and supports expansion of the uterus.

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Mesosalpinx

Part of the broad ligament that supports the uterine tubes.

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Mesovarium

Part of the broad ligament supporting the ovary.

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Mesometrium

Part of the broad ligament supporting the uterus.

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Ovary Position

The ovary is suspended slightly above the uterus, and is visible from a posterior view.

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Uterosacral Ligaments

Ligaments connecting the uterus to the sacrum, providing stability.

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Cardinal Ligaments

Ligaments supporting the cervix and uterus.

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Round Ligament

Connects the uterus to the labia majora through the inguinal canal.

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Uterine Artery

Branch of the internal iliac artery that supplies the uterus.

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Internal Iliac Artery Branches

Several arteries branching off from the internal iliac artery, supplying pelvic organs.

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Umbilical Artery

A branch of the abdominal aorta, part of the fetal circulatory system.

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Obturator Artery

Supplies blood to the muscles and tissues around the obturator foramen.

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Anterior Pelvic Structures

Includes the bladder, portions of the reproductive tracts (ovaries, uterus), and associated ligaments.

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Uterovesical Pouch

The pouch formed by the bladder and uterus.

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Rectouterine Pouch (of Douglas)

The pouch formed by the uterus and rectum; a potential space.

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Rectum vs. Colon

The rectum lacks taenia coli, having a continuous longitudinal smooth muscle layer, which is visible in the lab.

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Pararectal fossae

The spaces in the upper third of the rectum, continuous with the peritoneal cavity.

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Rectovesical/Rectouterine Pouch (middle third)

The pouch located in the middle third of the rectum, containing organs specific to either males (prostate) or females (uterus).

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Bladder structure

Smooth muscle sac lined by transitional epithelial tissue, mostly derived from hindgut.

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Trigone (bladder)

Internal bladder region where ureters enter and urethra exits.

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Clinical significance of pouches

Fluid accumulation, surgical access, and anatomical relationships are impacted by these pouches.

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Pelvic Viscera Orientation

Arrangement of organs within the pelvis; differs between males and females.

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Pelvic Inlet Angle

The angle of the opening into the pelvis; differs between male and female.

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Rectal Curve

The curvature of the rectum within the pelvis.

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Peritoneal Pouches/Mesenteries

Folds of peritoneum within the pelvis, varying in males and females.

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Fetal-Maternal Interface

Structure enabling exchange between fetal and maternal blood.

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Blood/Nerve/Lymphatics (Pelvic)

Blood vessels, nerves, and lymphatic vessels serving pelvic organs.

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Reproductive Tracts (Male/Female)

Organs involved in reproduction within the pelvis, differing in males & females.

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Rectum and Anus

Terminal portion of digestive tract; varies structurally and relation to pelvic floor.

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Ovarian blood supply

Blood vessels that supply the ovary, originating from the abdominal aorta.

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Suspensory ligament

Connective tissue that anchors the ovary to the pelvic wall.

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Uterine blood supply

The network of blood vessels feeding the uterus.

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Arcuate arteries

Blood vessels that arch around the uterus.

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Radial arteries

Blood vessels branching out from arcuate arteries.

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Spiral arteries

Blood vessels with a spiral-like pattern in the uterus.

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Anastomosis

Union of two blood vessels.

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Ovarian artery route

Travels via the suspensory ligament.

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Uterovesical Pouch

The space created by the bladder and uterus.

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Rectouterine Pouch (of Douglas)

A pouch between the rectum and uterus. Can collect fluid in females.

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Rectum vs. Colon

The rectum lacks taenia coli (bands of muscle) and has a continuous layer of smooth muscle.

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Pararectal Fossae

Spaces in the upper third of the rectum, open to the peritoneal cavity.

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Rectovesical/Rectouterine Pouch

Pouch between the rectum and bladder/uterus, in the middle third of the rectum.

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Bladder Structure

A smooth muscle sac lined by special tissue (transitional epithelium), mostly from the hindgut.

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Bladder Trigone

The internal part of the bladder where ureters enter and urethra exits.

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Clinical Significance of Pouches

Fluid collection, surgical procedures, and anatomical relations are affected by these pouches.

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Penis Structure

The male external genitalia, comprised of the corpora cavernosa and corpus spongiosum, with tunica albuginea and fibrous tissue.

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Corpora Cavernosa

Paired erectile tissues in the penis, responsible for most of the penis's enlargement during erection, supported by fibrous tissue.

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Corpus Spongiosum

Erectile tissue surrounding the urethra in the penis, maintaining urethral patency during erection.

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Tunica Albuginea

A tough fibrous sheath surrounding the corpora cavernosa, providing structural support.

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Uterus Orientation

The uterus is anteverted, meaning it tilts forward over the vagina.

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Anteverted Cervix

The cervix tilts forward relative to the vagina.

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Erection Mechanism

Increased blood flow to the corpora cavernosa, causing them to expand and stiffen.

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Cervix Fornices

Spaces surrounding the cervix in the vagina, formed by the position of the cervix.

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Parasympathetic Nerve Supply (Female Pelvis)

Female pelvic organs are innervated by pelvic splanchnic nerves, part of the parasympathetic nervous system.

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Myometrium Innervation

The myometrium (uterine muscle) is primarily controlled by the endocrine system, not the autonomic nervous system.

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Lymphatic Drainage (Gonads)

Lymphatic drainage from gonads follows the gonadal vessels to specific regional lymph nodes.

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Pelvic Viscera Lymph Nodes

Pelvic viscera's lymphatic drainage typically flows through internal iliac nodes then to lateral and pre-aortic lumbar nodes.

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Lymphatic Drainage (Perineum)

Deep perineal structures drain to internal iliac nodes, while superficial structures drain to inguinal nodes, then to external iliac, and then internal iliac nodes.

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Urogenital Sinus Mesoderm

The embryonic tissue that gives rise to the urethra, anal canal, and vagina.

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Cloaca Division (6th week)

The partitioning of the cloaca, a single embryonic opening, into separate openings for the urinary, reproductive, and digestive tracts.

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Urinary Tract (12th week)

The time frame in fetal development when the definitive urinary tract (including the urethra, and other structures) starts to form after the mesonephric kidney has gone

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Triangular Pyramid of the Bladder

The triangular region on the interior of the bladder where the ureters enter and the urethra exits.

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Bladder Surfaces

The four surfaces of the bladder, including two lateral (against pubic bones), one superior (covered in peritoneum), and one posterior (receiving ureters).

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Bladder Points

The four points of the bladder, including two lateral (origin receiving ureters), one inferior ('neck' region, urethra exit), and one superior ('apex', containing the urachus within the median umbilical ligament).

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Ductus Deferens

The tube that carries sperm from the epididymis to the ejaculatory duct.

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Ejaculatory Ducts

The ducts formed by the union of the vas deferens and seminal vesicles.

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Prostate Gland

A gland in the male reproductive system that surrounds the urethra at the base of the bladder and secretes fluids into the semen.

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Metanephric Duct

The embryonic duct that gives rise to the renal pelvis and ureter.

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Proliferative (oestradiol)

Nourishes early fetus through diffusion using uterine milk.

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Uterine Milk

Substance secreted by uterine glands to nourish the embryo.

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Cervix Function

Holds the baby in and regulates sperm transport via endocervical canal, lined by simple columnar epithelium.

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Ectocervix

External part of cervix, exposed to vagina, secretion depends on hormones.

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Vaginal Epithelium

Stratified squamous epithelium, high in glycogen (oestrogen), broken down by bacteria for pH regulation.

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Vaginal Rugae

Folds in the vagina allowing distention during intercourse and childbirth.

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Testis Tunica Vaginalis

Surrounds the testis providing lubrication and mobility via mesothelial cells lining.

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Vaginal pH

Low pH environment, created through glycogen breakdown by bacteria, is hostile to many microorganisms, is hormonally dependent.

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Oestrogen & Mucous

Oestrogen causes watery mucous in the cervix which is conducive to sperm transport during ovulation and conception.

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Progesterone & Mucous

Progesterone leads to thick/sticky mucous in cervix, hindering sperm motility.

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Ovary Cortex

Outer region of the ovary containing follicles and the corpus luteum/albicans.

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Ovary Medulla

Inner region of the ovary, primarily composed of blood vessels.

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Primordial Follicle

A developing ovarian follicle present during fetal life, containing a primary oocyte.

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Primary Oocyte

Immature egg cell in an ovary.

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Ovarian Follicles

Structures in the ovary that house and nurture developing eggs (oocytes).

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Uterine Regions

The uterus has distinct regions: the fundus (top), body (main part), and cervix (lower part).

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Uterine Layers

The uterus has 3 layers: endometrium (inner), myometrium (middle muscle), and perimetrium (outer).

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Uterine Function Layer

The layer of the endometrium that is shed during menstruation and is influenced by hormones.

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Fallopian Tube Regions

The fallopian tube consists of the infundibulum, ampulla, isthmus, and uterine part.

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Fertilization Site

Fertilization typically occurs in the ampulla of the fallopian tube.

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Uterine Contractions

The myometrium layer of the uterus has rhythmic contractions, important for childbirth & other processes.

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Endometrial Regeneration

The basal layer of the endometrium remains throughout the cycle and regenerates the functional layer.

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Endometrial Phases

The endometrium goes through three phases (proliferative, secretory, menstrual) influenced by ovarian hormones.

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Seminiferous Tubules

Structures within the testis where sperm production (spermatogenesis) occurs.

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Lobules of Testis

Compartments within the testis, separated by connective tissue septa.

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Tunica Albuginea

A fibrous capsule surrounding the testis, made of thick collagen fibers.

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Rete Testis

A network of tubules connecting the seminiferous tubules to the efferent ductules.

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Efferent Ductules

Tubules that carry sperm from the rete testis to the epididymis, reabsorbing fluid.

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Epididymis

A long, coiled duct where sperm mature and are stored.

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Vas Deferens

A muscular tube carrying sperm from the epididymis to the ejaculatory duct.

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Sertoli Cells

Support cells in the seminiferous tubules that nourish developing sperm.

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Leydig Cells

Cells in the interstitial space that produce androgens (male hormones).

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Spermatogonia

Undifferentiated germ cells that give rise to primary spermatocytes.

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Primary Spermatocytes

Cells that undergo meiosis to produce sperm.

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Spermatozoa

Mature sperm cells, characterized by a head and tail.

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Smooth Muscle

Muscle in the tubules responsible for movement and peristaltic contractions.

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Pseudostratified Columnar Epithelium

Epithelial tissue in efferent ductules with different cell heights, some ciliated, some absorptive.

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Seminal Vesicles Function

The seminal vesicles (~65% seminal volume) are paired coiled ducts that produce alkaline colloid, prostaglandins, clotting proteins, and fructose, contributing to semen's composition.

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Prostate Gland Zones

The prostate gland (~30% seminal volume) has distinct zones (fibromuscular, central, peripheral), each with specialized glandular structures and functions, particularly in semen liquefaction and composition.

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Bulbourethral Glands

Bulbourethral glands produce pre-ejaculatory fluid, an alkaline lubricant, important for neutralising acidity in the urethra.

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Stellate Lumen Function

Stellate lumen, produced by folded mucosa, provides increased surface area for secretions and facilitating efficient movement of fluids.

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Vasectomy Effectiveness

A vasectomy, a surgical procedure that is designed to cut/block the vas deferens, is not immediately effective, eliminating sperm via 30 ejaculates or 2 months or other measures.

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Granulosa cells

Cuboidal cells that surround the oocyte in the follicle.

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Thecal cells

Stromal cells surrounding the follicle, squamous-like.

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Zona pellucida

Glycoprotein layer secreted by the oocyte.

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Antrum

Fluid-filled space in a secondary follicle.

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Dominant follicle

Mature follicle that develops and ovulates; ~7-25mm.

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Corpus luteum

Transient endocrine gland formed from follicle cells; produces hormones.

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Corpus albicans

Scar tissue formed from the corpus luteum if no pregnancy.

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Cumulus oophorus

Thickened layer of granulosa cells surrounding the oocyte.

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Corona radiata

Granulosa cells surrounding the oocyte immediately before ovulation.

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Atresia

Degeneration and breakdown of a follicle.

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Proliferative (oestradiol)

Nourishes early fetus through diffusion using uterine milk.

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Uterine Milk

Substance secreted by uterine glands to nourish the embryo.

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Cervix Function

Holds the baby in and regulates sperm transport via endocervical canal, lined by simple columnar epithelium.

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Ectocervix

External part of cervix, exposed to vagina, secretion depends on hormones.

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Vaginal Epithelium

Stratified squamous epithelium, high in glycogen (oestrogen), broken down by bacteria for pH regulation.

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Vaginal Rugae

Folds in the vagina allowing distention during intercourse and childbirth.

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Testis Tunica Vaginalis

Surrounds the testis providing lubrication and mobility via mesothelial cells lining.

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Vaginal pH

Low pH environment, created through glycogen breakdown by bacteria, is hostile to many microorganisms, is hormonally dependent.

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Uterine milk production by uterine glands

Cellular components situated between uterine glands start to degrade.

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Small Uterine glands

Very small uterine glands are present

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Ovarian Cortex

Outer region of the ovary containing follicles and the corpus luteum/albicans, crucial for oocyte development.

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Primordial Follicle

A fetal-life structure containing a primary oocyte, the earliest stage of follicular development.

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Primary Oocyte

Immature egg cell found within primordial and primary follicles.

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Ovarian Medulla

Inner region of the ovary primarily composed of blood vessels.

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Follicle Structure

Houses and nurtures a developing oocyte during the phases of follicle development.

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Female Reproductive Tract Transport

The fallopian tubes move the egg and sperm, nurture egg, to the uterus

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Uterine Layers

The uterus has a functional layer (shed) and a basal layer (regenerative).

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Ovarian Hormones

Oestradiol and progesterone drive changes in the uterine lining.

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Uterine Muscle Function

Myometrium: Thick muscle layer that contracts rhythmically and hypertrophies during pregnancy.

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Ampulla and Isthmus Differences

The ampulla has secretory and motility cells, while the isthmus has more secretory cells and fewer motility cells.

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Uterine Lining (Endometrium)

Endometrium is shed monthly due to hormonal changes (menstrual cycle).

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Ampulla Location

Ampulla is the site of fertilization within the fallopian tubes.

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Uterine Contractions

The myometrium's rhythmic contractions facilitate childbirth.

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Seminiferous Tubules

Tubules within the testes where sperm production occurs.

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Lobules

Compartments within the testicle, containing seminiferous tubules.

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Tunica Albuginea

Tough outer layer of the testicle, forming septa to separate lobules.

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Rete Testis

Network of channels that collect sperm from seminiferous tubules.

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Efferent Ductules

Channels that transport sperm from rete testis to epididymis; fluid reabsorption occurs.

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Epididymis

Coiled tube where sperm mature and are stored before ejaculation.

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Vas Deferens

Tube that carries sperm from epididymis to ejaculatory duct.

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Sertoli Cells

Support cells in seminiferous tubules, nurturing sperm development.

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Leydig Cells

Cells between tubules in testes, secreting testosterone.

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Germ Cells (Peripheral)

Undifferentiated and/or developing sperm cells in the seminiferous tubules.

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Spermatogonia

Stem cells that give rise to primary spermatocytes.

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Spermatozoa

Mature sperm cells, capable of fertilizing an egg.

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Smooth Muscle (epididymis/vas deferens)

Muscle layers enabling sperm transport throughout the male reproductive tract.

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Seminal Vesicles

Paired coiled ducts in males, contributing ~65% of seminal volume; have tall folds, columnar cells and produce alkaline colloid, prostaglandins, & clotting proteins, for sperm transport and viability.

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Prostate Gland

A gland in the male reproductive system; secretes ~30% of seminal fluid, has distinct zones, and contains liquefying enzymes, which help to release sperm, with fibrous capsule and many glandular structures.

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Bulbourethral Glands

Produces pre-ejaculatory fluid, an alkaline lubricant, aiding sperm transport and viability before ejaculation.

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Stellate Lumen

Stellate lumen is created by folded mucosa, which creates a unique structure in the male reproductive tract.

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Vasectomy Site

A site that can be palpated; site of vasectomy, where vas deferens is cut and sealed, is not immediately effective, requiring 30 ejaculates or 2 months for previous sperm to be cleared.

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Granulosa cells

Cells surrounding the ovum in a follicle, secreting fluid and hormones.

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Thecal cells

Cells surrounding the follicle, distinct from granulosa cells, that produce hormones.

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Zona pellucida

Glycoprotein layer secreted by the oocyte, surrounding it.

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Antrum

Fluid-filled space within a follicle, crucial for hormone release.

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Dominant follicle

Maturing follicle, the one selected for ovulation each cycle, producing significant estrogen.

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Cumulus oophorus

Thickened layer of granulosa cells surrounding the oocyte, releasing it.

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Corona radiata

Layer of granulosa cells immediately surrounding the oocyte.

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Corpus luteum

Transient endocrine organ formed from follicle cells after ovulation.

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Corpus albicans

Scar tissue, result of corpus luteum degeneration if pregnancy does not occur.

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Uterine tube

Tube carrying the egg from the ovary to the uterus, with 3 sections: infundibulum, ampulla, and isthmus.

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Breast Anatomy (Lactating)

The structure of the human breast during lactation, featuring suspensory ligaments, lactiferous ducts, lobes, lobules, and adipose tissue.

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Suspensory Ligaments

Bands of connective tissue that support and hold the breast tissue in place.

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Lactiferous Ducts

Milk-carrying tubes that drain milk from the lobules to the nipple.

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Breast Lobules

Small, grape-like clusters of milk-producing glands in the breast.

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Lactation's Importance

Lactation is crucial for newborn health, maternal health, and birth spacing.

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Lactiferous sinuses

Spaces within the breast that collect milk before release.

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Suspensory ligaments

Connective tissues supporting the breast.

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Glandular tissue location

Located closer to the nipple than previously thought, with 65% within 30mm of the nipple base.

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Arterial supply (breast)

Blood supply to the breast originates from branches of the axillary and internal thoracic arteries.

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Lymphatic drainage (breast)

Most breast lymph drains to axillary nodes (75%), with some to parasternal and abdominal nodes.

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Milk Ejection Reflex

The physiological response that causes milk release from the mammary glands.

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Alveolar Cells

Specialized cells in the breast that produce milk.

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Breast Development Stages

The different stages that breast tissue progresses through during prenatal and postnatal development.

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Milk Line Formation

Paired epidermal thickenings emerging during early human fetal development, forming a pathway for future mammary gland tissue.

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Pubertal Breast Development (External)

The observable changes in breast size and shape beginning at puberty and continuing through adolescence, characterized by distinct stages.

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Stratified Squamous Epithelium (Keratinized)

A layer of cells that protect the nipple from chafing and cracking during nursing, composing the epidermis.

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Sebaceous Gland (Nipple)

Sebaceous glands in the nipple are not connected to hair follicles and secrete sebum onto the epidermal surface.

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Lactiferous Duct

A mammary gland structure that transports milk during lactation.

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Dense Connective Tissue (Breast)

The connective tissue in the breast supporting and separating other tissues, including ducts and lobules.

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Inactive Breast (Histology)

In non-pregnant women, the breast is primarily composed of ducts and connective tissue with limited lobulo-alveolar development and fluid accumulation.

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Lactogenesis

The process of milk secretion, initiating around 40-48 hours after birth.

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Lactation

The period of milk production and secretion, maintained by infant demand and milk removal.

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Involution (breast)

The process of breast shrinkage and structural atrophy after weaning or menopause. The process gradually removes ducts and alveoli, replacing them with fat tissue.

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Hormonal control of milk secretion

Milk production is driven by prolactin from the anterior pituitary, stimulated by nipple stimulation (infant suckling).

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Milk ejection reflex

Process of releasing milk from the alveoli into ducts, driven by oxytocin from the posterior pituitary.

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Lactational Amenorrhoea

Temporary stopping of menstrual cycles during breastfeeding.

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Mean duration of Amenorrhoea

Average length of time (in relation to breastfeeding) that menstrual cycles are stopped.

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GnRH release during lactation

Erratic release of GnRH (Gonadotropin-releasing hormone) which regulates LH (Luteinizing hormone).

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Alveoli

Small sacs in the breast that produce milk.

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Lactiferous ducts

Tubules that carry milk from the alveoli to the nipple.

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Breast Anatomy (lactating)

The structure of the breast during lactation includes suspensory ligaments, lactiferous ducts, lobes, lobules, and adipose tissue.

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Suspensory Ligaments

Connective tissues that support the breast, preventing sagging.

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Lactiferous Ducts

The ducts that carry milk from the lobules to the nipple.

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Mammary Glands

Glands responsible for producing milk.

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Lactation's importance

Crucial for newborn health, maternal health, and spacing of births.

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Lactiferous sinuses

Spaces within the breast that collect milk before it's released from the nipple.

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Suspensory ligaments

Connective tissues that hold the breast up and maintain its shape.

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Glandular tissue nipple proximity

65% of breast's glandular tissue is within a 30mm radius of the nipple.

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Inactive breast composition

Inactive breasts mostly contain ducts and connective tissue, with less glandular development.

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Breast blood supply lateral branches

Breast's lateral blood supply originates from the axillary artery.

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Stratified Squamous Epithelium (Nipple)

A tough, multi-layered skin tissue that protects the nipple from chafing and cracking during nursing.

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Sebaceous Glands (Nipple)

Oil-producing glands in the nipple that are not connected to hair follicles; they secrete sebum for protection.

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Dense Connective Tissue (Breast)

A strong tissue that supports and separates the different parts of the breast, offering structural integrity.

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Lactiferous Ducts (Breast)

Milk transporting channels from the lobule to the nipple.

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Myoepithelial Cells (Breast)

Contractile cells that surround the alveoli and ducts of the mammary glands; they help expel milk.

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Milk Ejection Reflex

The reflex that causes milk release from the mammary glands.

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Alveolar Cells

Cells in the breast that produce milk.

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Breast Development

Growth and changes in breasts throughout life, from embryo to adulthood.

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Pubertal Breast Development Stages

Five developmental stages of breasts during puberty.

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Milk Line

The embryonic thickening that forms the area from which breasts develop.

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Proliferation Stage (Breast Development)

The initial growth and development of breast tissue, beginning at puberty, involving duct and lobule growth, and the forming of rudimentary alveoli.

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Lactogenesis

The process of milk secretion, triggered after birth, characterized by activated secretory alveolar cells and a significant increase in milk volume.

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Lactation

The sustained production of milk, maintained by frequent milk removal, enabling maximum milk yield for infant feeding.

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Involution (Breast)

The process of breast tissue regression after weaning, characterized by the loss of epithelial cells, and replacement of ducts/alveoli by fat tissue.

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Hormonal Control of Milk Secretion

Nipple stimulation, triggering prolactin secretion for milk synthesis, and oxytocin release for milk ejection in response to baby's need for breast feeding.

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Lactational Amenorrhea

Temporary prevention of menstrual cycles during breastfeeding, due to the suppression of ovarian activity.

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GnRH Release (Lactation)

Erratic release of GnRH (Gonadotropin-releasing hormone) during lactation, compared to a regular pattern in non-nursing women.

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Alveoli

Small sacs in the breast that produce milk.

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Myoepithelial Cells

Cells surrounding alveoli that contract to expel milk.

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Lactiferous Duct

Channels that carry milk from alveoli to the nipple.

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Gonad Descent

The movement of the gonads (testes in males, ovaries in females) from their abdominal origin to their final location.

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Ligament Remnants (Female)

The ligaments that form in the female from the gubernaculum, involved in fixing the ovary in its final location in the pelvic cavity.

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External Genitalia Formation

Development of the external genitalia, influenced by the presence or absence of androgens and estrogens, creating differences between sexes in the early development.

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Cloacal Urogenital Sinus

The early embryonic structure that forms the urogenital tract and is critical in differentiation.

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Gender differences (external)

The physical differences in external genitalia appearance between male and female embryos, resulting from factors such as androgens or estrogens.

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Scrotal Heat Exchange

The mechanisms (Dartos muscle and counter-current exchange) that control the temperature of the scrotum to maintain optimal sperm viability.

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Persistent Müllerian Duct Syndrome

A genetic condition in males where the Müllerian ducts, which typically regress, persist, resulting in the presence of female internal reproductive structures.

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Paramesonephric duct disintegration (male)

The process in which the paramesonephric duct, which develops into the female reproductive tract, regresses in males during development.

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Reproductive Tract Development

The process by which the organs of the reproductive system form during prenatal development.

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Gonad Development

The formation of the testes or ovaries from primordial germ cells and supporting cells.

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Primordial Germ Cells

Early embryonic cells destined to develop into gametes.

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Genital Tract Development

The development of the male and female reproductive ducts and external genitalia during fetal development.

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Sexual Dimorphism

The process by which male versus female reproductive systems develop differences, including external and internal structures.

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Gonad Formation

Early development of the sex organs (ovaries or testes).

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SRY gene

A gene that triggers the development of the testis.

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Sertoli cells

Support cells in the testis that form sperm-producing tubules.

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Leydig cells

Testis cells secreting testosterone.

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Anti-Mullerian Hormone (AMH)

Hormone that suppresses paramesonephric duct development preventing female tract formation.

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Oogonia

Immature egg cells (in females).

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Primordial follicle

A follicle surrounding an oocyte, initially forms in females.

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Mesonephric duct

A duct that may form part of the male or degenerate in the female reproductive system.

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Paramesonephric duct

A duct that forms most of the female reproductive tract or degenerates in males.

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Gubernaculum

Fibrous cord that guides gonad descent.

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Gonad Descent

The process by which the testes descend from the abdominal cavity into the scrotum during fetal development.

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Ligament Remnants (Female)

Structures like the round ligament (ligamentum teres) retain the connection between the ovary and external genitalia.

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External Genitalia Formation

Development of the external reproductive organs starts as undifferentiated structures in the embryo, which later become male or female organs.

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Female External Genitalia

The development of the female external genitalia does not involve the folding of the urethral folds to form a penile urethra, resulting in a short clitoris and separate vaginal and urethral openings.

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Cloacal Septum

A wall that develops between 12 weeks during fetal development and separates the urogenital and anal openings.

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Scrotal Heat Exchange

The scrotum regulates temperature to maintain ideal sperm viability with the help of contractile muscles and countercurrent heat exchange.

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Persistent Müllerian Duct Syndrome

A genetic condition in males where the paramesonephric (Müllerian) duct system does not degenerate like it normally does during fetal development, resulting in some female reproductive structures in males.

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Mesonephric Duct

The duct that gives rise to parts of the male reproductive tract, including portions of the epididymis, vas deferens, and seminal vesicle.

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Primordial germ cells (PGC)

Specialized cells that develop into gametes (sperm or egg cells).

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Sexually dimorphic reproductive tracts

Reproductive tracts that differ significantly between males and females.

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Urogenital development

The formation of both the urinary and reproductive systems in embryos.

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Gonads

Organs (testes in males and ovaries in females) that produce gametes and hormones.

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Development of genital tracts

Different development paths for male and female genital structures starting from similar embryonic tissues.

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Gonadal Differentiation

The process where indifferent gonads develop into either testes or ovaries, determined by genetic and physiological factors.

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SRY Gene

A gene on the Y chromosome that initiates the development of testes.

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Sertoli Cells

Support cells in the testis that produce Anti-Müllerian Hormone (AMH) and stimulate spermatogenesis.

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Leydig Cells

Cells in the testis that produce testosterone, crucial in male development and secondary sexual characteristics.

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Anti-Müllerian Hormone (AMH)

A hormone produced by Sertoli cells that prevents the development of female reproductive ducts.

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Primordial Follicle

A developing follicle surrounding an oocyte (early egg) created during female gonadal development.

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Oogonia

The precursor cells to oocytes (immature egg cells) in female gonads.

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Mesonephric Duct

A duct in both sexes during fetal development, it's also part of the urinary system and will degenerate in females but important in male urinary and reproductive systems

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Gubernaculum

A fibrous cord that guides the gonad (testis or ovary) during development.

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Para-mesonephric Duct

Also known as Mullerian duct, a structure of the female reproductive system.

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Scarpa's fascia

The superficial abdominal fascia, continuous with Colles' fascia.

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Colles' fascia

Superficial perineal fascia, also known as the dartos fascia. Continuous with Scarpa's fascia.

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Buck's fascia

The deep penile fascia, covering male erectile tissues.

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Perineal body

A central structure in the perineum, where the superficial and deep perineal compartments meet.

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Perineal membrane

A fibrous sheet that forms the inferior boundary of the deep perineal pouch.

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Dorsal nerve of penis/clitoris

Nerve supplying skin and erectile tissues of the penis/clitoris.

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Perineal muscles

Layers of muscles within the perineum.

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Evolution of perineum

The perineum is a continuum of the body wall muscle layers; 4 in tetrapods, but we discuss 3.

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Perineum Definition

The region between the pubic symphysis and the coccyx, including the anal and urogenital triangles.

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Perineal Triangles

The perineum is divided into the anal triangle (for the anus) and the urogenital triangle (for the reproductive/urinary structures).

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Anococcygeal Raphe

A midline seam of connective tissue that separates the anal and urogenital triangles.

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Perineal Body

A central connective tissue mass in the perineum, crucial for support and attachment of surrounding structures.

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Pudendal Nerve Function

Major nerve supplying the perineum's skin, muscles, and sensation; branches supply external anal sphincters, perineal skin.

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Deep Transverse Perineal Muscle

A muscle located in the perineum that stabilizes the perineal body by connecting to the ischial ramus and perineal body.

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External Urethral Sphincter

A muscle that compresses the urethra. Relaxes during urination.

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Pudendal Nerve Pathway

Exiting the greater sciatic foramen and entering the lesser sciatic foramen the branches supply the perineum's various structures.

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Perineal Membrane

Fibrous sheet supporting the superficial perineal pouch, allowing for tension to structures beneath

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Perineal body

A crucial connective tissue (not a muscle) in the perineum. Many pelvic floor muscles attach to it.

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Compressor urethrae

An accessory muscle that helps close the urethra, mostly in females.

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Inferior Rectal Nerve

Nerve branch from pudendal nerve, that innervates the external anal sphincter muscles and surrounding skin, part of the anal triangle.

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Deep external anal sphincter

Muscle surrounding the anal canal that closes it.

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Perineal Muscle Layers

The perineum is divided into layers, each containing different muscles and structures.

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Superficial External Anal Sphincter

A voluntary muscle in the anal triangle, part of the superficial perineal layer.

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Ischiorectal/Ischioanal Fossa

A space in the perineum, lateral to the rectum, containing fat and blood vessels.

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Male Erectile Tissues

Corpora cavernosa and corpus spongiosum, within the superficial perineal layer, vital for erection.

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Urogenital Diaphragm

A sheet of muscle acting like a barrier between the pelvic cavity and perineum, supporting and closing off the urinary and genital openings.

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Female Homologous Structures

Female reproductive structures analogous to male structures, like the bulb of the vestibule, clitoris, and greater vestibular gland.

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External Urethral Sphincter (Male and Female)

A muscle in the urogenital diaphragm that controls urination, found in both sexes.

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Deep Perineal Pouch

The region in the perineum containing the urogenital diaphragm and supporting pelvic structures

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Deep External Anal Sphincter

A muscle that surrounds the anal canal, contributing to control of bowel movements.

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Male Deep Pouch Contents

Contains the bulbourethral gland in the male pelvic floor.

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Pelvic Floor Muscles

A layer of muscles supporting pelvic organs, crucial for bowel and bladder control.

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Urogenital Diaphragm

Muscles and connective tissue forming the floor of the urogenital triangle.

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Superficial Pouch Contents

Contains erectile tissue and muscles of layer 2 in both males and females.

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Deep Pouch Layers

The deep pouch is composed of a superior fascia layer, muscles, and an inferior perineal membrane.

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Bulbospongiosus Muscle

A muscle in the superficial perineal pouch that plays a role in ejaculation and urination.

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Ischiocavernosus Muscle

A muscle that helps maintain blood flow to erectile tissue in the penis/clitoris.

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Sphincter urethrovaginalis location

Located in the perineal body, anterior to the vaginal opening and the urethra.

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Levator Ani muscle layers

Deep layer of muscles in the pelvic floor, supporting pelvic viscera and maintaining anal and vaginal sphincters.

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Puborectalis origin

Originates from the tendinous arch across the obturator fascia, from posterior pubic bone to ischial spines.

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Iliococcygeus function

A muscle within the pelvic floor which forms part of the pelvic floor and helps support viscera.

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Ischiococcygeus function

Flexes the coccyx after defecation, forming part of Pelvic floor supporting visceral organs.

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Scarpa's fascia

The superficial abdominal fascia, continuous with Colles' fascia.

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Colles' fascia

Superficial perineal fascia, also known as dartos fascia.

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Buck's fascia

Deep penile fascia that surrounds the male erectile tissues, extending with them.

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Perineal body

Connective tissue mass situated in the posterior perineum.

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Perineal membrane

Fibrous sheet forming the floor of the superficial perineal pouch.

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Perineal compartments

Different layers of tissue within the perineum organized distinctly.

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Perineum evolution

The perineum is an evolution of the body wall, with mammalian variations.

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Mammalian perineum layers

Perineum's distinct layers (subcutaneous, external, internal, transverse).

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Perineum Definition

The region between the anal and urogenital openings, comprising the pelvic floor and structures beneath.

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Perineal Triangles

The perineum is divided into two triangles: the anal triangle and the urogenital triangle.

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Anococcygeal Raphe

A fibrous seam that runs from the coccyx to the anus.

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Perineal Body

A fibrous mass central to the perineum, a site of attachment for muscles.

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Pudendal Nerve (S2-S4)

A major nerve supplying the perineum, branches to the anal and urogenital regions.

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Pudendal Nerve Branches

The pudendal nerve branches to control the skin and muscles of the perineum and the rectal area.

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Perineal Membrane

A sheet of connective tissue forming the floor of the urogenital triangle.

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Erectile Tissues (Perineum)

Specialized tissues, found in urogenital triangle, capable of engorgement (penile vs. labial)

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Deep External Anal Sphincter

A muscle that constricts the anal canal, aiding in continence.

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Deep Pelvic Pouch Contents (Male)

The deep pouch within a male's pelvis contains muscles of the uro-genital diaphragm and bulbourethral glands.

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Pelvic Floor Layers

Layers of muscles and fascia forming the pelvic floor, supporting pelvic organs.

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Levator Ani Muscles

Main group of pelvic floor muscles that have 3 parts: puborectalis, pubococcygeus, and iliococcygeus; responsible for stabilizing the pelvic floor.

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Urogenital Diaphragm

A tissue structure (fascia) in the urogenital triangle.

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Superficial Pelvic Pouch

Space beneath the perineal membrane and skin structures, housing male erectile tissue and muscles.

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Superficial Pouch Contents (Male)

Male superficial pouch contains erectile tissues and superficial perineal muscles (bulbospongiosus, ischiocavernosus, superficial transverse perineal).

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Bulbospongiosus Muscle Function

Muscle responsible for expelling urine and ejaculating semen.

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Superficial Perineal Layer

The outermost layer of the perineum, containing the subcutaneous body wall and superficial external anal sphincter.

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Ischiorectal/Ischioanal Fossa

The space located laterally within the superficial perineal layer, situated between the obturator internus, ischiopubic rami, rectum, & anus, and urogenital tracts.

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Deep Perineal Layer

The layer underneath the superficial perineal layer, containing the urogenital diaphragm muscles and supporting pelvic viscera.

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Urogenital Diaphragm

A muscular structure supporting pelvic viscera and acting as a sphincter in the deep perineal layer.

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Erectile Tissue

Specialized tissues found in the second layer of the perineum, specifically in the male and female superficial pouches, and responsible for sexual response.

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External Urethral Sphincter

A muscle of the urogenital diaphragm, which controls the flow of urine.

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Perineal Membrane

A fibrous sheet of tissue that forms the inferior border of the deep pouch, anchors erectile tissues, and supports some muscles.

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Superficial Pouch

The superficial compartment of the perineum which contains erectile tissue, muscles, and additional structures like the testes or greater vestibular gland.

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Deep Transverse Perineal Muscle

A muscle in the perineum that stabilizes the perineal body by attaching to the ischial ramus and perineal body.

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Perineal Body

A central connective tissue mass in the perineum, a crucial anatomical landmark.

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External Urethral Sphincter

Sphincter muscle compressing the urethra, relaxing for urination.

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Compressor Urethrae

An accessory muscle for urethral compression, located anteriorly to urethra in females.

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Deep External Anal Sphincter

Muscle encircling the anal canal, closing the canal.

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Sphincter urethrovaginalis

Muscle in the perineal body, anterior to the vaginal opening, that surrounds the urethra. It helps control flow of urine and fluids.

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Levator Ani muscles

Group of muscles forming the pelvic floor; important for supporting pelvic organs and maintaining continence.

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Puborectalis

Part of Levator Ani, supports the rectoanal junction helping control bowel and urine.

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Pelvic Floor Layer 4

Deepest layer of muscles in the pelvic floor, composed of transverse body wall and muscles.

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Iliococcygeus/Ischiococcygeus

Muscles of the pelvic floor that support and flex/support viscera, the coccyx after defecation.

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Pelvic Girdle

The bony structure formed by the sacrum and two coxal bones, providing support for the pelvic viscera.

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Os Coxa

Each hip bone, formed by the fusion of three bones: ilium, ischium, and pubis.

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Pelvic Viscera

Organs located within the pelvis, including portions of the reproductive and digestive systems, as well as the urinary bladder.

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Pelvic Joints

The joints connecting the bones of the pelvis, including the sacroiliac joints and the pubic symphysis.

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Female vs. Male Pelvis

Differences in pelvic shape and structure between males and females, reflecting differing evolutionary pressures and purposes.

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Pelvic Walls

Structures that form the sides and floor of the pelvis, composed mostly of muscles and ligaments.

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Pelvic Ligaments

Bands of connective tissue that support pelvic structures and joints.

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Pelvic Inlet

The opening into the pelvis, differing in shape between males and females, impacting childbirth.

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Obturator Foramen

An opening in the hip bone that allows passage of blood vessels, nerves, and muscles.

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Greater Sciatic Foramen

An opening created between the sacrospinous and sacrotuberous ligaments in the pelvis, allowing structures to pass.

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Lesser Sciatic Foramen

A smaller opening in the pelvis, situated inferior to the greater sciatic foramen, for passage of structures.

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Sacrotuberous Ligament

A fibrous ligament connecting the sacrum to the ischial tuberosity, contributing to pelvic stability.

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Sciatic Nerve

A major nerve in the pelvis that passes through the greater sciatic foramen; providing sensation and motor function.

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Force Transduction (Lower Limb)

The process of transmitting weighted loads efficiently between the vertebrae, hip bone (os coxa), and limbs, including limb-to-limb transmission; critical for movement and stability.

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Pelvic Brim

The superior (upper) opening of the bony pelvis, the boundary between the false and true pelvis.

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True Pelvis

The part of the pelvis below the pelvic brim, enclosed by bone; contains pelvic organs.

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Pelvic Outlet

The inferior (lower) opening of the pelvis, bound by bone and ligaments; defines the area through which structures exit.

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False Pelvis

The superior part of the pelvis, above the pelvic brim, primarily made of the ilium.

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Ground Reaction Force

The force exerted by the ground in response to the forces applied by the body.

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Obturator Foramen

A large opening in the hip bone, located on the internal side of the pelvis, allowing passage of blood vessels and nerves.

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Pelvic Outlet Boundaries

The inferior opening of the pelvic cavity, bordered by the ischial tuberosities, ischiopubic rami, sacrotuberous ligaments, and muscles/fascia.

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Lesser sciatic foramen

A passageway in the pelvis, allowing structures to enter and exit the pelvic cavity.

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Pelvic diaphragm muscles

Muscles forming the floor of the pelvic cavity; help close the outlet.

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Pubic symphysis

Cartilaginous joint connecting the two pubic bones.

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Obturator internus tendon

Tendon that passes through the lesser sciatic foramen to rotate the leg.

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Mechanical pubic link strength

Posterior link between pubic bones is stronger than the anterior link.

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Lumbosacral Joint Stability

The stability of the L5-S1 joint, maintained by the lumbosacral intervertebral disc and articular processes, and the iliolumbar ligament.

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Sacral Rotation

The tendency of the sacrum to rotate forward relative to the ilium.

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Anterior Pelvic Rotation

The rotation of the pelvis forward, resisted by ligaments and the gravity center.

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Iliolumbar Ligament Function

The iliolumbar ligament resists the tendency of the sacrum to rotate forward relative to the ilium, and thus avoids anterior slipping.

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Vertical Centre of Gravity (CoG)

The body's center of gravity, located roughly at the S2 segment.

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Pelvic Ligament Resistance

Ligaments, including the dorsal interosseous, sacrotuberous, and sacrospinous ligaments, resist anterior pelvic rotation.

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Lumbosacral IVD

The intervertebral disc between the L5 and S1 segments; contributes to stability of lumbosacral joint.

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Sagittal Stability at the Lumbosacral Junction

The stability, in the sagittal plane, of the spinal column's transition at the Lumbosacral Joint (L5-S1).

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Female Pelvic Evolution

The female pelvis has evolved for functions beyond just childbirth, with pre-birth work capacity being a bigger evolutionary pressure than birth itself.

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Bipedal Efficiency & Visceral Prolapse

Ischial spines improve bipedal walking efficiency, but also reduce the risk of visceral organs (e.g., intestines) protruding during pregnancy.

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Human Pelvis Adaptation

The human pelvis is highly adapted for bipedalism, with features like a broader sacrum, wider acetabular space, and flared ilia.

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Pelvis & Trunk Size

Pelvic adaptations allow for a large trunk size needed for efficient bipedalism. A need to counterbalance the long, heavy lower limbs.

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Pelvis & Energy Requirement

A stable trunk during walking reduces energy required for maintaining an upright posture during bipedalism.

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Pelvic Rotational & Frontal Movement

The human pelvis's structure allows for efficient rotational and frontal body movements, supported by the abdominal oblique muscles for elastic energy storage during walking/running.

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Reduced Bending Moment

A shortened and deepened ilial neck in humans positions the center of gravity closer to the hip joint, reducing the bending moment in the ilia.

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Acetabular Socket Angling

The human acetabular socket is angled more inferiorly and less laterally compared to other primates.

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Obturator Foramen

An opening in the hip bone, through which muscles, nerves, and blood vessels pass.

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Greater Sciatic Foramen

Opening in the pelvis created by sacrospinous and sacrotuberous ligaments; allows passage of important nerves and blood vessels.

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Lesser Sciatic Foramen

Opening in the pelvis smaller than the greater sciatic foramen, also bounded by the sacrospinous and sacrotuberous ligaments, allowing passage of some nerves and blood vessels.

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Sacrotuberous Ligament

A fibrous band connecting the sacrum to the ischial tuberosity, forming part of the pelvic outlet.

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Sacrospinous Ligament

A fibrous band connecting the sacrum to the ischial spine, forming part of the pelvic outlet and contributing to the greater and lesser sciatic foramina.

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Pelvic Girdle

The structure formed by fusion of the sacrum with two os coxae, which are each formed from the fusion of the ilium, pubis, and ischium.

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Pelvic Function (2 main)

The pelvis serves as a basin for pelvic organs and plays a vital role in bipedal locomotion and childbirth.

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Os Coxa

The hip bone; formed by the fusion of three separate bones (ilium, pubis, ischium).

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Pelvic Sexual Dimorphism

Structural differences in the pelvis between males and females, shaped by evolutionary pressures.

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Pelvic Joints

Joints between the pelvic bones. Include sacroiliac, pubic symphysis, and the hip joints.

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Pelvic Walls

Structures that form the lateral and posterior boundaries of the pelvis.

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Pelvic Parts

The pelvic region comprises the sacrum, coccyx and two os coxae (hip bones).

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Pelvic Ligaments

Connective Tissues that hold the pelvic bones together, maintaining structural integrity.

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Force Transduction (Lower Limb)

The process of transferring weighted loads between the vertebrae, pelvis, and lower limbs, ensuring efficient transmission of forces.

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Pelvic Brim

The opening into the pelvis, shaped differently in men and women.

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Pelvic Outlet

The inferior opening of the pelvic cavity, defined by key bony structures and ligaments.

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True Pelvis

Below the pelvic brim, containing pelvic organs.

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False Pelvis

Above the pelvic brim, mostly made up of the ilium.

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Obturator Foramen

A large opening in the pelvis filled by a membrane.

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Ground Reaction Force

Force exerted by the ground in response to forces from one's body.

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Pelvic Inlet

The opening into the true pelvis

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Lesser sciatic foramen

An opening in the pelvis through which structures like the obturator internus tendon and pudendal nerve pass.

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Pelvic diaphragm muscles

Muscles forming the floor of the pelvic cavity, closing it off from the visceral pelvis.

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Pubic symphysis

The joint connecting the two pubic bones; a weaker anterior link between limbs.

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Anterior mechanical link

The pubic symphysis linking the limbs, but weaker than the posterior link.

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Bone-cartilage-bone structure

The pubic symphysis has a structure of bone-hyaline cartilage-fibres-hyaline cartilage-bone.

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Sacroiliac joint (SI) stability

The SI joint, a crucial joint, is remarkably stable due to its strong ligaments and the 'keystone' principle, which focuses a ground force through our bodies. This limits excessive slippage or movement, resisting forces.

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SI joint slippage

The SI joint can move (slip) in the frontal plane, but this movement is limited and controlled by strong dorsal ligaments to protect from injury or excessive movement.

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SI Joint stability mechanism

The directional stability of the SI joint is maintained by strong ligaments like the iliolumbar and dorsal interosseous sacroiliac ligaments; increased slippage means greater tension.

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Force sharing in the SI joint

Forces exerted on our body through our legs are transferred to the SI joint. Important forces on the SI joint are transferred through the body to the limbs; for example, damage occurs from impact injuries, when the body's impact forces are transferred into the joints.

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Postpartum Joint Cavity

A fluid-filled capsule forms in the joint of some women after childbirth. This is a tissue-specific response to events after birth.

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Human Pelvis Adaptation

The human pelvis is highly evolved for efficient bipedalism, featuring broader sacrum, wider acetabular space, flared ilia, and specific adaptations in the ilial neck, facilitating rotational and frontal movements.

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Bipedal Efficiency & Visceral Prolapse

Ischial spines enhance bipedal efficiency, while mitigating visceral prolapse risk during pregnancy in humans.

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Pelvic Adaptation for Trunk Size

Pelvic adaptations allow for an optimal trunk size that facilitates efficient bipedalism and balances trunk inertia with lower limb inertia.

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Lower Limb Inertia in Bipedalism

The long and heavy human lower limbs necessitate adaptations in the trunk to create a comparable counterweight, optimizing balance and energy use during bipedal movement.

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Acetabular Angulation & Pelvic Width

The acetabular socket's downward angle and consistent pelvic width align the feet within the pelvic dimensions, crucial for maintaining stability during bipedal locomotion.

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Energy Efficiency in Walking

Reduced trunk sway during walking in humans conserves energy, an adaptation that is critical for bipedal locomotion, reducing energy requirements for maintaining posture.

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Bipedalism & Pregnancy Pressure

The pressure toward bipedal efficiency in human evolution during pregnancy is greater than pressures toward childbirth itself; pre-birth work capacity is a stronger selection force.

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Ilial Neck Deepening

A shortened and deepened ilial neck in humans positions the center of gravity closer to the hip joint, facilitating balance and support of our larger, bipedal body structure reducing bending force when bipedal.

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Pituitary Gland Location

Located in the sella turcica (or pituitary fossa) of the sphenoid bone, posterior to the sphenoid air sinus.

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Anterior Pituitary (Adenohypophysis)

Part of the pituitary gland composed of glandular epithelial tissue.

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Pars Distalis

Largest portion of the anterior pituitary, containing hormone-secreting cells.

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Acidophils (Pituitary)

Anterior pituitary cells secreting growth hormone (GH) and prolactin.

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Basophils (Pituitary)

Anterior pituitary cells secreting ACTH, TSH, FSH, and LH.

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Posterior Pituitary (Neurohypophysis)

Part of the pituitary gland storing and releasing hormones produced by the hypothalamus.

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Hypothalamic-Hypophyseal Tract

Axons connecting hypothalamic nuclei to the posterior pituitary.

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Herring Bodies

Swollen terminals of hypothalamic nerve fibers in the posterior pituitary, storing hormones.

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Pituicytes

Glial cells in the posterior pituitary that regulate hormone release.

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Infundibulum

Stalk connecting the pituitary gland to the hypothalamus.

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Portal Venous System (Pituitary)

Network of capillaries connecting the hypothalamus and anterior pituitary, allowing hypothalamic hormones to act on anterior pituitary.

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Pars Tuberalis

Part of the anterior pituitary wrapped around the infundibulum.

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ADH (Antidiuretic Hormone)

Hormone produced in the hypothalamus, stored and released by the posterior pituitary, that helps regulate water balance.

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Oxytocin

Hormone produced in the hypothalamus, stored and released by the posterior pituitary, associated with childbirth and bonding.

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Pineal Gland

Endocrine gland situated behind the thalamus, in the brain.

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Blood vessel

A tube carrying blood throughout the body.

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Basophil

A type of white blood cell involved in immune responses.

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Acidophil

A type of cell in the anterior pituitary.

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Chromophobe

Type of cell in the anterior pituitary that doesn't stain.

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Anterior pituitary

Part of the pituitary gland that produces and releases hormones.

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Hormone stored in nerve endings

Hormones, like oxytocin and antidiuretic hormone, stored in the posterior pituitary.

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Glial cell (pituicytes)

Support cells in the posterior pituitary.

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Pineal gland

An endocrine gland in the brain that secretes melatonin.

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Pinealocytes

Cells in the pineal gland that secrete melatonin.

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Melatonin

Hormone that regulates sleep/wake cycles.

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Thyroid Location

Located in the anterior neck, deep to cervical strap muscles, inferior to thyroid and cricoid cartilages.

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Thyroid Lobes

Two lobes connected by an isthmus, a narrow band of tissue.

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Pyramidal Lobe

A remnant of thyroid tissue migration; often superior and midline of thyroid.

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Superior Thyroid Arteries

Branches from external carotid artery, supplying blood to the superior thyroid.

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Inferior Thyroid Arteries

From the thyrocervical trunk (branch of subclavian artery) serving inferior aspects.

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Thyroid Venous Drainage

Superior and middle veins drain to IJV; inferior drains to brachiocephalic, IJV, or SVC.

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Thyroid Innervation

Sympathetic nerves from cervical ganglia provide innervation.

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Thyrocervical Trunk

Branch of the subclavian artery supplying blood to cervical and upper thoracic structures, including the inferior thyroid arteries.

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Mineralocorticoids (e.g., aldosterone)

Hormones secreted by the adrenal cortex that regulate water retention, primarily aldosterone.

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Zona Fasciculata

Layer of the adrenal cortex, responsible for secreting glucocorticoids, mainly cortisol.

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Glucocorticoids (e.g., cortisol)

Hormones that regulate blood sugar and stress response, mainly cortisol from Zona Fasciculata.

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Pancreatic Islets (of Langerhans)

Groups of cells within the pancreas that produce and secrete hormones, such as insulin and glucagon.

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Alpha cells (pancreas)

Pancreatic islet cells secreting glucagon, which increases blood sugar.

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PP-cells function

Pancreatic polypeptide cells (epsilon cells) regulate gastric chief cells, inhibiting bile, pancreatic enzymes, bicarbonate, and intestinal motility.

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Pancreas Beta Cells

The pancreatic cells that produce insulin.

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Pancreas Alpha Cells

The pancreatic cells that produce glucagon.

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Clinical Relevance (Pregnancy)

Pregnancy can impact various physiological processes, including those relating to the endocrine system.

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Hyperthyroidism and Goiter

A condition involving an overactive thyroid gland, often associated with iodine deficiency.

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Adrenal Gland Location

Located on top of the kidney, primarily in the retroperitoneal space.

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Adrenal Blood Supply

Supplied by paired adrenal arteries from the abdominal aorta, with additional branches potentially from inferior phrenic and renal arteries. Arteries reach the cortex first.

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Adrenal Vein Drainage

Drains in a cortex-to-medulla direction (unlike counter-current), with the central adrenomedullary vein ultimately reaching the renal vein (caval system).

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Adrenal Medulla Histology

Contains chromaffin cells, which synthesize and secrete adrenaline/noradrenaline (catecholamines). Blood vessels are centrally located with fenestrated capillaries.

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Adrenal Medulla Innervation

Innervated by sympathetic nerves from the aorticorenal ganglion (T10-11); parasympathetics innervating local blood vessels.

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Zona Glomerulosa

Small curved cell columns with dark nuclei; part of the adrenal cortex. Spongy appearance.

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Chromaffin Cells

Cells in the adrenal medulla that produce and release adrenaline and noradrenaline (catecholamines).

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Adrenal Hormones

Epinephrine and Norepinephrine, important for stress responses, and have systemic effects, more lasting than the autonomic nerves function.

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Pituitary Gland Location

Located in the sella turcica (pituitary fossa) of the sphenoid bone, posterior to the sphenoid air sinus, and surrounded by the cavernous dural sinus.

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Posterior Pituitary Connection

Connected to the hypothalamus via the infundibulum, containing the hypothalamic-hypophyseal tract.

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Anterior Pituitary Histology

Composed of epithelial glandular tissue, with different cell types (acidophils, basophils, chromophobes) each secreting specific hormones.

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Pars Distalis Cells

The largest part of the anterior pituitary containing acidophils (GH, prolactin) & basophils (ACTH, FSH, LH, TSH) that secret specific hormones.

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Pars Tuberalis

Part of anterior pituitary wrapped around the infundibulum. Provides more vasculature for regulation.

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Pars Intermedia Function

Mostly basophilic cells mainly secreting melanocyte-stimulating hormone (MSH).

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Posterior Pituitary Function

Stores and releases hormones ADH and oxytocin, produced in the hypothalamus.

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Hypothalamic-Hypophyseal Tract

Nerve fibers carrying hormones from the hypothalamus to the posterior pituitary.

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Herring Bodies

Swollen terminals of nerve cells in the posterior pituitary that store hormones ADH or oxytocin.

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Pituicytes

Specialized glial cells regulating hormone release from the Herring bodies.

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Portal Venous System

Unique system connecting hypothalamic blood vessels to the anterior pituitary.

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Anterior Pituitary Hormones

Secretes multiple hormones (ACTH, FSH, LH, TSH, GH, PRL).

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Infundibulum

The stalk that connects the hypothalamus to the pituitary gland.

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Blood vessel

A tube that carries blood throughout the body.

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Basophil

A type of white blood cell involved in allergic reactions.

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Acidophil

A type of anterior pituitary cell that secretes hormones.

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Chromophobe

A type of anterior pituitary cell with no visible granules.

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Anterior pituitary

Part of the pituitary gland that produces and releases hormones.

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Hormone stored in nerve endings (Herring bodies)

Hormones stored in the posterior pituitary for release.

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Glial cells

Cells supporting and nourishing neurons in the brain

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Pineal Gland

A gland in the brain that produces melatonin.

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Pinealocytes

Cells in the pineal gland responsible for melatonin secretion.

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Melatonin

A hormone that regulates sleep-wake cycles.

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Thyroid Location

Deep to cervical strap muscles, inferior to thyroid & cricoid cartilages, with two lobes connected by an isthmus; may have a pyramidal lobe.

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Thyrocervical Trunk

Branch of subclavian artery supplying inferior thyroid arteries.

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Superior Thyroid Arteries

Branches from external carotid artery, supplying the superior part of the thyroid.

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Thyroid Venous Drainage

Superior and middle thyroid veins drain into internal jugular vein; inferior thyroid veins may drain into brachiocephalic, IJV, or SVC.

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Thyroid Innervation

Sympathetic nerves from cervical ganglia (superior/middle/inferior) innervate the thyroid.

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Isthmus

Narrowing connecting two thyroid lobes, like a bridge between two seas.

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Pyramidal Lobe

Remnant of thyroid migration, usually pointed towards the midline.

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Superior Thyroid Artery Branch

Branch of the external carotid artery.

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Mineralocorticoids

Steroid hormones, like aldosterone, that regulate salt and water balance in the body.

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Zona Fasciculata

The middle layer of the adrenal cortex, which secretes cortisol, a key glucocorticoid.

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Glucocorticoids

Steroid hormones, primarily cortisol, that regulate blood glucose levels and respond to stress.

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Pancreatic islets (of Langerhans)

Clusters of endocrine cells within the pancreas, producing hormones like insulin and glucagon.

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Glucagon

A hormone secreted by alpha cells in the pancreatic islets, that raises blood glucose levels.

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Vagus Nerve Branches

The vagus nerve (CN X) has laryngeal and recurrent laryngeal branches that provide both sensory and motor function to the larynx and other structures.

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Thyroid Follicles

Thyroid follicles are sacs filled with colloid, which stores thyroglobulin, containing thyroid hormones.

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Thyroglobulin

A large protein produced by follicular cells that binds to and stores thyroid hormones (T3 and T4).

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T3 (Triiodothyronine)

A more potent thyroid hormone that regulates metabolic rate in many tissues.

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TSH (Thyroid Stimulating Hormone)

A hormone from the anterior pituitary that stimulates follicular cells to extract thyroglobulin and generate T3 and T4.

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Parafollicular Cells

Cells found between thyroid follicles that produce calcitonin, which helps with calcium homeostasis.

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Calcitonin

A hormone secreted by parafollicular cells that decreases blood calcium levels by inhibiting osteoclasts.

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Parathyroid Gland Location

The parathyroid gland is located on the posterior surface of the thyroid gland.

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Chief Cells (Parathyroid)

The most common type of parathyroid cell that secretes parathyroid hormone (PTH) to increase blood calcium.

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Parathyroid Hormone (PTH)

A hormone that increases blood calcium levels by stimulating osteoclast activity and increasing calcium absorption from the gut.

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Adrenal Gland Location

Located on top of the kidneys, in a retroperitoneal position.

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Adrenal Gland Blood Supply

Supplied by paired adrenal arteries from abdominal aorta, with potential branches from other arteries, entering through the external capsule, targeting the cortex first.

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Adrenal Gland Drainage

Drains in a cortex to medulla direction.Central adrenomedullary vein to renal veins (which are in the caval system).The right adrenal gland can drain directly into IVC

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Adrenal Medulla Histology

Contains chromaffin cells synthesizing and secreting adrenaline and noradrenaline (catecholamines), with light pale nuclei and pale cytoplasm.

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Adrenal Medulla Innervation

Innervated by sympathetics from the aorticorenal ganglion (T10-T11), and some parasympathetics (to blood vessels) from the vagus nerve.

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Chromaffin Cells

Cells in the adrenal medulla that produce and release adrenaline and noradrenaline.

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Zona Glomerulosa

Outer layer of the adrenal cortex characterized by small, curved cell columns and relatively dark round nuclei.

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Adrenal Medulla Venue

The central section of the adrenal medulla, home to chromaffin cell clusters and many large blood vessels

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Pineal Gland Calcification

A common process where the pineal gland develops calcium deposits, often correlating with age and more frequent in females.

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Precocious Puberty (Pineal Tumor)

Early onset of puberty, sometimes linked to a tumour in the pineal gland.

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Pharyngeal Arch Cleft

External grooves that develop from surface ectoderm during embryo development, contributing to structures like the external ear.

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Pharyngeal Arch Pouches

Internal pouches that develop from the embryo's interior and contribute to various structures (tonsils, parathyroid, thymus, C-cells of thyroid).

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Thyroid Development Origin

The thyroid gland originates from the foramen caecum of the tongue, migrating to the neck.

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Thyroid Follicle Development

Thyroid follicles become functional around 10-11 weeks of gestation, critical for lung maturation.

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Thyroid Hormone & Lung Development

Thyroid hormone accelerates lung development, increasing alveolar septation and compliance.

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Maternal Iodine Deficiency

Low maternal iodine intake affects fetal thyroid development, potentially causing neural hormone abnormalities.

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Fetal Thyroid Hormone & Brown Fat

High thyroid hormone (TH) in late fetal development stimulates brown fat development, crucial for non-shivering thermogenesis.

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Axolotl & Iodine

Axolotls, having external gills and skin breathing, demonstrate adaptation in the face of fluctuating water availability and iodine intake.

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Thyroid Gland Location

The thyroid gland is situated in the neck and upper thorax.

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Thyroid Cancer

Cancer can develop in the cells of the thyroid gland or in cells of the ducts.

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Ancient Lineage of Thyroid

The role of TH in lung development predates modern understandings; it is an ancient process.

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Surface ectoderm

Outer layer of cells in the early embryo that develops into skin and related structures.

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Endoderm

Inner layer of cells in the early embryo that forms the lining of organs like the gut and lungs.

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1st order nerve

Nerve fibers in the early stages of development. Often the initial branch coming from a main nerve

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2nd order nerve

Nerve fibers that branch out further from a major nerve trunk in the development.

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Palatine

Related to the hard or soft palate, depending on context

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Pelvic Inlet Angle

The angle formed by the opening into the pelvis, differing between males and females.

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Rectal Curve

The curvature of the rectum within the pelvis.

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Peritoneal Pouches

Folds of peritoneum within the pelvis, with variations among genders.

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Fetal-Maternal Interface

The structure facilitating material exchange between fetal and maternal blood.

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Pelvic Viscera Orientation

The arrangement of organs within the pelvis, differing between males and females.

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4th week

Critical period in fetal development, marked by significant organogenesis and differentiation.

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6th week

Significant development of glands and related structures.

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Glands

Groups of cells that release specific substances in the body.

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Pelvic Viscera

Organs within the pelvis, including reproductive and digestive systems, with their supporting structures.

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Superior

Situated above or at a higher level.

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Chromaffin cells

Specialized post-synaptic autonomic nerve cells that synthesize and secrete adrenaline and noradrenaline.

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Fetal cortex

An early stage of the adrenal cortex formed during development.

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Adult cortex

The fully developed adrenal cortex formed later in development.

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Mesothelial cells

Cells that line the coelom and differentiate during adrenal cortex development.

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Adrenal cortex development

Two-wave process involving mesothelial cells forming the fetal and then adult cortex.

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Pre-synaptic sympathetic nerve

Nerve that releases ACh directly onto chromaffin cells.

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Adrenaline/Noradrenaline synthesis

Chromaffin cells produce and secrete these hormones.

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Fetal vs. Adult cortex difference

Fetal cortex is a precursor to the adult cortex and eventually disappears after birth.

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Calcified Pineal Glands

Calcification in the pineal gland, a structure in the brain, commonly seen in adult individuals, especially females.

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Precocious Puberty

Early onset of puberty; development of secondary sexual characteristics before the typical age.

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Pineal Tumors

Abnormal growths in the pineal gland. Can sometimes lead to precocious puberty.

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Pharyngeal Arches

Structures in the embryo that eventually form parts of the face and neck.

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Thyroid Development

The thyroid gland develops from a structure associated with the tongue, then migrates to the neck.

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Endocrine Gland Development

Development of endocrine glands affects their adult structure and function.

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Pituitary Gland Origin

Anterior pituitary from surface ectoderm (Rathke's pouch), posterior from forebrain.

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Rathke's Pouch

Ectodermal pouch forming the anterior pituitary.

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Posterior Pituitary Origin

Derived from the forebrain (neural tube ectoderm).

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Endocrine Organs

Organs producing hormones transported via the bloodstream to target cells.

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Hypothalamus

Brain region regulating the pituitary gland's function.

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Pineal Gland

Endocrine gland, part of the brain.

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Pharyngeal Arch Glands

Endocrine glands originating from pharyngeal arches.

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Adrenal Gland

Dual-origin gland, cortex & medulla.

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Endocrine Pancreas

Part of the pancreas producing hormones.

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Embryonic Endocrine Differences

Variations in the development of different endocrine glands.

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Carnegie Stage 13

Embryonic stage (28-32 days gestation)

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Surface Ectoderm

Outer layer of germ cells.

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Stomodeum

Invagination of surface ectoderm

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Adult Endocrine Function

How the gland's development affects its adult function.

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Surface Ectoderm

The outermost germ layer in early embryonic development, forming structures like skin and epidermis.

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Endoderm

The innermost germ layer forming the lining of the digestive tract and associated organs.

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1st Order Branches

The initial divisions of branches or structures in a developmental system or structure, like in nerves.

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2nd Order Branches

Subdivisions of the first-order branches in a developmental or structural hierarchy, like nerves.

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3rd Order Branches

Further subdivisions of the second-order branches, still part of a structural or developmental hierarchy, like in nerves.

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Thyroid Follicles Function

Thyroid follicles become functional around 10-11 weeks of gestation, crucial for lung maturation.

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Thyroid Hormone (TH) Effect on Lungs

TH accelerates alveolar development and increases lung compliance promoting development.

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Maternal Iodine Deficiency

Low maternal iodine intake negatively affects fetal thyroid development, impacting neural hormone development

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Late Fetal TH Impact

Increased TH in the late fetal period stimulates brown fat development, enabling non-shivering thermogenesis.

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Axolotl Lung Development

Axolotls, Mexican salamanders, can develop lungs in fluctuating aquatic environments.

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Thyroid Gland Location

The thyroid gland is located in the neck and upper thorax. Its location is important during development and throughout life.

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Iodine Importance

Iodine is crucial for proper thyroid function, and thyroid hormones are important for various bodily functions, particularly fetal and brain development.

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Fetal Thyroid Development

Fetal thyroid development occurs to support various processes and is crucial for maturation of bodily function.

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Pharyngeal arch contributions

Different parts of the head and neck develop from pharyngeal arches, including structures like the thyroid, parathyroid, and thymus.

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Parathyroid development

Parathyroid glands develop from pharyngeal pouches, specifically 3rd and 4th pouches.

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Thymus development

The thymus arises from the 3rd pharyngeal pouch.

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Thyroid C-cells

C-cells of the thyroid originate from the ultimobranchial body, which itself develops from the 4th pharyngeal pouch.

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Adrenal gland origin

Adrenal glands have a dual origin, from neural crest cells and lateral plate mesoderm.

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Medullary cells

Medullary cells (chromaffin cells) are derived from neural crest cells within the adrenal glands.

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Calcitonin release

Calcitonin release occurs in response to high calcium levels, helping regulate calcium homeostasis.

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Thyroid release

The thyroid release calcitonin to regulate calcium in the body.

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Fetal adrenal cortex development

The fetal adrenal cortex is crucial for fetal development and regulates lung maturation, gut function, parturition, & maternal adaptations.

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Fetal adrenal zones

The fetal adrenal cortex contains zones (glomerulosa, fasciculata, reticularis) that develop at different times and have specific functions related to hormone secretion, mainly in postnatal life.

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Fetal endocrine pancreas development

The fetal endocrine pancreas forms from foregut epithelium, differentiates into islet cells (alpha, beta, delta, PP), and becomes functional from week 10 to support glucose homeostasis.

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Endocrine pancreas islet cells

The islet cells in the endocrine pancreas are critical for managing blood glucose levels.

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Fetal adrenal function timing

The zones of the fetal adrenal gland develop and become functional at different stages of pregnancy, particularly in the second and third trimesters.

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Fetal endocrine pancreas influence

The development of the fetal endocrine pancreas can be influenced by common pregnancy issues like poor placental function, maternal diabetes, and fetal malnutrition.

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Importance of fetal islet cell number

The number of islet cells established during fetal development is largely set and important for maintaining glucose homeostasis throughout life.

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Importance of fetal cortex regressing

During early postnatal life, the fetal adrenal cortex tends to regress, while the adult cortex continues to develop in adults

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Aorta constriction

The aorta constricts to redirect blood flow away from inactive kidneys to active tissues.

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Renal blood flow

Blood supply to the kidneys, which can be altered by the aorta's constriction.

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Pre-synaptic neurons

Neurons that transmit signals towards a synapse.

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Post-synaptic neuron

The neuron that receives signals at a synapse.

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Synapse

The connection between two neurons.

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Glomerular filtration rate

The rate at which blood is filtered through the glomeruli in the kidneys; typically about 180 liters per day.

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Renal corpuscle

The functional unit of the kidney, made up of the glomerulus and Bowman's capsule.

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Glomerulus structure

A network of capillaries in the kidney, forming a filter to separate waste from blood.

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Juxtaglomerular cells (JGC)

Modified smooth muscle cells in the afferent arteriole, important in blood pressure regulation and renin release.

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Loop of Henle

A hairpin-shaped part of the nephron that creates a concentration gradient, important for water reabsorption.

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Renal Lobe

A functional unit of the kidney, consisting of the cortex and a medullary pyramid.

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Renal Cortex

The outer layer of the kidney that contains the glomeruli and tubules.

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Medullary Pyramid

The inner part of the kidney, made up of tubules and collecting ducts.

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Nephron

The functional unit of the kidney; filters blood and forms urine.

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Glomerulus

A network of capillaries where blood filtration occurs in the nephron.

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Collecting Duct

A tube that gathers urine from many nephrons and empties into a calyx.

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Minor Calyx

A cup-like structure that collects urine from the papilla of a medullary pyramid.

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Major Calyx

A larger calyx that joins to form the renal pelvis.

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Renal Pelvis

The funnel-shaped structure that connects the major calyces to the ureter.

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Ureter

A tube that transports urine from the kidney to the bladder.

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Counter current multiplication

A process in the kidney that creates a concentration gradient in the medulla by using the flow of filtrate in opposite directions along two adjacent tubes (vasa recta)

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Vasa Recta

A specialized capillary network that surrounds the loop of Henle, enabling nutrient and waste exchange in the renal medulla.

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Medullary Concentration Gradient

A high concentration of salt and other solutes in the renal medulla, enabling the kidney to produce concentrated urine

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Urea Recycling

The process of urea being reabsorbed from the tubules into the interstitial fluid and vasa recta, which is then re-secreted into the tubules in the loop of Henle.

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Efferent Arteriole

The blood vessel that carries blood away from the glomerulus, into the vasa recta, and towards the peritubular capillaries.

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Densa cells

Specialized cells in the juxtaglomerular apparatus that regulate blood pressure and filtration rate.

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Peritubular capillaries

Capillaries surrounding the renal tubules that reabsorb water and solutes.

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Vasa recta

Specialized capillaries in the medulla of the kidney that maintain the concentration gradient for water reabsorption.

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Medullary rays

Structures in the kidney medulla that contain collecting ducts and extend toward the cortex.

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Juxtaglomerular nephrons

Nephrons located in the cortex, involved in blood pressure regulation and fluid balance.

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Cortical nephrons

Nephrons located primarily in the cortex, responsible for most of the initial filtration.

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Collecting ducts

Tubules that collect urine from nephrons and transport it to the renal pelvis.

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Glomeruli

Specialized capillary networks where filtration of blood occurs in the nephron.

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Proximal convoluted tubule (PCT)

First segment of the renal tubule, reabsorbing most of the filtered materials.

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Cortical tubules structure and function

Tubules in the kidney's cortex help maintain balance via reabsorption and secretion of substances.

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Proximal convoluted tubule

Highly convoluted portion of the renal tubule.

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Distal tubule thick section

Reabsorption and secretion of substances occur in this portion of the renal tubule.

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Distal convoluted tubule (DCT)

Part of renal tubule performing fine-tuning on filtrate via selective reabsorption and secretion.

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Straight tubules

Tubular segments that function in water & solute reabsorption characterized by their straight alignment.

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Gradient of cortical nephron

Refers to a change in concentration of substances from one end of the cortical nephron to the other, crucial to water and salt balance in the medulla.

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Distal Convoluted Tubule (DCT)

Part of the nephron responsible for fine-tuning urine composition. It has fewer microvilli, more cuboidal cells, and less active transport compared to the Proximal Convoluted Tubule (PCT).

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Proximal Convoluted Tubule (PCT)

Part of the nephron where most reabsorption of water, nutrients, and electrolytes occurs. It has microvilli and high active transport.

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Loop of Henle

U-shaped part of the nephron with thin and thick segments. Creates a concentration gradient in the kidney medulla, crucial for water reabsorption.

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Collecting Duct (CD)

Final part of the nephron. It gathers urine from many nephrons and regulates its concentration by controlling water permeability.

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Ureter Histology

Transitional epithelium lines the ureter. It is vital in protection against urine stretch.

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Ureter Function

Moves urine from the kidneys to the bladder via peristalsis.

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Bladder Histology

Smooth muscle sac lined by transitional epithelium, supporting stretch and expansion.

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Bladder Function

Stores urine and expels it through urination.

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Urethra

The tube that carries urine from the bladder to the exterior.

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Urethra Layers

Transitional epithelium near the bladder gives way to stratified squamous epithelium closer to the exterior.

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Peristalsis

Wave-like muscle contractions that move substances along a tube-like structure.

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Retroperitoneal

Describes organs situated behind the peritoneum.

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Micturition

The process of urination.

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Kidney Gross Anatomy

The overall structure of the kidney, including its shape, location, and major parts.

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Renal Histology

The microscopic study of kidney tissue, focusing on its cellular components and organization.

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Nephron Structure

The functional unit of the kidney, responsible for filtering blood and producing urine.

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Urine Formation Process

The sequence of events involved in forming urine, from filtration to excretion.

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Ureter Anatomy

The structure of the tube connecting the kidneys to the bladder to transport urine.

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Aorta's role in kidney blood flow

The aorta controls blood flow to the kidneys; adjusting flow depends on the kidneys' activity and redirects blood during exertion.

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Synapse location (kidneys)

The point where pre-synaptic and post-synaptic neurons for renal function meet and communicate.

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Renal Blood Flow Control

The process by which the body adjusts blood supply to the kidneys to support their functions.

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Cardiac output & tissue blood flow

The amount of blood pumped by the heart per minute, constantly regulated to redirect blood to more active tissues.

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Pre-synaptic/Post-synaptic neurons

Nerve cells before and after the synapse, crucial for transmitting signals and communication for the kidneys.

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Countercurrent Multiplication

A process in the nephron that creates a concentration gradient in the kidney's medulla, allowing for the efficient reabsorption of water and solutes.

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Vasa Recta

Specialized blood vessels surrounding the loop of Henle, crucial for the countercurrent multiplication process.

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Medullary Concentration Gradient

A progressively increasing concentration of solutes from the cortex to the medulla, critical for water reabsorption in the kidney.

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Urea Recycling

A mechanism where urea is reabsorbed and exchanged between the loop of Henle and vasa recta, contributing to the concentration gradient.

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Efferent Arteriole

The blood vessel that carries blood away from the glomerulus, feeding into the vasa recta.

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Macula Densa Cells

Cells in the distal convoluted tubule (DCT) that monitor sodium and chloride ion concentration in the filtrate.

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Juxtaglomerular Cells

Specialized cells in the afferent arteriole of the nephron, releasing renin in response to signals from macula densa cells.

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Renin Release

Secretion of renin by juxtaglomerular cells, triggering a cascade that raises blood pressure, retaining water/sodium.

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Glomerular Filtration Rate (GFR)

The rate at which filtrate is formed in the glomerulus, affected by blood pressure and constriction of arterioles.

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Cortical Nephron

Nephrons located mainly in the kidney cortex, with short loops of Henle, not efficient at concentrating.

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Juxtamedullary Nephron

Nephrons with loops of Henle extending deep into the medulla, crucial for concentrating urine.

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Basement Membrane (Bowman's Capsule)

A thin, filtering layer between the blood and the filtrate in the nephron, crucial for preventing proteins from entering the filtrate.

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Podocytes

Cells in the Bowman's capsule that form filtration slits, controlling what passes into the filtrate.

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Densa Cells

Specialized cells found in the distal convoluted tubule, that regulate sodium and potassium balance, playing a role in blood pressure control within the kidneys.

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Peritubular Capillaries

Capillaries surrounding the renal tubules, involved in reabsorbing substances and secreting waste products, often closer to the CORTEX.

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Vasa Recta

Capillaries in the medulla that participate in the counter-current exchange system, concentrating urine.

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Medullary Rays

Extensions of the cortical tissue that extend into the medulla of the kidney. They are extensions of the renal cortex.

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Juxtaglomerular Nephrons

Nephrons located near the glomerulus, crucial for blood pressure regulation.

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Cortical Nephrons

Nephrons Primarily located in the cortex of the kidney, involved in the filtration and reabsorption of substances.

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Collecting Ducts

Large tubes within the kidney's medulla that collect urine from multiple nephrons, gradually concentrating it.

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Proximal Convoluted Tubules

Part of the nephron that is highly active in reabsorbing valuable substances and secreting waste products. Often found near the glomerulus.

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Glomeruli

Specialized capillary networks within the nephron that filter blood to form urine, situated within Bowman's capsule.

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Distal Convoluted Tubule (DCT)

Part of the nephron involved in fine-tuning of electrolyte balance and pH. Secretion & regulation.

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Countercurrent Exchange

The exchange of substances between fluids flowing in opposite directions, efficient for concentration.

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Renal Tubules

Structures involved in filtering and reabsorbing substances in urine formation process.

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Cortical Tubules

Tubules within the renal cortex involved in early filtering of waste.

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PCT Thick Section

The region of the PCT that is heavily involved in absorption.

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Active Transport in PCT

High level of active transport in proximal convoluted tubule (PCT) for moving substances like salts, water, amino acids, and peptides into blood.

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PCT Microvilli

Microscopic hair-like projections on PCT cells that increase the surface area for absorption, maximizing reabsorption of essential molecules.

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DCT vs PCT cells

Distal convoluted tubule (DCT) cells have fewer microvilli and less active transport compared to the PCT cells. This difference in structure relates to function.

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Loop of Henle Thick segments

The thick ascending and descending segments of the Loop of Henle resemble PCT and DCT in their cellular structure and function.

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Loop of Henle Thin segments

The thin segments of the loop of Henle feature simple squamous epithelium, crucial for water and solute movement.

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Collecting Duct Cells

Cuboidal cells forming collecting ducts are sensitive to aldosterone and adjust water permeability through aquaporin density.

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Ureter Histology

The ureter's lining transitions from transitional epithelium to stratified squamous, protecting against stretch.

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Ureter Peristalsis

The ureter transports urine from the kidney to the bladder via wave-like muscular contractions called peristalsis.

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Urinary bladder histology

The urinary bladder is a smooth muscle sac lined by transitional epithelium, highly folded to accommodate expansion.

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Bladder Detrusor Muscle

The detrusor muscle is a thick muscle layer in the urinary bladder wall, responsible for contraction during urination.

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Retroperitoneal Ureter

The ureter is retroperitoneal, meaning it passes behind the peritoneum in the abdominal cavity.

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Ureter Relations

Ureter relation to gonadal vessels and vas deferens is a key consideration in surgical or anatomical analysis.

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Urethra Sphincters

Sphincters in the male urethra are supported by prostate. They control the flow of urine from the bladder.

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Micturition Reflex

The reflex that triggers the emptying of the bladder when it is full; stimulated by stretch of the bladder wall.

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Aorta

The largest artery in the body, carrying oxygenated blood from the heart to the rest of the body.

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Synapse

The junction between two nerve cells where signals are transmitted.

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Renal Blood Flow

Blood flow to the kidneys.

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Cardiac Output

The amount of blood pumped by the heart per minute.

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Blood Redistribution

Shifting of blood flow from one area to another, prioritizing active tissues.

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Renal Blood Supply Segments

The renal blood vessels are organized in a hierarchical system (segmental, interlobar, arcuate, radiate/interlobular, afferent arteriole) with each segment having a specific function in the filtration of blood.

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Renal Blood Vessels

Critical blood vessels delivering blood to the nephrons for filtration, regulating pressure, and conveying filtered products out of the system.

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Renal Nerve Supply

Vasomotor nerves, mostly sympathetic, regulate blood flow to the kidneys. Parasympathetic (vagus nerve) also contributes influencing glomerular filtration.

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Segmental Renal Blood Supply

Distinct non-anastomosing (no connection between branches of a segment) blood supply to various renal segments - critical for surgical implications.

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Autonomic Renal Regulation

The autonomic nervous system, through sympathetic via aorticorenal pathway and parasympathetic via Vagus, controls kidney function and blood flow, impacting glomerular filtration rate (GFR).

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Glomerular Filtration

The process of filtering blood in the kidneys, creating a filtrate of blood components.

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Renal Corpuscle

A structure in the nephron, consisting of the glomerulus and Bowman's capsule, responsible for initial blood filtration.

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Glomerulus

A network of capillaries within the renal corpuscle, acting as a filter for blood.

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Proximal Convoluted Tubule

A part of the nephron where most nutrients and water are reabsorbed back into the bloodstream.

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Countercurrent Flow

The flow of fluid in opposite directions, in this case within the kidneys; aiding in concentration gradient for reabsorption.

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Renal Lobe

A renal lobe consists of a portion of the cortex and one medullary pyramid.

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Renal Cortex

Outer part of the kidney containing glomeruli, convoluted tubules, and medullary rays.

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Medullary Pyramid

Cone-shaped structures in the kidney medulla, containing nephron loops and collecting ducts.

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Nephron

The functional unit of the kidney, responsible for filtering blood and forming urine.

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Minor Calyx

Cup-shaped structure that collects urine from the papilla of a medullary pyramid.

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Major Calyx

Larger chamber formed by the convergence of minor calyces, collecting urine before renal pelvis.

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Renal Pelvis

Funnel-shaped structure that collects urine from major calyces and connects to the ureter.

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Loop of Henle

Part of the nephron, crucial for concentrating urine by establishing a salt gradient in the medulla.

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Collecting Duct

Tube that collects urine from nephrons and transports it to the minor calyx.

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Papilla

Tip of the medullary pyramid, where urine drains into the minor calyx.

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Countercurrent Multiplication

A process in the kidney's nephron where a concentration gradient is established in the medulla by interacting fluid flows, allowing water reabsorption and urine concentration.

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Vasa Recta

A network of capillaries surrounding the loop of Henle in the kidney, facilitating the countercurrent multiplication process.

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Medullary Concentration Gradient

The increasing concentration of solutes from the cortex to the kidney medulla, crucial for water reabsorption and concentrated urine formation.

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Urea Recycling

Urea's movement between the tubules, interstitial fluid, and vasa recta in the kidney, contributing to the medullary concentration gradient.

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Efferent Arteriole

The blood vessel carrying blood away from the glomerulus toward the vasa recta, which is essential for the countercurrent multiplication.

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Macula densa function

Macula densa cells in the distal convoluted tubule detect sodium and chloride ion concentration, signaling the juxtaglomerular cells.

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Juxtaglomerular cells

Specialized cells in the afferent arteriole that release renin in response to low Na+/Cl- levels.

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GFR

Glomerular Filtration Rate, the rate at which blood is filtered by the glomerulus.

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Cortical Nephrons

Nephrons located primarily in the renal cortex with shorter loops of Henle, less involved in concentrating urine.

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Juxtaglomerular nephrons

Nephrons located near the junction of the cortex and medulla, with longer loops of Henle for maximum urine concentration.

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Podocytes

Specialized cells of the glomerular capsule that form filtration slits with pedicels and slit diaphragms.

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Basement Membrane

Thin, porous barrier between capillary and tubular components of the glomerulus that acts as a filter.

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Slit diaphragm

A loose intercellular connection bridging gaps between the pedicels of podocytes, crucial in glomerular filtration.

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Renal Ontogeny

Development of the kidneys throughout the lifespan, reflecting vertebrate development.

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Pronephros

The first kidney precursor, forming in the neck region.

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Mesonephros

The intermediate kidney precursor, developing in the chest/waist region.

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Metanephros

The permanent kidney that assumes function in adulthood.

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Urogenital Ridge

An area where the paired kidney and gonad primordia form.

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Intermediate Mesoderm (IMM)

Germ layer tissue that develops into structures like kidneys & reproductive organs.

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Kidney Ascent

The process of the kidney moving from its embryonic position to its final adult location.

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Cloacal Septation

Partitioning of the cloaca into distinct openings for urinary, digestive, and reproductive tracts.

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µ reducing developmental error

µ (micro) helps minimize mistakes during development.

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Mesonephros phylogeny

Study of the evolutionary history of the intermediate kidney (mesonephros).

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Reverse osmotic challenge

Adapting to environments with less water and salt than in an organism's body fluids.

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Tubular network & mesonephric duct

Network of tubes linked directly to the intermediate kidney's duct (in some species).

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Signalling ontogenetically

Signalling is necessary for the development of the next kidney (in sequence).

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Mesonephros Function

Filtration and reabsorption of waste products in bony fish and some amphibians.

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Mesonephros vs. Pronephros

Mesonephros has a smaller glomerulus and a larger tubular network, leading to more reabsorption-focused excretion compared to pronephros.

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Metanephros Ontogeny

The definitive kidney in higher vertebrates, developing from the sacral region in week 5.

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Metanephric Duct Origin

The metanephric duct (ureteric bud) grows from the dorsal side of the pelvic mesonephric duct.

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Mesonephric Regression

Thoracic segments of the mesonephros regress by week 5; lumbar segments persist until weeks 10-12.

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Metanephric Ducts

The ducts that develop into the ureters and renal pelvis, extending cranially with the kidney.

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Renal Ascendancy

The process of kidneys moving to their final position in the upper abdomen.

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Accessory Renal Arteries

Additional arteries that supply blood to the kidneys, in addition to the main renal artery.

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Pelvic Kidney

A kidney that fails to ascend to its normal position and remains in the pelvis.

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Horseshoe Kidney

A congenital condition where the kidneys fuse together.

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Renal Calyces

Cup-shaped divisions within the renal pelvis that collect urine from nephrons.

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Major Calyx

Large structures formed where two or more minor calyces converge.

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Renal Pelvis

A funnel-shaped structure that collects urine from the major calyces before it passes into the ureter.

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Subcardinal Venous System

A ladder-like pattern of veins that develop alongside the ascending kidneys.

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Renal Vessels

The arteries and veins that carry blood to and from the kidneys. (Includes arteries, veins, and ureters).

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Kidney Position

Kidneys are positioned on the margins of the psoas and quadratus lumborum muscles, surrounded by perirenal fat, renal fascia, and pararenal fat.

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Renal Support Structures

Renal fascia and pararenal fat provide structural support and cushioning for the kidneys.

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Kidney Upper Pole Position

The upper poles of the kidneys rest on the diaphragm and ribs 11 and 12

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Ureter Configurations

Ureters can have extended or normal configurations that influence orientation

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Major Calyces

The major calyces are part of the kidney's drainage system.

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Urogenital Sinus Mesoderm

Embryonic tissue forming the urethra, anal canal, and vagina

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Cloaca Division (6th week)

Separation of the embryonic cloaca into openings for urinary, reproductive, and digestive tracts

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Mesonephric Duct

Embryonic duct related to kidney development and urogenital sinus

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Allantois

Embryonic structure contributing to the bladder and urachus (fibrous ligament)

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Primordial Bladder

Early structure that develops into the bladder

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Urachus

The remnant of the allantois, a fibrous ligament at the apex of the bladder.

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Metanephric Duct

Embryonic duct crucial in kidney placement and ascent; kidney pathway

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Anal Canal, Vagina, Urethra Formation (12th week)

Development of structures during fetal development related to kidney ascent and urinary system.

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µ reducing developmental error

The microenvironment (µ) plays a crucial role in minimizing errors during development.

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Mesonephros phylogeny

The evolutionary history of the middle kidney; the mesonephros.

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Reverse osmotic challenge

Fish adapting to life on land involved changing their osmotic balance to survive in the reduced salt and water environment.

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Signalling ontogenetically

Signalling is essential for the development of subsequent body parts in an organism, which is crucial for copycat systems.

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Tubular network connection

A tubular network connects directly with the mesonephric duct (Wolfian duct) facilitating efficient waste removal and fluid balance.

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Left Kidney Position

The left kidney sits higher than the right due to the liver's presence on the right side.

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Left Renal Vein Length

The left renal vein is longer to cross in front of the aorta.

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Kidney Hilum Location

The hilum of the kidney is approximately at the level of L1/L2 vertebrae.

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Renal Vein Position

The renal vein in the kidney is most anterior.

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Renal Artery Position

The renal artery in the kidney is located behind the vein.

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Metanephric ducts extension

Metanephric ducts grow cranially, extending into what will become the ureters.

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Kidney ascent

Kidneys move upward from their origin to their final position in the upper abdomen.

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Renal blood vessels changes

As kidneys ascend, accompanying blood vessels (arteries and veins) gain, lose, or change paired branches.

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Subcardinal venous system

The veins accompanying the kidneys have a ladder-like appearance during development

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Pelvic kidney

A kidney that fails to ascend during development to its typical position.

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Horseshoe kidney

Two kidneys that fuse together during development.

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Multiple renal arteries

Kidneys can have more than 2 main arteries, usually branching & rejoining.

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Formation of major calyces

Major calyces are formed from several minor calyces, collecting urine before entry into the renal pelvis.

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Accessory vessels

Redundant arteries, veins, or ureters can also develop alongside normal structures

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Renal pelvis formation

The renal pelvis is shaped by the extent (quantity) of the fluid that passes through it.

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Ventral Subcardinal System

System of veins in the trunk that are repurposed and relocated from the left side to the right, originating as part of the original cardinal veins in the trunk.

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Left Renal Vein Length

Longer than its right counterpart; its development is related to the repositioning of blood vessels in the embryo.

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Subcardinal Veins

Veins found in the embryo's trunk, near the kidneys, that eventually are incorporated into other systems via anastomosis.

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Anastomosis of Veins

The connection between different blood vessels, often seen when veins are repositioned or incorporated into different systems.

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Kidney Inferior Position

The kidneys are generally positioned just below the adrenal glands, a significant anatomical location in the trunk.

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Cardinal Veins

Original set of veins in the embryonic trunk that later get modified during development in the body.

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Ventral vs. Dorsal

Descriptions distinguishing directions relative to the front and back of the body.

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Kidney Development

The development of kidneys during the embryonic stage including adaptation to existing blood vessel structures.

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Subcardinal vein anastomosis

The connection between left and right subcardinal veins, forming a ladder-like structure.

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Left cardinal vein obliteration

The left cardinal vein gradually disappears during development, contributing to the right-sided IVC.

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IVC on right side

The inferior vena cava (IVC) develops on the right side of the body due to left cardinal vein regression.

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Left adrenal/gonadal vein joining left renal

Left adrenal and gonadal veins join the left renal vein to reach the IVC via a subcardinal anastomosis.

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Bladder lining origin

The majority of the bladder's lining comes from the hindgut (specifically the cloaca).

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Urogenital Sinus Mesoderm origin

The embryonic tissue that forms the urethra, anal canal, and vagina.

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Cloaca Division (6th week)

The cloaca, a single opening, splits into separate openings for urinary, reproductive, and digestive systems.

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Allantois's role

Forms the bladder and urachus; a remnant of the allantois, which is a fibrous ligament.

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Urinary Tract Formation (12th week)

The urinary tract (urethra, etc.) differentiates after mesonephric kidney development.

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Mesonephric Duct's role

Part of the urogenital sinus mesoderm, relating urogenital structures to the mesonephric ducts (also known as Wolffian ducts).

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Bladder Structure

A smooth muscle sac lined by transitional epithelium, mostly derived from the hindgut.

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Allantois to Bladder

The allantois helps form the bladder, and part remains as fibrous tissue.

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Cloaca Septum Formation

Divides the cloaca into distinct openings (6th week).

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Liver Anatomical Lobes

The liver is divided into four anatomical lobes: right, left, caudate, and quadrate.

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Coronary Ligament

A series of ligaments connecting the liver to the diaphragm and anterior abdominal wall.

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Liver Lobules

Functional units in the liver, composed of hepatocytes arranged around a central vein.

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Bile Duct Sections

Bile flows from the liver via left and right hepatic ducts to the common bile duct, which may combine with pancreatic ducts.

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Falciform Ligament

A ligament that separates the left from the right anatomical lobe of the liver.

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Lesser Omentum

Connects the liver and the stomach, forming one part of the posterior region of the liver.

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Liver Triads

Structures containing bile ductules, portal vein, and hepatic artery, within the liver lobules.

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Histology of the Gallbladder

The gallbladder's histology shows a thick muscular layer and a lining of simple columnar epithelium, adapted for bile storage.

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Liver Lobes

The liver has four anatomical lobes: left, right, caudate, and quadrate.

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Functional Liver Segments

The liver is divided into 8 functional segments, defined by portal triads (hepatic artery, portal vein, and bile duct).

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Principal Line

An imaginary line defining two functional liver lobes, roughly from gall bladder fossa to IVC (inferior vena cava).

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Liver Parenchyma

The functional tissue of the liver, arranged in plates of hepatocytes.

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Liver Sinusoids

Vascular channels between hepatocyte plates, where blood contacts all cells.

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Lobule Concepts

Conceptual models illustrating blood and bile flow patterns in the liver; classical vs. portal lobule.

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Blood/Bile Flow

Blood flows from portal triad to central vein, while bile flows in the opposite direction, towards the triad.

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Liver Acinus

A functional liver unit emphasizing secretory function, with zones based on proximity to hepatic arterioles.

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Hepatocyte Zones

Hepatocytes are categorized into zones (1, 2, 3) based on their distance from hepatic arterioles, and showing different responses to injury.

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Hepatocytes

Liver cells that secrete bile and participate in numerous metabolic functions, forming a large portion of liver tissue.

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Liver Capsule

Protective fibrous covering of the liver; continuous with the connective tissue at Porta Hepatis.

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Biliary System Components

Series of ducts (right, left, common hepatic, cystic, and common bile) transporting bile from liver to duodenum.

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Gallbladder Histology

Concentrates bile by reabsorbing water, with simple columnar epithelium for efficient absorption.

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Pancreas Histology

Exocrine pancreas is composed of tubuloacinar glands with acini (secretory units) and ducts.

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Renal Ontogeny

The developmental process of the kidneys in the human embryo.

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Pronephros

The first, temporary kidney in developing vertebrates, appears in the cervical region.

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Mesonephros

The second-stage kidney, located in the thoracic and lumbar regions, temporary.

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Metanephros

The definitive adult kidney, the final kidney stage.

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Metanephros

The developing kidney that will become the adult kidney.

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Urogenital Ridge

Embryonic structure where kidneys and gonads develop, from intermediate mesoderm

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Pronephros

The first kidney to develop in vertebrate embryos.

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Intermediate Mesoderm

Embryonic tissue source of the urogenital system, including kidneys and gonads.

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Kidney Ascent

The upward migration of the metanephric kidney to its final position.

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Glomerulus

A bundle of capillaries in the kidney that filters blood.

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Cloacal Septation

The process of the cloaca splitting into separate openings for the digestive, reproductive, and urinary systems during development.

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Coelomic Cavity

Body cavity where pronephric duct drains.

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Pronephric Duct

Tube connecting glomerulus to the exterior.

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Human Pronephros Ontogeny

Development of the first kidney in humans.

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Nephrotome

Segment of intermediate mesoderm giving rise to pronephros.

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Adaptation (Pronephros)

Development of a glomerulus allows selective excretion of water.

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Vertebrate Kidney Evolution

Kidney development reflects evolutionary history of vertebrates.

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Water Movement (Pronephros)

Water moves across gradient from body tissues to coelomic fluids, out of body.

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Left Kidney Position

The left kidney is situated higher than the right kidney due to the liver's presence on the right side.

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Left Renal Vein Length

The left renal vein is longer than the right renal vein to cross in front of the aorta.

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Hilum Location

The hilum of the kidney is situated at the level of L1/L2 vertebrae.

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Renal Artery Position

The renal artery is positioned behind the renal vein.

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Ureter Position

The ureter is located behind the renal artery.

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Metanephric Kidney Development

Fetal kidney development, starting around week 6, where the metanephric kidney ascends cranially while the mesonephros (earlier kidney) regresses.

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Amniotic Fluid Production

Fetal kidneys filter blood to create amniotic 'urine', which is swallowed by fetus and helps maintain the integrity of the gut.

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Metanephric Duct Bifurcation

Branching of metanephric ducts, forming collecting tubules, calyces, renal pelvis and ureter.

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Metanephric Blastema

Embryonic tissue that forms the nephrons and collecting ducts of the metanephric kidney, a bilateral structure.

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Fetal Kidney Function

Fetal kidneys filter blood, producing amniotic fluid (waste) in early development, a role later taken over by the maternal kidneys.

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Mesonephros Regression

The mesonephros, an earlier kidney structure, regresses as the metanephric kidney develops.

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Amniotic Fluid Volume

A healthy amount of amniotic fluid suggests correctly functioning fetal kidneys.

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Kidney Ascent

The metanephric kidney ascends cranially during development influenced by the signals from other components.

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Ventral Position

Referring to a structure situated closer to the front of the body or organ.

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Subcardinal Veins

Repurposed veins, originally part of the cardinal vein system, in the trunk.

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Kidney's Under Adrenal

The kidney's location is below the adrenal gland, as seen in cross sections of the body.

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Left Renal Vein Length

The left renal vein is longer than its counterpart, and this is a result of evolutionary developments.

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Anastomosis

A connection between two blood vessels or organs, allowing blood to flow between them.

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Cardinal Veins Obliteration

The original cardinal veins in the trunk, through the course of development, are mostly obliterated.

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Subcardinal System Repurposing

The subcardinal veins are repurposed from the left side to the right side of the body, as part of development.

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Dorsal Position

Describing a structure located on the back of the body or organ.

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Subcardinal Veins

Paired veins that drain the kidneys and gonads, important in development.

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Left Cardinal Vein Obliteration

The left cardinal vein largely disappears during development, contributing to the right-sided IVC.

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Subcardinal Anastomoses

Connections between left and right subcardinal veins, ensuring blood flow.

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Left Adrenal/Gonadal Vein Drainage

Left adrenal and gonadal veins often join the left renal vein.

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Bladder Origin

The bladder lining mainly develops from the hindgut, specifically the cloaca.

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Liver Lobes

Anatomical sections of the liver, including the right, left, caudate, and quadrate lobes, defined by ligaments.

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Coronary Ligaments

Liver ligaments connecting the liver to nearby structures, like the diaphragm and vena cava.

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Liver Lobules

Functional units of the liver, comprising hepatocytes arranged around central veins.

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Biliary Ducts

System of tubes carrying bile from the liver and gallbladder to the duodenum.

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Hepatocytes

Liver cells responsible for metabolic functions like bile production and detoxification.

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Gallbladder

Organ that stores and concentrates bile secreted by the liver.

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Pancreas Exocrine

Part of the pancreas that secretes digestive enzymes into the duodenum.

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Bile Flow

Path of bile from liver to gall bladder to duodenum, a key process in digestion.

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Liver Functional Segments

The liver is divided into 8 functional segments, each defined by portal triads (hepatic artery, portal vein, and bile duct).

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Principal Line of the Liver

An imaginary line marking the boundary between the two functional liver lobes, roughly traces the middle hepatic vein.

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Liver Parenchyma

The functional tissue of the liver, organized into plates of hepatocytes.

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Hepatocyte Parenchyma

The liver's functional cells, forming plates within the liver.

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Liver Sinusoids

Vascular channels between hepatocyte plates, allowing blood contact with all liver cells.

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Liver Lobules

Liver tissue organization; not clearly defined; reflect porto-caval systems.

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Blood & Bile Flow (Liver)

Blood flows triad to central vein; bile moves hepatocytes to triads.

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Bile Canaliculi

Small channels between hepatocytes carrying bile to bile ducts.

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Liver Acinus

Liver functional unit emphasizing secretion; zones based on proximity to portal axis.

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Liver Zones (Acinus)

Acinus zones are based on proximity to hepatic arterioles (Zone 1 closest, Zone 3 furthest).

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Hepatocytes

Liver cells (~80% of liver cells) that secrete bile and process blood.

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Liver Capsule

Fibrous tissue covering the liver, continuous with the supporting CT of porta hepatis; provides support and shape.

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Biliary System Components

Network of ducts carrying bile from liver to duodenum; includes hepatic ducts, cystic duct, common bile duct, etc.

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Study Notes

Pelvic Viscera

  • Pelvic organs are positioned in relation to the pelvic brim and pelvic orientation
  • Male and Female pelvises have similar structural features regarding organs, but in different orientations
  • Peritoneum and pelvic pouches differ between the sexes and include the rectovesical pouch (male) and the rectouterine pouch (female)
  • The rectum, unlike the colon, doesn't have taenia coli, it's divided into thirds; it is continuous with the sigmoid colon
  • The bladder is a smooth muscle sac lined by transitional epithelium, derived from the hindgut; the trigone is the area of ureter input and urethral output

Blood Supply and Inneravtion

  • The internal iliac arteries branch into various arteries supplying the pelvic organs in both males and females
  • There are unique branches to the reproductive organs (e.g., uterine, ovarian, vaginal).
  • The autonomic nerve supply to the pelvic viscera in both sexes: the sympathetic (T10-L2), the parasympathetic, the pudendal nerve.
  • These nerves control pelvic organs' functions and pain signalling.
  • The myometrium, unlike the organs, is not innervated by the autonomic nervous system, but it's more responsive to the hormonal changes

Fetal-Maternal Interface

  • The fetal-maternal interface is at the chorionic plate covered in syncytiotrophoblast epithelium; the basal and chorionic plate provide the fetal-maternal blood barrier
  • Blood from the mother and fetus do not mix
  • Spiral arteries feed the villi with oxygen and nutrients and are critical in transferring hormones from the mother to fetus and waste from the fetus to the mother

Penile Anatomy

  • The corpora cavernosa (high-pressure blood during erection) and corpus spongiosum (patency for sperm) are significant in penile anatomy and function, which includes the tunica albuginea that's white fibrous tissue located around the dorsal vessels of the penis, nerves, veins, and arteries.
  • The penis has superficial (& Dartos) fascia and underlying layers of tissue.

Uterus and Ligaments

  • The uterus has a very important role in the female reproductive process
  • The uterus and its ligaments are amazing; they are held in place through the urogenital hiatus and the sacrospinal ligament.
  • The uterus's ligaments are critical in maintaining placement of the uterus during pregnancy.

Summary of Parts

  • The summary section notes the placement and relationships of the major components of the male and female reproductive tracts and the role of their fascia, pouches, ligaments, and sphincters (internal and external).

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Description

This quiz explores key concepts in male and female pelvic anatomy, including the rectovesical pouch, the peritoneum's role, and the fetal-maternal interface. It covers anatomical orientations, nervous supply, and the function of various structures in reproductive health. Test your knowledge on these crucial aspects of human anatomy.

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