Psychopharmacology

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Questions and Answers

What is the primary role of dendrites in a neuron?

  • Transmit electrical signals to other neurons
  • Regenerate action potentials
  • Protect the neuron from damage
  • Integrate and receive information from other cells (correct)

How does a thick myelin sheath affect the conduction speed of an axon?

  • It increases the risk of ion leakage
  • It reduces the time needed for action potential generation
  • It decreases the efficiency of the electrical signal
  • It improves insulation, allowing faster conduction (correct)

What is the function of the Nodes of Ranvier in relation to myelinated axons?

  • They produce neurotransmitters
  • They increase the number of synaptic vesicles
  • They shrink the distance between axon terminals
  • They serve as points for action potential regeneration (correct)

Which type of neuron structure is primarily responsible for transmitting signals away from the neuron?

<p>Axon (B)</p> Signup and view all the answers

What happens to dendritic spines during prolonged synaptic activity?

<p>They can change size and shape rapidly (A)</p> Signup and view all the answers

Which of the following best describes the function of receptors located on cell membrane proteins?

<p>Act as sites for neurotransmitter binding (C)</p> Signup and view all the answers

What is a possible consequence of increased insulation from a thicker myelin sheath?

<p>Reduced need for signal regeneration (D)</p> Signup and view all the answers

How do ion channels and transporters function within the cell membrane?

<p>They facilitate the movement of charged molecules (D)</p> Signup and view all the answers

At what week after conception does neurogenesis begin?

<p>Week 5 (D)</p> Signup and view all the answers

What significant event occurs during the 23rd prenatal week?

<p>Connections between neurons begin to form (C)</p> Signup and view all the answers

How many neurons are typically present at birth?

<p>100 billion (B)</p> Signup and view all the answers

Which structure does the central nervous system begin as during development?

<p>Neural tube (D)</p> Signup and view all the answers

Why are animal models used in behavioral pharmacology research?

<p>They allow for rigorous control of living conditions (B)</p> Signup and view all the answers

Which of the following best describes neuropsychopharmacology?

<p>Understanding the role of neurochemicals in behavior and mood (D)</p> Signup and view all the answers

Which techniques are essential for assessing the CNS in neuropharmacology?

<p>Multiple neurobiological techniques (C)</p> Signup and view all the answers

What role do behavioral measures play in the context of neuropsychopharmacology?

<p>They help to understand neurochemical basis and drug impacts (D)</p> Signup and view all the answers

What does operant conditioning primarily involve?

<p>Animal learns a response to achieve rewards. (B)</p> Signup and view all the answers

In a fixed-ratio schedule, reinforcement is provided after what?

<p>A fixed number of responses. (A)</p> Signup and view all the answers

What are analgesic drugs expected to do in the context of operant analgesia testing?

<p>Raise the aversive threshold. (C)</p> Signup and view all the answers

What does the tail-flick test measure in animal studies?

<p>Pain response to heat stimulus. (C)</p> Signup and view all the answers

What is the purpose of training an animal to press a lever to turn off a foot shock?

<p>To learn negative reinforcement. (D)</p> Signup and view all the answers

What does effective spatial memory in a radial arm maze indicate?

<p>The animal remembers previous visits to arms. (A)</p> Signup and view all the answers

How can drugs influence animal behavior in maze tests?

<p>By altering memory or behavior. (B)</p> Signup and view all the answers

Which statement is true regarding reinforcement schedules in operant conditioning?

<p>Fixed-ratio schedules provide reinforcement after a set number of responses. (B)</p> Signup and view all the answers

What role do receptor antagonists play in ligand-receptor interactions?

<p>They prevent active ligands from binding to the receptor. (B)</p> Signup and view all the answers

How do partial agonists behave compared to full agonists?

<p>They have lower efficacy than full agonists. (C)</p> Signup and view all the answers

What effect does a competitive antagonist have on the EC50 of an agonist?

<p>It shifts the EC50 value higher, decreasing potency. (C)</p> Signup and view all the answers

What distinguishes noncompetitive antagonists from competitive antagonists?

<p>Noncompetitive antagonists reduce the effect without competition. (C), Competitive antagonists can be displaced by excess agonists. (D)</p> Signup and view all the answers

What happens to the maximum effect (Emax) of an agonist in the presence of a competitive antagonist?

<p>It remains unchanged but requires a higher dose. (D)</p> Signup and view all the answers

How does ligand binding to a receptor influence the receptor?

<p>It initiates a series of intracellular events. (A)</p> Signup and view all the answers

Full agonists, such as natural neurotransmitters, are characterized by their ability to:

<p>Initiate the maximum biological response. (B)</p> Signup and view all the answers

What is a common effect of increasing neurotransmitter synthesis on synaptic function?

<p>It enhances synaptic function. (A)</p> Signup and view all the answers

What role does TH play in catecholamine synthesis?

<p>TH determines the overall rate of DA or NE synthesis. (B)</p> Signup and view all the answers

How does high catecholamine level affect TH activity?

<p>It inhibits TH, reducing catecholamine synthesis. (B)</p> Signup and view all the answers

Which precursor is known to increase catecholamine synthesis?

<p>L-DOPA (A)</p> Signup and view all the answers

What is the function of VMAT in catecholaminergic neurons?

<p>To recognize and transport monoamines into vesicles. (B)</p> Signup and view all the answers

What behavioral activation is associated with increased catecholamine release?

<p>Increased locomotor activity leading to stereotyped behaviors. (A)</p> Signup and view all the answers

What is the primary effect of autoreceptor stimulation on catecholamine release?

<p>It inhibits the release of catecholamines. (D)</p> Signup and view all the answers

What occurs to catecholamines after their release into the synaptic cleft?

<p>They can be repackaged or broken down. (A)</p> Signup and view all the answers

What effect does α-methyl-para-tyrosine (AMPT) have on catecholamine synthesis?

<p>It blocks TH and prevents catecholamine synthesis. (B)</p> Signup and view all the answers

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