Honors Biology Exam Review

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Questions and Answers

What is a key component of a controlled experiment?

  • Use of multiple independent variables
  • Hypothesis and conclusion only
  • Randomly selected subjects
  • Independent variable and dependent variable (correct)

Which of the following statements best describes a scientific theory?

  • A widely accepted fact supported by minimal evidence
  • A conclusion based solely on personal belief
  • An unproven assumption about natural phenomena
  • A supported conclusion that is not widely accepted (correct)

Which of the following practices is NOT emphasized for success on the exam?

  • Reviewing key diagrams and vocabulary
  • Replicating experiments and peer evaluations
  • Focusing on definitions without context (correct)
  • Practicing calculation and unit analysis

What will happen if a student provides no work for calculation questions on the exam?

<p>They receive no points for that question (A)</p> Signup and view all the answers

Which of the following will NOT be permitted during the exam?

<p>Shared calculators among students (A)</p> Signup and view all the answers

How many multiple-choice questions should students expect on the exam?

<p>75 to 100 questions (D)</p> Signup and view all the answers

What is the consequence of an incorrect conversion factor on the exam?

<p>It results in a loss of 2 points (B)</p> Signup and view all the answers

Which of the following strategies is recommended for exam preparation?

<p>Having a clear understanding of scientific inquiry (D)</p> Signup and view all the answers

What is the main role of transcription in the central dogma of molecular biology?

<p>Synthesis of RNA from DNA (C)</p> Signup and view all the answers

Which best defines evolution?

<p>Change in the genetic makeup of a population over time (C)</p> Signup and view all the answers

What causes genetic variation within a population?

<p>Mutation in DNA (B)</p> Signup and view all the answers

How do hydrogen bonds primarily form in water molecules?

<p>Between hydrogen and oxygen atoms in different molecules (A)</p> Signup and view all the answers

Carbon's versatility in forming diverse organic molecules is due to its ability to:

<p>Form four covalent bonds with other atoms (D)</p> Signup and view all the answers

What are the components of a nucleotide in nucleic acids?

<p>Sugar, phosphate, and nitrogen base (A)</p> Signup and view all the answers

How do saturated and unsaturated fatty acids differ structurally?

<p>Saturated fatty acids contain single bonds with maximum hydrogen (C)</p> Signup and view all the answers

What is one key distinction between prokaryotic and eukaryotic cells?

<p>Eukaryotic cells possess a nucleus (B)</p> Signup and view all the answers

What is a primary observation of cell theory?

<p>Cells are the basic unit of life (B)</p> Signup and view all the answers

What structural feature distinguishes RNA from DNA?

<p>RNA contains ribose sugar, while DNA contains deoxyribose (B)</p> Signup and view all the answers

Which statement correctly describes mutations?

<p>Mutations can lead to changes in protein structure (D)</p> Signup and view all the answers

What does a phylogenetic tree illustrate?

<p>The evolutionary relationships among species (C)</p> Signup and view all the answers

What type of bond is formed between water molecules, due to their polarity?

<p>Hydrogen bonds (B)</p> Signup and view all the answers

What defines a nucleotide in DNA?

<p>A sugar, a phosphate group, and a nucleobase (A)</p> Signup and view all the answers

Which of the following organelles is NOT a part of the endomembrane system?

<p>Ribosome (D)</p> Signup and view all the answers

Which process describes the movement of water molecules toward a region of higher solute concentration?

<p>Osmosis (A)</p> Signup and view all the answers

In the context of the first law of thermodynamics, what best explains the transformation of energy in photosynthesis?

<p>Sunlight energy is converted into chemical energy (A)</p> Signup and view all the answers

Which statement accurately describes the structure of a phospholipid?

<p>It consists of two fatty acids and one phosphoric acid (A)</p> Signup and view all the answers

Which of the following best describes passive transport?

<p>It occurs along the concentration gradient (D)</p> Signup and view all the answers

What key feature distinguishes eukaryotic cells from prokaryotic cells?

<p>Presence of a nucleus (A)</p> Signup and view all the answers

What best explains the term 'entropy' in the context of living organisms?

<p>The inevitable tendency toward chaos and disorder (C)</p> Signup and view all the answers

Which nitrogen bases are complementary in DNA?

<p>Adenine and Thymine (D)</p> Signup and view all the answers

What best describes exons in RNA processing?

<p>Coding sequences that remain in the mature mRNA (D)</p> Signup and view all the answers

What defines the term 'central dogma' in molecular biology?

<p>Information flows from DNA to RNA to protein (A)</p> Signup and view all the answers

What is the result of denaturing a protein?

<p>Its structure changes, potentially affecting function (A)</p> Signup and view all the answers

What process involves the selective permeability of cell membranes?

<p>Osmosis and facilitated diffusion (A)</p> Signup and view all the answers

Which of the following statements regarding metric prefixes is accurate?

<p>Kilometers and millimeters differ by a factor of 1000 (C)</p> Signup and view all the answers

What is the primary function of the rough endoplasmic reticulum?

<p>Synthesis of proteins (D)</p> Signup and view all the answers

Which part of the endomembrane system is responsible for packaging and further modifying new molecules?

<p>Golgi apparatus (C)</p> Signup and view all the answers

What type of bond connects the nitrogen bases in a DNA molecule?

<p>Hydrogen bonds (A)</p> Signup and view all the answers

Which of the following nucleotides is formed from deoxyribose sugar?

<p>Adenine (A)</p> Signup and view all the answers

Which nitrogen bases pair together in DNA through hydrogen bonding?

<p>Adenine and Thymine (C)</p> Signup and view all the answers

What does the term 'antiparallel' refer to in DNA structure?

<p>One strand runs 5' to 3', the other runs 3' to 5'. (B)</p> Signup and view all the answers

What is the role of mRNA in the process of protein synthesis?

<p>To transmit genetic information for protein synthesis (A)</p> Signup and view all the answers

What do exons and introns represent in gene structure?

<p>Exons are coding, introns are non-coding sequences. (A)</p> Signup and view all the answers

In the endosymbiotic theory, what is proposed about mitochondria and chloroplasts?

<p>They were once free-living prokaryotes taken up by a larger cell. (D)</p> Signup and view all the answers

Which component of a nucleotide distinguishes it from other nucleotides?

<p>The nitrogen base (A)</p> Signup and view all the answers

What is the function of lysosomes within a cell?

<p>To break down waste materials (A)</p> Signup and view all the answers

Which of the following correctly describes RNA compared to DNA?

<p>RNA contains ribose sugar, DNA contains deoxyribose sugar. (C)</p> Signup and view all the answers

Which process is used for the conversion of units in scientific measurements?

<p>Unit analysis using conversion factors (A)</p> Signup and view all the answers

What is the most distinguishing feature of the Golgi apparatus?

<p>It is a stack of flattened membranes. (A)</p> Signup and view all the answers

What is the primary difference between prokaryotic and eukaryotic cells regarding their genetic material?

<p>Prokaryotic cells contain their DNA in a nucleoid. (D)</p> Signup and view all the answers

Which structure in a eukaryotic cell is responsible for isolating its genetic material?

<p>Nucleus (B)</p> Signup and view all the answers

How do phospholipids orient themselves in a membrane structure?

<p>Hydrophobic tails hide from water, while heads face the water. (B)</p> Signup and view all the answers

What is the main characteristic of passive transport?

<p>It occurs spontaneously without the use of energy. (D)</p> Signup and view all the answers

Which type of passive transport specifically refers to water movement across a membrane?

<p>Osmosis (D)</p> Signup and view all the answers

What does 'down the concentration gradient' mean?

<p>Movement from high to low concentration. (B)</p> Signup and view all the answers

In an isotonic solution, what happens to an animal cell?

<p>It maintains normal shape and function. (A)</p> Signup and view all the answers

What is the effect of a hypertonic solution on a plant cell?

<p>The cell undergoes plasmolysis. (B)</p> Signup and view all the answers

What defines a concentration gradient?

<p>A difference in the concentration of a substance across a space. (C)</p> Signup and view all the answers

What happens to an animal cell in a hypotonic solution?

<p>It bursts due to excessive water intake. (D)</p> Signup and view all the answers

Which statement about facilitated diffusion is correct?

<p>It utilizes transmembrane proteins to assist movement. (D)</p> Signup and view all the answers

What distinguishes the cell walls of prokaryotic cells?

<p>They contain peptidoglycan in bacteria. (C)</p> Signup and view all the answers

Which property of cell membranes is primarily responsible for their selective permeability?

<p>The hydrophobic and hydrophilic regions of phospholipids. (B)</p> Signup and view all the answers

What occurs during osmosis in cell environments?

<p>Water moves towards areas of low water concentration, not solutes. (D)</p> Signup and view all the answers

Flashcards

Controlled Experiment

A controlled experiment is a scientific study that aims to isolate and test the effect of a specific factor (independent variable) on a measurable outcome (dependent variable). It involves comparing the results of an experimental group, where the independent variable is manipulated, to a control group, where the independent variable remains constant. Other factors (standardized variables) are kept the same across both groups to ensure that any observed difference is due to the independent variable.

Hypothesis

A hypothesis is a testable prediction or proposed explanation for an observation or phenomenon. It's a 'educated guess' about the relationship between variables, formed based on prior knowledge and observations.

Independent Variable

The independent variable is the factor that a scientist intentionally changes or manipulates in an experiment. It's the 'cause' in a cause-and-effect relationship.

Dependent Variable

The dependent variable is the factor that is measured or observed in an experiment. It's the 'effect' in a cause-and-effect relationship. It's what happens as a result of the changes made to the independent variable.

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Standardized Variables

Standardized variables (also called controlled variables) are factors that are kept constant throughout an experiment. They are important because they help ensure that any observed change in the dependent variable is due to the independent variable, not to other uncontrolled factors.

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Control Group

A control group in an experiment serves as a baseline for comparison. It is treated exactly like the experimental group, except for the independent variable, which is not manipulated in the control group. This allows scientists to determine whether the observed changes in the experimental group are directly caused by the independent variable.

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Scientific Theory

A scientific theory is a well-substantiated explanation of some aspect of the natural world that is supported by a large body of evidence and has been repeatedly tested and confirmed through observation and experimentation. It is a highly reliable explanation that has been rigorously tested and is widely accepted within the scientific community.

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Replication

Replication is the process of repeating an experiment multiple times, often with different subjects or under different conditions. This helps to determine the reliability and validity of the results, ensuring that the findings are not due to random chance or errors.

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Prokaryotic DNA Location

DNA is housed in a region called the nucleoid, which is not membrane-bound.

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Eukaryotic DNA Location

Eukaryotic cells have DNA enclosed within a membrane-bound nucleus.

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Organelles in Prokaryotes vs. Eukaryotes

Prokaryotic cells typically lack membrane-bound organelles, while eukaryotic cells have many.

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Phospholipid Bilayer Formation

The hydrophobic tails of phospholipids face inwards, creating a barrier, while the hydrophilic heads interact with the watery environment.

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Selective Permeability

The cell membrane is selectively permeable, meaning only certain molecules can pass through it.

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Passive Transport

Passive transport does not require energy (ATP) and relies on the concentration gradient to move molecules.

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Diffusion

Diffusion is the movement of molecules from an area of high concentration to low concentration.

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Osmosis

Osmosis is the diffusion of water across a selectively permeable membrane from high water concentration to low water concentration.

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Facilitated Diffusion

Facilitated diffusion uses transmembrane proteins to help move molecules down the concentration gradient.

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Concentration Gradient

A concentration gradient is the difference in concentration of a substance across a membrane.

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Down the Concentration Gradient

Down the concentration gradient means moving from a region of high concentration to low concentration.

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Against the Concentration Gradient

Against the concentration gradient means moving from a region of low concentration to high concentration.

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Isotonic Solution

In an isotonic solution, the water concentration inside and outside the cell is the same.

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Hypertonic Solution

In a hypertonic solution, the water concentration outside the cell is lower than inside the cell, causing water to move out of the cell.

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Hypotonic Solution

In a hypotonic solution, the water concentration outside the cell is higher than inside the cell, causing water to move into the cell.

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What is metabolism?

A set of chemical reactions that occur within a cell to sustain life.

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What is evolution?

Changes in the genetic makeup of a population over time.

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What is a mutation?

A change in the DNA sequence.

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What is Replication?

The process of copying DNA to create new DNA molecules.

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What is Transcription?

The process of copying a gene's DNA sequence into RNA.

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What is Translation?

The process of using RNA to create proteins.

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What is Protein Expression?

The process of proteins carrying out their functions and influencing traits.

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What does a phylogenetic tree represent?

A theoretical diagram representing a possible sequence of how species evolved on Earth, showing the evolutionary relationships between organisms.

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How are polar covalent bonds formed?

A bond where electrons are shared unequally, with one atom having a partial negative charge and the other a partial positive charge.

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What makes water a polar molecule?

It has a partially positive side (hydrogen) and a partially negative side (oxygen) due to the unequal sharing of electrons in the covalent bond.

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How do hydrogen bonds form?

Attractive forces between the partially positive hydrogen of one water molecule and the partially negative oxygen of another water molecule.

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What chemical property of carbon makes it so versatile?

Carbon can form four bonds with other atoms, including other carbons, leading to a wide variety of structures and functions.

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What are the component monomers of proteins?

Twenty different amino acids.

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What makes each monomer of proteins unique?

The 'R' group, or side chain, makes each amino acid unique.

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What are the component monomers of nucleic acids?

Nucleotides, composed of a sugar, a phosphate, and a nitrogenous base.

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Levels of Treatment

Levels of treatment are the different values or groups of the independent variable that are tested. It creates the experimental groups.

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Controlled Variable

Controlled variables are factors that are not directly manipulated, but they are kept consistent as much as possible throughout the experiment. They are not the focus of the study, but they could potentially impact the results.

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First Law of Thermodynamics

The first law of thermodynamics states that energy cannot be created or destroyed, only transformed from one form to another. It applies to living organisms since they must obtain energy from their environment as chemical energy, which is then converted into other forms of energy for cellular processes.

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Second Law of Thermodynamics

The second law of thermodynamics states that entropy, a measure of disorder or randomness, always increases within a closed system. Living things are highly ordered and seem to violate the second law of thermodynamics. However, they do not because they are constantly taking in organized molecules from their environment and releasing less ordered molecules as waste, maintaining a constant order within themselves. Eventually, decomposition and decay will return them to the environment, which will increase entropy.

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Entropy

Entropy is a measure of disorder or randomness within a system. The higher the entropy, the more disordered the system. Because organisms are highly ordered, they must constantly take in energy to maintain their ordered state. They release heat and waste products, increasing the entropy of their surroundings as they consume organized energy from their environment.

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Simplest Biological Entity

A cell is considered the simplest biological entity because it is the smallest unit of life that can carry out all the life processes. It is self-contained and can reproduce, grow, and develop independently. It is able to obtain and transform energy for its processes, interact with the environment, and maintain its own internal environment.

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Phospholipid Structure

The structure of a phospholipid consists of a hydrophilic head (phosphate and glycerol) and two hydrophobic tails (fatty acid chains). When in water, the hydrophobic tails aggregate together to minimize contact with the water while the hydrophilic heads face the water.

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Central Dogma of Molecular Biology

The central dogma of molecular biology describes the flow of genetic information within a biological system. It describes how DNA is transcribed into RNA, which is then translated into proteins. These proteins are responsible for carrying out the essential functions of the cell.

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What is the function of the nucleus?

The organelle responsible for containing and replicating genetic material, as well as producing RNA.

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What is the nuclear envelope?

A double phospholipid bilayer perforated with nuclear pores that encloses the nucleus.

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What is the endoplasmic reticulum?

A network of membranes involved in the synthesis and transport of molecules, consisting of rough and smooth ER.

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What is the lumen?

The internal compartment of the ER where synthesis takes place, such as protein synthesis.

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What is the rough endoplasmic reticulum (RER)?

ER studded with ribosomes, responsible for protein synthesis.

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What is the smooth endoplasmic reticulum (SER)?

ER without ribosomes, responsible for lipid and carbohydrate synthesis.

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What is the Golgi apparatus?

A stack of flattened membranes responsible for modifying and packaging new molecules.

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What are transport vesicles?

Small membrane-bound sacs that transport materials between the ER, Golgi, and other parts of the cell.

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What is a lysosome?

An organelle covered with a phospholipid bilayer that contains enzymes for breaking down waste materials.

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What is the endosymbiotic theory?

The idea that mitochondria and chloroplasts were once free-living prokaryotes that were engulfed by a larger cell.

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What is a nucleotide?

The basic building block of DNA, composed of a 5-carbon sugar, a phosphate group, and a nitrogenous base.

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What are the four nitrogenous bases found in DNA?

Adenine (A), Thymine (T), Cytosine (C), and Guanine (G).

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How is genetic information stored in DNA?

The sequence of nucleotides in DNA that carries genetic information.

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What is meant by 'DNA strands have polarity'?

The two strands of a DNA molecule run in opposite directions (5' to 3' and 3' to 5').

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How is DNA's polarity related to the strands in the double helix being 'antiparallel'?

The two strands in the DNA double helix run in opposite directions due to their polarity.

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Study Notes

Exam Review - Honors Biology

  • Exam Format:
    • 75-100 multiple choice questions
    • 25-35 calculation-based questions (metric conversions, unit analysis, graphing, diagrams)
    • No aids permitted during exam
    • Calculator permitted, but not shared
    • Show all work for calculations; no work = no points.
    • There will be a penalty if incorrect conversion factors are used.

Core Concepts & Chapter Review

  • Focus your study on the core concepts, asking questions and practicing with conversion factors, unit analysis, and significant figures.
  • Review material from labs, activities, quizzes, and tests, especially topics you need to master. Use the textbook or supplementary materials. Diagrams may appear on the exam; review those.
  • Review the vocabulary and figures of each chapter.
  • Utilize the core concepts to review the content of the chapters covered.

Chapter 1: Scientific Inquiry

  • Controlled Experiment Components: Observations, questions, hypothesis, independent variable, levels of treatment, dependent variable, standardized variables, control, evaluation of results, conclusions. Replicate with other organisms; results evaluation and publication are considered parts of the scientific process
  • Scientific Theory: A well-supported conclusion, based on multiple pieces of evidence, generally accepted.

Chapter 1: Thermodynamics and Cells

  • First Law of Thermodynamics: Energy is neither created nor destroyed, only transformed.
  • Second Law of Thermodynamics: Entropy (disorder) increases in the universe. Living things maintain order but increase entropy overall in the environment.
  • Cell as Simplest Biological Entity: Independently living entity that exhibits all characteristics of life (energy, reproduction, growth, development, adaptation).

Chapter 1: Cell Features

  • All Cells Share 3 Basic Features: (1) genetic material (DNA); (2) ribosomes (protein synthesis); (3) plasma membrane

Chapter 1: Cell Types

  • Prokaryotic vs. Eukaryotic Cells:
    • Prokaryotic: Small size, no nucleus (nucleoid), no membrane-bound organelles, ancient, cell walls.
    • Eukaryotic: Large size, nucleus, membrane-bound organelles, ribosomes. evolved from prokaryotes

Chapter 1: Domains of Life

  • Three Domains: Bacteria, Archaea, Eukarya

Chapter 1: Central Dogma

  • Central Dogma: DNA → DNA (replication), DNA → RNA (transcription), RNA → protein (translation), protein → trait (expression)
  • Metabolism: Set of chemical reactions in a cell that sustains life

Chapter 1.4 Evolution

  • Evolution: Change in the genetic makeup of a population over time, driven by mutations. Evolution occurs over millions of years.
  • Natural Selection Aspects: (1)Variation within a population, (2) favorable traits lead to (3) survival and reproduction, (4) traits must be in the DNA, (5) environment determines “best” traits for survival.
  • Source of Variation: Mutations of the DNA

Chapter 2: Chemical Bonds & Molecules

  • Polar Covalent Bonds: Unequal electron sharing between atoms (creates partial charges).
  • Water as a Polar Molecule: Unequal electron sharing creates a polar covalent bond. Hydrogen bonding between water molecules is essential.
  • Hydrogen Bonds (form from polar covalent bonds): Attraction between partially charged atoms of water molecules.
  • Carbon Versatility: Four valence electrons allow carbon to form strong, diverse bonds with numerous elements.

Chapter 2: Monomers & Polymers

  • Protein Monomers: 20 amino acids w/unique R-groups.

Chapter 2: Monomers (continued)

  • Nucleic Acid Monomers: Nucleotides composed of 5-carbon sugar, phosphate group, and a nitrogen base.

Chapter 2: DNA & RNA

  • DNA Structure Differences: Double helix, deoxyribose sugar, thymine (T) as a nitrogen base
  • RNA Structure Differences: Single-stranded, ribose sugar, uracil (U) instead of thymine

Chapter 3: Cells

  • Cell Theory: (1) All living things are composed of cells; (2) cells are the basic functional units of life, (3) cells originate from preexisting cells.

Chapter 3: Cell Structure

  • Major Distinctions (Prokaryotic & Eukaryotic): Prokaryotes lack a nucleus and membrane-bound organelles, while eukaryotes have both
  • Differences Between Prokaryotic and Eukaryotic Cells: Prokaryotic cells have no nucleus whereas eukaryotic cells have a nucleus.

Chapter 3: Membrane Structure & Function

  • Phospholipid Structure: Hydrophobic tails (fatty acids) and hydrophilic heads (glycerol, phosphate); create bilayers and liposomes.
  • Selective Permeability: Membrane structure allows small, non-polar molecules through but blocks large and charged ones. Membrane proteins enhance (or block) certain substances from entering.
  • Passive Transport: Movement of molecules from high to low concentration without energy expenditure.
  • Passive Transport Types: (1) Diffusion, (2) Osmosis, (3) Facilitated Diffusion (occurs through a membrane protein).
  • Concentration Gradient: Difference in concentration of molecules across a membrane. “Down” the gradient from high to low. “Against” gradient is low to high, requiring energy.
  • Water Movement: Water moves from low to high solute concentration (in general). Animal cell behavior in different tonicity solutions (isotonic, hypertonic and hypotonic)
  • Endomembrane System: A network of membrane-bound organelles. Involved in protein synthesis, modification, and transport. Include nucleus, nuclear envelope, rough ER, smooth ER, Golgi apparatus, transport vesicles, and lysosomes.
  • Mitochondria & Chloroplasts Origin (endosymbiotic theory): Mitochondria and chloroplasts have similarities with free-living prokaryotes (circular DNA and ribosomes).

Chapter 3: Organelles

  • Nucleus: Contains genetic material and produces RNA; replicated to prepare for cell reproduction.
  • Endoplasmic Reticulum: Synthesis and transport of molecules; rough ER has ribosomes for protein and smooth ER makes lipids and carbohydrates
  • Golgi Apparatus: Modifies, packages, and distributes molecules.
  • Transport Vesicles: Move molecules between organelles.
  • Lysosomes: Contain enzymes to break down molecules or “cell waste”.

Chapter 4: Nucleic Acids

  • Nucleotide Structure: Sugar (deoxyribose), phosphate, nitrogen base (A, T, C, G). Nucleotides bind covalently to form a polymer.
  • DNA Structure: Double helix; nucleotides arranged to form two strands
  • DNA Polarities: 5’ to 3’ on one strand paired with the opposite 3’ to 5’ on the second strand. The two strands are “antiparallel.”
  • Base Pairing: A with T (2 hydrogen bonds) and C with G (3 hydrogen bonds)
  • Genetic Information: Sequence of nucleotides in the DNA that encodes genetic information
  • mRNA Function: Carries genetic information from DNA to ribosomes
  • Exons & Introns: Exons are the expressed parts; introns are the intervening sequences between exons.

Additional Topics

  • Metric Prefixes: Know their values relative to the base unit: EPTGMKHDBODCMMNPFA (largest to smallest)
  • Unit Analysis: Know how to convert units including imperial to metric.
  • Graphs: Graphs should have a title, properly labeled axes, consistent increments and a legend if necessary.
  • Labs: Proper lab gear/ safety equipment is necessary. Review Controlled Experiments and Macromolecules labs' positive and negative controls.

Other Information

  • Transcription and translation graph: Be familiar with the process.
  • Scientific Method: Review variables, and how to answer questions scientifically.
  • Scientific Notation: Review scientific notation (capital then lower case).
  • Phylogenetic trees: Understand the tree of life.
  • Hormones: Understand examples such as Tryptophan.
  • Math problems: Be prepared to answer the types of math problems in the course.
  • Organelles (Exons, Bonds, Polar Molecules, Hypertonic/Hypotonic conditions in cells, Alternative spicing, Gene expression, Denaturing of proteins) review these concepts.

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