40 Questions
What is the typical presenting sign of lymphoma?
A persistently enlarging, non-tender, discrete mass in one lymph node region
What is the characteristic histopathological feature of Hodgkin's lymphoma?
Presence of binucleate cells with abundant cytoplasm and two large nucleoli
What is the radiographic feature of lymphoma of bone?
An ill-defined or ragged radiolucency
What is the clinical feature of lymphoma in the oral cavity?
A nontender, diffuse swelling with a boggy consistency
What is the characteristic of low-grade lesions in Non-Hodgkin's lymphoma?
Well-differentiated, small cells with varying degrees of differentiation
What is the consequence of untreated lymphoma of bone?
Expansion of bone and eventual perforation of the cortical plate
What is the characteristic of Reed-Sternberg cells?
Binucleate cells with abundant cytoplasm and two large nucleoli
What is the progression of lymph node involvement in lymphoma?
Enlarging lymph nodes that become matted and fixed over time
What is the primary purpose of staging a suspected lesion before biopsy?
To prevent distortion of the lesion and lymph nodes
What is the significance of a TX classification in the TNM system?
The primary tumor cannot be assessed
What is the characteristic radiological sign of destruction of underlying bone in carcinoma?
Ill-defined, ragged margin with moth-eaten appearance
What is the definition of a T3 tumor in the TNM system?
Tumor size greater than 4 cm in diameter
What is the significance of perineural invasion in carcinoma?
It may cause paraesthesia
What is the definition of an N2b lymph node in the TNM system?
Clinically palpable, ipsilateral node between 3-6 cm in diameter
What is the purpose of clinical staging in carcinoma?
To predict the prognosis and plan treatment
What is the characteristic clinical feature of an ulcerated carcinoma?
A non-healing ulcer with indurated base
What is a common clinical feature of Ewing sarcoma?
Pain and swelling
What is a characteristic histopathological feature of Kaposi Sarcoma?
Abnormally dense and irregular blood vessels with slit-like spaces
What is the genetic abnormality associated with Ewing sarcoma?
Chromosomal translocation involving EWSR1 and FLI1
What is the function of melanocytes?
To produce melanin for skin, hair, and eye color
What is a common site of involvement in Mucosal Melanoma?
Mandible
What is a characteristic radiological sign of Mucosal Melanoma?
None of the above
What is a common symptom of Kaposi Sarcoma?
Bleeding and ulceration
What is the behavior of Kaposi Sarcoma?
It rarely metastasizes
What is the most significant prognostic factor in oral cancer?
Tumor size and nodal status
Which of the following is a major risk factor that adversely influences prognosis in oral cancer?
Non-cohesive pattern of invasion
What is the most common site of distant metastasis in oral cancer?
Lungs
What is the primary mechanism of tumor-induced death in oral cancer?
Tumor load and blocking of nutrients to normal cells
What is the common complication of radiation therapy in oral cancer?
All of the above
Which of the following is a common comorbidity in patients with oral squamous cell carcinoma?
All of the above
What is the characteristic of lymph nodes with metastasis in oral cancer?
Firm to hard, enlarged, and fixed
What is the treatment approach for oral cancer?
Combination of wide surgical excision and radiation therapy
Which risk factors increase the likelihood of developing osteosarcoma?
Bone irradiation and Paget’s disease of bone
What clinical sign might indicate involvement of the inferior alveolar nerve in mandibular osteosarcoma?
Paraesthesia
What term is used to describe the radiographic 'sunburst' appearance seen in osteosarcomas?
Sub-periosteal bone formation
Which radiographic sign involves symmetric widening of the periodontal ligament space?
Garrington sign
What distinguishes the histopathology of osteosarcoma?
Production of osteoid tissue by malignant mesenchymal cells
Which radiographic presentation is most influenced by the amount of bone formation in an osteosarcoma lesion?
Radiopaque, mixed radiopaque and radiolucent, or entirely radiolucent lesions
Which of the following is a clinical feature of maxillary osteosarcoma?
Nasal obstruction
What is identified by the term Codman’s triangle in osteosarcoma radiographs?
Triangular ridge of new bone formation
This quiz covers the clinical features and histopathology of Hodgkin's lymphoma, including the presenting signs, progression, and characteristic cell appearance.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
