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Hodgkin Disease Staging and Criteria Quiz

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Questions and Answers

What are the B symptoms associated with Hodgkin's disease?

Recurrent drenching night sweats, unexplained, persistent, or recurrent fever, unexplained weight loss of more than 10% of body weight

What are the criteria for a 'bulk' mass in the context of Hodgkin's disease?

10 cm nodal mass or mediastinal mass > 1/3 thorax diameter

What are some adverse prognostic features for stages I & II of Hodgkin's disease according to EORTC data?

More than 3 nodal sites, bulky adenopathy, ESR > 50, presence of B symptoms, invasion into critical organs, male age > 40

Which subtype of B cell malignancies should probably not receive XRT alone?

MC or LD subtype Signup and view all the answers

What type of lymphoma is characterized by Progressive B lymphocyte maturation?

Chronic lymphocytic leukemia Signup and view all the answers

What are the two main types of solid masses in the context of lymphoid malignancies?

Hodgkin and Non-Hodgkin lymphomas Signup and view all the answers

What are the 'B' symptoms associated with Hodgkin's Disease/Lymphoma?

Fever, weight loss, night sweats Signup and view all the answers

What percentage of untreated patients with Hodgkin's Disease/Lymphoma are at risk of dying within 2 to 3 years?

90% Signup and view all the answers

Which type of Hodgkin's Disease/Lymphoma is characterized by neoplastic cells constituting only a small minority of the cells in the affected tissue?

Lymphocyte-predominant Hodgkin’s (LPHD) Signup and view all the answers

What are the most commonly involved lymph nodes in Hodgkin's Disease/Lymphoma?

Cervical and supraclavicular Signup and view all the answers

What percentage of patients with Hodgkin's Disease/Lymphoma have bone marrow involvement?

5% Signup and view all the answers

What is the approximate cure rate of patients suffering from Hodgkin's Disease with chemotherapy?

>80% Signup and view all the answers

What are the B symptoms in Hodgkin's disease?

Fever > 38ºC for three consecutive days, drenching night sweats, unexplained loss of 10% or more of weight in the preceding 6 months Signup and view all the answers

Define Stage III in the Ann Arbor Staging System for Hodgkin's Disease.

Involvement of lymph node regions on both sides of the diaphragm, which may be accompanied by involvement of the spleen or by localized involvement of an extralymphatic organ or site or both. Signup and view all the answers

What is the significance of lacunar cells in nodular sclerosis Hodgkin's lymphoma?

Lacunar cells are characteristic of nodular sclerosis subtype of Hodgkin's lymphoma, indicating a specific histological pattern. Signup and view all the answers

Explain the involvement criteria for Stage IV in the Ann Arbor Staging System for Hodgkin's Disease.

Diffuse or disseminated involvement of one or more extra lymphatic organs or tissues with or without associated lymph node involvement. Signup and view all the answers

What is the role of the spleen in Stage IIIS of the Ann Arbor Staging System for Hodgkin's Disease?

In Stage IIIS, involvement of lymph node regions on both sides of the diaphragm is accompanied by spleen involvement. Signup and view all the answers

What are the adverse prognostic features in Hodgkin's lymphoma?

Adverse prognostic features include B symptoms, advanced stage (IV), significant weight loss, and extranodal involvement. Signup and view all the answers

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