COPY: HIV/AIDS Overview and Structure

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Questions and Answers

What is the primary receptor utilized by SARS-CoV for host entry?

  • Angiotensin-converting enzyme 2 (ACE2) (correct)
  • Nicotinic acetylcholine receptor
  • Serotonin receptor
  • Glutamate receptor

Which protease is NOT involved in the cleavage of the S protein after receptor binding?

  • Cathepsin
  • Furin
  • Protease 7 (correct)
  • TMPRSS2

During which step does the viral genome get released into the host cell?

  • Step 3
  • Step 1
  • Step 4
  • Step 2 (correct)

Where are the viral structural proteins translated and inserted into?

<p>Endoplasmic reticulum (A)</p>
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What process directs the assembly of the virion in the ERGIC?

<p>Interaction with hydrophobic M proteins (D)</p>
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What does HIV primarily attack in the human body?

<p>CD4+ T cells (A)</p>
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Which statement accurately describes AIDS?

<p>It is the final stage of HIV infection. (D)</p>
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What characterizes the chronic HIV (clinical latency) phase?

<p>HIV remains active but at low levels. (B)</p>
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What is a common symptom of AIDS related to opportunistic infections?

<p>Pneumocystis pneumonia. (C)</p>
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What is a key benefit of proper HIV treatment known as ART?

<p>It allows individuals to live longer, healthier lives. (D)</p>
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Which test is used as a confirmatory test for HIV antibodies?

<p>Western Blot. (A)</p>
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What role does reverse transcriptase play in HIV?

<p>Converts viral RNA into DNA. (D)</p>
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How is HIV mainly transmitted between individuals?

<p>Body fluids through sexual contact or sharing needles. (A)</p>
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Why is adherence to Antiretroviral Therapy (ART) crucial?

<p>It prevents the virus from developing resistance. (B)</p>
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Which of the following is a preventive measure against HIV?

<p>Practicing safe sex. (A)</p>
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What occurs during the progression to AIDS if HIV is left untreated?

<p>CD4+ T cells are gradually destroyed. (C)</p>
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What does the CD4 count indicate in HIV patients?

<p>The strength of the immune system. (C)</p>
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Which protein is essential for HIV's entry into target cells?

<p>gp120 (B)</p>
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What is the main purpose of post-exposure prophylaxis (PEP)?

<p>To prevent HIV infection after potential exposure. (D)</p>
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Which of the following statements about the structure of HIV is true?

<p>HIV's envelope proteins are essential for viral replication. (C)</p>
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Which symptom can be associated with neurological effects of HIV?

<p>Memory problems. (A)</p>
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What is the primary receptor that HIV binds to on CD4+ T cells?

<p>CD4 (C)</p>
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Which enzyme is responsible for converting HIV's RNA into DNA inside the host cell?

<p>Reverse transcriptase (B)</p>
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During the assembly of new HIV particles, what component does the virus take from the host cell?

<p>Membrane (C)</p>
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What is the result of continuous activation of the immune system by HIV?

<p>Immune exhaustion (B)</p>
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What stage of HIV infection is often mistaken for the flu, featuring symptoms like fever and swollen lymph nodes?

<p>Acute HIV Infection (A)</p>
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What is the role of CD8+ T cells in response to HIV infection?

<p>To destroy infected cells (B)</p>
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Which of the following correctly describes the fusion process of HIV with the T cell?

<p>The virus fuses its outer layer with the T cell membrane. (C)</p>
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Which immune cells are part of the innate immune response to HIV?

<p>Dendritic cells (D)</p>
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