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Questions and Answers
NRTI drugs usually end in?
NRTI drugs usually end in?
- -UDINE (correct)
- -OSINE (correct)
- -ABINE (correct)
- None of the above
What are the two exceptions to the NRTI ending rule?
What are the two exceptions to the NRTI ending rule?
Abacavir, Tenofovir
PI drugs usually end in?
PI drugs usually end in?
-AVIR
NNRTI drugs usually end in?
NNRTI drugs usually end in?
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Integrase inhibitors usually end in?
Integrase inhibitors usually end in?
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Fusion inhibitors are represented by?
Fusion inhibitors are represented by?
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What is the CCR5 antagonist?
What is the CCR5 antagonist?
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What are pharmacokinetic boosters?
What are pharmacokinetic boosters?
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Name two 'one pill, once daily' INSTI based regimens.
Name two 'one pill, once daily' INSTI based regimens.
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What is a PI based regimen for a new patient?
What is a PI based regimen for a new patient?
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Name two 'one pill, once daily' regimens for NNRTI based treatments.
Name two 'one pill, once daily' regimens for NNRTI based treatments.
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What two types of HIV drugs should never be given alone?
What two types of HIV drugs should never be given alone?
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Study Notes
NRTI Drugs
- NRTI drugs typically end with the suffixes -UDINE, -OSINE, or -ABINE.
- Notable exceptions to the NRTI naming convention include Abacavir and Tenofovir.
PI Drugs
- Protease Inhibitor (PI) drugs generally end in -AVIR.
NNRTI Drugs
- Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) drugs usually conclude with -VIRIDINE, -VIRAPINE, -VIRINE, or -VIRENZ.
Integrase Inhibitors
- Integrase inhibitors are identifiable by their ending in -GRAVIR.
Fusion Inhibitors
- Fusion inhibitors are represented by the drug Enfuvirtide, which can be identified by the suffix -TIDE.
CCR5 Antagonist
- The CCR5 antagonist drug is Maraviroc, often abbreviated as maraviROC.
Pharmacokinetic Boosters
- Ritonavir (RTV) and Cobicistat (COBI) serve as pharmacokinetic boosters in HIV treatment.
One Pill, Once Daily Regimens
- INSTI-based regimens that are taken as a single pill once daily include Triumeq and Stribild.
- NNRTI-based regimens available as one pill once daily are Atripla and Complera.
Recommended Regimens for New Patients
- A PI-based regimen suitable for new patients consists of Prezista combined with Truvada.
Cautions in Treatment
- NRTIs and Boosted PIs should never be administered alone to ensure effective treatment.
- It is recommended to use a combination of two NRTIs in therapy.
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