Histopathological Examination: Tubular Adenoma Diagnosis

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18 Questions

What is the main purpose of a core needle biopsy?

To remove cells and small amounts of surrounding tissue

Which histopathological finding in the excised cecal lesion would be most worrisome regarding cancer risk?

Unclear margins with high-grade dysplasia

What is the main drawback of fine needle aspiration as a method of obtaining tissue samples?

Inadequacy for diagnosis

When doing a punch biopsy, what kind of tissue sample is obtained?

Full-thickness skin specimen

Which special processing technique is used to obtain small fragments of tissues shaved from a surface?

Shave biopsy

What distinguishes excisional biopsy from incisional biopsy?

Size of abnormality removed

What is a key advantage of the Teasing or Dissociation Preparation technique?

Allows examination of cells in the living state.

What distinguishes the Squash Preparation process from Teasing or Dissociation Preparation?

Compression of tissue using another slide or cover glass.

Which technique involves spreading the specimen over the slide surface with a platinum loop?

Smear Preparation

What is a crucial consideration when making smears in Smear Preparation?

Avoid excessively thin or thick smears.

Which process allows the preparation of thick secretions like serous fluids for cytological examinations?

Smear Preparation

What is a distinctive feature of STREAKING technique mentioned in the text?

Rapid and gentle application in a direct or zigzag line across the slide.

What is the purpose of the touch preparation (impression smear) method?

To directly transfer cells to a slide for examination

What type of specimens are suitable for the smear preparation using the 'pull apart' method?

Secretion or sediment drops

What is the temperature range maintained in a cryostat's cold chamber during the freezing process?

-10⁰ -20⁰ C

Which technique allows for immediate diagnosis, especially during intraoperative pathology?

Frozen sections

What type of elements are recommended to be demonstrated using the frozen sections technique?

Lipids and nervous tissue elements

What is the main advantage of the touch preparation (impression smear) method in examining cells?

Enables examination without disrupting intercellular relationships

Learn about the histopathological examination process and the diagnosis of a tubular adenoma with low-grade dysplasia. Understand the potential progression of tubular adenomas to colorectal cancer if left untreated.

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