Histology of Heart and Blood Vessels
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Questions and Answers

What happens when cardiac muscle fibers are lost?

  • They are replaced by adipose tissue
  • They are replaced by new muscle fibers
  • They undergo cell division to regenerate
  • They are replaced by fibrous tissue (correct)

What is the function of the vasa vasorum?

  • To remove waste products from the blood vessels
  • To regulate blood pressure
  • To supply blood to the inner part of the blood vessels
  • To supply blood to the outer part of the blood vessels (correct)

What is the characteristic of the tunica media in large arteries like the aorta?

  • It has a single layer of elastic fibers
  • It consists of simple squamous endothelium
  • It has a fenestrated elastic membrane with 40-70 layers (correct)
  • It is rich in collagen fibers only

What is the type of epithelium lining the tunica intima?

<p>Simple squamous epithelium (B)</p> Signup and view all the answers

What is the main function of the intercalated disc in cardiac muscle fibers?

<p>To prevent separation of muscle cells during heart contraction (A)</p> Signup and view all the answers

What is the consequence of cardiac muscle growth?

<p>It increases in size through hypertrophy (B)</p> Signup and view all the answers

What is the type of muscle present in the tunica media?

<p>Smooth muscle (A)</p> Signup and view all the answers

What is the characteristic of the sarcoplasm in cardiac muscle fibers?

<p>It is acidophilic and contains glycogen granules, mitochondria, and myofibrils (B)</p> Signup and view all the answers

What is the function of the transverse tubule (TT) in cardiac muscle fibers?

<p>To send wide tubules into the myofibrils (A)</p> Signup and view all the answers

What is the characteristic of the Purkinje fibers?

<p>They are modified cardiac muscle fibers forming part of the conducting system (B)</p> Signup and view all the answers

What is the outer layer of the heart composed of?

<p>Simple squamous mesothelium and submesothelial layer of CT (D)</p> Signup and view all the answers

What is the characteristic of the cardiac muscle fibers under a light microscope?

<p>They are short, cylindrical cells with oval, central, mono or binucleated nuclei (D)</p> Signup and view all the answers

What is the characteristic of the intima layer in a medium-sized vein?

<p>Thin and does not contain internal elastic lamina (A)</p> Signup and view all the answers

What is the primary component of the media layer in a medium-sized artery?

<p>Smooth muscle fibers (B)</p> Signup and view all the answers

Which type of blood vessel has a thicker adventitia layer?

<p>Medium-sized vein (D)</p> Signup and view all the answers

What is the primary function of blood capillaries?

<p>Conducting blood from arterioles to venules (D)</p> Signup and view all the answers

What is unique about the lumen of a medium-sized vein?

<p>It is collapsed and usually contains blood after death (D)</p> Signup and view all the answers

What is the characteristic of vasa vasorum?

<p>They are small blood vessels (D)</p> Signup and view all the answers

What is the main characteristic of fenestrated capillaries?

<p>They have endothelium with pores closed by a thin diaphragm (C)</p> Signup and view all the answers

Where are sinusoids typically found?

<p>In bone marrow, spleen, liver, and endocrine glands (B)</p> Signup and view all the answers

What is the function of capillaries?

<p>To exchange gases and nutrients (C)</p> Signup and view all the answers

What is unique about the endothelium in sinusoids?

<p>It is fenestrated without a diaphragm (D)</p> Signup and view all the answers

What is the role of macrophages in sinusoids?

<p>To engulf foreign bodies (A)</p> Signup and view all the answers

What is the diameter range of sinusoids?

<p>5-30 μm (B)</p> Signup and view all the answers

What is the primary function of A-V Shunts?

<p>To regulate body temperature and blood flow (B)</p> Signup and view all the answers

Which of the following is a characteristic of large veins?

<p>They contain only smooth muscles (A)</p> Signup and view all the answers

Where are Vasa Vasorum typically found?

<p>In blood sinusoids (D)</p> Signup and view all the answers

What is a characteristic feature of blood sinusoids?

<p>They have a larger diameter than blood capillaries (B)</p> Signup and view all the answers

What type of A-V Shunts can be found in the skin, ear pinna, and nail bed?

<p>Complicated (B)</p> Signup and view all the answers

Flashcards

Endocardium

Inner layer of the heart wall.

Myocardium

Middle layer of the heart; cardiac muscle.

Epicardium

Outer layer of the heart, simple squamous mesothelium.

Cardiac muscle fibers shape

Short, cylindrical, branching and anastomosing.

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Cardiac muscle fiber type of control

Involuntary.

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Intercalated discs

Structures joining cardiac muscle cells.

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Purkinje fibers

Modified cardiac muscle for conduction system

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Purkinje fibers diameter

Larger than regular cardiac muscle fibers

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Blood vessel types

Arteries, veins, capillaries, sinusoids, arteriovenous shunts

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Arteries types

Elastic (aorta), muscular, arterioles

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Veins types

Venules, medium-sized veins, large veins (inferior vena cava).

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Blood capillary function

Connect arterioles to venules; exchange of substances

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Blood capillary diameter

8-10 μm

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Blood capillary structure

Single layer of endothelial cells on a basement membrane.

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Continuous capillary

Common type of blood capillary.

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Fenestrated capillary

Capillary with pores (fenestrations).

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Blood sinusoids

Dilated, irregular capillaries.

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Blood sinusoids fenestration

Endothelium with pores, no diaphragms.

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Blood sinusoids basement membrane

No basement membrane.

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Blood sinusoids locations

Bone marrow, spleen, liver, endocrine glands.

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Tunica intima

Innermost layer of blood vessel.

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Tunica media

Middle layer of blood vessel, smooth muscle.

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Tunica adventitia

Outermost layer of blood vessel.

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Study Notes

Heart Structure

  • The heart has three layers:
  • Inner layer = endocardium
  • Middle layer = myocardium (formed of cardiac muscle fibers that run in various directions)
  • Outer layer = epicardium (formed of simple squamous mesothelium and submesothelial layer of connective tissue containing coronary vessels)

Cardiac Muscle Fibers

  • Short, cylindrical cells in the heart wall
  • Involuntary
  • Cells are joined together by intercalated discs
  • Intercaled discs prevent separation of muscle cells during heart contraction
  • LM diameter: small (25 µm), branching and anastomosing, show cytoplasmic striation
  • Nuclei: oval, central, mono- or bi-nucleated
  • Sarcoplasm contains glycogen granules, mitochondria, myofibrils, and lipochrome pigments

Purkinje Fibers

  • Modified cardiac muscle fibers
  • Form part of conducting system
  • Larger diameter than cardiac muscle fibers

Blood Vessels

  • Types: arteries, veins, blood capillaries, blood sinusoids, arteriovenous shunts
  • Arteries: large elastic (aorta), medium-sized (muscular) arteries, arterioles
  • Veins: venules, medium-sized veins, large veins (inferior vena cava)

Blood Capillaries

  • Thin blood channels that conduct blood from terminal arterioles to venules (capillary beds)
  • Diameter: 8-10 μm
  • 1 layer of endothelial cells resting on basement membrane
  • Types:
  • Continuous (somatic) capillary
  • Fenestrated capillary
  • Blood sinusoids

Blood Sinusoids

  • Dilated, irregular capillaries (5-30 μm)
  • Endothelium is fenestrated without diaphragms
  • Endothelium rests on reticular connective tissue (no basement membrane)
  • Macrophages extend between endothelial cells to engulf any foreign body
  • Sites: bone marrow, spleen, liver, endocrine glands

General Structure of Blood Vessels

  • Tunica intima: endothelial lining, subendothelial layer, internal elastic lamina
  • Tunica media: smooth muscle, elastin, collagenous and reticular fibers
  • Tunica adventitia: connective tissue, vasa vasorum (small blood vessels)

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Description

A comprehensive quiz on the histology of the heart and blood vessels, covering the inner, middle, and outer layers. Learn about the endocardium, myocardium, and epicardium, and understand their composition and functions.

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