Hepatitis: Causes, Symptoms, and Treatment

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Questions and Answers

A patient presents with jaundice, pruritus, and pale stools. Which of the following underlying mechanisms BEST explains these manifestations in the context of hepatitis?

  • Reduced synthesis of clotting factors resulting in increased capillary permeability.
  • Elevated levels of liver enzymes causing direct irritation of the skin and gastrointestinal tract.
  • Obstruction of bile flow and impaired bilirubin metabolism due to liver inflammation. (correct)
  • Increased production of bile acids leading to systemic vasodilation.

A nurse is caring for a patient with hepatitis A. What is the MOST important instruction to provide to the patient and their family to prevent the spread of the infection?

  • Administering prophylactic antibiotics to all household contacts to prevent secondary infections.
  • Practicing diligent hand hygiene and avoiding sharing utensils or personal items. (correct)
  • Ensuring the patient receives regular blood transfusions to combat anemia.
  • Strictly adhering to a high-protein, low-carbohydrate diet to aid liver regeneration.

A patient with hepatitis C is undergoing treatment. Which laboratory finding would indicate a potential complication related to impaired liver function?

  • Prolonged prothrombin time (PT) and elevated ammonia levels. (correct)
  • Decreased prothrombin time (PT) and international normalized ratio (INR).
  • Elevated hemoglobin and hematocrit levels.
  • Increased serum albumin and decreased ammonia levels.

A patient with chronic hepatitis B is prescribed antiviral medications. What is the PRIMARY goal of this treatment?

<p>Minimizing liver inflammation and preventing progression to cirrhosis or liver cancer. (D)</p> Signup and view all the answers

A patient with hepatitis is experiencing ascites. Which dietary modification is MOST appropriate for managing this condition?

<p>Restricting sodium intake to reduce fluid retention in the peritoneal cavity. (D)</p> Signup and view all the answers

Which medication, commonly available over-the-counter, poses the GREATEST risk of hepatotoxicity if taken in excess or combined with alcohol?

<p>Acetaminophen (A)</p> Signup and view all the answers

A nurse is teaching a patient about preventing the transmission of hepatitis B and C. Which of the following instructions is MOST appropriate?

<p>Avoid sharing razors, needles, or toothbrushes, and use barrier contraception during sexual activity. (B)</p> Signup and view all the answers

A patient with hepatitis reports right upper quadrant (RUQ) pain. What is the MOST likely cause of this pain?

<p>Inflammation and swelling of the liver capsule. (A)</p> Signup and view all the answers

Flashcards

Hepatitis

Widespread liver cell inflammation, commonly caused by viruses, alcohol, or certain medications.

Hepatotoxic Drugs

Medications or substances that can cause liver damage.

Hepatitis A

Transmitted via the fecal-oral route, often due to poor hygiene or contaminated food.

Hepatitis B & C

Transmitted through blood and bodily fluids, potentially leading to chronic infection.

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Jaundice

Yellowing of the skin and eyes due to elevated bilirubin levels.

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Hepatomegaly

Enlargement of the liver, often due to inflammation or scarring.

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Elevated Liver Function Tests

Elevated AST and ALT levels in blood tests.

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Ascites

Fluid accumulation in the abdominal cavity due to low albumin.

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Study Notes

  • Hepatitis refers to the widespread inflammation of liver cells
  • Hepatitis can be caused by alcohol, viruses, or medication

Hepatotoxic Drugs

  • Can cause inflammation of liver cells
  • Acetaminophen
  • Statins
  • Isoniazid for TB
  • NSAIDs

Viral Hepatitis

  • The most common type of hepatitis

Hepatitis A

  • Via the fecal-oral route due to poor hygiene
  • Examples includes homeless shelters, daycares, and poor food handling

Hepatitis B and C

  • Transmitted through blood
  • Can lead to chronic hepatitis
  • From sharing needles, hemodialysis, or blood transfusions
  • Through sexual contact without barrier contraception
  • Perinatal transmission from mother to child during birth by sharing of blood
  • Hepatitis A and C can be treated, but reinfection can occur after exposure

Signs and Symptoms

  • Can be systemic or localized to the liver
  • Fever
  • Anorexia
  • Nausea
  • Malaise
  • Inflamed liver
  • Leads to right upper quadrant (RUQ) pain when palpated
  • Liver dysfunction
  • Bile and bilirubin issues
  • Jaundice
  • Pruritus (itchiness)
  • Pale stool
  • Hepatomegaly (enlargement of liver) because of scarring and fibrosis

Diagnosis

  • Blood tests for antigens
  • Elevated liver function tests
  • Includes AST (aspartate aminotransferase) and ALT (alanine aminotransferase)

Nursing Interventions

  • Antiviral drugs
  • Standard precautions
  • Proper and safe handling of needles
  • Monitoring of liver function tests

Complications

  • Changes in neurological status
  • Bleeding and coagulation problems
  • Fluid retention due to albumin issues
  • Albumin is important for retaining fluid inside blood vessels
  • Albumin problems can lead to fluid leaking out of blood vessels, causing ascites
  • Adequate fluid intake (2 to 3 L/day) and rest

Chronic Infection Treatment

  • Can be managed at home, unless severe liver failure occurs
  • Avoid high-fat foods
  • Eat small, frequent meals

Management of Hepatitis A

  • Refrain from sharing utensils or drinking glasses
  • Practice proper hand hygiene
  • Get Hepatitis A vaccination

Management of Hepatitis B and C:

  • Refrain from sharing needles
  • Use condoms
  • Get Hepatitis B vaccination

Diet Modification

  • High carbohydrate diet
  • High calories
  • Low protein and fat
  • Eat small, frequent meals

Note

  • Most signs and symptoms, interventions, and nursing management strategies are the same for cirrhosis and hepatitis

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