Hepatitis C Virus Replication Cycle

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SumptuousJacksonville
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What is the role of HCV RNA in the host cell?

It serves as a template for viral RNA replication and as messenger RNA for protein production

What is the result of the protein produced by HCV RNA?

The synthesis of a polyprotein that is cleaved by proteases

How do RNA viruses enter host cells?

By attaching to specific receptors and entering the host cell

What is a potential target for drug therapy against HCV?

The HCV RNA polymerase

What is the function of proteases in the HCV life cycle?

To cleave the polyprotein into functional proteins

Study Notes

HCV Life Cycle

  • HCV attaches to a specific receptor and enters the host cell.
  • HCV RNA serves as a template for two purposes:
    • Viral RNA replication
    • Messenger RNA for protein production (translation)
  • The protein produced is a polyprotein that undergoes cleavage by proteases.
  • Two potential drug targets for treating HCV:
    • HCV RNA polymerase
    • HCV RNA protease

This quiz covers the life cycle of Hepatitis C Virus, including its attachment to host cells, RNA replication, protein production, and drug targeting.

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