Podcast
Questions and Answers
What is the role of HCV RNA in the host cell?
What is the role of HCV RNA in the host cell?
- It is cleaved by proteases to produce a polyprotein
- It serves as a template for DNA replication
- It is a receptor for attaching to the host cell
- It serves as a template for viral RNA replication and as messenger RNA for protein production (correct)
What is the result of the protein produced by HCV RNA?
What is the result of the protein produced by HCV RNA?
- The synthesis of a polyprotein that is cleaved by proteases (correct)
- The degradation of the host cell's RNA
- The inhibition of the host cell's immune response
- The production of new viral particles
How do RNA viruses enter host cells?
How do RNA viruses enter host cells?
- By fusing with the host cell membrane
- By producing a polyprotein that interacts with the host cell
- By attaching to specific receptors and entering the host cell (correct)
- By injecting their genetic material into the host cell
What is a potential target for drug therapy against HCV?
What is a potential target for drug therapy against HCV?
What is the function of proteases in the HCV life cycle?
What is the function of proteases in the HCV life cycle?
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Study Notes
HCV Life Cycle
- HCV attaches to a specific receptor and enters the host cell.
- HCV RNA serves as a template for two purposes:
- Viral RNA replication
- Messenger RNA for protein production (translation)
- The protein produced is a polyprotein that undergoes cleavage by proteases.
- Two potential drug targets for treating HCV:
- HCV RNA polymerase
- HCV RNA protease
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