Hepatitis C Virus Replication Cycle

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Questions and Answers

What is the role of HCV RNA in the host cell?

  • It is cleaved by proteases to produce a polyprotein
  • It serves as a template for DNA replication
  • It is a receptor for attaching to the host cell
  • It serves as a template for viral RNA replication and as messenger RNA for protein production (correct)

What is the result of the protein produced by HCV RNA?

  • The synthesis of a polyprotein that is cleaved by proteases (correct)
  • The degradation of the host cell's RNA
  • The inhibition of the host cell's immune response
  • The production of new viral particles

How do RNA viruses enter host cells?

  • By fusing with the host cell membrane
  • By producing a polyprotein that interacts with the host cell
  • By attaching to specific receptors and entering the host cell (correct)
  • By injecting their genetic material into the host cell

What is a potential target for drug therapy against HCV?

<p>The HCV RNA polymerase (C)</p> Signup and view all the answers

What is the function of proteases in the HCV life cycle?

<p>To cleave the polyprotein into functional proteins (D)</p> Signup and view all the answers

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Study Notes

HCV Life Cycle

  • HCV attaches to a specific receptor and enters the host cell.
  • HCV RNA serves as a template for two purposes:
    • Viral RNA replication
    • Messenger RNA for protein production (translation)
  • The protein produced is a polyprotein that undergoes cleavage by proteases.
  • Two potential drug targets for treating HCV:
    • HCV RNA polymerase
    • HCV RNA protease

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