Hepatitis B Virus Replication Process
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Questions and Answers

What is the functional unit of the liver?

  • Central vein
  • Zone 1 of hepatic acinus
  • Hepatocytes (correct)
  • Kupffer cells
  • Which cells in the liver are involved in defense mechanisms and remove debris and bacteria?

  • Sinusoidal endothelial cells
  • Kupffer cells (correct)
  • Bile duct cells
  • Hepatocytes
  • What is the main cause of liver diseases that often never come to medical attention?

  • Alcohol consumption
  • Fatty liver disease
  • Viral hepatitis (correct)
  • Chronic hepatitis
  • Which type of cell death in the liver is unprogrammed and associated with hepatitis?

    <p>Necrosis</p> Signup and view all the answers

    In which zone of hepatic acinus does oxygenated blood from the hepatic artery enter?

    <p>Zone 1</p> Signup and view all the answers

    What is the main characteristic feature of acute hepatitis infection?

    <p>&lt; 6 months duration</p> Signup and view all the answers

    Which virus requires the presence of another virus to infect a host during co-infection?

    <p>Hepatitis D virus</p> Signup and view all the answers

    What is the main target of hepatitis viruses during the replication cycle?

    <p>Hepatocyte cells</p> Signup and view all the answers

    Which hepatitis virus has the shortest incubation period before symptoms appear?

    <p>Hepatitis A virus</p> Signup and view all the answers

    What is the average duration of acute phase infection caused by Hepatitis C virus?

    <p>8 weeks</p> Signup and view all the answers

    Which hepatitis virus has a lipid bilayer and a partial double-stranded DNA genome?

    <p>Hepatitis B virus</p> Signup and view all the answers

    During hepatitis viral replication, what is released into the nucleus after the uncoating of the virus?

    <p>ssRNA</p> Signup and view all the answers

    Which type of infection involves HBV first infecting the host followed by HDV infection?

    <p>Superinfection</p> Signup and view all the answers

    What is the primary mode of transmission for Hepatitis E virus?

    <p>(Contaminated) food or water consumption</p> Signup and view all the answers

    'Partial dsDNA' refers to which type of genetic material found in hepatitis viruses?

    <p>(Partial double-stranded DNA)</p> Signup and view all the answers

    'Fulminant Hep in pregnant women' is most commonly associated with which hepatitis virus?

    <p>(Hepatitis E virus)</p> Signup and view all the answers

    Which enzyme is responsible for converting pre-genomic RNA to DNA in the Hepatitis B virus replication cycle?

    <p>Reverse transcriptase</p> Signup and view all the answers

    During which phase of viral hepatitis infection do flu-like symptoms commonly occur?

    <p>Prodromal Phase</p> Signup and view all the answers

    Which cells release perforin and granzymes to induce cytotoxicity in hepatocytes during hepatitis pathology?

    <p>Cytotoxic T cells</p> Signup and view all the answers

    What occurs in the Exocytosis phase of the Hepatitis B virus replication cycle?

    <p>Matured vesicles leave the hepatocyte</p> Signup and view all the answers

    What is the role of MHC I in hepatitis pathology?

    <p>Presenting antigens on hepatocyte surfaces</p> Signup and view all the answers

    Which enzyme is responsible for synthesizing more DNA in order to allow proper replication of dsDNA in the Hepatitis B virus replication cycle?

    <p>DNA polymerase</p> Signup and view all the answers

    What effect does increased hepatotoxins in an injured liver have on the hypothalamic thermostat?

    <p>Causes fever by triggering prostaglandin release</p> Signup and view all the answers

    How do perforins and granzymes induce apoptosis in hepatocytes?

    <p>Perforins form pores in the hepatocyte membrane, allowing granzymes to enter and trigger apoptosis</p> Signup and view all the answers

    'Jaundice-like' yellow discoloration of skin is primarily due to the deposition of which substance during viral hepatitis infection?

    <p>'Bilirubin'</p> Signup and view all the answers

    What is the main reason for decreased bile flow in the liver during viral hepatitis infection?

    <p>Cholestasis due to reduced bile flow</p> Signup and view all the answers

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