Hepatitis B Virus Replication Process
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Questions and Answers

What is the functional unit of the liver?

  • Central vein
  • Zone 1 of hepatic acinus
  • Hepatocytes (correct)
  • Kupffer cells

Which cells in the liver are involved in defense mechanisms and remove debris and bacteria?

  • Sinusoidal endothelial cells
  • Kupffer cells (correct)
  • Bile duct cells
  • Hepatocytes

What is the main cause of liver diseases that often never come to medical attention?

  • Alcohol consumption
  • Fatty liver disease
  • Viral hepatitis (correct)
  • Chronic hepatitis

Which type of cell death in the liver is unprogrammed and associated with hepatitis?

<p>Necrosis (C)</p> Signup and view all the answers

In which zone of hepatic acinus does oxygenated blood from the hepatic artery enter?

<p>Zone 1 (C)</p> Signup and view all the answers

What is the main characteristic feature of acute hepatitis infection?

<p>&lt; 6 months duration (C)</p> Signup and view all the answers

Which virus requires the presence of another virus to infect a host during co-infection?

<p>Hepatitis D virus (A)</p> Signup and view all the answers

What is the main target of hepatitis viruses during the replication cycle?

<p>Hepatocyte cells (C)</p> Signup and view all the answers

Which hepatitis virus has the shortest incubation period before symptoms appear?

<p>Hepatitis A virus (B)</p> Signup and view all the answers

What is the average duration of acute phase infection caused by Hepatitis C virus?

<p>8 weeks (D)</p> Signup and view all the answers

Which hepatitis virus has a lipid bilayer and a partial double-stranded DNA genome?

<p>Hepatitis B virus (A)</p> Signup and view all the answers

During hepatitis viral replication, what is released into the nucleus after the uncoating of the virus?

<p>ssRNA (D)</p> Signup and view all the answers

Which type of infection involves HBV first infecting the host followed by HDV infection?

<p>Superinfection (A)</p> Signup and view all the answers

What is the primary mode of transmission for Hepatitis E virus?

<p>(Contaminated) food or water consumption (B)</p> Signup and view all the answers

'Partial dsDNA' refers to which type of genetic material found in hepatitis viruses?

<p>(Partial double-stranded DNA) (C)</p> Signup and view all the answers

'Fulminant Hep in pregnant women' is most commonly associated with which hepatitis virus?

<p>(Hepatitis E virus) (B)</p> Signup and view all the answers

Which enzyme is responsible for converting pre-genomic RNA to DNA in the Hepatitis B virus replication cycle?

<p>Reverse transcriptase (A)</p> Signup and view all the answers

During which phase of viral hepatitis infection do flu-like symptoms commonly occur?

<p>Prodromal Phase (D)</p> Signup and view all the answers

Which cells release perforin and granzymes to induce cytotoxicity in hepatocytes during hepatitis pathology?

<p>Cytotoxic T cells (A)</p> Signup and view all the answers

What occurs in the Exocytosis phase of the Hepatitis B virus replication cycle?

<p>Matured vesicles leave the hepatocyte (B)</p> Signup and view all the answers

What is the role of MHC I in hepatitis pathology?

<p>Presenting antigens on hepatocyte surfaces (B)</p> Signup and view all the answers

Which enzyme is responsible for synthesizing more DNA in order to allow proper replication of dsDNA in the Hepatitis B virus replication cycle?

<p>DNA polymerase (D)</p> Signup and view all the answers

What effect does increased hepatotoxins in an injured liver have on the hypothalamic thermostat?

<p>Causes fever by triggering prostaglandin release (D)</p> Signup and view all the answers

How do perforins and granzymes induce apoptosis in hepatocytes?

<p>Perforins form pores in the hepatocyte membrane, allowing granzymes to enter and trigger apoptosis (C)</p> Signup and view all the answers

'Jaundice-like' yellow discoloration of skin is primarily due to the deposition of which substance during viral hepatitis infection?

<p>'Bilirubin' (B)</p> Signup and view all the answers

What is the main reason for decreased bile flow in the liver during viral hepatitis infection?

<p>Cholestasis due to reduced bile flow (D)</p> Signup and view all the answers

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