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Hematopoietic Pathophysiology - Leukostasis and Leukemia Classification

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Hematopoietic Pathophysiology - Leukostasis and Leukemia Classification

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Questions and Answers

What is the specific genetic abnormality associated with Chronic Myeloid Leukemia (CML)?

Turner syndrome

Philadelphia chromosome translocation (correct)

Klinefelter syndrome

Down syndrome

Which phase of the clinical course of CML is characterized by gradual onset?

Blast crisis phase

Chronic phase (correct)

Initial phase

Accelerated phase

What clinical manifestation is commonly associated with thrombocytopenia in leukemia?

High-grade fever

Excessive sweating

Petechiae (correct)

Joint stiffness

What are the constitutional manifestations commonly seen in patients with leukemia?

Low-grade fever, night sweats, weight loss (B) Signup and view all the answers

Which condition is an early sign of the risk of infection in leukemia patients?

Neutropenia (B) Signup and view all the answers

Which organ is commonly affected by hepatomegaly in leukemia patients?

Liver (D) Signup and view all the answers

What is a common cause of lymphadenopathy in Acute Lymphoblastic Leukemia (ALL) patients?

Infiltration of leukemic cells (B) Signup and view all the answers

What symptom could suggest hypogammaglobulinemia in a patient with leukemia?

Increased susceptibility to infections (B) Signup and view all the answers

In leukemia, what is the underlying cause of anemia resulting in symptoms like fatigue and dyspnea?

Low red blood cell count (B) Signup and view all the answers