5 Questions
What is the primary function of hemostasis?
Maintaining fluidity of the blood and limiting blood loss
What is the initial event in the stage of hemostasis involving platelet adhesion, activation, and aggregation?
Exposure of collagen and von Willebrand factor due to injury to the cell membrane
What is the role of prostacyclin (PGI2) in the process of hemostasis?
It is an antiplatelet prostaglandin released by endothelial cells
What is the function of GP Ib receptor in the process of hemostasis?
It binds to von Willebrand factor and causes platelet adhesion into the wall
What is the purpose of platelet adhesion in hemostasis?
To form a plug in the injured blood vessel and prevent blood loss
Study Notes
Hemostasis Overview
- The primary function of hemostasis is to stop bleeding after an injury by forming a blood clot.
Platelet Stage of Hemostasis
- The initial event in the stage of hemostasis involves platelet adhesion, activation, and aggregation.
- Platelet adhesion is the attachment of platelets to the site of injury, specifically to the collagen in the damaged blood vessel wall.
Prostacyclin (PGI2) Role
- Prostacyclin (PGI2) is a potent inhibitor of platelet activation, inhibiting platelet aggregation and adhesion.
GP Ib Receptor Function
- The GP Ib receptor plays a crucial role in the initial adhesion of platelets to the site of injury, facilitating platelet activation and aggregation.
Platelet Adhesion Purpose
- The purpose of platelet adhesion in hemostasis is to form a platelet plug, which is the initial step in the formation of a blood clot and stopping bleeding.
Test your knowledge of drugs used in disorders of coagulation with this quiz on Hematologic Pharmacology. Explore the intricacies of hemostasis and its regulation in maintaining blood fluidity, repairing vascular injury, and preventing excessive blood loss or thrombosis.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
