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Hematologic Pharmacology Quiz

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Questions and Answers

What is the primary function of hemostasis?

Maintaining fluidity of the blood and limiting blood loss (correct)

Ensuring adequate perfusion of vital organs

Repairing vascular injury and promoting thrombosis

Promoting vessel occlusion and preventing blood loss

What is the initial event in the stage of hemostasis involving platelet adhesion, activation, and aggregation?

Binding of platelet membrane receptors to collagen and von Willebrand factor

Exposure of collagen and von Willebrand factor due to injury to the cell membrane (correct)

Release of prostacyclin (PGI2) by endothelial cells

Subsequent activation of platelets

What is the role of prostacyclin (PGI2) in the process of hemostasis?

It activates the platelet membrane receptors

It promotes platelet adhesion to the injured blood vessel

It is an antiplatelet prostaglandin released by endothelial cells (correct)

It causes vessel occlusion and limits blood loss

What is the function of GP Ib receptor in the process of hemostasis?

<p>It binds to von Willebrand factor and causes platelet adhesion into the wall</p> Signup and view all the answers

What is the purpose of platelet adhesion in hemostasis?

<p>To form a plug in the injured blood vessel and prevent blood loss</p> Signup and view all the answers

Study Notes

Hemostasis Overview

The primary function of hemostasis is to stop bleeding after an injury by forming a blood clot.

Platelet Stage of Hemostasis

The initial event in the stage of hemostasis involves platelet adhesion, activation, and aggregation.
Platelet adhesion is the attachment of platelets to the site of injury, specifically to the collagen in the damaged blood vessel wall.

Prostacyclin (PGI2) Role

Prostacyclin (PGI2) is a potent inhibitor of platelet activation, inhibiting platelet aggregation and adhesion.

GP Ib Receptor Function

The GP Ib receptor plays a crucial role in the initial adhesion of platelets to the site of injury, facilitating platelet activation and aggregation.

Platelet Adhesion Purpose

The purpose of platelet adhesion in hemostasis is to form a platelet plug, which is the initial step in the formation of a blood clot and stopping bleeding.

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Description

Test your knowledge of drugs used in disorders of coagulation with this quiz on Hematologic Pharmacology. Explore the intricacies of hemostasis and its regulation in maintaining blood fluidity, repairing vascular injury, and preventing excessive blood loss or thrombosis.