Pharmacology: Hematologic & Cardiovascular Systems

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Questions and Answers

A patient with a history of anemia is prescribed an iron supplement. What common side effect should the nurse educate the patient about?

  • Increased appetite
  • Skin rash
  • Constipation (correct)
  • Tachycardia

A patient is receiving warfarin (Coumadin) for the prevention of blood clots. Which of the following laboratory values is most important for the nurse to monitor?

  • Liver function tests
  • Complete blood count (CBC)
  • Electrolyte levels
  • Prothrombin time (PT) and INR (correct)

A patient is prescribed a thrombolytic medication following an acute myocardial infarction. What is the primary therapeutic effect expected from this medication?

  • Preventing further clot formation
  • Decreasing blood pressure
  • Dissolving the existing blood clot (correct)
  • Reducing cholesterol levels

Epoetin alfa is prescribed for a patient with chronic kidney disease. What laboratory value should the nurse monitor to evaluate the effectiveness of this medication?

<p>Hemoglobin level (D)</p> Signup and view all the answers

A patient is started on an ACE inhibitor for hypertension. What is a common side effect the nurse should educate the patient about?

<p>Persistent dry cough (B)</p> Signup and view all the answers

A patient with heart failure is prescribed digoxin (Lanoxin). What assessment finding would indicate to the nurse that the patient is experiencing digoxin toxicity?

<p>Blurred or yellow-tinged vision (D)</p> Signup and view all the answers

A patient with coronary artery disease is prescribed nitroglycerin. How should the nurse instruct the patient to take this medication for acute angina?

<p>Place one tablet under the tongue and allow it to dissolve. (A)</p> Signup and view all the answers

A patient is receiving amiodarone for the treatment of atrial fibrillation. What potential adverse effect requires ongoing monitoring?

<p>Thyroid dysfunction (D)</p> Signup and view all the answers

A patient with asthma is prescribed albuterol (Ventolin) inhaler. What is the expected therapeutic effect of this medication?

<p>Dilating the bronchioles to improve airflow (B)</p> Signup and view all the answers

A patient is prescribed an inhaled corticosteroid for long-term management of COPD. What instruction should the nurse provide to minimize the risk of oral candidiasis (thrush)?

<p>Rinse the mouth with water after each use (A)</p> Signup and view all the answers

A patient is taking diphenhydramine (Benadryl) for allergic rhinitis. What common side effect should the nurse caution the patient about?

<p>Drowsiness (C)</p> Signup and view all the answers

A patient is prescribed loratadine (Claritin) for seasonal allergies. How does this medication differ from diphenhydramine (Benadryl)?

<p>Loratadine is less likely to cause drowsiness. (A)</p> Signup and view all the answers

A patient is receiving heparin for deep vein thrombosis. What is the antidote for heparin?

<p>Protamine sulfate (A)</p> Signup and view all the answers

After administration of alteplase (Activase) to a patient, the nurse would assess for which of the following potential adverse effects?

<p>Bleeding (A)</p> Signup and view all the answers

A patient with hypertension who also has type 2 diabetes is prescribed lisinopril. What additional benefit, beyond blood pressure control, does lisinopril provide for this patient?

<p>Slows the progression of diabetic nephropathy (B)</p> Signup and view all the answers

Flashcards

Hematologic System

The branch of medicine dealing with blood and blood disorders.

Drug Therapy for Anemia

Medications used to treat conditions characterized by low red blood cells or hemoglobin.

Bleeding Disorders

Conditions that impair the body's ability to stop bleeding, often requiring medical intervention.

Thrombi

Clots formed in a blood vessel that can obstruct blood flow.

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Drug Therapy to Prevent Thrombi

Medications that prevent the formation of blood clots.

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Hematopoiesis

The process of blood cell production occurring in the bone marrow.

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Cardiovascular System

The system comprising the heart and blood vessels important for circulation.

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Drug Therapy for Hypertension

Medications aimed at lowering high blood pressure.

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Heart Failure Drug Therapy

Medications that help manage symptoms and improve heart function in those with heart failure.

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Coronary Artery Disease

Narrowing of coronary arteries, leading to reduced blood flow to the heart.

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Cardiac Dysrhythmias

Abnormal heart rhythms that can affect heart function.

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Lower Respiratory Airflow Disorders

Conditions that restrict airflow to the lungs, such as asthma or COPD.

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Upper Respiratory Disorders

Conditions affecting the nasal passages and throat, like colds or sinus infections.

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Dosage Calculations

Determining the correct drug dosage based on patient-specific factors.

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Study Notes

Week 3: Hematologic System

  • Drug Therapy for Anemia: Includes ferrous sulfate (iron preparation), cyanocobalamin (vitamin B12), and folic acid (vitamin B9).

  • Drug Therapy for Bleeding Disorders: Involves factors VIII and IX (antihemophilic factor), desmopressin (antidiuretic hormone).

  • Drug Therapy to Prevent and Dissolve Thrombi: Includes heparin (factor Xa and thrombin inhibitor), enoxaparin (factor Xa specific inhibitor), warfarin (vitamin K antagonist), aspirin (salicylic/antiplatelet), and clopidogrel (antiplatelet ADP inhibitor), alteplase (thrombolytic).

  • Drug Therapy that Supports Hematopoiesis: Comprises epoetin alfa (erythropoietic growth factor), filgrastim (leukopoietic growth factor), and oprelvekin (thrombopoietic growth factor).

Week 4: Cardiovascular System

  • Drug Therapy for Hypertension: Includes captopril (ACE inhibitor), losartan (ARB), eplerenone (aldosterone antagonist), aliskiren (direct renin inhibitor), doxazosin (alpha-1 blocker), atenolol (beta blocker), reserpine (adrenergic neuron blocker), clonidine (centrally acting alpha-2 agonist), and carvedilol (alpha-beta blocker).

  • Drug Therapy for Heart Failure: Includes hydrochlorothiazide (thiazide diuretic), furosemide (loop diuretic), spironolactone (potassium-sparing diuretic), digoxin (inotropic/cardiac glycoside), dobutamine (inotropic/sympathomimetic), and milrinone (inotropic/phosphodiesterase inhibitor).

  • Drug Therapy for Coronary Artery Disease: Includes atorvastatin (HMG-CoA reductase inhibitor), gemfibrozil (fibrate), and nitroglycerin (nitrate).

  • Drug Therapy for Cardiac Dysrhythmias: Includes quinidine (class IA/sodium channel blocker), procainamide (class IA/sodium channel blocker), lidocaine (class IB/sodium channel blocker), flecainide (class IC/sodium channel blocker), propranolol (class II/beta blocker), amiodarone (class III/potassium channel blockers), and verapamil (class IV/calcium channel blocker).

Week 5: Respiratory System

  • Drug Therapy for Lower Respiratory Airflow Disorders: Includes albuterol (beta-2 agonist), ipratropium (anticholinergic), theophylline (methylxanthine), beclomethasone dipropionate (glucocorticoid), prednisone (glucocorticoid), fluticasone (glucocorticoid), cromolyn (mast cell stabilizer), and montelukast (leukotriene modifier).

  • Drug Therapy for Upper Respiratory Disorders: Includes diphenhydramine (first-generation antihistamine), cetirizine (second-generation antihistamine), phenylephrine (sympathomimetic), codeine (opioid antitussive), dextromethorphan (non-opioid antitussive), guaifenesin (expectorant), and acetylcysteine (mucolytic).

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