30 Questions
Which type of infection is associated with superinfection of HDV?
Chronic
What is the prevailing genotype of HDV in Europe?
Genotype 1
Which of the following is a possible mode of transmission of HDV?
Sexual contact
Which cellular enzyme is responsible for HDV genomic RNA replication?
RNA polymerase II
What is the morphology of HDV?
Enveloped, spherical, and pleiomorphic
How does HDV enter the cells?
Mediated by HBsAg protein
Which type of disease can superinfection of HDV cause?
Severe acute disease
What is the prevailing genotype of HDV in Europe?
Genotype 1
What are the possible modes of transmission of HDV?
Injecting drug use
What is the only protein encoded by the HDV genome?
HDAg
What is the morphology of HDV?
Spherical and pleiomorphic
What is the replication cycle of HDV?
Genomic RNA replication is operated by viral RNA polymerase
What is the most common genotype of HDV in Europe?
Genotype 1
Which type of exposure can transmit HDV through sex contact?
Permucosal exposure
What is the characteristic histological feature of acute HDV infection in the liver?
Presence of inflammatory cells in the parenchyma and portal areas
Which protein is associated with the viral genome and is the only protein encoded by the HDV genome?
HDAg protein
What is the morphology of HDV?
Spherical and slightly pleiomorphic
What is the replication cycle of HDV?
Genomic RNA replication in the nucleus operated by cellular RNA polymerase II followed by cuts and autocatalytic ligation of genome and antigenome to produce the mRNA encoding S and L forms of HDAg
Which protein is associated with the HDV viral genome and is the only protein encoded by the HDV genome?
HDAg protein
What is the morphology of HDV?
Spherical and slightly pleiomorphic
What is the replication cycle of HDV?
Genomic RNA replication in the nucleus operated by cellular RNA polymerase II
Which type of exposure can transmit HDV through sex contact?
Permucosal exposure
What is the prevailing genotype of HDV in Europe?
Genotype 1
What is the type of infection associated with superinfection of HDV?
Chronic infection
Which type of HDV infection is associated with chronic disease?
Superinfection
What is the prevailing genotype of HDV in Europe?
Genotype 1
Which type of exposure can transmit HDV through injecting drug use?
Percutaneous exposure
Which protein is associated with the HDV viral genome and is the only protein encoded by the HDV genome?
HDAg protein
What is the possible mode of entry of HDV into the cells?
Mediated by HBsAg
What is the morphology of HDV?
Spherical, slightly pleiomorphic envelope
Test your knowledge on HDV families and their genome structure, including their circular RNA negative polarity and ribozyme activity. Learn about the HDAg protein, which is the only protein encoded by the HDV genome, and the replication cycle of HDV, which may be mediated by HBsAg. Take the quiz now!
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