HDV Families and Genome Structure Quiz
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Questions and Answers

Which type of infection is associated with superinfection of HDV?

  • Acute
  • Chronic (correct)
  • Both acute and chronic
  • None of the above
  • What is the prevailing genotype of HDV in Europe?

  • Genotype 2
  • Genotype 3
  • Genotype 1 (correct)
  • Genotype 4
  • Which of the following is a possible mode of transmission of HDV?

  • Inhalation of infected air droplets
  • Sexual contact (correct)
  • Ingestion of contaminated food
  • Skin contact
  • Which cellular enzyme is responsible for HDV genomic RNA replication?

    <p>RNA polymerase II</p> Signup and view all the answers

    What is the morphology of HDV?

    <p>Enveloped, spherical, and pleiomorphic</p> Signup and view all the answers

    How does HDV enter the cells?

    <p>Mediated by HBsAg protein</p> Signup and view all the answers

    Which type of disease can superinfection of HDV cause?

    <p>Severe acute disease</p> Signup and view all the answers

    What is the prevailing genotype of HDV in Europe?

    <p>Genotype 1</p> Signup and view all the answers

    What are the possible modes of transmission of HDV?

    <p>Injecting drug use</p> Signup and view all the answers

    What is the only protein encoded by the HDV genome?

    <p>HDAg</p> Signup and view all the answers

    What is the morphology of HDV?

    <p>Spherical and pleiomorphic</p> Signup and view all the answers

    What is the replication cycle of HDV?

    <p>Genomic RNA replication is operated by viral RNA polymerase</p> Signup and view all the answers

    What is the most common genotype of HDV in Europe?

    <p>Genotype 1</p> Signup and view all the answers

    Which type of exposure can transmit HDV through sex contact?

    <p>Permucosal exposure</p> Signup and view all the answers

    What is the characteristic histological feature of acute HDV infection in the liver?

    <p>Presence of inflammatory cells in the parenchyma and portal areas</p> Signup and view all the answers

    Which protein is associated with the viral genome and is the only protein encoded by the HDV genome?

    <p>HDAg protein</p> Signup and view all the answers

    What is the morphology of HDV?

    <p>Spherical and slightly pleiomorphic</p> Signup and view all the answers

    What is the replication cycle of HDV?

    <p>Genomic RNA replication in the nucleus operated by cellular RNA polymerase II followed by cuts and autocatalytic ligation of genome and antigenome to produce the mRNA encoding S and L forms of HDAg</p> Signup and view all the answers

    Which protein is associated with the HDV viral genome and is the only protein encoded by the HDV genome?

    <p>HDAg protein</p> Signup and view all the answers

    What is the morphology of HDV?

    <p>Spherical and slightly pleiomorphic</p> Signup and view all the answers

    What is the replication cycle of HDV?

    <p>Genomic RNA replication in the nucleus operated by cellular RNA polymerase II</p> Signup and view all the answers

    Which type of exposure can transmit HDV through sex contact?

    <p>Permucosal exposure</p> Signup and view all the answers

    What is the prevailing genotype of HDV in Europe?

    <p>Genotype 1</p> Signup and view all the answers

    What is the type of infection associated with superinfection of HDV?

    <p>Chronic infection</p> Signup and view all the answers

    Which type of HDV infection is associated with chronic disease?

    <p>Superinfection</p> Signup and view all the answers

    What is the prevailing genotype of HDV in Europe?

    <p>Genotype 1</p> Signup and view all the answers

    Which type of exposure can transmit HDV through injecting drug use?

    <p>Percutaneous exposure</p> Signup and view all the answers

    Which protein is associated with the HDV viral genome and is the only protein encoded by the HDV genome?

    <p>HDAg protein</p> Signup and view all the answers

    What is the possible mode of entry of HDV into the cells?

    <p>Mediated by HBsAg</p> Signup and view all the answers

    What is the morphology of HDV?

    <p>Spherical, slightly pleiomorphic envelope</p> Signup and view all the answers

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