Hashimoto Thyroiditis - Microscopic Features Quiz

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What is the primary cause of the granulomatous response seen in de Quervain's thyroiditis?

Breakdown of thyroid follicles and release of colloid (correct)

Autoimmune process targeting the thyroid gland

Viral infection of the thyroid gland

Fibrosis and infiltration of mononuclear cells

What is the most common cause of the post-viral syndrome seen in de Quervain's thyroiditis?

Mumps virus

Coxsackie virus (correct)

Adenovirus

Epstein-Barr virus

Which of the following is a characteristic clinical feature of Hashimoto's thyroiditis?

Compensatory increase in TSH levels (correct)

Unilateral or bilateral thyroid enlargement

Painful and tender thyroid gland

Granulomatous inflammation with multinucleated giant cells

What is the most common microscopic finding in the early stage of Hashimoto's thyroiditis?

Diffuse mixed inflammatory infiltrate Signup and view all the answers

Which of the following is the most characteristic clinical feature of Hashimoto's thyroiditis?

Hypothyroidism Signup and view all the answers

What is the most common microscopic feature of the chronic stage of Hashimoto's thyroiditis?

Mononuclear cell infiltration and fibrosis Signup and view all the answers

What clinical feature is commonly observed in Hashimoto thyroiditis?

Painless enlargement of the thyroid Signup and view all the answers

Which of the following is a microscopic feature of Hashimoto thyroiditis?

Presence of Hurthle cells Signup and view all the answers

What is a common histological finding in Hashimoto thyroiditis?

Germinal centers Signup and view all the answers

What is a typical age group that Hashimoto thyroiditis commonly affects?

Middle-aged women Signup and view all the answers

Which of the following statements is true about the clinical course of Hashimoto thyroiditis?

Hypothyroidism develops gradually in the usual course Signup and view all the answers

What is a characteristic feature of Hashimoto thyroiditis on the cut surface of the thyroid gland?

Yellow-brown coloration with partial nodularity Signup and view all the answers

Which autoimmune disease is characterized by thyroid follicles being destroyed by T cells and antibodies?

Hashimoto thyroiditis Signup and view all the answers

In Hashimoto thyroiditis, which of the following autoantibodies are commonly found in the microsomes?

Anti-thyroid peroxidase antibodies Signup and view all the answers

Which of the following is a common clinical feature of Hashimoto thyroiditis?

Increased risk of B cell lymphoma Signup and view all the answers

Hashimoto thyroiditis is more common in which demographic group?

Females aged 25-45 Signup and view all the answers

Which syndrome has a significantly higher probability of Hashimoto's disease?

Down syndrome Signup and view all the answers

What is the microscopic feature of Hashimoto thyroiditis regarding the destruction of thyroid follicles?

Destruction by T cells and antibodies Signup and view all the answers