Hashimoto Thyroiditis - Microscopic Features Quiz
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Questions and Answers

What is the primary cause of the granulomatous response seen in de Quervain's thyroiditis?

  • Breakdown of thyroid follicles and release of colloid (correct)
  • Autoimmune process targeting the thyroid gland
  • Viral infection of the thyroid gland
  • Fibrosis and infiltration of mononuclear cells

What is the most common cause of the post-viral syndrome seen in de Quervain's thyroiditis?

  • Mumps virus
  • Coxsackie virus (correct)
  • Adenovirus
  • Epstein-Barr virus

Which of the following is a characteristic clinical feature of Hashimoto's thyroiditis?

  • Compensatory increase in TSH levels (correct)
  • Unilateral or bilateral thyroid enlargement
  • Painful and tender thyroid gland
  • Granulomatous inflammation with multinucleated giant cells

What is the most common microscopic finding in the early stage of Hashimoto's thyroiditis?

<p>Diffuse mixed inflammatory infiltrate (D)</p> Signup and view all the answers

Which of the following is the most characteristic clinical feature of Hashimoto's thyroiditis?

<p>Hypothyroidism (B)</p> Signup and view all the answers

What is the most common microscopic feature of the chronic stage of Hashimoto's thyroiditis?

<p>Mononuclear cell infiltration and fibrosis (C)</p> Signup and view all the answers

What clinical feature is commonly observed in Hashimoto thyroiditis?

<p>Painless enlargement of the thyroid (C)</p> Signup and view all the answers

Which of the following is a microscopic feature of Hashimoto thyroiditis?

<p>Presence of Hurthle cells (D)</p> Signup and view all the answers

What is a common histological finding in Hashimoto thyroiditis?

<p>Germinal centers (C)</p> Signup and view all the answers

What is a typical age group that Hashimoto thyroiditis commonly affects?

<p>Middle-aged women (D)</p> Signup and view all the answers

Which of the following statements is true about the clinical course of Hashimoto thyroiditis?

<p>Hypothyroidism develops gradually in the usual course (B)</p> Signup and view all the answers

What is a characteristic feature of Hashimoto thyroiditis on the cut surface of the thyroid gland?

<p>Yellow-brown coloration with partial nodularity (A)</p> Signup and view all the answers

Which autoimmune disease is characterized by thyroid follicles being destroyed by T cells and antibodies?

<p>Hashimoto thyroiditis (B)</p> Signup and view all the answers

In Hashimoto thyroiditis, which of the following autoantibodies are commonly found in the microsomes?

<p>Anti-thyroid peroxidase antibodies (A)</p> Signup and view all the answers

Which of the following is a common clinical feature of Hashimoto thyroiditis?

<p>Increased risk of B cell lymphoma (A)</p> Signup and view all the answers

Hashimoto thyroiditis is more common in which demographic group?

<p>Females aged 25-45 (B)</p> Signup and view all the answers

Which syndrome has a significantly higher probability of Hashimoto's disease?

<p>Down syndrome (B)</p> Signup and view all the answers

What is the microscopic feature of Hashimoto thyroiditis regarding the destruction of thyroid follicles?

<p>Destruction by T cells and antibodies (B)</p> Signup and view all the answers

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