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Hair Follicle Anatomy

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110 Questions

What is the primary function of the periderm layer during embryonic development?

To provide a protective barrier against amniotic fluid

What is the role of Notch signaling in the differentiation of spinous cells?

Notch signaling directs spinous cells to continue differentiating and migrate towards the surface of the skin

Which of the following cell types is NOT found in the intermediate layer of the embryonic skin?

Cornified cells

Which of the following is a unique property of the basal layer of the epidermis?

The basal layer is composed of multipotent epithelial cells

What is the primary function of the hair placodes that form in the underlying dermis?

To give rise to hair follicles

Which of the following cell types is responsible for the formation of the granular layer and cornified layer of the epidermis?

Spinous cells

Which layer of the hair follicle is heavily keratinized and has a fish-scale appearance?

Cuticle

Which layer of the hair follicle is pigmented and non-keratinized?

Medulla

Which cells in the hair follicle produce the cortex of the hair shaft?

Lateral cells (B)

During which phase of the hair growth cycle does the hair shaft exit the follicle?

Exogen

Which structure in the hair follicle contains capillaries and is covered by cells that form the hair root and develop into the hair shaft?

Dermal papilla

During which phase of the hair growth cycle does cell division cease in the bulb, the papilla shrinks, and the shaft and inner root sheath detach from the dermal papilla?

Catagen

Which of the following statements accurately describes the relationship between the external root sheath and the epidermis?

The external root sheath is continuous with the epidermis.

At what level do the cells of the internal root sheath disappear?

At the level of the sebaceous gland ducts

Which of the following statements accurately describes the origin and insertion of the arrector pili muscle?

It originates in the connective tissue sheath of the hair follicle and inserts into the papillary layer of the dermis.

Which of the following statements accurately describes the development of the epidermis?

The multipotent epithelial cells in the surface ectoderm become the embryonic epidermal basal layer.

Which of the following statements accurately describes the function of the basement membrane in the development of the epidermis?

The basement membrane separates the epidermis from the dermis and provides epidermal basal cells with growth factors.

Which of the following statements accurately describes the attachment of basal cells to the basement membrane?

Basal cells attach to the basement membrane through focal adhesions and hemidesmosomes composed of integrins.

What marks the transition from stage 4 to stage 5 of hair follicle development?

Formation of inner root sheath

Which stage is characterized by the formation of a spherical dermal papilla adjacent to the hair peg?

Stage 3

At which stage does the hair shaft begin to form at the upper end of the hair follicle?

Stage 6

During which stage does the dermal papilla become fully enclosed?

Stage 8

What happens to the hair shaft in stage 7 of hair follicle development?

It leaves the inner root sheath

Which stage involves the elongation of the inner root sheath up the hair follicle?

Stage 5

Which layer of the epidermis is responsible for the production of melanin?

Stratum basale

What is the primary function of the stratum lucidum layer?

Protection from UV radiation

Which layer of the epidermis contains Langerhans' cells, which play a role in the immune response?

Stratum spinosum

What is the characteristic appearance of cells in the stratum spinosum layer under a light microscope?

Spiny projections

Which layer of the epidermis contains the stem cells responsible for cell division and renewal?

Stratum basale

Which division of the brachial plexus trunks is responsible for innervating the muscles of the anterior compartment of the arm and forearm?

Anterior divisions

What is the primary function of Merkel cells in the epidermis?

Mechanoreception

Which of the following structures does the brachial plexus NOT form?

Femoral nerve

Which part of the brachial plexus is responsible for providing sympathetic innervation?

The roots

Which cord of the brachial plexus is formed by the union of the anterior divisions of the superior and middle trunks?

Lateral cord

Which muscle(s) are innervated by the posterior divisions of the brachial plexus trunks?

Muscles of the posterior compartment of the arm and forearm

Which of the following disorders is NOT typically associated with damage to the brachial plexus?

Amyotrophic lateral sclerosis

Which nerve innervates the pectoralis major but also sends a loop to the medial pectoral nerve that innervates the pectoralis minor?

Lateral pectoral nerve

Which branch of the posterior cord receives fibers from C5 and C6 and innervates the superior portion of the subscapularis muscle?

Upper subscapular nerve

Which terminal branch of the posterior cord innervates the teres minor and deltoid muscles, as well as the glenohumeral joint and skin over the inferior part of the deltoid?

Axillary nerve

Which nerve emerges from both the medial and lateral cords and supplies all flexors of the forearm except for the flexor carpi ulnaris and the medial half of the flexor digitorum profundus?

Median nerve

Which branch of the brachial plexus can lead to an 'Ape Hand' deformity when injured?

Median nerve

The hand of benediction deformity is associated with damage to which nerve?

Median nerve

Which nerve supplies most of the intrinsic muscles of the hand including the hypothenar eminence, and skin on the medial side of the hand?

Ulnar nerve

Injury to which nerve results in 'wrist drop'?

Radial nerve

Which nerve supplies the biceps, coracobrachialis, and brachialis muscles?

Musculocutaneous nerve

Ape Hand deformity is associated with the compression of which nerve?

Median nerve

Waiter's tip deformity is characteristic of injury to which part of the brachial plexus?

Upper trunk

'Claw Hand' deformity is a result of injury to which nerve?

Ulnar nerve

Which of the following muscles are innervated by the lateral cord of the brachial plexus?

Flexor carpi radialis, Flexor digitorum profundus

Which nerve root compression is associated with the condition known as 'Klumpke's palsy'?

C7-T1

Which of the following muscles is innervated by the posterior cord of the brachial plexus?

Teres major

Which of the following conditions is NOT typically associated with brachial plexus injury?

Carpal tunnel syndrome

Which nerve root compression is associated with the condition known as 'Erb's palsy'?

C5-C6

Which of the following muscles is innervated by the medial cord of the brachial plexus?

Pronator teres

Which of the following muscles is innervated by the dorsal scapular nerve?

Rhomboids

A patient presents with winging of the scapula, which is indicative of a lesion involving which nerve?

Long thoracic nerve

Which of the following muscles is innervated by the nerve to subclavius?

Subclavius

A patient complains of dull, aching pain in the posterior shoulder region, which may indicate a lesion involving which nerve?

Suprascapular nerve

Which of the following muscles is responsible for abduction of the arm at the shoulder joint?

Supraspinatus

A lesion involving which nerve may lead to difficulty in protraction of the scapula during arm elevation?

Long thoracic nerve

Which nerve is responsible for innervating the majority of the intrinsic muscles of the hand, including the thenar eminence, as well as the skin on the medial side of the hand?

Median nerve

Which nerve branch of the brachial plexus is responsible for innervating the pectoralis major muscle, but also sends a communicating loop to the medial pectoral nerve that supplies the pectoralis minor muscle?

Lateral pectoral nerve

Which of the following conditions is characterized by the 'ape hand' deformity, resulting from damage to a specific nerve?

Median nerve injury

Which nerve branch of the brachial plexus is responsible for innervating the triceps brachii, anconeus, brachioradialis, and extensor muscles of the forearm, as well as providing cutaneous innervation to the posterior aspect of the arm and forearm?

Radial nerve

Injury to which nerve of the brachial plexus is associated with the characteristic 'winging of the scapula' deformity?

Long thoracic nerve

Which nerve of the brachial plexus is responsible for providing sympathetic innervation?

Rami communicantes

Which nerve supplies most of the intrinsic muscles of the hand including the hypothenar eminence, and skin on the medial side of the hand?

Ulnar nerve

Which nerve supplies the deltoid and teres minor muscles?

Axillary nerve

Injury to which nerve results in 'wrist drop'?

Radial nerve

Which brachial plexus injury results in 'Waiter’s tip deformity'?

Suprascapular nerve injury

Which nerve supplies the biceps, coracobrachialis, and brachialis muscles?

Musculocutaneous nerve

'Ape Hand' deformity is associated with injury to which nerve?

Radial nerve

Which of the following muscles is innervated by the axillary nerve, a terminal branch of the posterior cord?

Deltoid

Injury to which nerve can result in the 'waiter's tip' deformity, characterized by the inability to extend the wrist and fingers?

Radial nerve

Which of the following muscles is supplied by the thoracodorsal nerve, a branch of the posterior cord?

Latissimus dorsi

Which condition is associated with the compression of the C8 and T1 nerve roots, resulting in paralysis of the intrinsic muscles of the hand?

Klumpke's palsy

Which of the following muscles is innervated by the medial pectoral nerve, a branch of the medial cord?

Pectoralis minor

Injury to which nerve can result in the 'ape hand' deformity, characterized by the inability to abduct and oppose the thumb?

Median nerve

Which nerve is responsible for innervating the three thenar muscles, leading to atrophy known as 'ape hand' when damaged?

Median nerve

Which nerve emerges from both the medial and lateral cords of the brachial plexus and supplies all flexors of the forearm except for the flexor carpi ulnaris and the medial half of the flexor digitorum profundus?

Median nerve

Which brachial plexus nerve branch can result in an 'Ape Hand' deformity when injured?

Median nerve

Which part of the brachial plexus is responsible for providing sympathetic innervation?

Lateral cord

Which nerve root compression is associated with 'Erb's palsy,' a condition that affects the shoulder and arm muscles?

C5-C6

Which of the following conditions is NOT typically associated with brachial plexus injury?

Ape Hand deformity

Which of the following nerves innervates the rhomboid muscles?

Dorsal scapular nerve

Injury to which nerve can lead to the 'winged scapula' deformity?

Long thoracic nerve

Which nerve innervates the supraspinatus and infraspinatus muscles, as well as the glenohumeral (shoulder) joint?

Suprascapular nerve

Which nerve innervates the subclavius muscle and the sternoclavicular joint?

Nerve to subclavius

Injury to which nerve can cause an 'Ape Hand' deformity?

Ulnar nerve

Which of the following nerves innervates the serratus anterior muscle?

Long thoracic nerve

Which nerve branch of the brachial plexus is responsible for innervating the superior portion of the subscapularis muscle?

Upper subscapular nerve

Which of the following statements about the upper subscapular nerve is correct?

It receives fibers from the C5 and C6 nerve roots.

Injury to which nerve branch of the brachial plexus can result in winging of the scapula?

Long thoracic nerve

Which muscle is primarily innervated by the upper subscapular nerve?

Subscapularis

Where does the upper subscapular nerve originate from within the brachial plexus?

Posterior cord

Which of the following statements about the upper subscapular nerve is false?

It innervates the teres minor muscle.

Which nerve is responsible for innervating the supraspinatus, infraspinatus, and glenohumeral (shoulder) joint?

Suprascapular nerve

What is the course of the suprascapular nerve?

Passes laterally across the posterior triangle of the neck, through the scapular notch under the superior transverse scapular ligament

Which nerve arises from the anterior rami of C5-C7 and innervates the serratus anterior muscle?

Long thoracic nerve

Which nerve arises from the superior trunk receiving fibers from C5, C6, and often C4, and innervates the subclavius muscle and sternoclavicular joint?

Nerve to subclavius

Which nerve arises from the anterior ramus of C5 with a frequent contribution from C4, pierces the middle scalene, descends deep to the levator scapulae, and innervates the rhomboid muscles?

Dorsal scapular nerve

Which nerve is responsible for innervating the supraspinatus muscle and the glenohumeral (shoulder) joint, but not the infraspinatus muscle?

Suprascapular nerve

Which nerve supplies the superior portion of the subscapularis muscle?

Upper subscapular nerve

Which nerve passes posteriorly and enters the subscapularis muscle?

Lower subscapular nerve

Which nerve innervates the inferior portion of the subscapularis muscle and the teres major muscle?

Lower subscapular nerve

Which nerve supplies the teres minor and deltoid muscles?

Axillary nerve

Which nerve receives fibers from C5 and C6 and runs inferolaterally to innervate latissimus dorsi?

Thoracodorsal nerve

Which nerve descends posteriorly to innervate triceps brachii and anconeus?

Radial nerve

Which nerve originates from both the medial and lateral cords and supplies all flexors of the forearm except for flexor carpi ulnaris?

Median nerve

'Hand of Benediction' deformity is associated with damage to which nerve?

Median nerve

Test your knowledge on the anatomy of the hair follicle including the external and internal root sheath, hair shaft, glassy membrane, and more. Understand the relationships between the skin layers, arrector pili muscle, sebaceous, and sweat glands.

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