Haemoglobin Electrophoresis Test

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14 Questions

Haemoglobin F is the normal type of Haemoglobin found in healthy kids and adults.

False

Haemoglobin electrophoresis uses the principle of gel electrophoresis to separate out various types of Haemoglobin.

True

Haemoglobin S is the normal type of Haemoglobin found in healthy kids and adults.

False

Electrophoresis is a separation technique used to separate molecules according to their shape and colour.

False

Haemolytic anaemia is associated with abnormal levels of Haemoglobin A.

False

Haemoglobin electrophoresis test detects the excess of normal Haemoglobin.

False

The Haemoglobin Electrophoresis test is used to detect diseases involving abnormal Haemoglobin production.

True

Haemoglobin electrophoresis can detect sickle cell anaemia.

True

Fasting is required before taking the Haemoglobin Electrophoresis test.

False

Immunochemical Electrophoresis is not a type of electrophoresis.

False

The Haemoglobin Electrophoresis test can detect symptoms such as poor appetite and enlarged liver.

True

The specimen required for the Haemoglobin Electrophoresis test is a urine sample.

False

The Haemoglobin Electrophoresis test can detect bone problems, especially in the face.

True

The blood sample for the Haemoglobin Electrophoresis test is collected through a procedure called arteriopuncture.

False

Study Notes

Haemoglobin Electrophoresis

  • Haemoglobin electrophoresis is a test that detects various types of Haemoglobin in the blood using the principle of gel electrophoresis.

Types of Haemoglobin

  • Haemoglobin F: normal type found in foetuses and newborns, replaced by Haemoglobin A soon after birth.
  • Haemoglobin A: the normal type most commonly found in healthy kids and adults.
  • Haemoglobin S, C, D, and E: abnormal Haemoglobin types that can lead to blood disorders.

Electrophoresis

  • Electrophoresis is a separation technique used in clinical and research laboratories to separate molecules according to their size and electrical charge in a fluid or gel under the influence of an electric field.
  • Types of Electrophoresis:
    • Routine Electrophoresis
    • High Resolution Electrophoresis
    • Polyacrylamide gel Electrophoresis
    • Capillary Electrophoresis
    • Isoelectric Focussing
    • Immunochemical Electrophoresis
    • Two-dimensional Electrophoresis
    • Pulse field Electrophoresis

Haemoglobin Electrophoresis Test

  • The test is used to detect diseases involving abnormal Haemoglobin production, such as sickle cell diseases and thalassemia.
  • Symptoms screened for include slow growth and delayed puberty, bone problems, poor appetite, enlarged liver and spleen, dark urine, jaundice, and more.
  • No fasting or special preparations are required for the test, which involves collecting a blood sample through venipuncture.

This quiz covers the haemoglobin electrophoresis test, its principles, and the different types of haemoglobin in the blood. It discusses the normal and abnormal forms of haemoglobin and their detection.

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