Sickle Cell Anemia Diagnosis

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Questions and Answers

What is a common complication of sickle cell anemia that may require medical intervention?

  • Priapism (correct)
  • Bronchitis
  • Gingivitis
  • Sickle cell trait

Which of the following laboratory tests is typically abnormal in sickle cell anemia?

  • Thyroid function tests
  • Lipid panel
  • Urinalysis
  • Complete blood count (CBC) (correct)

What physical indication is characteristic of sickle cell anemia when examining a blood smear?

  • Sickleshaped red blood cells (correct)
  • Acanthocytes
  • Spherocytes
  • Teardrop cells

What is a common chronic complication of sickle cell anemia related to impaired blood flow and tissue damage?

<p>Leg ulcers (D)</p> Signup and view all the answers

Which laboratory test for sickle cell anemia evaluates different types of hemoglobin based on their electrical charge?

<p>Hemoglobin electrophoresis (C)</p> Signup and view all the answers

What may an elevated reticulocyte count indicate in a patient with sickle cell anemia?

<p>Increased red blood cell turnover and hemolysis (B)</p> Signup and view all the answers

What is a potential consequence of chronic vaso-occlusion and tissue ischemia in individuals with sickle cell anemia?

<p>Organ damage and dysfunction (D)</p> Signup and view all the answers

What is a common cause of bacterial infections in individuals with sickle cell anemia?

<p>Encapsulated organisms (B)</p> Signup and view all the answers

What is a medical emergency that requires immediate intervention in individuals with sickle cell anemia?

<p>Priapism (C)</p> Signup and view all the answers

What is a potential complication of sickle cell anemia that can cause permanent neurological damage or death?

<p>Stroke (D)</p> Signup and view all the answers

What may be required to alleviate symptoms and improve oxygen delivery to tissues in severe anemia?

<p>Blood transfusions (C)</p> Signup and view all the answers

What can trigger vaso-occlusive crises and acute chest syndrome in individuals with sickle cell anemia?

<p>Infections (C)</p> Signup and view all the answers

What is the most common mutation associated with sickle cell anemia in the HBB gene?

<p>A to T substitution in the sixth codon (B)</p> Signup and view all the answers

What is a hallmark feature of sickle cell disease?

<p>Vaso-occlusive crises (B)</p> Signup and view all the answers

What is a possible trigger for acute chest syndrome in sickle cell anemia?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary effect of chronic hemolysis in sickle cell anemia?

<p>Anemia (D)</p> Signup and view all the answers

What is the primary goal of genetic testing in sickle cell anemia?

<p>To identify carriers of the sickle cell trait (D)</p> Signup and view all the answers

What is a common symptom of anemia in sickle cell anemia?

<p>Fatigue (B)</p> Signup and view all the answers

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