Sickle Cell Anemia Diagnosis

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What is a common complication of sickle cell anemia that may require medical intervention?

Priapism

Which of the following laboratory tests is typically abnormal in sickle cell anemia?

Complete blood count (CBC)

What physical indication is characteristic of sickle cell anemia when examining a blood smear?

Sickleshaped red blood cells

What is a common chronic complication of sickle cell anemia related to impaired blood flow and tissue damage?

<p>Leg ulcers</p> Signup and view all the answers

Which laboratory test for sickle cell anemia evaluates different types of hemoglobin based on their electrical charge?

<p>Hemoglobin electrophoresis</p> Signup and view all the answers

What may an elevated reticulocyte count indicate in a patient with sickle cell anemia?

<p>Increased red blood cell turnover and hemolysis</p> Signup and view all the answers

What is a potential consequence of chronic vaso-occlusion and tissue ischemia in individuals with sickle cell anemia?

<p>Organ damage and dysfunction</p> Signup and view all the answers

What is a common cause of bacterial infections in individuals with sickle cell anemia?

<p>Encapsulated organisms</p> Signup and view all the answers

What is a medical emergency that requires immediate intervention in individuals with sickle cell anemia?

<p>Priapism</p> Signup and view all the answers

What is a potential complication of sickle cell anemia that can cause permanent neurological damage or death?

<p>Stroke</p> Signup and view all the answers

What may be required to alleviate symptoms and improve oxygen delivery to tissues in severe anemia?

<p>Blood transfusions</p> Signup and view all the answers

What can trigger vaso-occlusive crises and acute chest syndrome in individuals with sickle cell anemia?

<p>Infections</p> Signup and view all the answers

What is the most common mutation associated with sickle cell anemia in the HBB gene?

<p>A to T substitution in the sixth codon</p> Signup and view all the answers

What is a hallmark feature of sickle cell disease?

<p>Vaso-occlusive crises</p> Signup and view all the answers

What is a possible trigger for acute chest syndrome in sickle cell anemia?

<p>All of the above</p> Signup and view all the answers

What is the primary effect of chronic hemolysis in sickle cell anemia?

<p>Anemia</p> Signup and view all the answers

What is the primary goal of genetic testing in sickle cell anemia?

<p>To identify carriers of the sickle cell trait</p> Signup and view all the answers

What is a common symptom of anemia in sickle cell anemia?

<p>Fatigue</p> Signup and view all the answers

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