Podcast
Questions and Answers
What is the main cause of gout?
What is the main cause of gout?
- Elevated levels of monosodium urate crystals (correct)
- Infection in the synovial fluid
- Genetic mutation affecting joint structure
- Deposition of calcium crystals in synovial tissue
Where is gout particularly common?
Where is gout particularly common?
- Hand joints (correct)
- Hip joints
- Knee joints
- Shoulder joints
What percentage of hyperuricemia cases are due to renal under-excretion of uric acid?
What percentage of hyperuricemia cases are due to renal under-excretion of uric acid?
- Less than 10%
- Over 70% (correct)
- Around 20%
- 50%
Which joint is commonly affected in gout known as 'the king of diseases'?
Which joint is commonly affected in gout known as 'the king of diseases'?
What is the main source of uric acid formation in the body?
What is the main source of uric acid formation in the body?
What is the role of NALP-3 inflammasome in gout pathophysiology?
What is the role of NALP-3 inflammasome in gout pathophysiology?
Why is gout more common in men than in premenopausal women?
Why is gout more common in men than in premenopausal women?
What effect does obesity have on the risk of developing gout?
What effect does obesity have on the risk of developing gout?
How do MSU crystals induce inflammation in gout?
How do MSU crystals induce inflammation in gout?
Why is gout rare in premenopausal women compared to postmenopausal women?
Why is gout rare in premenopausal women compared to postmenopausal women?
What is the main cause of gout?
What is the main cause of gout?
Explain the term 'arthritis of the rich' in relation to gout.
Explain the term 'arthritis of the rich' in relation to gout.
What joint is particularly common in gout and referred to as 'the king of diseases'?
What joint is particularly common in gout and referred to as 'the king of diseases'?
What is the significance of hyperuricemia in the pathophysiology of gout?
What is the significance of hyperuricemia in the pathophysiology of gout?
What is the role of uric acid in the development of gout?
What is the role of uric acid in the development of gout?
Explain how hyperuricemia contributes to the pathophysiology of gout.
Explain how hyperuricemia contributes to the pathophysiology of gout.
What is the role of the NALP-3 inflammasome in gout inflammation?
What is the role of the NALP-3 inflammasome in gout inflammation?
Why is gout more common in men compared to women?
Why is gout more common in men compared to women?
What are the non-modifiable risk factors for gout?
What are the non-modifiable risk factors for gout?
Explain the connection between obesity and gout risk.
Explain the connection between obesity and gout risk.
