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Questions and Answers
What is the purpose of the first step in glycolysis, which involves phosphorylation of glucose?
What is the purpose of the first step in glycolysis, which involves phosphorylation of glucose?
- To prevent glucose from being transported out of the cell (correct)
- To trap glucose in the mitochondria
- To generate two molecules of ATP
- To convert glucose-6-P to fructose-6-P
Why is the conversion of glucose-6-P to fructose-6-P considered an isomerization reaction?
Why is the conversion of glucose-6-P to fructose-6-P considered an isomerization reaction?
- It leads to the release of carbon dioxide
- It results in the formation of water molecules
- It involves a change in the arrangement of atoms without losing any atoms (correct)
- It involves the generation of energy
Which enzyme is responsible for converting glucose-6-P to fructose-6-P in glycolysis?
Which enzyme is responsible for converting glucose-6-P to fructose-6-P in glycolysis?
- Aldolase
- Phosphofructokinase
- Phosphoglucose isomerase (correct)
- Hexokinase
What does the term 'kinases' typically do in biochemical reactions?
What does the term 'kinases' typically do in biochemical reactions?
Which enzyme catalyzes the irreversible phosphorylation of fructose-6-P at the second carbon to form fructose-1,6bisphosphate?
Which enzyme catalyzes the irreversible phosphorylation of fructose-6-P at the second carbon to form fructose-1,6bisphosphate?
What is the significance of the prefix 'bis' in bisphosphate?
What is the significance of the prefix 'bis' in bisphosphate?
Which molecule is formed by the cleavage of fructose-1,6-bisphosphate by aldolase?
Which molecule is formed by the cleavage of fructose-1,6-bisphosphate by aldolase?
What happens to dihydroxyacetone phosphate in the glycolytic pathway?
What happens to dihydroxyacetone phosphate in the glycolytic pathway?
What is the significance of a rise in fructose-1,6-bisP in the context of glycolysis?
What is the significance of a rise in fructose-1,6-bisP in the context of glycolysis?
Why does the liver perform glycolysis despite not needing energy for contraction?
Why does the liver perform glycolysis despite not needing energy for contraction?
How does pyruvate kinase activity respond to an increased flux through glycolysis?
How does pyruvate kinase activity respond to an increased flux through glycolysis?
What is one major role of glycolysis in the liver according to the text?
What is one major role of glycolysis in the liver according to the text?
What is the net reaction for the entire glycolysis pathway?
What is the net reaction for the entire glycolysis pathway?
In the formula ΔG = ΔG° + RT ln [C][D]/[A][B], what does ΔG° represent?
In the formula ΔG = ΔG° + RT ln [C][D]/[A][B], what does ΔG° represent?
Why is glycolysis considered irreversible as a pathway?
Why is glycolysis considered irreversible as a pathway?
What additional term is adopted for biochemical reactions to refer to the standard free energy change at pH 7?
What additional term is adopted for biochemical reactions to refer to the standard free energy change at pH 7?
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