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Questions and Answers
Which drug class reduces glucose absorption by decreasing the conversion of carbohydrates to monomers and increasing release of GLP-1?
Which drug class reduces glucose absorption by decreasing the conversion of carbohydrates to monomers and increasing release of GLP-1?
- Insulin
- Alpha-glucosidase inhibitors (correct)
- SGLT2 inhibitors
- Sulfonylureas
What is the mechanism of action of amylin analogs in reducing postprandial hyperglycemia?
What is the mechanism of action of amylin analogs in reducing postprandial hyperglycemia?
- Increased insulin secretion
- Inducing satiety and lowering appetite
- Decreased carbohydrate absorption (correct)
- Increased glucagon secretion
Which drug acts by activating dopamine D2 receptors to decrease hypothalamic activation?
Which drug acts by activating dopamine D2 receptors to decrease hypothalamic activation?
- Bromocriptine (correct)
- Insulin
- SGLT2 inhibitors
- Metformin
Which medication can be used as an adjunctive agent to insulin and has a main adverse effect of hypoglycemia?
Which medication can be used as an adjunctive agent to insulin and has a main adverse effect of hypoglycemia?
What is the primary function of glucagon in the body?
What is the primary function of glucagon in the body?
Which medication keeps the K+ ATP-channel on beta-cells open, leading to inhibition of insulin secretion?
Which medication keeps the K+ ATP-channel on beta-cells open, leading to inhibition of insulin secretion?
What is the main effect of diazoxide on insulin secretion?
What is the main effect of diazoxide on insulin secretion?
What is the role of Gs-coupled glucagon receptors activation in the body?
What is the role of Gs-coupled glucagon receptors activation in the body?
How do amylin analogs affect glucagon secretion in diabetic patients?
How do amylin analogs affect glucagon secretion in diabetic patients?
What is the main mechanism of action of A-glucosidase inhibitors acarbose and miglitol?
What is the main mechanism of action of A-glucosidase inhibitors acarbose and miglitol?
Which of the following hormones is known for acting via nuclear receptors to modulate gene transcription in target cells?
Which of the following hormones is known for acting via nuclear receptors to modulate gene transcription in target cells?
Which cell type in the endocrine pancreas produces insulin, proinsulin, C-peptide, and amylin?
Which cell type in the endocrine pancreas produces insulin, proinsulin, C-peptide, and amylin?
What is the primary function of somatostatin in the endocrine system?
What is the primary function of somatostatin in the endocrine system?
Which of the following hormones exerts rapid effects on signal transduction pathways via membrane receptors?
Which of the following hormones exerts rapid effects on signal transduction pathways via membrane receptors?
What type of hormone is insulin considered to be?
What type of hormone is insulin considered to be?
Which class of hormones includes insulin as one of its members?
Which class of hormones includes insulin as one of its members?
Metformin is commonly used to treat which condition?
Metformin is commonly used to treat which condition?
Sulfonylureas are medications commonly used to:
Sulfonylureas are medications commonly used to:
SGLT2 inhibitors are known to primarily act by:
SGLT2 inhibitors are known to primarily act by:
GLP-1 agonists are beneficial in diabetes as they:
GLP-1 agonists are beneficial in diabetes as they:
Metformin is unique because it does NOT typically cause:
Metformin is unique because it does NOT typically cause:
What is a common side effect associated with sulfonylureas use?
What is a common side effect associated with sulfonylureas use?
Which of the following best describes how metformin affects glucose production?
Which of the following best describes how metformin affects glucose production?
What is the main transporter for renal glucose reabsorption against the gradient?
What is the main transporter for renal glucose reabsorption against the gradient?
Which drug class primarily leads to increased glucose excretion via glycosuria?
Which drug class primarily leads to increased glucose excretion via glycosuria?
How does metformin affect insulin sensitivity?
How does metformin affect insulin sensitivity?
Which ADR is commonly associated with SGLT2 inhibitors?
Which ADR is commonly associated with SGLT2 inhibitors?
What is the major effect of SGLT2 inhibitors on glucose threshold for excretion?
What is the major effect of SGLT2 inhibitors on glucose threshold for excretion?
What distinguishes metformin from other antidiabetic drugs in terms of hypoglycemic risk?
What distinguishes metformin from other antidiabetic drugs in terms of hypoglycemic risk?
Which drug class mainly focuses on reducing glucose reabsorption in the kidneys?
Which drug class mainly focuses on reducing glucose reabsorption in the kidneys?