Podcast
Questions and Answers
Why do some insulins have a faster onset while others have a longer duration of action?
Why do some insulins have a faster onset while others have a longer duration of action?
- Variations in the molecular structure of the insulins (correct)
- Differences in the absorption rates of the insulins
- Presence of excipients in different insulins
- Formulation differences affecting the pharmacokinetics
What is the primary role of the formulation in insulin therapy?
What is the primary role of the formulation in insulin therapy?
- Determining the drug-drug interactions of insulin
- Affecting the speed of insulin absorption (correct)
- Influencing glucose excretion from the body
- Regulating insulin secretion from beta-cells
Which drug class promotes insulin secretion from beta-cells in T2DM?
Which drug class promotes insulin secretion from beta-cells in T2DM?
- Glucagon-like peptide-1 (GLP-1) agonists (correct)
- Sodium-glucose co-transporter 2 (SGLT-2) inhibitors
- Insulin sensitizers
- Alpha-glucosidase inhibitors
What is the mechanism of action of drugs that reduce glucose production in T2DM?
What is the mechanism of action of drugs that reduce glucose production in T2DM?
Which drug class reduces glucose production by inhibiting the mitochondrial respiration chain in the liver?
Which drug class reduces glucose production by inhibiting the mitochondrial respiration chain in the liver?
How do SGLT2 inhibitors primarily lower blood glucose levels?
How do SGLT2 inhibitors primarily lower blood glucose levels?
Which of the following best describes the mechanism of action of Biguanides like Metformin?
Which of the following best describes the mechanism of action of Biguanides like Metformin?
What is a common adverse drug reaction associated with SGLT2 inhibitors?
What is a common adverse drug reaction associated with SGLT2 inhibitors?
What is a distinguishing characteristic of the altered energy metabolism in patients with diabetes mellitus?
What is a distinguishing characteristic of the altered energy metabolism in patients with diabetes mellitus?
Which of the following describes a key feature of insulin resistance in type 2 diabetes mellitus?
Which of the following describes a key feature of insulin resistance in type 2 diabetes mellitus?
In T2DM, what is the relationship between insulin resistance, insulin production, and blood glucose levels over time?
In T2DM, what is the relationship between insulin resistance, insulin production, and blood glucose levels over time?
What distinguishes the secretion of insulin over time during food intake in T2DM compared to a healthy situation?
What distinguishes the secretion of insulin over time during food intake in T2DM compared to a healthy situation?
What is a characteristic difference between type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) in terms of insulin responsiveness?
What is a characteristic difference between type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) in terms of insulin responsiveness?
How does regular insulin differ from rapid-acting insulin in terms of its absorption and duration of action?
How does regular insulin differ from rapid-acting insulin in terms of its absorption and duration of action?
What is a key difference between the forms of available insulins for the treatment of type 1 diabetes mellitus?
What is a key difference between the forms of available insulins for the treatment of type 1 diabetes mellitus?
'How do bile acid sequestrants like colesevelam contribute to lowering blood glucose levels in type 2 diabetes mellitus (T2DM)?'
'How do bile acid sequestrants like colesevelam contribute to lowering blood glucose levels in type 2 diabetes mellitus (T2DM)?'
'What is the primary difference between the pharmacotherapy for type 1 diabetes mellitus (T1DM) and that for endogenous insulin secretion?'
'What is the primary difference between the pharmacotherapy for type 1 diabetes mellitus (T1DM) and that for endogenous insulin secretion?'
