COPY: Gluconeogenesis Pathway and Reactions
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Questions and Answers

What is the primary function of gluconeogenesis?

To generate glucose from non-carbohydrate sources such as amino acids, lactate, and glycerol.

Which enzyme is responsible for converting pyruvate to oxaloacetate in the gluconeogenic pathway?

Pyruvate carboxylase

What is the role of phosphoenolpyruvate carboxykinase in the gluconeogenic pathway?

It converts oxaloacetate to phosphoenolpyruvate (PEP).

Which hormone stimulates gluconeogenesis?

<p>Glucagon and cortisol</p> Signup and view all the answers

What is the role of glucose-6-phosphatase in the gluconeogenic pathway?

<p>It converts glucose-6-phosphate to glucose.</p> Signup and view all the answers

What is the significance of gluconeogenesis in maintaining brain function?

<p>Gluconeogenesis provides glucose for the brain, which relies heavily on glucose for energy.</p> Signup and view all the answers

How does energy status affect gluconeogenesis?

<p>Gluconeogenesis is increased during fasting or starvation when energy stores are low.</p> Signup and view all the answers

What is the role of gluconeogenesis in supporting red blood cell function?

<p>Gluconeogenesis provides glucose for red blood cells, which lack the ability to convert fatty acids to energy.</p> Signup and view all the answers

How does gluconeogenesis regulate blood sugar levels?

<p>Gluconeogenesis helps to regulate blood sugar levels by producing glucose when needed.</p> Signup and view all the answers

What is the significance of substrate availability in regulating gluconeogenesis?

<p>Availability of gluconeogenic precursors such as lactate, glycerol, and amino acids regulates gluconeogenesis.</p> Signup and view all the answers

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