Glomerular Filtration Rate (GFR) Tests

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10 Questions

What is the recommended way to report eGFR results below 60 mL/min?

Report with numerical values (e.g. 59 mL/min)

What is the molecular weight of cystatin C?

13359

What happens to cystatin C in the glomerulus?

It is filtered readily

According to KDIGO stages, what is the eGFR range for Stage 3 chronic kidney disease?

45-59 mL/min/1.73m

What is the primary advantage of using cystatin C to measure GFR?

It is less affected by muscle mass

What is the eGFR range for end-stage renal disease?

Less than 15 mL/min/1.73m

What is the role of renal tubular cells in cystatin C processing?

They reabsorb and break down cystatin C

Which KDIGO stage has an eGFR greater than 90 mL/min/1.73m?

Stage 1

Why is cystatin C a useful marker of GFR?

It is filtered by the glomerulus and reabsorbed by the tubules

What is the recommended formula to use when serum creatinine methods do not compare to the IDSM standard?

The formula recommended in the Historical Note

Learn about the standard tests used to measure the glomerular filtration rate, including clearance tests and the substances used to measure GFR. Understand the newer methods that have replaced older tests.

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