Glandular Metaplasia and Esophageal Pathology
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Glandular Metaplasia and Esophageal Pathology

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Questions and Answers

What is another name for metaplasia of the normal esophageal lining into intestinal glandular columnar epithelium?

Barret esophagus

What condition may glandular metaplasia of the esophageal lining lead to?

  • Esophageal adenocarcinoma (correct)
  • Chronic gastritis
  • Esophageal squamous cell carcinoma
  • Barret esophagus
  • Eosinophilic Mallory bodies are found in the hepatocytes in which condition?

    Alcoholic steatohepatitis

    Match the following terms with their correct definitions:

    <p>Mallory bodies = Characteristic for alcoholic steatohepatitis in liver Gastric ulcer = Punched-out defect with smooth and clean base Gastrointestinal stromal tumor (GIST) = Type of tumor found in the gastrointestinal tract Ulcerative colitis = Chronic transmural inflammation in colon</p> Signup and view all the answers

    Study Notes

    Glandular Metaplasia of Surface Squamous Epithelium

    • Also known as Barrett's esophagus
    • Caused by Gastro-esophageal reflux disease (GERD)
    • Fate: may lead to esophageal adenocarcinoma

    Esophageal Carcinoma

    • Types: Squamous cell carcinoma, Adenocarcinoma
    • Squamous cell carcinoma: common in upper third of esophagus
    • Adenocarcinoma: common in lower third of esophagus

    Gastric Carcinoma

    • Types: Adenocarcinoma (intestinal type, diffuse infiltrating type)
    • May cause linitis plastica or leather bottle appearance
    • May lead to ulcerated, infiltrative, or metastatic carcinoma

    Bowel Diseases

    • Crohn's disease: chronic transmural inflammation and noncaseating granulomas
    • Ulcerative colitis: may lead to adenocarcinoma
    • Chronic calcular cholecystitis: causes gallstones

    Pancreatic Tumors

    • Pancreatic duct adenocarcinoma
    • Pleomorphic adenoma: triphasic

    Liver Diseases

    • Liver Cirrhosis
    • Fatty change of liver (Steatosis): characterized by fat globules in hepatocytes
    • Mallory bodies: characteristic of alcoholic steatohepatitis
    • Focal nodular hyperplasia: benign tumor
    • Hepatocellular carcinoma: primary liver cancer
    • Regenerative Cirrhotic Nodule: benign tumor

    Other Tumors

    • Mucoepidermoid carcinoma
    • Warthin tumor
    • Gastrointestinal stromal tumor (GIST)
    • Tongue squamous cell carcinoma
    • Leukoplakia: precursor to squamous cell carcinoma

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    Description

    Quiz on glandular metaplasia of surface squamous epithelium, also known as Barret esophagus, and its relation to esophageal cancer and other gastrointestinal disorders.

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