Gastrointestinal System Pathology for 3rd Year Medical Students
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Questions and Answers

What occurs in long-term takers of acid secretion inhibitors?

  • A pure form of parietal cell hypertrophy without hyperacidity (correct)
  • An immediate rebound of excess acid secretion
  • A permanent cessation of acid secretion
  • A complete absence of tumors in the esophagus

    • What is the classification of mucosal polyps?

  • Neoplastic and non-neoplastic with a mix of benign and malignant lesions
  • Benign and malignant with a mix of neoplastic and non-neoplastic lesions
  • Benign or malignant
  • Neoplastic or non-neoplastic (correct)

    • What is the composition of non-neoplastic gastric polyps?

  • A mixture of hyperplastic surface epithelium and smooth muscle tissue
  • A mixture of hyperplastic surface epithelium and cystically dilated glandular tissue (correct)
  • A mixture of hyperplastic surface epithelium and cartilage tissue
  • A mixture of hyperplastic surface epithelium and nerve tissue

    • What percentage of upper GI endoscopies identify polyps?

    <p>Up to 5% of upper GI endoscopies</p> Signup and view all the answers

    What is the characteristic of non-neoplastic gastric polyps?

    <p>They are small and sessile</p> Signup and view all the answers

    What percentage of gastric polyps are adenomas?

    <p>5% to 10%</p> Signup and view all the answers

    What is the characteristic of gastric adenomas in terms of number?

    <p>They are usually single</p> Signup and view all the answers

    What is the underlying cause of gastric gland hyperplasia in Zollinger-Ellison syndrome?

    <p>Gastrinoma</p> Signup and view all the answers

    What is the percentage of non-neoplastic polyps among gastric polyps?

    <p>Up to 90% of gastric polyps</p> Signup and view all the answers

    What is the characteristic feature of Ménétrier disease?

    <p>Profound hyperplasia of the surface mucous cells with accompanying glandular atrophy</p> Signup and view all the answers

    Where are most hyperplastic polyps commonly located?

    <p>Antrum</p> Signup and view all the answers

    What is the most common type of malignant tumor in the stomach?

    <p>Gastric adenocarcinoma</p> Signup and view all the answers

    What is the characteristic of adenomatous change in the stomach?

    <p>It covers a large region of flat gastric mucosa without forming a mass lesion</p> Signup and view all the answers

    What is the characteristic of inflammatory fibroid polyps in terms of location?

    <p>They are most frequently found in the distal stomach</p> Signup and view all the answers

    What is the characteristic of Hindgut carcinoid tumors?

    <p>Almost always benign and less than 2 cm in diameter</p> Signup and view all the answers

    Which of the following is associated with hyperplasia of the parietal and chief cells within gastric glands?

    <p>Hypertrophic-hypersecretory gastropathy</p> Signup and view all the answers

    What is the characteristic feature of hypertrophic gastropathy?

    <p>Giant cerebriform enlargement of the rugal folds of the gastric mucosa</p> Signup and view all the answers

    What is the common clinical importance of all three variants of hypertrophic gastropathy?

    <p>They may mimic infiltrative carcinoma or lymphoma of the stomach</p> Signup and view all the answers

    What is the most important prognostic factor for GI carcinoid tumors?

    <p>Location</p> Signup and view all the answers

    What is the clinical consequence of hypertrophic-hypersecretory gastropathy and Zollinger-Ellison syndrome?

    <p>Increased risk of peptic ulceration</p> Signup and view all the answers

    What is the percentage of gastric lymphomas associated with chronic gastritis and H.pylori infection?

    <p>&gt;80%</p> Signup and view all the answers

    What is the typical appearance of the chromatin texture in carcinoid tumors?

    <p>Fine and coarse clumps</p> Signup and view all the answers

    What is the term used to describe tumors that resemble smooth muscle cells?

    <p>Leiomyomas</p> Signup and view all the answers

    Which type of carcinoid tumors rarely metastasize and are generally cured by resection?

    <p>Foregut carcinoid tumors</p> Signup and view all the answers

    What percentage of all gastric malignancies do gastric lymphomas represent?

    <p>5%</p> Signup and view all the answers

    What can be seen in a large GIST tumor?

    <p>Necrosis or cystic changes</p> Signup and view all the answers

    What is the most common type of gastric lymphoma?

    <p>B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)</p> Signup and view all the answers

    What is the name given to the histopathological feature of MALT lymphoma characterized by atypical lymphocytes surrounding gastric glands?

    <p>Lymphoid epithelioid lesion</p> Signup and view all the answers

    What is the characteristic of the cut surface of a GIST tumor?

    <p>Tan and usually lacks the whirling smooth muscle pattern</p> Signup and view all the answers

    What type of cells can be exhibited by a GIST tumor microscopically?

    <p>Either spindle cells, epithelioid cells, or a mixture of both</p> Signup and view all the answers

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