Genome Read Alignment in Bioinformatics
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Questions and Answers

Which step of read alignment involves building a large index database from a reference genome and/or the set of reads?

  • Step 4
  • Step 2
  • Step 1 (correct)
  • Step 3
  • What data structure is presented as an example for storing the occurrence locations of extracted seeds in the reference genome?

  • Suffix tree
  • Hash table (correct)
  • Array
  • Linked list
  • What is the purpose of the seed-and-extend strategy in read alignment?

  • To quickly locate genomic subsequences
  • To collect all the seeds (correct)
  • To build a large index database
  • To store the reference genome
  • What is the name given to the parts of the read that match the reference without errors?

    <p>Seeds</p> Signup and view all the answers

    What does the reference aligner do if the seeds are long enough to exact match only a small number of places?

    <p>Collect all the seed</p> Signup and view all the answers

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