Podcast
Play an AI-generated podcast conversation about this lesson
Questions and Answers
What is required for a proto-oncogene to become an oncogene?
What is required for a proto-oncogene to become an oncogene?
- No mutation is required
- Inactivation by mutations
- Loss of function mutation
- Over-activation by mutations (correct)
What is the role of a tumour suppressor gene?
What is the role of a tumour suppressor gene?
- To inhibit cell division
- To promote cell growth
- To protect cells from cancer (correct)
- To induce apoptosis
What type of mutation is required for a tumour suppressor gene to contribute to cancer?
What type of mutation is required for a tumour suppressor gene to contribute to cancer?
- Loss of function mutation (correct)
- Gain of function mutation
- No mutation is required
- Either gain or loss of function mutation
What is the characteristic of a molecularly dominant gene?
What is the characteristic of a molecularly dominant gene?
Signup and view all the answers
Which of the following is an example of a tumour suppressor gene?
Which of the following is an example of a tumour suppressor gene?
Signup and view all the answers
What is the term for a gene that requires two defective copies to exhibit the oncogenic phenotype?
What is the term for a gene that requires two defective copies to exhibit the oncogenic phenotype?
Signup and view all the answers
What is the effect of a gain of function mutation in a proto-oncogene?
What is the effect of a gain of function mutation in a proto-oncogene?
Signup and view all the answers
What is the role of a proto-oncogene?
What is the role of a proto-oncogene?
Signup and view all the answers
Which of the following genes is an oncogene?
Which of the following genes is an oncogene?
Signup and view all the answers
What is the effect of a loss of function mutation in a tumour suppressor gene?
What is the effect of a loss of function mutation in a tumour suppressor gene?
Signup and view all the answers
