10 Questions
What is required for a proto-oncogene to become an oncogene?
Over-activation by mutations
What is the role of a tumour suppressor gene?
To protect cells from cancer
What type of mutation is required for a tumour suppressor gene to contribute to cancer?
Loss of function mutation
What is the characteristic of a molecularly dominant gene?
One defective copy of the gene is sufficient
Which of the following is an example of a tumour suppressor gene?
BRCA1
What is the term for a gene that requires two defective copies to exhibit the oncogenic phenotype?
Molecularly recessive
What is the effect of a gain of function mutation in a proto-oncogene?
Over-activation of the gene
What is the role of a proto-oncogene?
To help cells grow and divide
Which of the following genes is an oncogene?
RAS
What is the effect of a loss of function mutation in a tumour suppressor gene?
Inactivation of the gene
Learn about genetic variations, their role in making us unique, and how they affect our response to disease treatment. Discover the connection between genetic mutations and cancer.
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