Genetic Variations and Cancer
10 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is required for a proto-oncogene to become an oncogene?

  • No mutation is required
  • Inactivation by mutations
  • Loss of function mutation
  • Over-activation by mutations (correct)

    • What is the role of a tumour suppressor gene?

  • To inhibit cell division
  • To promote cell growth
  • To protect cells from cancer (correct)
  • To induce apoptosis

    • What type of mutation is required for a tumour suppressor gene to contribute to cancer?

  • Loss of function mutation (correct)
  • Gain of function mutation
  • No mutation is required
  • Either gain or loss of function mutation

    • What is the characteristic of a molecularly dominant gene?

    <p>One defective copy of the gene is sufficient</p> Signup and view all the answers

    Which of the following is an example of a tumour suppressor gene?

    <p>BRCA1</p> Signup and view all the answers

    What is the term for a gene that requires two defective copies to exhibit the oncogenic phenotype?

    <p>Molecularly recessive</p> Signup and view all the answers

    What is the effect of a gain of function mutation in a proto-oncogene?

    <p>Over-activation of the gene</p> Signup and view all the answers

    What is the role of a proto-oncogene?

    <p>To help cells grow and divide</p> Signup and view all the answers

    Which of the following genes is an oncogene?

    <p>RAS</p> Signup and view all the answers

    What is the effect of a loss of function mutation in a tumour suppressor gene?

    <p>Inactivation of the gene</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser