Introduction to Cancer: Types and Causes
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Questions and Answers

What is the main cause of cancer according to the text?

  • Contact with chemicals such as radon and asbestos
  • An accumulation of detrimental variation in the genome over a lifetime (correct)
  • Not having children
  • Mutation in BRCA1 and/or BRCA2 genes

Which type of cancer originates from connective tissue found in bones, tendons, cartilage, muscle, and fat?

  • Lymphoma
  • Leukemia
  • Carcinoma
  • Sarcoma (correct)

What is the most common risk factor for lung cancer according to the text?

  • Mutation in BRCA1 and/or BRCA2 genes
  • Exposure to chemicals such as radon and asbestos (correct)
  • Obesity
  • Oral contraceptive use

Which cancer is disproportionately more common among Orthodox Jewish women?

<p>Breast cancer (D)</p> Signup and view all the answers

What type of cancer originates in epithelial tissue found in the internal and external lining of the body?

<p>Carcinoma (C)</p> Signup and view all the answers

What percentage of lung cancer deaths in men are likely caused by smoking according to the text?

<p>70% (D)</p> Signup and view all the answers

What is a common risk factor for colon cancer according to the text?

<p>High-fiber and low red meat diet (D)</p> Signup and view all the answers

How do cancer cells differ from normal human cells in terms of replicative immortality?

<p>Cancer cells can greatly exceed the Hayflick's limit due to telomerase activity (C)</p> Signup and view all the answers

Which gene plays a central role in controlling cell growth and is discussed in the text?

<p>p53 Tumor Suppressor Gene (D)</p> Signup and view all the answers

What is a characteristic of cancer cells related to genome instability?

<p>Ability to continue dividing despite abnormal number of chromosomes or mutations (B)</p> Signup and view all the answers

Why do most cancer cells avoid normal growth suppressor signals at the G1 checkpoint?

<p>To continue proliferating (C)</p> Signup and view all the answers

What is the significance of the two-hit hypothesis in cancer-inducing genes?

<p>Both copies of the gene must be affected for the gene to induce cancer (C)</p> Signup and view all the answers

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