Introduction to Cancer: Types and Causes
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Questions and Answers

What is the main cause of cancer according to the text?

  • Contact with chemicals such as radon and asbestos
  • An accumulation of detrimental variation in the genome over a lifetime (correct)
  • Not having children
  • Mutation in BRCA1 and/or BRCA2 genes
  • Which type of cancer originates from connective tissue found in bones, tendons, cartilage, muscle, and fat?

  • Lymphoma
  • Leukemia
  • Carcinoma
  • Sarcoma (correct)
  • What is the most common risk factor for lung cancer according to the text?

  • Mutation in BRCA1 and/or BRCA2 genes
  • Exposure to chemicals such as radon and asbestos (correct)
  • Obesity
  • Oral contraceptive use
  • Which cancer is disproportionately more common among Orthodox Jewish women?

    <p>Breast cancer</p> Signup and view all the answers

    What type of cancer originates in epithelial tissue found in the internal and external lining of the body?

    <p>Carcinoma</p> Signup and view all the answers

    What percentage of lung cancer deaths in men are likely caused by smoking according to the text?

    <p>70%</p> Signup and view all the answers

    What is a common risk factor for colon cancer according to the text?

    <p>High-fiber and low red meat diet</p> Signup and view all the answers

    How do cancer cells differ from normal human cells in terms of replicative immortality?

    <p>Cancer cells can greatly exceed the Hayflick's limit due to telomerase activity</p> Signup and view all the answers

    Which gene plays a central role in controlling cell growth and is discussed in the text?

    <p>p53 Tumor Suppressor Gene</p> Signup and view all the answers

    What is a characteristic of cancer cells related to genome instability?

    <p>Ability to continue dividing despite abnormal number of chromosomes or mutations</p> Signup and view all the answers

    Why do most cancer cells avoid normal growth suppressor signals at the G1 checkpoint?

    <p>To continue proliferating</p> Signup and view all the answers

    What is the significance of the two-hit hypothesis in cancer-inducing genes?

    <p>Both copies of the gene must be affected for the gene to induce cancer</p> Signup and view all the answers

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