Quiz on Human Genetic Variability and Consequences

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Questions and Answers

Which type of genetic variation refers to large-scale changes in the human genome, such as copy number variations and translocations?

  • SNPs and microsatellites
  • Pathogenic mutations
  • Large scale germ-line genetic variation (correct)
  • Small scale germ-line genetic variation

What is the purpose of sexual reproduction in humans?

  • To ensure identical DNA bases
  • To adapt to new environmental stresses
  • To prevent genetic variations
  • To create genetic differences between individuals (correct)

When aligning two human genomes, how similar are they at the DNA level?

  • Identical at 90% of DNA bases
  • Identical at 100% of DNA bases
  • Identical at 50% of DNA bases
  • Identical at 99.9% of DNA bases (correct)

Which type of genetic mutation results in the introduction of a stop codon?

<p>Nonsense/stop (D)</p> Signup and view all the answers

What is the main characteristic of cancer cells that allows for rapid evolution?

<p>Genomic instability (B)</p> Signup and view all the answers

What is the purpose of genetic characterization in cancer research?

<p>To understand the nature of genetic variation in malignant cells (B)</p> Signup and view all the answers

Which type of genetic variation involves the exchange of DNA between two different chromosomes during meiosis?

<p>Translocations/transversions (A)</p> Signup and view all the answers

What is the incidence of trisomy 21 (Down syndrome) in newborns?

<p>Approximately 1:1000 (B)</p> Signup and view all the answers

Which type of genetic variation involves the deletion or duplication of relatively large sections of DNA (>1000 base-pairs)?

<p>Copy number variants (C)</p> Signup and view all the answers

What is the incidence of microsatellites in our genomes?

<p>Common (A)</p> Signup and view all the answers

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