Genetic Disorders and Cancer
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Questions and Answers

What is the end product of purine catabolism in humans?

  • Allantoin
  • Guanosine
  • Adenosine
  • Uric acid (correct)

What is the primary cause of gouty arthritis?

  • Inherited disorders of purine catabolism
  • Underexcretion of uric acid
  • Overproduction of uric acid
  • Abnormalities in renal excretion of uric acid (correct)

What is the name of the enzyme defective in Lesch-Nyhan syndrome?

  • Uricase
  • Phosphoribosylpyrophosphate synthetase
  • Xanthine oxidase
  • Hypoxanthine-guanine phosphoribosyl transferase (correct)

What is the primary function of DNA?

<p>Storage of genetic information (A)</p> Signup and view all the answers

What is a possible long-term result of DNA errors?

<p>All of the above (D)</p> Signup and view all the answers

What is the term for the process by which cells undergo programmed cell death?

<p>Apoptosis (B)</p> Signup and view all the answers

Which of the following is NOT a cause of DNA damage?

<p>Evolutionary change (D)</p> Signup and view all the answers

What is the term for the process by which cells repair DNA damage?

<p>DNA repair (B)</p> Signup and view all the answers

What is the term for the disorder caused by a defect in hypoxanthine-guanine phosphoribosyl transferase?

<p>Lesch-Nyhan syndrome (B)</p> Signup and view all the answers

What is the term for the disorder caused by a defect in phosphoribosylpyrophosphate synthetase?

<p>PRPP synthetase deficiency (C)</p> Signup and view all the answers

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