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Genetic Disorders and Cancer

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Questions and Answers

What is the end product of purine catabolism in humans?

Allantoin

Guanosine

Adenosine

Uric acid (correct)

What is the primary cause of gouty arthritis?

Inherited disorders of purine catabolism

Underexcretion of uric acid

Overproduction of uric acid

Abnormalities in renal excretion of uric acid (correct)

What is the name of the enzyme defective in Lesch-Nyhan syndrome?

Uricase

Phosphoribosylpyrophosphate synthetase

Xanthine oxidase

Hypoxanthine-guanine phosphoribosyl transferase (correct)

What is the primary function of DNA?

Storage of genetic information Signup and view all the answers

What is a possible long-term result of DNA errors?

All of the above Signup and view all the answers

What is the term for the process by which cells undergo programmed cell death?

Apoptosis Signup and view all the answers

Which of the following is NOT a cause of DNA damage?

Evolutionary change Signup and view all the answers

What is the term for the process by which cells repair DNA damage?

DNA repair Signup and view all the answers

What is the term for the disorder caused by a defect in hypoxanthine-guanine phosphoribosyl transferase?

Lesch-Nyhan syndrome Signup and view all the answers

What is the term for the disorder caused by a defect in phosphoribosylpyrophosphate synthetase?

PRPP synthetase deficiency Signup and view all the answers