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Genetic Analysis with ABI 310 Capillary Genetic Analyzer

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Genetic Analysis with ABI 310 Capillary Genetic Analyzer

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Questions and Answers

What are SNP detection technologies used for?

To scan for new polymorphisms and determine the allele(s) of a known polymorphism in target sequences.

What limits global SNP discovery?

Amount of funding available for the activity.

What has driven the evolution of SNP detection technologies?

The Human Genome Project.

What methods are commonly used for local, target, SNP discovery?

Direct DNA sequencing or denaturing high performance liquid chromatography (dHPLC). Signup and view all the answers

Why is there no single method able to meet all the needs of SNP studies?

The demand for SNP genotyping is great. Signup and view all the answers

What must be done to further improve SNP detection technologies?

Develop new approaches to lower costs and increase speed. Signup and view all the answers

What is the main focus of SNP genotyping?

Genotyping individuals. Signup and view all the answers

What is the significance of the nearly completed human genome sequence in SNP detection?

It provides the reference against which all other sequencing data can be compared. Signup and view all the answers

What is the current status of SNP genotyping methods?

Many robust methods are currently available. Signup and view all the answers

What has been the trend in the number of SNP genotyping methods in recent years?

The number of SNP genotyping methods has exploded. Signup and view all the answers