Podcast
Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App
Questions and Answers
Which enzyme deficiency is responsible for about half the cases of autosomal recessive SCID?
Which enzyme deficiency is responsible for about half the cases of autosomal recessive SCID?
- Recombinase (RAG1 or RAG2)
- Adenosine deaminase (ADA) (correct)
- Purine nucleotide phosphorylase (PNP)
- Endonuclease (Artemis)
Which type of cells are particularly susceptible to injury by purine metabolites in ADA deficiency?
Which type of cells are particularly susceptible to injury by purine metabolites in ADA deficiency?
- Proliferating cells
- B cells
- T cells
- Lymphocytes (correct)
Which gene mutation results in failure of B and T cell development?
Which gene mutation results in failure of B and T cell development?
- PNP gene
- RAG1 or RAG2 gene (correct)
- Artemis gene
- ADA gene
Which genetic abnormality is responsible for about half of the cases of SCID?
Which genetic abnormality is responsible for about half of the cases of SCID?
Signup and view all the answers
Which type of cells are deficient in SCID patients with mutations in the IL-2 receptor?
Which type of cells are deficient in SCID patients with mutations in the IL-2 receptor?
Signup and view all the answers
What is the underlying cause of SCID?
What is the underlying cause of SCID?
Signup and view all the answers
Flashcards are hidden until you start studying
