Gels and Hydrogels
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Questions and Answers

What property of gels allows them to behave like solids despite being mostly liquid?

  • Their semi-solid, jelly-like consistency
  • Their high water content
  • The absence of any crosslinks
  • The presence of a three-dimensional crosslinked network (correct)

    • Which type of gel is composed of a liquid organic phase entrapped in a three-dimensionally cross-linked network?

  • Organogel (correct)
  • Hydrogel
  • Ointment
  • Cream

    • Which type of topical formulation is best for covering large areas of the skin or to avoid the greasiness associated with an ointment?

  • Gel
  • Ointment
  • Cream (correct)
  • Paste

    • Which type of topical formulation is best for treating dry skin conditions, such as psoriasis?

    <p>Ointment</p> Signup and view all the answers

    What is the dispersion medium in hydrogels?

    <p>Water</p> Signup and view all the answers

    Which type of topical formulation is considered the best moisturizer?

    <p>Ointment</p> Signup and view all the answers

    What is the most common purpose of creams when applied to the skin or mucous membranes?

    <p>All of the above</p> Signup and view all the answers

    What is the typical composition of an ointment?

    <p>80% oil and 20% water</p> Signup and view all the answers

    Which of the following is a key characteristic of properly designed oil-in-water (O/W) creams?

    <p>Suitable for oozing wounds</p> Signup and view all the answers

    Which of the following is a type of water-in-oil (W/O) cream?

    <p>Cold creams</p> Signup and view all the answers

    Which of the following is a key requirement for the packaging of ointments?

    <p>Containers should be well-closed and light resistant</p> Signup and view all the answers

    What is the purpose of the Minimum Fill Test for ointments?

    <p>To ensure net weight and volume compliance</p> Signup and view all the answers

    Which of the following statements about hydrophilic bases is correct?

    <p>They require aqueous solutions to be incorporated.</p> Signup and view all the answers

    Which semisolid preparation contains the highest proportion of solid components?

    <p>Pastes</p> Signup and view all the answers

    Which of the following semisolid preparations is an emulsion system with a creamy white appearance and good spreadability over the skin?

    <p>Creams</p> Signup and view all the answers

    Which type of base is white petrolatum classified as?

    <p>Oleaginous</p> Signup and view all the answers

    Which of the following methods can be used to enhance percutaneous absorption of drugs from semisolid preparations?

    <p>All of the above</p> Signup and view all the answers

    Which of the following factors should be considered when formulating semisolid preparations for percutaneous absorption?

    <p>All of the above</p> Signup and view all the answers

    Which of the following is NOT a characteristic of oleaginous/hydrocarbon ointment bases?

    <p>They are water-soluble</p> Signup and view all the answers

    What is the primary purpose of using ointment bases?

    <p>To act as emollients or lubricating agents</p> Signup and view all the answers

    Which of the following statements about petrolatum, USP is correct?

    <p>It has a melting point range of 38°C - 60°C</p> Signup and view all the answers

    Which of the following is NOT a classification of ointment bases?

    <p>Emulsion bases</p> Signup and view all the answers

    What is the primary function of non-medicated ointments?

    <p>To provide their emollient or lubricating effect</p> Signup and view all the answers

    Which of the following statements about medicated ointments is NOT correct?

    <p>They are used as emollients or lubricating agents</p> Signup and view all the answers

    Which of the following is the primary purpose of using a levigating agent when incorporating insoluble substances into an ointment base?

    <p>To facilitate the dispersion of the insoluble substances into the base</p> Signup and view all the answers

    What is the recommended technique for incorporating insoluble substances into an ointment base?

    <p>Powdering the insoluble substances finely and mixing them with an equal amount of base until a smooth mixture is obtained, then adding the rest of the base in increments</p> Signup and view all the answers

    Which of the following is the primary purpose of melting the oil and water phases separately when preparing an emulsion-based ointment?

    <p>To allow for the incorporation of ingredients with different melting points</p> Signup and view all the answers

    Which type of ointment base is most suitable for incorporating insoluble substances?

    <p>Emulsion-based ointment</p> Signup and view all the answers

    What is the primary purpose of using a spatula with a long, broad blade when incorporating ingredients into an ointment base?

    <p>To ensure even distribution of the ingredients throughout the ointment</p> Signup and view all the answers

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